SCI Abstract

search
+
Establishment and characterization of NCC-OS2-C1: a novel patient-derived cell line of osteosarcoma
Establishment and characterization of NCC-OS2-C1: a novel patient-derived cell line of osteosarcoma
Osteosarcoma is the most common primary bone sarcoma with a bimodal age distribution. Complete surgical resection with neo...
Establishment and characterization of novel cancer cachexia-inducing cell line, Aku60GC, of scirrhous gastric cancer
Establishment and characterization of novel cancer cachexia-inducing cell line, Aku60GC, of scirrhous gastric cancer
Cancer cachexia is a pathological state characterized by severe weight loss, skeletal muscle depletion, and adipose tissue...
LINC01559: roles, mechanisms, and clinical implications in human cancers
LINC01559: roles, mechanisms, and clinical implications in human cancers
Long intergenic non-protein coding RNA 1559 (LINC01559), a long non-coding RNA (lncRNA) located on chromosome 12p13.1, pla...
In vitro properties of four benign meningioma cells derived from WHO grade 1 meningiomas
In vitro properties of four benign meningioma cells derived from WHO grade 1 meningiomas
Meningiomas are common intracranial tumors arising from the meninges. They exhibit heterogeneity in their biological behav...
The influence of cell source on the senescence of human mesenchymal stem/stromal cells
The influence of cell source on the senescence of human mesenchymal stem/stromal cells
While mesenchymal stem/stromal cells (MSCs) exhibit the ability to self-renew, they are not immortal; they eventually reac...
Ovarian Leydig cells and neural crests
Ovarian Leydig cells and neural crests
In our search for markers to identify and study ovarian Leydig cells, we utilized immunohistochemical techniques and visua...
RFX5 promotes the progression of triple-negative breast cancer through transcriptional activation of JAG1
RFX5 promotes the progression of triple-negative breast cancer through transcriptional activation of JAG1
Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype characterized by high recurrence rates, low su...
SIX1 enhances aerobic glycolysis and progression in cervical cancer through ENO1
SIX1 enhances aerobic glycolysis and progression in cervical cancer through ENO1
Cervical cancer is a significant threat to women's health, and its incidence in China has been increasing in recent ye...
The role of MICAL2 in cancer progression: mechanisms, challenges, and therapeutic potential
The role of MICAL2 in cancer progression: mechanisms, challenges, and therapeutic potential
Cancer is the greatest threat to public health worldwide and a major cause of human death. Compared with conventional chem...
Clinical characteristics and induced pluripotent stem cells (iPSCs) disease model of Harel–Yoon syndrome caused by compound heterozygous ATAD3A variants
Clinical characteristics and induced pluripotent stem cells (iPSCs) disease model of Harel–Yoon syndrome caused by compound heterozygous ATAD3A variants
ATPase family AAA-domain-containing protein 3 A (ATAD3A) is enriched on the mitochondrial membrane and is essential ...
LncRNA OLMALINC promotes osteosarcoma progression through USP1-mediated autophagy suppression
LncRNA OLMALINC promotes osteosarcoma progression through USP1-mediated autophagy suppression
Osteosarcoma (OS) remains a challenging malignancy with poor prognosis, especially in metastatic or recurrent cases. Despi...
Hyaluronic acid-modified milk exosomes carrying ZNF516 inhibit ABCC5 and contribute to pemetrexed sensitivity in lung adenocarcinoma
Hyaluronic acid-modified milk exosomes carrying ZNF516 inhibit ABCC5 and contribute to pemetrexed sensitivity in lung adenocarcinoma
Lung adenocarcinoma (LUAD) is the most common subtype of lung cancer. Milk-derived exosomes (mEXOs) have critical roles in...
Establishment and characterization of NCC-PS2-C1: a novel cell line of high-grade pleomorphic spindle cell sarcoma, most consistent with myxofibrosarcoma
Establishment and characterization of NCC-PS2-C1: a novel cell line of high-grade pleomorphic spindle cell sarcoma, most consistent with myxofibrosarcoma
Pleomorphic sarcoma (PS) is a heterogeneous group of malignant mesenchymal tumors that lack specific histological differen...
Generation of human induced pluripotent stem cell lines derived from a patient carrying an intragenic deletion in the gene
Generation of human induced pluripotent stem cell lines derived from a patient carrying an intragenic deletion in the gene
Brain malformations with or without urinary tract defects (BRMUTD) are caused by heterozygous variants in the NFIA gene. B...
Deficiency of synaptotagmin-1 aggravates pressure overload-induced cardiac hypertrophy and dysfunction via the p38 MAPK signaling pathway in mice
Deficiency of synaptotagmin-1 aggravates pressure overload-induced cardiac hypertrophy and dysfunction via the p38 MAPK signaling pathway in mice
Cardiac hypertrophy is a major risk factor for heart failure and sudden cardiac death, but its molecular mechanisms have n...
Establishment and characterization of Cri Du Chat neuronal stem cells: a novel promising resource to study the syndrome
Establishment and characterization of Cri Du Chat neuronal stem cells: a novel promising resource to study the syndrome
The Cri Du Chat (CdC) Syndrome is a rare chromosome disease condition resulting from variable size deletion occurring on t...
