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CircBUB1 activates the PI3K/AKT signaling pathway to promote the migration and invasion of glioblastoma cells
CircBUB1 activates the PI3K/AKT signaling pathway to promote the migration and invasion of glioblastoma cells
Glioblastoma (GBM), the most prevalent primary malignant brain tumor in adults, is characterized by aggressive and invasiv...
Effects of somatostatin, a somatostatin agonist, and an antagonist, on a putative migraine trigger pathway
Effects of somatostatin, a somatostatin agonist, and an antagonist, on a putative migraine trigger pathway
KeywordsCerebral cortexCortical spreading depressionFlashing lightMigraineNucleus raphe magnusPeriaqueductal gray matterSo...
Immunohistochemical determination of the excitatory and inhibitory axonal endings contacting NUCB2/nesfatin-1 neurons
Immunohistochemical determination of the excitatory and inhibitory axonal endings contacting NUCB2/nesfatin-1 neurons
Nesfatin-1 is an anorexigenic peptide suppressing food intake and is synthesized and secreted by neurons located in the hy...
Peripheral administration of lipidized NPAF and NPFF analogs does not influence central food intake regulation but induces anxiety-like behavior
Peripheral administration of lipidized NPAF and NPFF analogs does not influence central food intake regulation but induces anxiety-like behavior
RF-amide peptides influence multiple physiological processes, including the regulation of appetite, stress responses, beha...
Illuminating the neuropeptide Y4 receptor and its ligand pancreatic polypeptide from a structural, functional, and therapeutic perspective
Illuminating the neuropeptide Y4 receptor and its ligand pancreatic polypeptide from a structural, functional, and therapeutic perspective
The neuropeptide Y4 receptor (Y4R), a rhodopsin-like G protein-coupled receptor (GPCR) and the hormone pancreatic polypept...
Cyclooxygenase-2 inhibition affects the ratio of GluN2A/GluN2B receptor subunits through interaction with mGluR5 in the mouse brain
Cyclooxygenase-2 inhibition affects the ratio of GluN2A/GluN2B receptor subunits through interaction with mGluR5 in the mouse brain
One of the leading hypotheses of depression suggests that its pathomechanism is associated with over-activation of N-methy...
A comparative study on the effects of human serum albumin and α-melanocyte-stimulating hormone fusion proteins on the anti-neuroinflammatory in the central nervous system of adult mice
A comparative study on the effects of human serum albumin and α-melanocyte-stimulating hormone fusion proteins on the anti-neuroinflammatory in the central nervous system of adult mice
α-MSH, as an endogenous neuropeptide (Fetissov et al., 2019; Hidese et al., 2023), regulates nuclear factor kappa-B (NF-κB...
The role of NPY signaling pathway in diagnosis, prognosis and treatment of stroke
The role of NPY signaling pathway in diagnosis, prognosis and treatment of stroke
Stroke is currently the second most prominent cause of mortality worldwide, contributing to a substantial burden of diseas...
Measurement of neuropeptide Y with molecularly imprinted polypyrrole on carbon fiber microelectrodes
Measurement of neuropeptide Y with molecularly imprinted polypyrrole on carbon fiber microelectrodes
Neuropeptides are related to many processes of human life, from hormones that carry chemical signals into the endocrine sy...
Localization of truncated TrkB and co-expression with full-length TrkB in the cerebral cortex of adult mice
Localization of truncated TrkB and co-expression with full-length TrkB in the cerebral cortex of adult mice
In the mammalian brain, many bioactive molecules function, and their expressions are spatiotemporally regulated. Among the...
Perioperative changes of serum orphanin in diabetic patients and its relationship with sympathetic nervous system
Perioperative changes of serum orphanin in diabetic patients and its relationship with sympathetic nervous system
Diabetes is the disease with the highest incidence in the world except coronary heart disease and hypertension, which pose...
A recent update on drugs and alternative approaches for parkinsonism
A recent update on drugs and alternative approaches for parkinsonism
Neurodegenerative disorders are probably the most prevalent form of condition nowadays. Neurodegenerative disorders are di...
Effect of valproic acid combined with transplantation of olfactory ensheathing cells modified by neurotrophic 3 gene on nerve protection and repair after traumatic brain injury
Effect of valproic acid combined with transplantation of olfactory ensheathing cells modified by neurotrophic 3 gene on nerve protection and repair after traumatic brain injury
KeywordsTraumatic brain injuryValproic acidNeurotrophic 3 geneOlfactory ensheathing cellsAbbreviationsTBITraumatic brain i...
New fraternine analogues: Evaluation of the antiparkinsonian effect in the model of Parkinson's disease
New fraternine analogues: Evaluation of the antiparkinsonian effect in the model of Parkinson's disease
Parkinson's disease (PD) is the second most common neurodegenerative disorder and its main pathological feature is the deg...
