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Improved prediction and risk stratification of major adverse cardiovascular events using an explainable machine learning approach combining plasma biomarkers and traditional risk factors
Improved prediction and risk stratification of major adverse cardiovascular events using an explainable machine learning approach combining plasma biomarkers and traditional risk factors
Cardiovascular diseases (CVD) remain the leading cause of morbidity and mortality globally. Traditional risk models, prima...
Elevated triglyceride-glucose index is a risk factor for cardiovascular events in adults with type 1 diabetes: a cohort study
Elevated triglyceride-glucose index is a risk factor for cardiovascular events in adults with type 1 diabetes: a cohort study
The triglyceride-glucose (TyG) index is recognized as an indicator of insulin resistance and is linked to cardiovascular d...
Associations between cardiometabolic indices and the onset of metabolic dysfunction-associated steatotic liver disease as well as its progression to liver fibrosis: a cohort study
Associations between cardiometabolic indices and the onset of metabolic dysfunction-associated steatotic liver disease as well as its progression to liver fibrosis: a cohort study
This study sought to examine the associations between cardiometabolic indices and the onset of metabolic dysfunction-assoc...
Metabolic rewiring and inter-organ crosstalk in diabetic HFpEF
Metabolic rewiring and inter-organ crosstalk in diabetic HFpEF
Heart failure with preserved ejection fraction (HFpEF) represents a significant and growing clinical challenge. Initially,...
Temporal prevalence and prognostic impact of diabetes mellitus and albuminuria in heart failure with preserved ejection fraction
Temporal prevalence and prognostic impact of diabetes mellitus and albuminuria in heart failure with preserved ejection fraction
Most patients with heart failure with preserved ejection fraction (HFpEF) have a metabolic phenotype in which comorbiditie...
Effects of adipose tissues on the relationship between type 2 diabetes mellitus and reduced heart rate variability: mediation analysis
Effects of adipose tissues on the relationship between type 2 diabetes mellitus and reduced heart rate variability: mediation analysis
Type 2 diabetes mellitus (T2DM) is associated with decreased heart rate variability (HRV) with an unclear intermediate mec...
Impact of baseline FIB-4 score on efpeglenatide benefits on cardiovascular outcomes in people with type 2 diabetes: a participant-level exploratory analysis of the AMPLITUDE-O trial
Impact of baseline FIB-4 score on efpeglenatide benefits on cardiovascular outcomes in people with type 2 diabetes: a participant-level exploratory analysis of the AMPLITUDE-O trial
To estimate the incidence of major adverse cardiovascular events (MACE), expanded MACE, and MACE or Death across Fibrosis-...
Exposure of cumulative atherogenic index of plasma and the development of prediabetes in middle-aged and elderly individuals: evidence from the CHARLS cohort study
Exposure of cumulative atherogenic index of plasma and the development of prediabetes in middle-aged and elderly individuals: evidence from the CHARLS cohort study
The impact of dynamic changes in the degree of atherosclerosis on the development of prediabetes remains unclear. This stu...
External validation and calibration of risk equations for prediction of diabetic kidney diseases among patients with type 2 diabetes in Taiwan
External validation and calibration of risk equations for prediction of diabetic kidney diseases among patients with type 2 diabetes in Taiwan
Most existing risk equations for predicting/stratifying individual diabetic kidney disease (DKD) risks were developed usin...
The relationship between repeated measurements of HbA1c and risk of coronary events among the common haptoglobin phenotype groups: the Action for Health in Diabetes (Look AHEAD) study
The relationship between repeated measurements of HbA1c and risk of coronary events among the common haptoglobin phenotype groups: the Action for Health in Diabetes (Look AHEAD) study
In the ACCORD study, participants with the haptoglobin (Hp) 2–2 phenotype and glycated hemoglobin (HbA1c) X...
Metabolic syndrome parameters' variability and stroke incidence in hypertensive patients: evidence from a functional community cohort
Metabolic syndrome parameters' variability and stroke incidence in hypertensive patients: evidence from a functional community cohort
Stroke is a common complication of hypertension, but the predictive value of metabolic syndrome parameters' variabilit...
Weight change and risk of incident type 2 diabetes: short, medium and long-term follow-up in tehran lipid and glucose study
Weight change and risk of incident type 2 diabetes: short, medium and long-term follow-up in tehran lipid and glucose study
Despite the high burden of obesity and Type 2 diabetes (T2DM) in the Middle East/West Asia region, the effect of weight ch...
Acute-to-chronic glycemic ratio as an outcome predictor in ischemic stroke in patients with and without diabetes mellitus
Acute-to-chronic glycemic ratio as an outcome predictor in ischemic stroke in patients with and without diabetes mellitus
Elevated plasma glucose levels are common in patients suffering acute ischemic stroke (AIS), and acute hyperglycemia has b...
Diabetic foot disease carries an intrinsic high risk of mortality and other severe outcomes in type 2 diabetes: a propensity score-matched retrospective population-based study
Diabetic foot disease carries an intrinsic high risk of mortality and other severe outcomes in type 2 diabetes: a propensity score-matched retrospective population-based study
To evaluate the association between diabetic foot disease (DFD) and the incidence of fatal and non-fatal events in individ...
Association of triglyceride-glucose index and its related parameters with atherosclerotic cardiovascular disease: evidence from a 15-year follow-up of Kailuan cohort
Association of triglyceride-glucose index and its related parameters with atherosclerotic cardiovascular disease: evidence from a 15-year follow-up of Kailuan cohort
Triglyceride glucose (TyG) index and its related parameters have been introduced as cost-effective surrogate indicators of...
