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Influence of recipient KRAS gene rs712 polymorphisms on the overall survival rate of hepatocellular carcinoma after hepatic transplantation
Influence of recipient KRAS gene rs712 polymorphisms on the overall survival rate of hepatocellular carcinoma after hepatic transplantation
Hepatocellular carcinoma (HCC) recurrence appears commonly after liver transplantation (LT), and it severely affected the ...
Risk of subsequent primary cancers in bladder cancer survivors
Risk of subsequent primary cancers in bladder cancer survivors
We aimed to investigate the risk of bladder cancer (BCa) survivors developing or dying from 15 specific-subsequent primary...
Genetics, diet, microbiota, and metabolome: partners in crime for colon carcinogenesis
Genetics, diet, microbiota, and metabolome: partners in crime for colon carcinogenesis
Colorectal cancer (CRC) ranks among the most prevalent malignant tumors worldwide, with a multifactorial etiology encompas...
Identifying the prognostic significance of mitophagy-associated genes in multiple myeloma: a novel risk model construction
Identifying the prognostic significance of mitophagy-associated genes in multiple myeloma: a novel risk model construction
Multiple myeloma (MM) is a highly heterogeneous hematological malignancy that is currently incurable. Individualized thera...
GUCA2A dysregulation as a promising biomarker for accurate diagnosis and prognosis of colorectal cancer
GUCA2A dysregulation as a promising biomarker for accurate diagnosis and prognosis of colorectal cancer
Colorectal cancer is a leading cause of global mortality and presents a significant barrier to improving life expectancy. ...
Early minimal residual disease eradication in light chain amyloidosis generates deeper and faster cardiac response
Early minimal residual disease eradication in light chain amyloidosis generates deeper and faster cardiac response
Minimal residual disease (MRD) is of growing interest in light chain (AL) amyloidosis and is associated with higher rates ...
Development and validation of a model for predicting who can benefit from multiple TACE in HCC patients
Development and validation of a model for predicting who can benefit from multiple TACE in HCC patients
This study was to develop and validate a model for predicting who can benefit from multiple transcatheter arterial chemoem...
Tumor-immune hybrid cells evade the immune response and potentiate colorectal cancer metastasis through CTLA4
Tumor-immune hybrid cells evade the immune response and potentiate colorectal cancer metastasis through CTLA4
Understanding the metastatic cascade is critical for the treatment and prevention of cancer-related death. Within a tumor,...
Analysis of METTL14 expression in pancreatic cancer and adjacent tissues and its prognostic value for patient outcomes
Analysis of METTL14 expression in pancreatic cancer and adjacent tissues and its prognostic value for patient outcomes
This study aims to analyze the differential expression of METTL14 in pancreatic cancer (PC) tissues and adjacent normal ti...
Clinical characteristics and prognosis analysis of pseudomonas aeruginosa bloodstream infection in adults: a retrospective study
Clinical characteristics and prognosis analysis of pseudomonas aeruginosa bloodstream infection in adults: a retrospective study
Pseudomonas aeruginosa bloodstream infections (PA BSIs) in adults, especially those complicated by sepsis, are associated ...
A systematic review and meta-analysis of the endothelial-immune candidate biomarker endoglin in rheumatic diseases
A systematic review and meta-analysis of the endothelial-immune candidate biomarker endoglin in rheumatic diseases
Existing challenges in accurately diagnosing various rheumatic diseases (RDs) have stimulated the search for novel biomark...
Chronobiological disruptions: unravelling the interplay of shift work, circadian rhythms, and vascular health in the context of stroke risk
Chronobiological disruptions: unravelling the interplay of shift work, circadian rhythms, and vascular health in the context of stroke risk
Shift work, particularly night shifts, disrupts circadian rhythms and increases stroke risk. This manuscript explores the ...
Current biological implications and clinical relevance of metastatic circulating tumor cells
Current biological implications and clinical relevance of metastatic circulating tumor cells
Metastatic disease and cancer recurrence are the primary causes of cancer-related deaths. Circulating tumor cells (CTCs) a...
The prognostic implications and oncogenic role of NSUN5 in clear cell renal cell carcinoma
The prognostic implications and oncogenic role of NSUN5 in clear cell renal cell carcinoma
Clear cell renal cell carcinoma (ccRCC), a predominant form of urinary malignancy, requires the identification of reliable...
Development of hepatocellular carcinoma organoid model recapitulating HIF-1A metabolic signature
Development of hepatocellular carcinoma organoid model recapitulating HIF-1A metabolic signature
Hypoxia is one of the main hallmarks of hepatocellular carcinoma (HCC) resulting from improper oxygenation and insufficien...
