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Gaussian processes modeling for the prediction of polymeric nanoparticle formulation design to enhance encapsulation efficiency and therapeutic efficacy
Gaussian processes modeling for the prediction of polymeric nanoparticle formulation design to enhance encapsulation efficiency and therapeutic efficacy
Conventional drugs have been facing various drug delivery obstacles, including first-pass metabolism for oral medications,...
Cell-derived biomimetic nanoparticles for the targeted therapy of ALI/ARDS
Cell-derived biomimetic nanoparticles for the targeted therapy of ALI/ARDS
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common clinical critical diseases with high mor...
Targeted co-delivery of FOXM1 aptamer and DOX by nucleolin aptamer-functionalized pH-responsive biocompatible nanodelivery system to enhance therapeutic efficacy against breast cancer: in vitro and in vivo
Targeted co-delivery of FOXM1 aptamer and DOX by nucleolin aptamer-functionalized pH-responsive biocompatible nanodelivery system to enhance therapeutic efficacy against breast cancer: in vitro and in vivo
Targeted nanodelivery systems offer a promising approach to cancer treatment, including the most common cancer in women, b...
Advancements in microneedle fabrication techniques: artificial intelligence assisted 3D-printing technology
Advancements in microneedle fabrication techniques: artificial intelligence assisted 3D-printing technology
Microneedles (MNs) are micron-scale needles that are a painless alternative to injections for delivering drugs through the...
Exosome: From biology to drug delivery
Exosome: From biology to drug delivery
In recent years, different advancements have been observed in nanosized drug delivery systems. Factors such as stability, ...
ApoE—functionalization of nanoparticles for targeted brain delivery—a feasible method for polyplexes?
ApoE—functionalization of nanoparticles for targeted brain delivery—a feasible method for polyplexes?
The blood–brain barrier (BBB) poses a major obstacle in the treatment of all types of central nervous system (CNS) d...
Research progress on nanotechnology of traditional Chinese medicine to enhance the therapeutic effect of osteoarthritis
Research progress on nanotechnology of traditional Chinese medicine to enhance the therapeutic effect of osteoarthritis
Osteoarthritis (OA) is a prevalent chronic condition that primarily impacts the articular cartilage and surrounding bone t...
Antibiotic resistance and tolerance: What can drug delivery do against this global threat?
Antibiotic resistance and tolerance: What can drug delivery do against this global threat?
Antimicrobial resistance and tolerance (AMR&T) are urgent global health concerns, with alarmingl...
Bibliometric and visualized analysis of cancer nanomedicine from 2013 to 2023
Bibliometric and visualized analysis of cancer nanomedicine from 2013 to 2023
Cancer nanomedicine has been an emerging field for drug development against malignant tumors during the past three decades...
Design, optimization, and evaluation for a long-time-released transdermal microneedle delivery system containing estradiol
Design, optimization, and evaluation for a long-time-released transdermal microneedle delivery system containing estradiol
Transdermal drug delivery systems (TDDS) have drawbacks such as poor absorption, low blood concentration, and delayed effe...
Multicellular tumor spheroid model to study the multifaceted role of tumor-associated macrophages in PDAC
Multicellular tumor spheroid model to study the multifaceted role of tumor-associated macrophages in PDAC
While considerable efforts have been made to develop new therapies, progress in the treatment of pancreatic cancer has so ...
Enhancing transmucosal delivery of CBD through nanoemulsion: in vitro and in vivo studies
Enhancing transmucosal delivery of CBD through nanoemulsion: in vitro and in vivo studies
Cannabidiol (CBD) has gained significant attention as a complementary and alternative medicine due to its promising therap...
Optimized gravity-driven intranasal drop administration delivers significant doses to the ostiomeatal complex and maxillary sinus
Optimized gravity-driven intranasal drop administration delivers significant doses to the ostiomeatal complex and maxillary sinus
Chronic and allergic rhinosinusitis impacts approximately 12% of the global population. Challenges in rhinosinusitis treat...
Retraction Note: Co-delivery of doxorubicin and SIS3 by folate-targeted polymeric micelles for overcoming tumor multidrug resistance
Retraction Note: Co-delivery of doxorubicin and SIS3 by folate-targeted polymeric micelles for overcoming tumor multidrug resistance
Cite this articleWang, S., Tan, X., Zhou, Q. et al. Retraction Note: Co-delivery of doxorubicin and SIS3 by folate-targete...
Clopidogrel-loaded vascular grafts prepared using digital light processing 3D printing
Clopidogrel-loaded vascular grafts prepared using digital light processing 3D printing
The leading cause of death worldwide and a significant factor in decreased quality of life are the cardiovascular diseases...
