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An objective way to predict remission and relapse in Cushing disease using Bayes’ theorem of probability
An objective way to predict remission and relapse in Cushing disease using Bayes’ theorem of probability
In this study on patients with Cushing disease, post-transsphenoidal surgery (TSS), we attempt to predict the probability ...
Development of diagnostic algorithm for Cushing’s syndrome: a tertiary centre experience
Development of diagnostic algorithm for Cushing’s syndrome: a tertiary centre experience
No consensus exists as the gold standard for Cushing’s Syndrome (CS) screening. This study aimed to evaluate the dia...
Endocrine disruptors, aryl hydrocarbon receptor and cortisol secretion
Endocrine disruptors, aryl hydrocarbon receptor and cortisol secretion
Endocrine disruptors exert a plethora of effects in endocrine tissues, from altered function to carcinogenesis. Given its ...
Authorship of Italian medical literature on neuroendocrine neoplasms: any gender gap?
Authorship of Italian medical literature on neuroendocrine neoplasms: any gender gap?
While males have dominated the physician lines over the last decades the recent female doctors’ number increasing mi...
JPT2 in subclinical hypothyroidism-related miscarriage as a transcription co-factor: involvement of LEPR/STAT3 activation
JPT2 in subclinical hypothyroidism-related miscarriage as a transcription co-factor: involvement of LEPR/STAT3 activation
Subclinical hypothyroidism (SCH) has been identified to be associated with implantation failure, in which the dysfunction ...
Rachel score: a nomogram model for predicting the prognosis of lung neuroendocrine tumors
Rachel score: a nomogram model for predicting the prognosis of lung neuroendocrine tumors
Lung NET, classified in typical carcinoids (TC) and atypical carcinoids (AC), are highly heterogeneous in their biology an...
The need for the GREAT+ score to predict relapse in Graves’ disease: a questionnaire among patients and internal medicine specialists
The need for the GREAT+ score to predict relapse in Graves’ disease: a questionnaire among patients and internal medicine specialists
Graves’ disease (GD) is an auto-immune cause of hyperthyroidism. First-line treatment often consists of a 12–1...
Sodium-glucose cotransporter 2 inhibitors and cancer: a systematic review and meta-analysis
Sodium-glucose cotransporter 2 inhibitors and cancer: a systematic review and meta-analysis
The effect of sodium–glucose cotransporter 2 (SGLT2) inhibitors on cancer has yet to be fully elucidated. This syste...
Development of a diagnostic model for pre-washout screening of primary aldosteronism
Development of a diagnostic model for pre-washout screening of primary aldosteronism
Primary aldosteronism (PA) diagnosis is affected by antihypertensive drugs that are commonly taken by patients with suspec...
Endocrinology application of molecular imaging: current role of PET/CT
Endocrinology application of molecular imaging: current role of PET/CT
In recent years, nuclear medicine imaging methods have proven to be of paramount importance in a wide variety of diseases,...
Evaluation of pituitary function and metabolic parameters in patients with traumatic maxillofacial fractures
Evaluation of pituitary function and metabolic parameters in patients with traumatic maxillofacial fractures
This study was designed to assess the pituitary functions of patients with traumatic maxillofacial fractures and compare t...
Mouse model of Graves’ orbitopathy induced by the immunization with TSHR A and IGF-1R α subunit gene
Mouse model of Graves’ orbitopathy induced by the immunization with TSHR A and IGF-1R α subunit gene
The study aimed to establish a mouse model of Graves’ disease (GD) with Graves’ orbitopathy (GO; GD +...
Sculptures with goiter in the Ossuccio Sacred Mount: when pathognomonic signs have a specific moral significance
Sculptures with goiter in the Ossuccio Sacred Mount: when pathognomonic signs have a specific moral significance
Conflict of interest The authors declare no competing inter...
Increased risk of erythrocytosis in men with type 2 diabetes treated with combined sodium-glucose cotransporter-2 inhibitor and testosterone replacement therapy
Increased risk of erythrocytosis in men with type 2 diabetes treated with combined sodium-glucose cotransporter-2 inhibitor and testosterone replacement therapy
In clinical trials, sodium-glucose cotransporter-2 inhibitors (SGLT-2i) and testosterone replacement therapy (TRT) were sh...
Metabolomic profiles of ovariectomized mice and their associations with body composition and frailty-related parameters in postmenopausal women
Metabolomic profiles of ovariectomized mice and their associations with body composition and frailty-related parameters in postmenopausal women
Menopause, a dramatical estrogen-deficient condition, is considered the most significant milestone in women’s health...
Analysis of the finasteride treatment and its withdrawal in the rat hypothalamus and hippocampus at whole-transcriptome level
Analysis of the finasteride treatment and its withdrawal in the rat hypothalamus and hippocampus at whole-transcriptome level
As reported in patients treated for androgenetic alopecia with finasteride (i.e., a blocker of the enzyme 5 alpha...