Cross talk about the role of Neuropeptide Y in CNS disorders and diseases
Cross talk about the role of Neuropeptide Y in CNS disorders and diseases
The nervous system is typically separated into the peripheral and central nervous systems (CNS), the latter of which is ma...
The use of intranasal oxytocin in the treatment of eating disorders
The use of intranasal oxytocin in the treatment of eating disorders
Eating disorders are often chronic and relapsing disorders, and AN has the highest death rate of any psychiatric disorder....
CDNF overexpression prevents motor-cognitive dysfunction by intrastriatal CPP-based delivery system in a Parkinson's disease animal model
CDNF overexpression prevents motor-cognitive dysfunction by intrastriatal CPP-based delivery system in a Parkinson's disease animal model
Neurodegenerative diseases, including Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS), and Parkinson's disea...
Neuroprotective effect of the PACAP-ADNP axis on SOD1G93A mutant motor neuron death induced by trophic factors deprivation
Neuroprotective effect of the PACAP-ADNP axis on SOD1G93A mutant motor neuron death induced by trophic factors deprivation
Amyotrophic lateral Sclerosis (ALS) is a neurodegenerative disease characterized by progressive degeneration of motor neur...
Improvement of actin dynamics and cognitive impairment in diabetes through troxerutin-mediated downregulation of TRPM7/CaN/cofilin
Improvement of actin dynamics and cognitive impairment in diabetes through troxerutin-mediated downregulation of TRPM7/CaN/cofilin
Numerous studies have reported an increased risk of cognitive impairment, known as “diabetes-related cognitive impairment”...
Neonatal oxytocin treatment alters levels of precursor and mature BDNF forms and modifies the expression of neuronal markers in the male rat hippocampus
Neonatal oxytocin treatment alters levels of precursor and mature BDNF forms and modifies the expression of neuronal markers in the male rat hippocampus
Neurogenesis and synaptogenesis during the early stages of development are profoundly influenced by the action of neurotro...
Dissecting the functional significance of HSP90AB1 and other heat shock proteins in countering glioblastomas and ependymomas using omics analysis and drug prediction using virtual screening
Dissecting the functional significance of HSP90AB1 and other heat shock proteins in countering glioblastomas and ependymomas using omics analysis and drug prediction using virtual screening
Heat shock proteins (HSPs) also known as stress proteins are an important class of proteins that are activated by the cell...
The regulatory effects of the apelin/APJ system on depression: A prospective therapeutic target
The regulatory effects of the apelin/APJ system on depression: A prospective therapeutic target
Available online 11 September 2023, 102382Author links open overlay panel, , , , , , AbstractDepression is a debilitating ...
Mate calling alters expression of neuropeptide, cocaine- and amphetamine- regulated transcript (CART) in the brain of male frog Microhyla nilphamariensis
Mate calling alters expression of neuropeptide, cocaine- and amphetamine- regulated transcript (CART) in the brain of male frog Microhyla nilphamariensis
Croaking in amphibians is an adaptive behaviour directed at enhancing mating success. To attract receptive females, males ...
Reduced mastication during growth inhibits cognitive function by affecting trigeminal ganglia and modulating Wnt signaling pathway and ARHGAP33 molecular transmission
Reduced mastication during growth inhibits cognitive function by affecting trigeminal ganglia and modulating Wnt signaling pathway and ARHGAP33 molecular transmission
Binding of brain-derived neurotrophic factor (BDNF) to its receptor tyrosine kinase B (TrkB) is essential for the developm...
An inclusive study of recent advancements in Alzheimer's disease: A comprehensive review
An inclusive study of recent advancements in Alzheimer's disease: A comprehensive review
Alzheimer's disease (AD) has emerged as one of the most serious ailments affecting the modern world. The rapid advancement...
Bee venom ameliorates oxidative stress and histopathological changes of hippocampus, liver and testis during status epileptics
Epilepsy in association with other dementias e.g., multiple sclerosis (MS), Alzheimer's disease (AD), Parkinson's disease ...
FGF-18 alleviates memory impairments and neuropathological changes in a rat model of Alzheimer's disease
Alzheimer's disease (AD) is the most common age-related neurodegenerative disorder marked by progressive loss of cognitive...
Effects of voluntary, and forced exercises on neurotrophic factors and cognitive function in animal models of Parkinson's disease
Parkinson's disease (PD) is one of the most common diseases of old age in the world, which occurs due to the destruction o...
Protective effects of Zishen Huoxue recipe against neuronal injury in the neurovascular unit of rats with vascular dementia by interfering with inflammatory cascade-induced pyroptosis
Vascular dementia (VD) is construed as a progressive disorder resulting from reduced cerebral blood flow and it severely i...
Neurobiochemical characteristics of arginine-rich peptides explain their potential therapeutic efficacy in neurodegenerative diseases
The damage, degeneration, or death of neurons depending on different areas of the brain causes a variety of incurable and ...
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