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Assessment of biomarker stability and assay performance parameters for medical diagnosis: a case study of diagnosis of major depressive disorder
Assessment of biomarker stability and assay performance parameters for medical diagnosis: a case study of diagnosis of major depressive disorder
Aim: Assessing the stability profiles and assay performance of 24 biomarker assays in 32 biomarker/body fluid combinations...
Comparison of the effect of uric acid/albumin ratio on coronary slow flow with other inflammation-based markers
Comparison of the effect of uric acid/albumin ratio on coronary slow flow with other inflammation-based markers
Background: Many inflammation-based markers (IBMs) have been shown to be closely related to coronary slow flow (CSF), but ...
Platelet-to-lymphocyte ratio and lymphocyte-to-monocyte ratio in glaucoma: a meta-analysis
Platelet-to-lymphocyte ratio and lymphocyte-to-monocyte ratio in glaucoma: a meta-analysis
Aim: To explore the association between two systemic inflammation markers, platelet-to-lymphocyte ratio (PLR) and lymphocy...
Potential clinical significance of ALDH3B1 in auxiliary diagnosis of gastric cancer
Potential clinical significance of ALDH3B1 in auxiliary diagnosis of gastric cancer
Objective: This research aimed to explore a diagnostic method based on serum ALDH3B1 and to evaluate the clinical diagnost...
Association between serum homocysteine and postoperative acute kidney injury in patients undergoing cardiac surgery
Association between serum homocysteine and postoperative acute kidney injury in patients undergoing cardiac surgery
Background: To explore the relationship between homocysteine (Hcy) and cardiac surgery-associated acute kidney injury (AKI...
B-type natriuretic peptide levels at admission predict the prognosis of patients with infective endocarditis undergoing cardiac surgery
B-type natriuretic peptide levels at admission predict the prognosis of patients with infective endocarditis undergoing cardiac surgery
Purpose: The objective of this study was to explore the relationship between elevated B-type natriuretic peptide (BNP) lev...
Predictive role of neutrophil-to-platelet ratio in futile recanalization of patients after endovascular therapy
Predictive role of neutrophil-to-platelet ratio in futile recanalization of patients after endovascular therapy
Aim: To explore the association between the neutrophil-to-platelet ratio (NPR) and futile recanalization (FR) in patients ...
Relation between LRG1 and CD4+ T cells, cognitive impairment and neurological function in patients with acute ischemic stroke
Relation between LRG1 and CD4+ T cells, cognitive impairment and neurological function in patients with acute ischemic stroke
Objective: To assess the relationship between LRG1 and CD4+ T cells, cognitive impairment and neurological function in acu...
Meta-analysis of initial natriuretic peptides in the setting of sepsis-induced myocardial dysfunction
Meta-analysis of initial natriuretic peptides in the setting of sepsis-induced myocardial dysfunction
Aim: To investigate the association of initial brain natriuretic peptide (BNP) and N-terminal pro-BNP (NT-proBNP) with the...
Emerging roles of HOTAIR lncRNA in the pathogenesis and prognosis of cardiovascular diseases
Emerging roles of HOTAIR lncRNA in the pathogenesis and prognosis of cardiovascular diseases
Highlights HOTAIR, a long noncoding RNA, plays a role in the regulation of proteins involved in the pathogenesis of cardio...
Biomarkers: paving the way for diagnosis, prognosis and disease monitoring. Welcome to Volume 18
Biomarkers: paving the way for diagnosis, prognosis and disease monitoring. Welcome to Volume 18
Received 22 December 2023 Accepted 2 January 2024 ...
Associations between neutrophil-to-lymphocyte/platelet-to-lymphocyte and recovery in sudden sensorineural hearing loss
Associations between neutrophil-to-lymphocyte/platelet-to-lymphocyte and recovery in sudden sensorineural hearing loss
Aims: This study investigated the nonlinear associations between neutrophil-to-lymphocyte (NLR)/platelet-to-lymphocyte (PL...
Prognostic potency of plasma LRG1 measurement at multiple time points in acute ischemic stroke patients
Prognostic potency of plasma LRG1 measurement at multiple time points in acute ischemic stroke patients
Objective: This study aimed to investigate the prognostic potency of LRG1 in acute ischemic stroke (AIS) patients. Methods...