Regulation of iodine-glucose flip-flop in SW1736 anaplastic thyroid cancer cell line
Regulation of iodine-glucose flip-flop in SW1736 anaplastic thyroid cancer cell line
The alternative manner of iodide and glucose uptake found in different types of thyroid cancer, referred to flip-flop. ATC...
Targeted therapy in BRAF mutated aggressive papillary craniopharyngioma: a case report and overview of the literature
Targeted therapy in BRAF mutated aggressive papillary craniopharyngioma: a case report and overview of the literature
Papillary craniopharyngiomas harbor the BRAF V600E mutation, which paves the way for using BRAF inhibitor molecules to tre...
Improvement in clinical features of hypercortisolism during osilodrostat treatment: findings from the Phase III LINC 3 trial in Cushing's disease
Improvement in clinical features of hypercortisolism during osilodrostat treatment: findings from the Phase III LINC 3 trial in Cushing's disease
Cushing’s disease is associated with substantial morbidity and impaired quality of life (QoL) resulting from excess ...
FBXO28 reduces high-fat diet-induced hyperlipidemia in mice by alleviating abnormal lipid metabolism and inflammatory responses
FBXO28 reduces high-fat diet-induced hyperlipidemia in mice by alleviating abnormal lipid metabolism and inflammatory responses
Hyperlipidemia is a lipid metabolism disorder with increasing incidence and prevalence worldwide. Abnormal lipid metabolis...
A very-low-calorie ketogenic diet normalises obesity-related enhanced levels of erythropoietin compared with a low-calorie diet or bariatric surgery
A very-low-calorie ketogenic diet normalises obesity-related enhanced levels of erythropoietin compared with a low-calorie diet or bariatric surgery
Nutritional ketosis synergistically with body-weight loss induced by a very-low-calorie ketogenic diet (VLCKD) has proven ...
The use of telecytology for the evaluation of thyroid nodules fine-needle aspiration biopsy specimens: a systematic review
The use of telecytology for the evaluation of thyroid nodules fine-needle aspiration biopsy specimens: a systematic review
Fine needle aspiration biopsy (FNAB) is currently the gold standard for diagnosis and treatment of thyroid nodules, but th...
Quantitative ultrasound techniques and biochemical markers to assess liver steatosis and fibrosis in newly diagnosed acromegaly
Quantitative ultrasound techniques and biochemical markers to assess liver steatosis and fibrosis in newly diagnosed acromegaly
The liver is known to be protected from steatosis under the influence of high GH/IGF-1. Cytokeratin 18 (CK18) and insulin-...
Sex and disease severity-based analysis of steroid hormones in ME/CFS
Sex and disease severity-based analysis of steroid hormones in ME/CFS
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disease characterized by persistent fatigue ...
Association of serum 25-hydroxyvitamin D with cardiovascular mortality and kidney outcome in patients with early stages of CKD
Association of serum 25-hydroxyvitamin D with cardiovascular mortality and kidney outcome in patients with early stages of CKD
While serum 25-hydroxyvitamin D (25[OH]D) deficiency is prevalent in chronic kidney disease (CKD), the effects of 25(OH)D ...
Correlation of serum DKK1 level with skeletal phenotype in children with osteogenesis imperfecta
Correlation of serum DKK1 level with skeletal phenotype in children with osteogenesis imperfecta
We aim to detect serum DKK1 level of pediatric patients with OI and to analyze its relationship with the genotype and phen...
HYPOXIA induces lncRNA HOTAIR for recruiting RELA in papillary thyroid cancer cells to upregulate miR-181a and promote angiogenesis
HYPOXIA induces lncRNA HOTAIR for recruiting RELA in papillary thyroid cancer cells to upregulate miR-181a and promote angiogenesis
Papillary thyroid carcinoma (PTC) is one of the most common subtypes of thyroid carcinoma. Exosomal miR-181a plays an impo...
Germline polymorphisms of the NOD2 pathway may predict the effectiveness of radioiodine in differentiated thyroid cancer treatment
Germline polymorphisms of the NOD2 pathway may predict the effectiveness of radioiodine in differentiated thyroid cancer treatment
Differentiated thyroid cancer (DTC) presents a complex clinical challenge, especially in patients with distant metastases ...
TFCP2L1, a potential differentiation regulator, predicts favorable prognosis and dampens thyroid cancer progression
TFCP2L1, a potential differentiation regulator, predicts favorable prognosis and dampens thyroid cancer progression
Thyroid cancer has an overwhelming incidence in the population. Thus, there is an urgent need to understand the underlying...
The complexity of glucose time series is associated with short- and long-term mortality in critically ill adults: a multi-center, prospective, observational study
The complexity of glucose time series is associated with short- and long-term mortality in critically ill adults: a multi-center, prospective, observational study
The wealth of data taken from continuous glucose monitoring (CGM) remains to be fully used. We aimed to evaluate the relat...
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