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Biochemical Clusters as Substitutes of Bone Biopsies in Kidney Transplant Patients
Biochemical Clusters as Substitutes of Bone Biopsies in Kidney Transplant Patients
Bone and mineral metabolism abnormalities are frequent in kidney transplant recipients and have been associated with cardi...
Changes in Blood Pressure is Associated with Bone Loss in US Adults: A Cross-Sectional Study from NHANES 2005–2018
Changes in Blood Pressure is Associated with Bone Loss in US Adults: A Cross-Sectional Study from NHANES 2005–2018
Hypertension and osteoporosis are common geriatric diseases, sharing similar risk factors. This study aims to investigate ...
Identification of a Novel Homozygous Missense Mutation in the CLDN16 Gene to Decipher the Ambiguous Clinical Presentation Associated with Autosomal Dominant Hypocalcaemia and Familial Hypomagnesemia with Hypercalciuria and Nephrocalcinosis in an Indian Family
Identification of a Novel Homozygous Missense Mutation in the CLDN16 Gene to Decipher the Ambiguous Clinical Presentation Associated with Autosomal Dominant Hypocalcaemia and Familial Hypomagnesemia with Hypercalciuria and Nephrocalcinosis in an Indian Family
Familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHNNC) is a rare autosomal recessive renal tubulopathy d...
Effect of Roflumilast, a Selective PDE4 Inhibitor, on Bone Phenotypes in ADO2 Mice
Effect of Roflumilast, a Selective PDE4 Inhibitor, on Bone Phenotypes in ADO2 Mice
Autosomal Dominant Osteopetrosis type II (ADO2) is a rare bone disease of impaired osteoclastic bone resorption that usual...
Osteosarcopenia: Prevalence and 10-Year Fracture and Mortality Risk – A Longitudinal, Population-Based Study of 75-Year-Old Women
Osteosarcopenia: Prevalence and 10-Year Fracture and Mortality Risk – A Longitudinal, Population-Based Study of 75-Year-Old Women
Osteosarcopenia is the coexistence of low bone mass and sarcopenia. In older women, its prevalence is not well described, ...
Comparison of the Clinical Outcomes of Vesselplasty vs. Percutaneous Vertebroplasty for the Treatment of Neurologically Intact Osteoporotic Kümmell’s Disease: A Retrospective Study
Comparison of the Clinical Outcomes of Vesselplasty vs. Percutaneous Vertebroplasty for the Treatment of Neurologically Intact Osteoporotic Kümmell’s Disease: A Retrospective Study
Kummell’s disease (KD) is a rare clinical complication of osteoporotic vertebral compression fractures (OVCFs). Mini...
The Effect of Rheumatoid Arthritis on Features Associated with Sarcopenia: A Mendelian Randomization Study
The Effect of Rheumatoid Arthritis on Features Associated with Sarcopenia: A Mendelian Randomization Study
Previous epidemiological evidence suggests rheumatoid arthritis is associated with sarcopenia-related features. However, m...
Regulatory Pathways in Growth Plate Chondrocytes that Are Impacted by Matrix Vesicle microRNA Identified by Targeted RISC Pulldown and Sequencing of the Resulting Transcriptome
Regulatory Pathways in Growth Plate Chondrocytes that Are Impacted by Matrix Vesicle microRNA Identified by Targeted RISC Pulldown and Sequencing of the Resulting Transcriptome
During endochondral bone formation, growth plate chondrocytes are differentially regulated by various factors and hormones...
Trend and Seasonality of Hip Fractures in Catalonia, Spain: Exploring the Influence of Climate
Trend and Seasonality of Hip Fractures in Catalonia, Spain: Exploring the Influence of Climate
To describe the secular trend and seasonality of the incidence of hip fracture (HF) and its relationship with climatic var...
Lipid Metabolism, Methylation Aberrant, and Osteoporosis: A Multi-omics Study Based on Mendelian Randomization
Lipid Metabolism, Methylation Aberrant, and Osteoporosis: A Multi-omics Study Based on Mendelian Randomization
Observational studies have shown a causal association between dyslipidemia and osteoporosis, but the genetic causation and...
An Additional Lrp4 High Bone Mass Mutation Mitigates the Sost-Knockout Phenotype in Mice by Increasing Bone Remodeling
An Additional Lrp4 High Bone Mass Mutation Mitigates the Sost-Knockout Phenotype in Mice by Increasing Bone Remodeling
Pathogenic variants disrupting the binding between sclerostin (encoded by SOST) and its receptor LRP4 have previously been...
The Association Between SHBG and Osteoporosis: A NHANES Cross-Sectional Study and A Bidirectional Mendelian Randomization
The Association Between SHBG and Osteoporosis: A NHANES Cross-Sectional Study and A Bidirectional Mendelian Randomization
This study aimed to examine the association between sex hormone-binding globulin (SHBG) and osteoporosis through a cross-s...
Coenzyme Q10 Protects Against Hyperlipidemia-Induced Osteoporosis by Improving Mitochondrial Function via Modulating miR-130b-3p/PGC-1α Pathway
Coenzyme Q10 Protects Against Hyperlipidemia-Induced Osteoporosis by Improving Mitochondrial Function via Modulating miR-130b-3p/PGC-1α Pathway
In hyperlipidemia-induced osteoporosis, bone marrow mesenchymal stem cells (BMSCs) differentiate into more adipocytes than...
A Critical Review of Current Worldwide Definitions of Sarcopenia
A Critical Review of Current Worldwide Definitions of Sarcopenia
With the increasing number of elderly individuals worldwide, the prevalence of age-related loss of muscle mass, referred t...