PLK4 reflects extrathyroidal invasion, high tumor stage and poor prognosis in papillary thyroid carcinoma patients
PLK4 reflects extrathyroidal invasion, high tumor stage and poor prognosis in papillary thyroid carcinoma patients
Objective: This study aimed to assess the value of PLK4 as a biomarker in papillary thyroid carcinoma (PTC). Methods: This...
MECOM: a bioinformatics and experimentally identified marker for the diagnosis and prognosis of lung adenocarcinoma
MECOM: a bioinformatics and experimentally identified marker for the diagnosis and prognosis of lung adenocarcinoma
Objective: We aimed to explore the clinical value of MDS1 and EVI1 complex locus (MECOM) in lung adenocarcinoma (LUAD). Me...
Study on red blood cell distribution width in children with severe Mycoplasma pneumoniae pneumonia
Study on red blood cell distribution width in children with severe Mycoplasma pneumoniae pneumonia
Background: This study aimed to investigate the clinical value of the red blood cell distribution width (RDW) in severe My...
C-reactive protein to albumin ratio may predict in-hospital mortality in non-ST elevation myocardial infarction
C-reactive protein to albumin ratio may predict in-hospital mortality in non-ST elevation myocardial infarction
Objective: The authors investigated the value of novel inflammatory markers, systemic immune-inflammation index and C-reac...
Linkage of CDC42 and T-helper cell ratio with anxiety, depression and quality of life in ST-elevation myocardial infarction
Linkage of CDC42 and T-helper cell ratio with anxiety, depression and quality of life in ST-elevation myocardial infarction
Objective: To investigate the correlations between CDC42 and T-cell subsets concerning anxiety, depression and quality of ...
Diagnostic predictability of serum miR-4793-3p and miR-1180-3p expression in community-acquired pneumonia
Diagnostic predictability of serum miR-4793-3p and miR-1180-3p expression in community-acquired pneumonia
Background: Early identification of community-acquired pneumonia (CAP) is crucial to prevent severe progression. Methods: ...
Prognostic and diagnostic roles of prolyl 4-hydroxylase subunit α members in breast cancer
Aim: We aimed to evaluate the diagnostic and prognostic values of P4HAs in breast cancer (BC) patients. Materials & me...
Osteopontin and galectin-3 as biomarkers of maladaptive right ventricular remodeling in pulmonary hypertension
Aim: This study assessed the utility of osteopontin (OPN) and galectin-3 (Gal-3) as biomarkers of maladaptive right ventri...
The potential of miR-499 plasmatic level as a biomarker of obstructive sleep apnea syndrome
Background: Obstructive sleep apnea syndrome (OSAS) is one of the most common sleep-related breathing disorders. The aim o...
Pre-analytical sample handling effects on blood cytokine levels: quality control of a COVID-19 biobank
Aim: We investigated the effect of pre-analytical sample handling variations on coronavirus disease 2019-relevant circulat...
Novel kidney injury biomarkers in a large cohort of children with sickle cell anemia
Aim: The aim of this study was to compare novel kidney injury biomarkers in sickle cell anemia (SCA) children with and wit...
Increased levels of circulating circular RNA (hsa_circ_0013587) may serve as a novel biomarker for pancreatic cancer
Aim: Circular RNA can serve as a biomarker for early diagnosis of pancreatic cancer. Materials & methods: Analyzed the...
Lymphocyte-to-monocyte ratio predicts survival after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
Aim: Lymphocyte-to-monocyte ratio (LMR) predicts overall survival (OS) in patients with colorectal cancer. We explored LMR...
Predictive value of circulating sex hormone-binding globulin for gestational diabetes: a meta-analysis
Aim: To detect predictive value of preconception or early pregnancy sex hormone-binding globulin (SHBG) for subsequent ges...
Associations between serum lipids and mannose levels in coronary artery disease among nondiabetic patients
Aim: Nondiabetic patients have been studied to determine whether modest elevations in plasma mannose levels may be associa...
Breast invasive ductal carcinoma diagnosis with a three-miRNA panel in serum
Aim: Breast cancer, especially invasive ductal carcinoma (IDC), is the cause of a great clinical burden. miRNA could be co...
National Early Warning Score 2 and laboratory predictors correlate with clinical deterioration in hospitalized patients with COVID-19
Aim: We aimed to determine the prognostic values of the National Early Warning Score 2 (NEWS2) and laboratory parameters d...
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