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Cells, Vol. 12, Pages 138: The Cytokine Network in Colorectal Cancer: Implications for New Treatment Strategies
Cells, Vol. 12, Pages 138: The Cytokine Network in Colorectal Cancer: Implications for New Treatment Strategies
Colorectal cancer (CRC) is one of the most frequent tumor entities worldwide with only limited therapeutic options. CRC is...
Cells, Vol. 12, Pages 135: CD301b+ Macrophages as Potential Target to Improve Orthodontic Treatment under Mild Inflammation
Cells, Vol. 12, Pages 135: CD301b+ Macrophages as Potential Target to Improve Orthodontic Treatment under Mild Inflammation
Due to improvements of quality of life and the demand for aesthetics, more and more people are choosing orthodontic treatm...
Cells, Vol. 12, Pages 134: Cell Type-Specific Pherophorins of Volvox carteri Reveal Interplay of Both Cell Types in ECM Biosynthesis
Cells, Vol. 12, Pages 134: Cell Type-Specific Pherophorins of Volvox carteri Reveal Interplay of Both Cell Types in ECM Biosynthesis
The spheroidal green algae Volvox carteri serves as a model system to investigate the formation of a complex, multifunctio...
Cells, Vol. 12, Pages 133: The Serum/Glucocorticoid-Regulated Kinase 1 Is Targeted by miR-19a in CD4+ T Cells
Cells, Vol. 12, Pages 133: The Serum/Glucocorticoid-Regulated Kinase 1 Is Targeted by miR-19a in CD4+ T Cells
The polarization of CD4+ T cells into different T helper subsets is an important process in many diseases, including asthm...
Cells, Vol. 12, Pages 148: Gene Amplification in Tumor Cells: Developed De Novo or Adopted from Stem Cells
Cells, Vol. 12, Pages 148: Gene Amplification in Tumor Cells: Developed De Novo or Adopted from Stem Cells
Gene amplifications have been known for several decades as physiological processes in amphibian and flies, e.g., during eg...
Cells, Vol. 12, Pages 160: Sleep-Disturbance-Induced Microglial Activation Involves CRH-Mediated Galectin 3 and Autophagy Dysregulation
Cells, Vol. 12, Pages 160: Sleep-Disturbance-Induced Microglial Activation Involves CRH-Mediated Galectin 3 and Autophagy Dysregulation
Chronic sleep disturbances (CSDs) including insomnia, insufficient sleep time, and poor sleep quality are major public hea...
Cells, Vol. 12, Pages 151: Role of Heat Shock Proteins in Atrial Fibrillation: From Molecular Mechanisms to Diagnostic and Therapeutic Opportunities
Cells, Vol. 12, Pages 151: Role of Heat Shock Proteins in Atrial Fibrillation: From Molecular Mechanisms to Diagnostic and Therapeutic Opportunities
Heat shock proteins (HSPs) are endogenous protective proteins and biomarkers of cell stress response, of which examples ar...
Cells, Vol. 12, Pages 159: On the Origin and Evolution of Sperm Cells
Cells, Vol. 12, Pages 159: On the Origin and Evolution of Sperm Cells
Sperm cells have intrigued biologists since they were first observed nearly 350 years ago by Antonie van Leeuwenhoek and J...
Cells, Vol. 12, Pages 158: Calmodulin as a Key Regulator of Exosomal Signal Peptides
Cells, Vol. 12, Pages 158: Calmodulin as a Key Regulator of Exosomal Signal Peptides
Signal peptides (SPs) and their fragments play important roles as biomarkers and substances with physiological functions i...
Cells, Vol. 12, Pages 156: Delivery of CRISPR/Cas9 Plasmid DNA by Hyperbranched Polymeric Nanoparticles Enables Efficient Gene Editing
Cells, Vol. 12, Pages 156: Delivery of CRISPR/Cas9 Plasmid DNA by Hyperbranched Polymeric Nanoparticles Enables Efficient Gene Editing
Gene editing nucleases such as CRISPR/Cas9 have enabled efficient and precise gene editing in vitro and hold promise of ev...
Cells, Vol. 12, Pages 153: Utility of the Cerebral Organoid Glioma ‘GLICO’ Model for Screening Applications
Cells, Vol. 12, Pages 153: Utility of the Cerebral Organoid Glioma ‘GLICO’ Model for Screening Applications
Glioblastoma, a grade IV astrocytoma, is regarded as the most aggressive primary brain tumour with an overall median survi...
Cells, Vol. 12, Pages 154: Single-Cell Analysis 2.0
Cells, Vol. 12, Pages 154: Single-Cell Analysis 2.0
In 1665, Robert Hooke published his revolutionary book Micrographia [...]
Cells, Vol. 12, Pages 155: Preclinical Studies of Posttraumatic Headache and the Potential Therapeutics
Cells, Vol. 12, Pages 155: Preclinical Studies of Posttraumatic Headache and the Potential Therapeutics
Posttraumatic headache (PTH) attributed to traumatic brain injury (TBI) is a secondary headache developed within 7 days af...
Cells, Vol. 12, Pages 149: Diverse Begomoviruses Evolutionarily Hijack Plant Terpenoid-Based Defense to Promote Whitefly Performance
Cells, Vol. 12, Pages 149: Diverse Begomoviruses Evolutionarily Hijack Plant Terpenoid-Based Defense to Promote Whitefly Performance
Arthropod-borne pathogens and parasites are major threats to human health and global agriculture. They may directly or ind...
