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NF-κB-mediated enhancement of H3K27me3 through EZH2: a mechanism to suppress pyocyanin-induced autophagy in macrophages
NF-κB-mediated enhancement of H3K27me3 through EZH2: a mechanism to suppress pyocyanin-induced autophagy in macrophages
Histone modification is a key mechanism of epigenetic regulation. Our previous study demonstrated that histone H3 acetylat...
Risk analysis of the association between EASIX and all-cause mortality in critical ill patients with atrial fibrillation: a retrospective study from MIMIC-IV database
Risk analysis of the association between EASIX and all-cause mortality in critical ill patients with atrial fibrillation: a retrospective study from MIMIC-IV database
The Endothelial Activation and Stress Index (EASIX) is a recognized marker of vascular endothelial health but has limited ...
Opsin3 regulates cell proliferation, migration, and apoptosis in lung adenocarcinoma via GPX3 pathway
Opsin3 regulates cell proliferation, migration, and apoptosis in lung adenocarcinoma via GPX3 pathway
Despite recent progress in understanding lung adenocarcinoma (LUAD) and the emergence of new therapeutic strategies, LUAD ...
Applicability of ultrasound-guided puncture and laparoscopic cystectomy for ovarian endometriosis cyst: a non-randomized trial
Applicability of ultrasound-guided puncture and laparoscopic cystectomy for ovarian endometriosis cyst: a non-randomized trial
Ovarian endometriosis cysts are common gynecological conditions and are mostly benign. While many cysts resolve spontaneou...
LPM electrode loaded with RAPA-PLGA drug sustained-release system can reduce local fibrous tissue hyperplasia and local bioelectrical impedance
LPM electrode loaded with RAPA-PLGA drug sustained-release system can reduce local fibrous tissue hyperplasia and local bioelectrical impedance
This study aims to design and fabricate a leadless pacemaker (LPM) electrode loaded with rapamycin (RAPA)–poly(lacti...
Characteristics and outcomes of patients hospitalized for infection with Influenza A, SARS-CoV-2 or respiratory syncytial virus in the season 2023/2024 in a large German primary care centre
Characteristics and outcomes of patients hospitalized for infection with Influenza A, SARS-CoV-2 or respiratory syncytial virus in the season 2023/2024 in a large German primary care centre
In addition to the persistence of SARS-CoV-2 infections, those with Influenza A/B and RSV have reappeared in 2022/23. To c...
Association between loneliness and incident atrial fibrillation across different genetic predisposition: findings from the UK Biobank
Association between loneliness and incident atrial fibrillation across different genetic predisposition: findings from the UK Biobank
Loneliness has garnered significant attention globally, with extensive exploration of its association with cardiovascular ...
Causal effect of gut microbiota on occurrence of herpes zoster and postherpetic neuralgia, and role of Tyzzerella 3
Causal effect of gut microbiota on occurrence of herpes zoster and postherpetic neuralgia, and role of Tyzzerella 3
Previous research has established connections between gut microbiota, immune modulation, and several virus-related disease...
Enhanced recovery after surgery (ERAS) improves outcomes in elderly patients undergoing short-level lumbar fusion surgery: a retrospective study of 333 cases
Enhanced recovery after surgery (ERAS) improves outcomes in elderly patients undergoing short-level lumbar fusion surgery: a retrospective study of 333 cases
Degenerative lumbar disease significantly impairs the quality of life in elderly individuals, with short-segment lumbar de...
Surgical treatment of long-term epilepsy-associated tumors guided by stereoelectroencephalography
Surgical treatment of long-term epilepsy-associated tumors guided by stereoelectroencephalography
Accurate detection and resection of the epileptogenic zone (EZ) in patients with long-term epilepsy-associated tumors (LEA...
Association of α-HBDH levels with the severity and recurrence after acute ischemic stroke
Association of α-HBDH levels with the severity and recurrence after acute ischemic stroke
α-HBDH serves as a biomarker of myocardial damage and is implicated in adverse outcomes across various critical illne...
Slit2–Robo4 signal pathway and tight junction in intestine mediate LPS-induced inflammation in mice
Slit2–Robo4 signal pathway and tight junction in intestine mediate LPS-induced inflammation in mice
Sepsis is one of the most common clinical diseases, which is characterized by a serious and uncontrollable inflammatory re...
Causal relationship between primary sclerosing cholangitis and systemic lupus erythematosus: a bidirectional Mendelian randomization study
Causal relationship between primary sclerosing cholangitis and systemic lupus erythematosus: a bidirectional Mendelian randomization study
Observational studies have found a link between two autoimmune diseases, namely, primary sclerosing cholangitis (PSC) and ...
Therapeutic potential of extracellular vesicles from diverse sources in cancer treatment
Therapeutic potential of extracellular vesicles from diverse sources in cancer treatment
Cancer, a prevalent and complex disease, presents a significant challenge to the medical community. It is characterized by...