Distribution and prognostic value of high-sensitivity cardiac troponin T and I across glycemic status: a population-based study
Distribution and prognostic value of high-sensitivity cardiac troponin T and I across glycemic status: a population-based study
Whether distributions and prognostic values of high-sensitivity cardiac troponin (hs-cTn) T and I are different across nor...
Link between triglyceride-glucose-body mass index and future stroke risk in middle-aged and elderly chinese: a nationwide prospective cohort study
Link between triglyceride-glucose-body mass index and future stroke risk in middle-aged and elderly chinese: a nationwide prospective cohort study
Current literature is deficient in robust evidence delineating the correlation between the triglyceride glucose-body mass ...
Intensive lifestyle intervention in type 2 diabetes and risk of incident coronary artery disease for the common haptoglobin phenotypes: the Look AHEAD study
Intensive lifestyle intervention in type 2 diabetes and risk of incident coronary artery disease for the common haptoglobin phenotypes: the Look AHEAD study
Intensive glycemic control reduced coronary artery disease (CAD) events among the Action to Control Cardiovascular Disease...
Insulin resistance and coronary inflammation in patients with coronary artery disease: a cross-sectional study
Insulin resistance and coronary inflammation in patients with coronary artery disease: a cross-sectional study
Insulin resistance (IR) is associated with coronary artery disease (CAD) severity. However, its underlying mechanisms are ...
Effect of SGLT-2 inhibitors on arrhythmia events: insight from an updated secondary analysis of > 80,000 patients (the SGLT2i—Arrhythmias and Sudden Cardiac Death)
Effect of SGLT-2 inhibitors on arrhythmia events: insight from an updated secondary analysis of > 80,000 patients (the SGLT2i—Arrhythmias and Sudden Cardiac Death)
We aimed to assess the effect of SGLT2i on arrhythmias by conducting a meta-analysis using data from randomized controlled...
Effects of exenatide on coronary stent’s endothelialization in subjects with type 2 diabetes: a randomized controlled trial. The Rebuild study
Effects of exenatide on coronary stent’s endothelialization in subjects with type 2 diabetes: a randomized controlled trial. The Rebuild study
Subjects with type 2 diabetes (T2D) have a higher risk of in-stent restenosis and stent thrombosis. The activation of the ...
Isthmin-1 (ISM1), a novel adipokine that reflects abdominal adipose tissue distribution in individuals with obesity
Isthmin-1 (ISM1), a novel adipokine that reflects abdominal adipose tissue distribution in individuals with obesity
The assessment of obesity-related health risks has traditionally relied on the Body Mass Index and waist circumference, bu...
Effects of diabetes mellitus and glycemic traits on cardiovascular morpho-functional phenotypes
Effects of diabetes mellitus and glycemic traits on cardiovascular morpho-functional phenotypes
The effects of diabetes on the cardiac and aortic structure and function remain unclear. Detecting and intervening these v...
Impact of stress hyperglycemia ratio, derived from glycated albumin or hemoglobin A1c, on mortality among ST-segment elevation myocardial infarction patients
Impact of stress hyperglycemia ratio, derived from glycated albumin or hemoglobin A1c, on mortality among ST-segment elevation myocardial infarction patients
Stress hyperglycemia ratio (SHR), associated with adverse outcomes in patients with ST-segment elevation myocardial infarc...
An elevated triglyceride-glucose index predicts adverse outcomes and interacts with the treatment strategy in patients with three-vessel disease
An elevated triglyceride-glucose index predicts adverse outcomes and interacts with the treatment strategy in patients with three-vessel disease
Insulin resistance is a pivotal risk factor for cardiovascular diseases, and the triglyceride-glucose (TyG) index is a wel...
Temporal relationship between triglyceride-glucose index and blood pressure and their joint cumulative effect on cardiovascular disease risk: a longitudinal cohort study
Temporal relationship between triglyceride-glucose index and blood pressure and their joint cumulative effect on cardiovascular disease risk: a longitudinal cohort study
Concurrent insulin resistance and elevated blood pressure are commonly observed in cardiovascular disease (CVD) and have l...
Cost-effectiveness of screening of coronary artery disease in patients with type 2 diabetes at a very high cardiovascular risk (SCADIAB) study. Updated study design: emulation of a randomised target trial using electronic health records
Cost-effectiveness of screening of coronary artery disease in patients with type 2 diabetes at a very high cardiovascular risk (SCADIAB) study. Updated study design: emulation of a randomised target trial using electronic health records
Type 2 diabetes mellitus (T2DM) is a substantial health problem with a high clinical and economic burden [1, 2]. Despite a...
Effects of dapagliflozin and dapagliflozin-saxagliptin on erythropoiesis, iron and inflammation markers in patients with type 2 diabetes and chronic kidney disease: data from the DELIGHT trial
Effects of dapagliflozin and dapagliflozin-saxagliptin on erythropoiesis, iron and inflammation markers in patients with type 2 diabetes and chronic kidney disease: data from the DELIGHT trial
This post-hoc analysis of the DELIGHT trial assessed effects of the SGLT2 inhibitor dapagliflozin on iron metabolism and m...
Cost-effectiveness of finerenone in chronic kidney disease associated with type 2 diabetes in The Netherlands
Cost-effectiveness of finerenone in chronic kidney disease associated with type 2 diabetes in The Netherlands
In the Netherlands, more than one million patients have type 2 diabetes (T2D), and approximately 36% of these patients hav...
Safety and efficacy of bempedoic acid: a systematic review and meta-analysis of randomised controlled trials
Safety and efficacy of bempedoic acid: a systematic review and meta-analysis of randomised controlled trials
Bempedoic Acid (BA) is a novel Lipid-Lowering Therapy (LLT). We performed a systematic review and meta-analysis to assess ...
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