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Regulation of hepatic fibrosis by carcinoembryonic antigen-related cell adhesion molecule 1
Buzzetti E. Pinzani M. Tsochatzis E.A. The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD).Metaboli...
The IL-8-CXCR1/2 axis contributes to diabetic kidney disease
International Center for T1D, Centro di Ricerca Pediatrica Romeo ed Enrica Invernizzi, Dipartimento di Scienze Biomediche ...
Molecular mechanisms underlying hepatitis C virus infection-related diabetes
Antonelli A. Ferrari S.M. Giuggioli D. et al.Hepatitis C virus infection and type 1 and type 2 diabetes mellitus [J].World...
Lipids activate skeletal muscle mitochondrial fission and quality control networks to induce insulin resistance in humans
Samuel V.T. Petersen K.F. Shulman G.I. Lipid-induced insulin resistance: unravelling the mechanism.Lancet. 375: 2267-2277Y...
Four-and-a-half LIM domain protein 2 (FHL2) deficiency protects mice from diet-induced obesity and high FHL2 expression marks human obesity
AbstractObjectiveFour-and-a-Half-LIM-domain-protein 2 (FHL2) modulates multiple signal transduction pathways but has not b...
Diabetes and COVID-19: The past, the present, and the future
Saeedi P. Petersohn I. Salpea P. Malanda B. Karuranga S. Unwin N. et al.Global and regional diabetes prevalence estimates ...
Exosomes: advances, development and potential therapeutic strategies in diabetic nephropathy
Webster A.C. Nagler E.V. Morton R.L. Masson P. Chronic kidney disease.Lancet. 389: 1238-1252https://doi.org/10.1016/s0140-...
Suppressor of cytokine signalling-2 controls hepatic gluconeogenesis and hyperglycemia by modulating JAK2/STAT5 Signalling pathway
Footnotes1 These authors contributed equally to this work.AffiliationsThe Key Laboratory of Rare Metabolic Diseases, The K...
Non-glucose modulators of insulin secretion in healthy humans: (dis)similarities between islet and in vivo studies
Henquin JC. Glucose-induced insulin secretion in isolated human islets: Does it truly reflect β-cell function in vivo? Mol...
Obesity and COVID-19 mortality
KeywordsConflicts of interest: All authors report that they have no potential conflicts of interest.Acknowledgements: We w...
Thiazolidinediones, alpha-glucosidase inhibitors, meglitinides, sulfonylureas, and hepatocellular carcinoma risk: A meta-analysis
Balogh J. Victor D. Asham E.H. et al.Hepatocellular carcinoma: a review.J Hepatocell Carcinoma. 3: 41-53Simon T.G. King L....
The progression and regression of metabolic dysfunction-associated fatty liver disease are associated with the development of subclinical atherosclerosis: A prospective analysis
Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, S...
A longitudinal analysis of arterial stiffness and wave reflection in preeclampsia: Identification of changepoints
Division of Experimental Medicine, Department of Medicine, McGill University, 1001 Décarie Boulevard, Montreal, Quebec H4A...
A new mechanism of obeticholic acid on NASH treatment by inhibiting NLRP3 inflammasome activation in macrophage
Objective Obeticholic acid (OCA) has been proved to play potential therapeutic effect on nonalcoholic ...
Diabetes and kidney disease: emphasis on treatment with SGLT-2 inhibitors and GLP-1 receptor agonists
Chronic kidney disease.Lancet. 379: 165-180Bjerg L. Hulman A. Carstensen B. Charles M. Jørgensen M.E. Witte D.R. Developme...
Downregulation of NK cell activities in Apolipoprotein C-III-induced hyperlipidemia resulting from lipid-induced metabolic reprogramming and crosstalk with lipid-laden dendritic cells
Department of Basic Medicine, School of Medicine, Yangzhou University, Yangzhou 225001, ChinaDepartment of Gastroenterolog...
Circulating α-klotho regulates metabolism via distinct central and peripheral mechanisms
Kuro-o M. Nabeshima Y. Matsumura Y. Aizawa H. Kawaguchi H. Suga T. et al.Mutation of the mouse klotho gene leads to a synd...
Irisin in nonalcoholic fatty liver disease: need for an updated meta-analysis
Polyzos S.A. Kountouras J. Anastasilakis A.D. Geladari E.V. Mantzoros C.S. Irisin in patients with nonalcoholic fatty live...
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