Study on the effect and mechanism of Zhenzhu Tongluo pills in treating diabetic peripheral neuropathy injury
Study on the effect and mechanism of Zhenzhu Tongluo pills in treating diabetic peripheral neuropathy injury
As a traditional Mongolian medicine, Zhenzhu Tongluo pills has played a good neuroprotective function in clinic. However, ...
Changes of Mycobacterium tuberculosis specific antigen-stimulated CD27−CD38+IFN-γ+CD4+ T cells before and after anti-tuberculosis treatment
Changes of Mycobacterium tuberculosis specific antigen-stimulated CD27−CD38+IFN-γ+CD4+ T cells before and after anti-tuberculosis treatment
The aim of the study was to investigate whether the expression of CD27−CD38+ in interferon (IFN)-γ+CD4+ T cells...
Serum proteome analysis identifies a potential biomarker for axial psoriatic arthritis
Serum proteome analysis identifies a potential biomarker for axial psoriatic arthritis
To identify potential serum biomarkers for differentiating between axial psoriatic arthritis (axPsA) and peripheral psoria...
Advances in secondary prevention mechanisms of macrovascular complications in type 2 diabetes mellitus patients: a comprehensive review
Advances in secondary prevention mechanisms of macrovascular complications in type 2 diabetes mellitus patients: a comprehensive review
Type 2 diabetes mellitus (T2DM) poses a significant global health burden. This is particularly due to its macrovascular co...
Dysregulated cholesterol regulatory genes in hepatocellular carcinoma
Dysregulated cholesterol regulatory genes in hepatocellular carcinoma
Cholesterol is an indispensable component in mammalian cells, and cholesterol metabolism performs important roles in vario...
Causal associations between genetically determined common psychiatric disorders and the risk of falls: evidence from Mendelian randomization
Causal associations between genetically determined common psychiatric disorders and the risk of falls: evidence from Mendelian randomization
The causal associations between psychiatric disorders and falls risk remains uncertain. Consequently, this study aimed to ...
Mesenchymal stem cells-derived exosomes: novel carriers for nanoparticle to combat cancer
Mesenchymal stem cells-derived exosomes: novel carriers for nanoparticle to combat cancer
The advancement in novel cancer therapeutics brought a platform combining the properties of exosomes with nanoparticles to...
Differentiation between cerebral alveolar echinococcosis and brain metastases with radiomics combined machine learning approach
Differentiation between cerebral alveolar echinococcosis and brain metastases with radiomics combined machine learning approach
Cerebral alveolar echinococcosis (CAE) and brain metastases (BM) share similar in locations and imaging appearance. Howeve...
Systemic immune-inflammation index (SII) and the risk of all-cause, cardiovascular, and cardio-cerebrovascular mortality in the general population
Systemic immune-inflammation index (SII) and the risk of all-cause, cardiovascular, and cardio-cerebrovascular mortality in the general population
An elevated systemic immune-inflammation index (SII) is associated with higher mortality in patients with coronary artery ...
Comparison of different internal fixation models in ankle arthrodesis using 3D finite-element analysis
Comparison of different internal fixation models in ankle arthrodesis using 3D finite-element analysis
The purpose of this study is to use three-dimensional finite-element analysis to better understand the biomechanical featu...
Association between statin use on delirium and 30-day mortality in patients with chronic obstructive pulmonary disease in the intensive care unit
Association between statin use on delirium and 30-day mortality in patients with chronic obstructive pulmonary disease in the intensive care unit
Delirium occurs frequently in patients with chronic obstructive pulmonary disease in the intensive care unit. Effective pr...
Initiation and rapid titration of methadone and slow-release oral morphine (SROM) in an acute care, inpatient setting: a case series
Initiation and rapid titration of methadone and slow-release oral morphine (SROM) in an acute care, inpatient setting: a case series
Methadone titration in an outpatient setting typically involves initiation with subtherapeutic doses with slow titration t...
Treatment of brainstem and fourth ventricle lesions by the full neuroendoscopic telovelar approach
Treatment of brainstem and fourth ventricle lesions by the full neuroendoscopic telovelar approach
To explore the surgical techniques, advantages, and disadvantages of neuroendoscopic telovelar approach in the treatment o...
Disulfidptosis-related signatures for prognostic and immunotherapy reactivity evaluation in hepatocellular carcinoma
Disulfidptosis-related signatures for prognostic and immunotherapy reactivity evaluation in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the most common cancers in the world and a nonnegligible health concern ...
The value of the cinematic volume rendering technique: magnetic resonance imaging in diagnosing tumors associated with the brachial plexus
The value of the cinematic volume rendering technique: magnetic resonance imaging in diagnosing tumors associated with the brachial plexus
To examine the diagnostic advantages and clinical application value of the cinematic volume rendering technique (cVRT) whe...
SNAP25 is a potential target for early stage Alzheimer’s disease and Parkinson’s disease
SNAP25 is a potential target for early stage Alzheimer’s disease and Parkinson’s disease
Alzheimer’s disease (AD) and Parkinson’s disease (PD), two common irreversible neurodegenerative diseases, sha...
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