Dual delivery systems combining nanocrystals and dissolving microneedles for improved local vaginal delivery of fluconazole
Dual delivery systems combining nanocrystals and dissolving microneedles for improved local vaginal delivery of fluconazole
Fluconazole (FLZ) has been widely used in the treatment of infection caused by Candida albicans, including the treatment o...
Unravelling the role of microneedles in drug delivery: Principle, perspectives, and practices
Unravelling the role of microneedles in drug delivery: Principle, perspectives, and practices
In recent year, the research of transdermal drug delivery systems has got substantial attention towards the development of...
Aqueous remote loading of model cationic peptides in uncapped poly(lactide-co-glycolide) microspheres for long-term controlled release
Aqueous remote loading of model cationic peptides in uncapped poly(lactide-co-glycolide) microspheres for long-term controlled release
Remote loading microencapsulation of peptides into polymer microspheres without organic solvent represents a promising alt...
Freeze-drying revolution: unleashing the potential of lyophilization in advancing drug delivery systems
Freeze-drying revolution: unleashing the potential of lyophilization in advancing drug delivery systems
Lyophilization also known as freeze-drying is a technique that has been employed to enhance the long-term durability of na...
Raloxifene encapsulated spanlastic nanogel for the prevention of bone fracture risk via transdermal administration: Pharmacokinetic and efficacy study in animal model
Raloxifene encapsulated spanlastic nanogel for the prevention of bone fracture risk via transdermal administration: Pharmacokinetic and efficacy study in animal model
This research work is to evaluate spanlastic-loaded raloxifene (RLX) nanogel administration via the transdermal route to a...
3D printing injectable microbeads using a composite liposomal ink for local treatment of peritoneal diseases
3D printing injectable microbeads using a composite liposomal ink for local treatment of peritoneal diseases
The peritoneal cavity offers an attractive administration route for challenging-to-treat diseases, such as peritoneal carc...
Progress of nanomaterials in the treatment of thrombus
Progress of nanomaterials in the treatment of thrombus
Thrombus has long been the major contributor of death and disability because it can cause adverse effects to varying degre...
Characterization of critical parameters using an air–liquid interface model with RPMI 2650 cells for permeability studies of small molecules
Characterization of critical parameters using an air–liquid interface model with RPMI 2650 cells for permeability studies of small molecules
The field of nasal drug delivery gained enormously on interest over the past decade. Performing nasal in vivo studies is e...
Anticancer effect of hUC-MSC-derived exosome-mediated delivery of PMO-miR-146b-5p in colorectal cancer
Anticancer effect of hUC-MSC-derived exosome-mediated delivery of PMO-miR-146b-5p in colorectal cancer
Antisense oligonucleotide (ASO) is a novel therapeutic platform for targeted cancer therapy. Previously, we have demonstra...
The implications of lipid mobility, drug-enhancers (surfactants)-skin interaction, and TRPV1 activation on licorice flavonoid permeability
The implications of lipid mobility, drug-enhancers (surfactants)-skin interaction, and TRPV1 activation on licorice flavonoid permeability
Licorice flavonoids (LFs) are derived from perennial herb licorice and have been attaining a considerable interest in cosm...
Construction of PLGA nanoparticles modified with RWrNM and DLPC and their application in acute rhinosinusitis
Construction of PLGA nanoparticles modified with RWrNM and DLPC and their application in acute rhinosinusitis
In an effort to overcome the nasal mucus barrier and epithelial barrier, as well as reduce entry into the bloodstream, we ...
Unmet technological demands in orodispersible films for age-appropriate paediatric drug delivery
Unmet technological demands in orodispersible films for age-appropriate paediatric drug delivery
Age-appropriateness of a formulation is the ability to deliver variable but accurate doses to the paediatric population in...
Preparation, characterization, pharmacokinetics and ulcerative colitis treatment of hyperoside-loaded mixed micelles
Preparation, characterization, pharmacokinetics and ulcerative colitis treatment of hyperoside-loaded mixed micelles
At present, ulcerative colitis (UC) has become a global disease due to its high incidence. Hyperoside (HYP) is a naturally...
Tunable polymeric micelles for taxane and corticosteroid co-delivery
Tunable polymeric micelles for taxane and corticosteroid co-delivery
Nanomedicine holds promise for potentiating drug combination therapies. Increasing (pre)clinical evidence is available exe...
A comparative study on the preparation and evaluation of solubilizing systems for silymarin
A comparative study on the preparation and evaluation of solubilizing systems for silymarin
Silymarin (SM) exhibits clinical efficacy in treating liver injuries, cirrhosis, and chronic hepatitis. However, its limit...
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