Advanced glycation end products alter the structural integrity, increase the permeability and transform the biocompatibility of collagen within the peritoneal membrane
Advanced glycation end products alter the structural integrity, increase the permeability and transform the biocompatibility of collagen within the peritoneal membrane
In patients undergoing long-term peritoneal dialysis, the peritoneal accumulation of advanced glycation end-products (AGEs...
Sunitinib-resistant renal cell carcinoma cell-derived exosomes promote facilitation of tumor progression via secretion of the lncRNA SNHG16
Sunitinib-resistant renal cell carcinoma cell-derived exosomes promote facilitation of tumor progression via secretion of the lncRNA SNHG16
Renal cell carcinoma (RCC) is one of the most common tumors of high malignancy in the urological system. Sunitinib is comm...
Assessment of non-myelotoxic agents as a preparatory regimen for hematopoietic stem cell gene therapy
Assessment of non-myelotoxic agents as a preparatory regimen for hematopoietic stem cell gene therapy
RAG2 deficiency is characterized by a lack of B and T lymphocytes, causing severe lethal infections. Currently, RAG2 defic...
MiR-124-3p inhibits cell stemness in glioblastoma via targeting EPHA2 through ALKBH5-mediated m6A modification
MiR-124-3p inhibits cell stemness in glioblastoma via targeting EPHA2 through ALKBH5-mediated m6A modification
Glioblastoma (GBM) is the most aggressive form of glioma, characterized by high mortality and poor prognosis. Dysregulatio...
Adiponectin-induced activation of ERK1/2 drives fibrosis in retinal pigment epithelial cells
Adiponectin-induced activation of ERK1/2 drives fibrosis in retinal pigment epithelial cells
Adiponectin (APN), a vasoactive cytokine produced by adipocytes, has emerged as a critical player in retinal diseases. Ren...
Emodin regulated lactate metabolism by inhibiting MCT1 to delay non-small cell lung cancer progression
Emodin regulated lactate metabolism by inhibiting MCT1 to delay non-small cell lung cancer progression
Lung cancer is one of the most common malignant tumors in the world, with high incidence rate and mortality. Monocarboxyla...
Establishment and characterization of a patient-derived metastatic extraskeletal Ewing sarcoma cell line ES-ZSS-1
Establishment and characterization of a patient-derived metastatic extraskeletal Ewing sarcoma cell line ES-ZSS-1
The methods available for treating metastatic Ewing sarcoma (ES) are inadequate; thus, innovative therapeutic approaches n...
Establishment and characterization of NCC-SS6-C1: a novel patient-derived cell line of synovial sarcoma
Establishment and characterization of NCC-SS6-C1: a novel patient-derived cell line of synovial sarcoma
Synovial sarcoma (SS) is identified as a sarcoma with monomorphic blue spindle cells that display variable epithelial diff...
Cyclic tensile stress promotes osteogenic differentiation via upregulation of Piezo1 in human dental follicle stem cells
Cyclic tensile stress promotes osteogenic differentiation via upregulation of Piezo1 in human dental follicle stem cells
As periodontal progenitor cells, human dental follicle stem cells (hDFCs) play an important role in regenerative medicine ...
GABAA receptor modulation by the endocannabinoid system: insights into the regulatory mechanisms involving glutamine synthetase and MAPK mediators
GABAA receptor modulation by the endocannabinoid system: insights into the regulatory mechanisms involving glutamine synthetase and MAPK mediators
Baur R, Gertsch J, Sigel E. Do N-arachidonyl-glycine (NA-glycine) and 2-arachidonoyl glycerol (2-AG) share mode of action ...
Osteoarthritis rat serum-derived extracellular vesicles aggravate osteoarthritis development by inducing NLRP3-mediated pyroptotic cell death and cellular inflammation
Osteoarthritis rat serum-derived extracellular vesicles aggravate osteoarthritis development by inducing NLRP3-mediated pyroptotic cell death and cellular inflammation
Osteoarthritis (OA), degenerative joint disease, is the most prevalent form of arthritis worldwide. Besides its substantia...
Zebrafish larvae as a model for studying the impact of oral bacterial vesicles on tumor cell growth and metastasis
Zebrafish larvae as a model for studying the impact of oral bacterial vesicles on tumor cell growth and metastasis
Oral bacteria naturally secrete extracellular vesicles (EVs), which have attracted attention for their promising biomedica...
Sequencing-based study of neural induction of human dental pulp stem cells
Sequencing-based study of neural induction of human dental pulp stem cells
Techniques for triggering neural differentiation of embryonic and induced pluripotent stem cells into neural stem cells an...
Apelin-13 alleviates intrauterine adhesion by inhibiting epithelial–mesenchymal transition of endometrial epithelial cells and promoting angiogenesis
Apelin-13 alleviates intrauterine adhesion by inhibiting epithelial–mesenchymal transition of endometrial epithelial cells and promoting angiogenesis
Intrauterine adhesion (IUA) is a common complication of surgical manipulation of the uterine cavity such as abortion. The ...
Load More
format_indent_increase