Cells, Vol. 12, Pages 121: Dendritic Cell-Based Vaccines Recruit Neutrophils to the Local Draining Lymph Nodes to Prime Natural Killer Cell Responses
Cells, Vol. 12, Pages 121: Dendritic Cell-Based Vaccines Recruit Neutrophils to the Local Draining Lymph Nodes to Prime Natural Killer Cell Responses
Dendritic cell (DC)-based cancer vaccines are a form of immunotherapy that activates the innate and adaptive immune system...
Cells, Vol. 12, Pages 111: Cardiac Neural Crest and Cardiac Regeneration
Cells, Vol. 12, Pages 111: Cardiac Neural Crest and Cardiac Regeneration
Neural crest cells (NCCs) are a vertebrate-specific, multipotent stem cell population that have the ability to migrate and...
Cells, Vol. 12, Pages 113: Pancreatic Islet Cells Response to IFNγ Relies on Their Spatial Location within an Islet
Cells, Vol. 12, Pages 113: Pancreatic Islet Cells Response to IFNγ Relies on Their Spatial Location within an Islet
Type 1 diabetes (T1D) is an auto-immune disease characterized by the progressive destruction of insulin-producing pancreat...
Cells, Vol. 12, Pages 122: Anti-Inflammatory Effect of Specialized Proresolving Lipid Mediators on Mesenchymal Stem Cells: An In Vitro Study
Cells, Vol. 12, Pages 122: Anti-Inflammatory Effect of Specialized Proresolving Lipid Mediators on Mesenchymal Stem Cells: An In Vitro Study
An interconnection between tissue inflammation and regeneration has been established through the regulation of defense and...
Cells, Vol. 12, Pages 129: Rhinovirus Suppresses TGF-β-GARP Presentation by Peripheral NK Cells
Cells, Vol. 12, Pages 129: Rhinovirus Suppresses TGF-β-GARP Presentation by Peripheral NK Cells
Asthma is a chronic airway disease whose exacerbations are often triggered by rhinovirus infection. TGF-β1 induce...
Cells, Vol. 12, Pages 127: Calcium Channels, OST1 and Stomatal Defence: Current Status and Beyond
Cells, Vol. 12, Pages 127: Calcium Channels, OST1 and Stomatal Defence: Current Status and Beyond
Stomatal immunity is regulated by pathogen-associated molecular patterns (PAMPs)- and abscisic acid (ABA)-triggered signal...
Cells, Vol. 12, Pages 126: SR Protein Kinase 1 Inhibition by TAF15
Cells, Vol. 12, Pages 126: SR Protein Kinase 1 Inhibition by TAF15
Although SRPKs were discovered nearly 30 years ago, our understanding of their mode of regulation is still limited. Regard...
Cells, Vol. 12, Pages 123: Exosomal miRNA Profiling in Vitreous Humor in Proliferative Diabetic Retinopathy
Cells, Vol. 12, Pages 123: Exosomal miRNA Profiling in Vitreous Humor in Proliferative Diabetic Retinopathy
MicroRNAs (miRNAs) are small noncoding RNAs which mediate some of the pathological mechanisms of diabetic retinopathy. The...
Cells, Vol. 12, Pages 125: iNOS Deletion in Alveolar Epithelium Cannot Reverse the Elastase-Induced Emphysema in Mice
Cells, Vol. 12, Pages 125: iNOS Deletion in Alveolar Epithelium Cannot Reverse the Elastase-Induced Emphysema in Mice
Background: Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. In addition to chr...
Cells, Vol. 12, Pages 120: Molecular Mechanisms and Clinical Application of Multipotent Stem Cells for Spinal Cord Injury
Cells, Vol. 12, Pages 120: Molecular Mechanisms and Clinical Application of Multipotent Stem Cells for Spinal Cord Injury
Spinal Cord Injury (SCI) is a common neurological disorder with devastating psychical and psychosocial sequelae. The major...
Cells, Vol. 12, Pages 112: The Long Telling Story of “Endothelial Progenitor Cells”: Where Are We at Now?
Cells, Vol. 12, Pages 112: The Long Telling Story of “Endothelial Progenitor Cells”: Where Are We at Now?
Endothelial progenitor cells (EPCs): The name embodies years of research and clinical expectations, but where are we now? ...
Cells, Vol. 12, Pages 118: Role of Mitochondrial Iron Overload in Mediating Cell Death in H9c2 Cells
Cells, Vol. 12, Pages 118: Role of Mitochondrial Iron Overload in Mediating Cell Death in H9c2 Cells
Iron overload (IO) is associated with cardiovascular diseases, including heart failure. Our study’s aim was to e...
Cells, Vol. 12, Pages 117: The Role of Iron and Cobalt in Gynecological Diseases
Cells, Vol. 12, Pages 117: The Role of Iron and Cobalt in Gynecological Diseases
Iron and cobalt are micronutrients that play an important role in the regulation of cellular processes, being part of the ...
Cells, Vol. 12, Pages 119: Fecal Microbiota Transplantation Reduces Pathology and Improves Cognition in a Mouse Model of Alzheimer’s Disease
Cells, Vol. 12, Pages 119: Fecal Microbiota Transplantation Reduces Pathology and Improves Cognition in a Mouse Model of Alzheimer’s Disease
Characterized by the presence of amyloid plaques, neurofibrillary tangles and neuroinflammation, Alzheimer’s dis...