Wong GW, Wang J, Hug C, Tsao TS, Lodish HF. A family of Acrp30/adiponectin structural and functional paralogs. Proc Natl Acad Sci U S A. 2004;101:1023.

Article  Google Scholar 

Liu M, Liu F. Regulation of adiponectin multimerization, signaling and function. Best Pract Res Clin Endocrinol Metab. 2014;28:25.

Article  PubMed  Google Scholar 

Waki H, Yamauchi T, Kamon J, Kita S, Ito Y, Hada Y, et al. Generation of globular fragment of adiponectin by leukocyte elastase secreted by monocytic cell line THP-1. Endocrinology. 2005;146:790.

Article  PubMed  CAS  Google Scholar 

Wolf AM, Wolf D, Avila MA, Moschen AR, Berasain C, Enrich B, et al. Up-regulation of the anti-inflammatory adipokine adiponectin in acute liver failure in mice. J Hepatol. 2006;44:537.

Article  PubMed  CAS  Google Scholar 

Lin T, Qiu Y, Liu Y, Mohan R, Li Q, Lei B. Expression of adiponectin and its receptors in type 1 diabetes mellitus in human and mouse retinas. Mol Vis. 2013;19:1.

CAS  Google Scholar 

Crawford LJA, Peake R, Price S, Morris TCM, Irvine AE. Adiponectin is produced by lymphocytes and is a negative regulator of granulopoiesis. J Leukoc Biol. 2010;88:807.

Article  PubMed  CAS  Google Scholar 

Miller M, Cho JY, Pham A, Ramsdell J, Broide DH. Adiponectin and Functional Adiponectin Receptor 1 Are Expressed by Airway Epithelial Cells in Chronic Obstructive Pulmonary Disease. J Immunol. 2009;182:684.

Article  PubMed  CAS  Google Scholar 

Katsiougiannis S, Kapsogeorgou EK, Manoussakis MN, Skopouli FN. Salivary gland epithelial cells: A new source of the immunoregulatory hormone adiponectin. Arthritis Rheum. 2006;54:1.

Article  Google Scholar 

Mao X, Kikani CK, Riojas RA, Langlais P, Wang L, Ramos FJ, et al. APPL1 binds to adiponectin receptors and mediates adiponectin signaling and function. Nat Cell Biol. 2006;8:516.

Article  PubMed  CAS  Google Scholar 

Zacharioudaki V, Androulidaki A, Arranz A, Vrentzos G, Margioris AN, Tsatsanis C. Adiponectin Promotes Endotoxin Tolerance in Macrophages by Inducing IRAK-M Expression. J Immunol. 2009;182:6444.

Article  PubMed  CAS  Google Scholar 

Wanninger J, Neumeier M, Weigert J, Bauer S, Weiss TS, Schäffler A, et al. Adiponectin-stimulated CXCL8 release in primary human hepatocytes is regulated by ERK1/ERK2, p38 MAPK, NF-κB, and STAT3 signaling pathways. Am J Physiol Gastrointest Liver Physiol. 2009;297:G611.

Article  PubMed  CAS  Google Scholar 

Lee MH, Klein RL, El-Shewy HM, Luttrell DK, Luttrell LM. The adiponectin receptors AdipoR1 and AdipoR2 activate ERK1/2 through a Src/Ras-dependent pathway and stimulate cell growth. Biochemistry. 2008;47:11682.

Article  PubMed  CAS  Google Scholar 

Antuna-Puente B, Feve B, Fellahi S, Bastard JP. Adipokines: The missing link between insulin resistance and obesity. Diabetes Metab. 2008;34:2.

Article  PubMed  CAS  Google Scholar 

Bastard JP, Maachi M, Lagathu C, Kim MJ, Caron M, Vidal H, et al. Recent advances in the relationship between obesity, inflammation, and insulin resistance. Eur Cytokine Netw. 2006;1:1.

Google Scholar 

Ricker LJAG, Kijlstra A, Kessels AGH, de Jager W, Hendrikse F, La Heij EC. Adipokine levels in subretinal fluid from patients with rhegmatogenous retinal detachment. Exp Eye Res. 2012;94:56.

Article  PubMed  CAS  Google Scholar 

Srinivasan V, Chidambaram S, Coral K, Rishi P, Sulochana KN. Measurement of adiponectin in vitreous and plasma of patients with proliferative diabetic retinopathy and its correlation with vascular endothelial growth factor, pigment epithelial derived factor and insulin like growth factor-1. Int J Pharma Bio Sci. 2013;4:1.

Google Scholar 

Costagliola C, Daniele A, dell’Omo R, Romano MR, Aceto F, Agnifili L, et al. Aqueous humor levels of vascular endothelial growth factor and adiponectin in patients with type 2 diabetes before and after intravitreal bevacizumab injection. Exp Eye Res. 2013;110:1.