PLS3 Mutations in X-Linked Osteoporosis: Clinical and Genetic Features in Five New Families
PLS3 Mutations in X-Linked Osteoporosis: Clinical and Genetic Features in Five New Families
Childhood-onset osteoporosis is a rare but clinically significant condition. Studies have shown pathogenic variants in mor...
Genetic, Immunological, Dietary, Gut Microbiota, and Environmental Determinants of Osteoporosis in the Course of Celiac Disease: Which Factor Plays the First Violin in This Orchestra?
Genetic, Immunological, Dietary, Gut Microbiota, and Environmental Determinants of Osteoporosis in the Course of Celiac Disease: Which Factor Plays the First Violin in This Orchestra?
Celiac disease (CD) is a chronic small intestinal immune-mediated enteropathy precipitated by exposure to dietary gluten i...
Nutrition Interventions on Muscle-Related Components of Sarcopenia in Females: A Systematic Review of Randomized Controlled Trials
Nutrition Interventions on Muscle-Related Components of Sarcopenia in Females: A Systematic Review of Randomized Controlled Trials
Sarcopenia is a skeletal muscle disease categorized by low muscle strength, muscle quantity or quality, and physical perfo...
Narrative Review of Effects of Glucagon-Like Peptide-1 Receptor Agonists on Bone Health in People Living with Obesity
Narrative Review of Effects of Glucagon-Like Peptide-1 Receptor Agonists on Bone Health in People Living with Obesity
Glucagon-like peptide-1 Receptor agonists (GLP-1Ras) such as liraglutide and semaglutide have been recently approved as me...
The Relationship Between Scoliosis, Spinal Bone Density, and Truncal Muscle Strength in Familial Dysautonomia Patients
The Relationship Between Scoliosis, Spinal Bone Density, and Truncal Muscle Strength in Familial Dysautonomia Patients
This combined retrospective and prospective study aimed to investigate the relationship between scoliosis, spinal bone min...
Management of Osteoporosis, Fracture and Falls in People with Multiple Sclerosis: Systematic Review of Guidelines
Management of Osteoporosis, Fracture and Falls in People with Multiple Sclerosis: Systematic Review of Guidelines
People with multiple sclerosis (MS) have a higher prevalence of osteoporosis, falls and fractures. Guidelines for MS popul...
Microarchitecture Alternations of Osteochondral Junction in Patients with Osteonecrosis of the Femoral Head
Microarchitecture Alternations of Osteochondral Junction in Patients with Osteonecrosis of the Femoral Head
The study was aimed to investigate microarchitecture of osteochondral junction in patients with osteonecrosis of the femor...
Hereditary Hypophosphatemic Rickets with Hypercalciuria Presenting with Enthesopathy, Renal Cysts, and High Serum c-Terminal FGF23: Single-Center Experience and Systematic Review
Hereditary Hypophosphatemic Rickets with Hypercalciuria Presenting with Enthesopathy, Renal Cysts, and High Serum c-Terminal FGF23: Single-Center Experience and Systematic Review
Hereditary hypophosphatemic rickets with hypercalciuria (HHRH) is a rare disorder of phosphate homeostasis. We describe a ...
Treatment Effect of Zoledronic Acid in Chronic Non-bacterial Osteomyelitis of the Jaw: A Case Series
Treatment Effect of Zoledronic Acid in Chronic Non-bacterial Osteomyelitis of the Jaw: A Case Series
Chronic non-bacterial osteomyelitis (CNO) is an autoinflammatory, osteolytic bone disorder sometimes localized to a unifoc...
Epidemiology of Tumor-Induced Osteomalacia in Germany Based on Real World Data
Epidemiology of Tumor-Induced Osteomalacia in Germany Based on Real World Data
Tumor-induced osteomalacia (TIO) is an ultra-rare disease caused mostly by benign tumors that secrete fibroblast growth fa...
Intervertebral Disk Degeneration and Bone Mineral Density: A Bidirectional Mendelian Randomization Study
Intervertebral Disk Degeneration and Bone Mineral Density: A Bidirectional Mendelian Randomization Study
This study aimed to investigate the causal relationship between bone mineral density (BMD) and intervertebral disk degener...
Identification of Key Osteoporosis Genes Through Comparative Analysis of Men's and Women's Osteoblast Transcriptomes
Identification of Key Osteoporosis Genes Through Comparative Analysis of Men's and Women's Osteoblast Transcriptomes
Osteoporosis disproportionately affects older women, yet gender differences in human osteoblasts remain unexplored. Identi...
Comparison of Motion Grading in 1,000 Patients by First- and Second-Generation HR-pQCT: A Propensity Score Matched Cohort Study
Comparison of Motion Grading in 1,000 Patients by First- and Second-Generation HR-pQCT: A Propensity Score Matched Cohort Study
In-vivo bone microstructure measured by high-resolution peripheral quantitative computed tomography (HR-pQCT) is gaining i...
Pilot Study: Short Term Impact of Radiation Therapy on Bone Mineral Density and Bone Metabolism
Pilot Study: Short Term Impact of Radiation Therapy on Bone Mineral Density and Bone Metabolism
Despite the risk of complications, high dose radiation therapy is increasingly utilized in the management of selected bone...
The Interconnection Between Muscle and Bone: A Common Clinical Management Pathway
The Interconnection Between Muscle and Bone: A Common Clinical Management Pathway
Often observed with aging, the loss of skeletal muscle (sarcopenia) and bone (osteoporosis) mass, strength, and quality, i...
Mitophagy Activation by Urolithin A to Target Muscle Aging
Mitophagy Activation by Urolithin A to Target Muscle Aging
The age-related loss of skeletal muscle function starts from midlife and if left unaddressed can lead to an impaired quali...
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