Hodgkin lymphoma: the role of EBV plasma viral load testing in an HIV-endemic setting
Hodgkin lymphoma: the role of EBV plasma viral load testing in an HIV-endemic setting
South Africa has a high burden of human immune deficiency virus (HIV)-associated Hodgkin lymphoma (HL) which is typically ...
The bacterial microbiome and cancer: development, diagnosis, treatment, and future directions
The bacterial microbiome and cancer: development, diagnosis, treatment, and future directions
The term "microbiome" refers to the collection of bacterial species that reside in the human body's tissues....
Bispecific antibodies in clinical practice: Understanding recent advances and current place in cancer treatment landscape
Bispecific antibodies in clinical practice: Understanding recent advances and current place in cancer treatment landscape
Immunotherapy has changed the treatment landscape of cancer in the past decade. Amongst various forms of immunotherapy, ma...
Autophagy-based therapy for hepatocellular carcinoma: from standard treatments to combination therapy, oncolytic virotherapy, and targeted nanomedicines
Autophagy-based therapy for hepatocellular carcinoma: from standard treatments to combination therapy, oncolytic virotherapy, and targeted nanomedicines
Human hepatocellular carcinoma (HCC) has been identified as a significant cause of mortality worldwide. In recent years, e...
External validation of a four-tiered grading system for chromophobe renal cell carcinoma
External validation of a four-tiered grading system for chromophobe renal cell carcinoma
This study aimed to validate the prognostic value of a four-tiered grading system recently proposed by Avulova et al. and ...
The casual relationship between autoimmune diseases and multiple myeloma: a Mendelian randomization study
The casual relationship between autoimmune diseases and multiple myeloma: a Mendelian randomization study
Observational studies showed possible associations between systemic lupus erythematosus and multiple myeloma. However, whe...
Clinical features and prognosis of ANCA-associated vasculitis patients who were double-seropositive for myeloperoxidase-ANCA and proteinase 3-ANCA
Clinical features and prognosis of ANCA-associated vasculitis patients who were double-seropositive for myeloperoxidase-ANCA and proteinase 3-ANCA
Anti-neutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) patients with dual positivity for proteinase...
Investigation of long non-coding RNAs in extracellular vesicles from low-volume blood serum specimens of colorectal cancer patients
Investigation of long non-coding RNAs in extracellular vesicles from low-volume blood serum specimens of colorectal cancer patients
Colorectal cancer (CRC) is the second most prevalent cancer type worldwide, which highlights the urgent need for non-invas...
Low platelet count at diagnosis of anti-neutrophil cytoplasmic antibody-associated vasculitis is correlated with the severity of disease and renal prognosis
Low platelet count at diagnosis of anti-neutrophil cytoplasmic antibody-associated vasculitis is correlated with the severity of disease and renal prognosis
Antineutrophil cytoplasmic antibody-associated vasculitis (AAV) is an autoimmune disease that involves inflammation of blo...
Non-invasive prenatal test identifies circulating cell-free DNA chromosomal abnormalities derived from clonal hematopoiesis in aggressive hematological malignancies
Non-invasive prenatal test identifies circulating cell-free DNA chromosomal abnormalities derived from clonal hematopoiesis in aggressive hematological malignancies
Liquid biopsy is a minimally invasive diagnostic tool for identification of tumor-related mutations in circulating cell-fr...
Supporting the decision to perform molecular profiling for cancer patients based on routinely collected data through the use of machine learning
Supporting the decision to perform molecular profiling for cancer patients based on routinely collected data through the use of machine learning
Personalized medicine offers targeted therapy options for cancer treatment. However, the decision whether to include a pat...
A MiR181/Sirtuin1 regulatory circuit modulates drug response in biliary cancers
A MiR181/Sirtuin1 regulatory circuit modulates drug response in biliary cancers
Despite recent advances, biliary tract cancer (BTC) remains one of the most lethal tumor worldwide due to late diagnosis, ...
Antinuclear antibodies may predict the development of immune-related adverse events in asymptomatic patients treated with immune checkpoint inhibitors: results from a single-center cohort
Antinuclear antibodies may predict the development of immune-related adverse events in asymptomatic patients treated with immune checkpoint inhibitors: results from a single-center cohort
We aim at investigating the association between subclinical autoimmunity and immune-related adverse events (irAEs) in a co...
Genetic alterations and allele frequency of BRAF V600E and TERT mutation in papillary thyroid carcinoma with intermediate-to-high recurrence risk: a retrospective study
Genetic alterations and allele frequency of BRAF V600E and TERT mutation in papillary thyroid carcinoma with intermediate-to-high recurrence risk: a retrospective study
The predictive value of allele frequency (AF) of BRAF V600E and TERT mutations in papillary thyroid carcinoma (PTC) remain...
Clinical impact of transient lymphopenia
Clinical impact of transient lymphopenia
Transient or persistent immunosuppression is a known risk factor for morbidity and mortality in critically ill patients. A...
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