Article  Google Scholar 

Mao D, Peng H, Li Q, Wang J, Li P, Hu K, et al. Aqueous humor and plasma adiponectin levels in proliferative diabetic retinopathy patients. Curr Eye Res. 2012;37:1.

Article  Google Scholar 

Srinivasan V, Karthikka P, Coral K, Chidambaram S, Rishi P, Sulochana KN. Expression and localisation of adiponectin and its receptors in human ocular tissues. Int J Pharma Bio Sci. 2014;5:1.

Google Scholar 

Hinton DR, He S, Jin ML, Barron E, Ryan SJ. Novel growth factors involved in the pathogenesis of proliferative vitreoretinopathy. Eye. 2002;16:1.

Article  Google Scholar 

Cui JZ, Chiu A, Maberley D, Ma P, Samad A, Matsubara JA. Stage specificity of novel growth factor expression during development of proliferative vitreoretinopathy. Eye. 2007;21:200.

Article  PubMed  CAS  Google Scholar 

Aiello LP, Bursell SE, Clermont A, Duh E, Ishii H, Takagi C, et al. Vascular endothelial growth factor-induced retinal permeability is mediated by protein kinase C in vivo and suppressed by an orally effective β-isoform-selective inhibitor. Diabetes. 1997;46:1473.

Article  PubMed  CAS  Google Scholar 

Witmer AN, Vrensen GFJM, Van Noorden CJF, Schlingemann RO. Vascular endothelial growth factors and angiogenesis in eye disease. Prog Retin Eye Res. 2003;22:1.

Article  PubMed  CAS  Google Scholar 

Gariano RF, Gardner TW. Retinal angiogenesis in development and disease. Nature. 2005;438:960.

Article  PubMed  CAS  Google Scholar 

Kuiper EJ, Van Nieuwenhoven FA, de Smet MD, van Meurs JC, Tanck MW, Oliver N, et al. The angio-fibrotic switch of VEGF and CTGF in proliferative diabetic retinopathy. PLoS One. 2008;3:e2675.

Article  PubMed  PubMed Central  Google Scholar 

Roy S, Amin S, Roy S. Retinal fibrosis in diabetic retinopathy. Exp Eye Res. 2016;142:71.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Chaudhary R, Scott RAH, Wallace G, Berry M, Logan A, Blanch RJ. Inflammatory and fibrogenic factors in proliferative vitreoretinopathy development. Transl Vis Sci Technol. 2020;9:23.

Article  PubMed  PubMed Central  Google Scholar 

Palanisamy K, Nareshkumar RN, Sivagurunathan S, Raman R, Sulochana KN, Chidambaram S. Anti-angiogenic effect of adiponectin in human primary microvascular and macrovascular endothelial cells. Microvasc Res. 2019;122:136.

Article  PubMed  CAS  Google Scholar 

Palanisamy K, Karunakaran C, Raman R, Chidambaram S. Optimization of an in vitro bilayer model for studying the functional interplay between human primary retinal pigment epithelial and choroidal endothelial cells isolated from donor eyes. BMC Res Notes. 2019;12:1.

Article  CAS  Google Scholar 

Ma X, Zhang H, Pan Q, Zhao Y, Chen J, Zhao B, et al. Hypoxia/aglycemia-induced endothelial barrier dysfunction and tight junction protein downregulation can be ameliorated by citicoline. PLoS One. 2013;8:e82604.

Article  PubMed  PubMed Central  Google Scholar 

Zheng H, Yang Z, Xin Z, Yang Y, Yu Y, Cui J, et al. Glycogen synthase kinase-3β: A promising candidate in the fight against fibrosis. Theranostics. 2020;10:11737.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Ziemke F, Mantzoros CS. Adiponectin in insulin resistance: Lessons from translational research. Am J Clin Nut. 2010;91:258S.

Article  CAS  Google Scholar 

Nishinaka A, Nakamura S, Tanaka M, Masuda T, Inoue Y, Yamamoto T, et al. Excess adiponectin in eyes with progressive ocular vascular diseases. FASEB J. 2021;35:2.

Article  Google Scholar 

Ouchi N, Kobayashi H, Kihara S, Kumada M, Sato K, Inoue T, et al. Adiponectin Stimulates Angiogenesis by Promoting Cross-talk between AMP-activated Protein Kinase and Akt Signaling in Endothelial Cells. J Biol Chem. 2004;279:1304.

Article  PubMed  CAS  Google Scholar 

Becker B, Kronenberg F, Kielstein JT, Haller H, Morath C, Ritz E, et al. Renal insulin resistance syndrome, adiponectin and cardiovascular events in patients with kidney disease: The mild and moderate kidney disease study. J Am Soc Nephrol. 2005;16:1097.