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Lipoamide Attenuates Hypertensive Myocardial Hypertrophy Through PI3K/Akt-Mediated Nrf2 Signaling Pathway
Lipoamide Attenuates Hypertensive Myocardial Hypertrophy Through PI3K/Akt-Mediated Nrf2 Signaling Pathway
The process of myocardial hypertrophy in hypertension can lead to excessive activation of oxidative stress. Lipoamide (ALM...
CD137 Signaling Mediates Pulmonary Artery Endothelial Cell Proliferation Under Hypoxia By Regulating Mitochondrial Dynamics
CD137 Signaling Mediates Pulmonary Artery Endothelial Cell Proliferation Under Hypoxia By Regulating Mitochondrial Dynamics
Altered mitochondrial dynamics affect pulmonary artery endothelial cells (PAECs) proliferation, contributing to the develo...
Changes in Cardiac Electrical Biomarker in Response to Coronary Arterial Occlusion: An Experimental Observation
Changes in Cardiac Electrical Biomarker in Response to Coronary Arterial Occlusion: An Experimental Observation
Cardiac electrical biomarker (CEB), an indicator of ischaemia-induced change in myocyte polarity, has been proposed for di...
Exploration of the Potential Biomarker FNDC5 for Discriminating Heart Failure in Patients with Coronary Atherosclerosis
Exploration of the Potential Biomarker FNDC5 for Discriminating Heart Failure in Patients with Coronary Atherosclerosis
Coronary atherosclerosis leading to ischemic artery disease is one of the etiological factors to develop heart failure (HF...
Transplantation of Human Embryonic Stem Cell–Derived Pericyte-Like Cells Transduced with Basic Fibroblast Growth Factor Promotes Angiogenic Recovery in Mice with Severe Chronic Hindlimb Ischemia
Transplantation of Human Embryonic Stem Cell–Derived Pericyte-Like Cells Transduced with Basic Fibroblast Growth Factor Promotes Angiogenic Recovery in Mice with Severe Chronic Hindlimb Ischemia
Critical limb ischemia (CLI) is a state of severe peripheral artery disease, with no effective treatment. Cell therapy has...
Percutaneous Alginate Hydrogel Endomyocardial Injection with a Novel Dedicated Catheter Delivery System: An Animal Feasibility Study
Percutaneous Alginate Hydrogel Endomyocardial Injection with a Novel Dedicated Catheter Delivery System: An Animal Feasibility Study
The objective of this preclinical study was to evaluate the feasibility and safety of transcatheter endocardial alginate h...
Circulating Proteome Analysis Identifies Reduced Inflammation After Initiation of Hemodynamic Support with Either Veno-Arterial Extracorporeal Membrane Oxygenation or Impella in Patients with Cardiogenic Shock
Circulating Proteome Analysis Identifies Reduced Inflammation After Initiation of Hemodynamic Support with Either Veno-Arterial Extracorporeal Membrane Oxygenation or Impella in Patients with Cardiogenic Shock
In-hospital mortality associated with cardiogenic shock (CS) remains high despite the use of percutaneous assist devices. ...
Allograft Model of Aortic Arch Segment Grafting to Abdominal Aorta Through End-to-Side Anastomosis in Mice
Allograft Model of Aortic Arch Segment Grafting to Abdominal Aorta Through End-to-Side Anastomosis in Mice
The mouse aortic transplantation model is a valuable tool for investigating the mechanisms of atherosclerosis regression, ...
Impact of Perivascular Adipose Tissue on Neointimal Formation Following Endovascular Placement
Impact of Perivascular Adipose Tissue on Neointimal Formation Following Endovascular Placement
Following the placement of endovascular implants, perivascular adipose tissue (PVAT) becomes an early sensor of vascular i...
ALK1 Deficiency Impairs the Wound-Healing Process and Increases Mortality in Murine Model of Myocardial Infarction
ALK1 Deficiency Impairs the Wound-Healing Process and Increases Mortality in Murine Model of Myocardial Infarction
The functional role of TGFβ type I receptor, activin-like kinase (ALK)-1 in post-myocardial infarction (MI) cardiac r...
Correction: New Insights into the Genetics of Cardiomyopathies
Correction: New Insights into the Genetics of Cardiomyopathies
Share this articleAnyone you share the following link with will be able to read this content:Get shareable linkSorry, a sh...
T-cell Immunoglobulin and Mucin Domain 3 in Circulating Monocytes as a Novel Biomarker for Coronary Artery Disease
T-cell Immunoglobulin and Mucin Domain 3 in Circulating Monocytes as a Novel Biomarker for Coronary Artery Disease
The diagnostic role of T-cell immunoglobulin and mucin domain 3 (Tim-3) expression levels in circulating monocytes in coro...
RNA Sequencing of Whole Blood in Premature Coronary Artery Disease: Identification of Novel Biomarkers and Involvement of T Cell Imbalance
RNA Sequencing of Whole Blood in Premature Coronary Artery Disease: Identification of Novel Biomarkers and Involvement of T Cell Imbalance
Serum biomarkers were explored based on the peripheral blood gene expression profiles of premature coronary artery disease...
New Insights into the Genetics of Cardiomyopathies
New Insights into the Genetics of Cardiomyopathies
Research into the genetic aetiology of cardiomyopathies, and the clinical applica...
The Trouble with Trabeculation: How Genetics Can Help to Unravel a Complex and Controversial Phenotype
The Trouble with Trabeculation: How Genetics Can Help to Unravel a Complex and Controversial Phenotype
Excessive trabeculation of the cardiac left ventricular wall is a complex phenotypic substrate associated with various phy...
A Systematic Approach Focused on Machine Learning Models for Exploring the Landscape of Physiological Measurement and Estimation Using Photoplethysmography (PPG)
A Systematic Approach Focused on Machine Learning Models for Exploring the Landscape of Physiological Measurement and Estimation Using Photoplethysmography (PPG)
A non-invasive optical technique known as photoplethysmography (PPG) can be used to provide various physiological measurem...
Genetically Proxied Therapeutic Effect of Metformin Use, Blood Pressure, and Hypertension’s Risk: a Drug Target-Based Mendelian Randomization Study
Genetically Proxied Therapeutic Effect of Metformin Use, Blood Pressure, and Hypertension’s Risk: a Drug Target-Based Mendelian Randomization Study
In this work, we aim to evaluate the association of the genetically proxied effect of metformin on blood pressure (BP) and...
Role of Flow-Sensitive Endothelial Genes in Atherosclerosis and Antiatherogenic Therapeutics Development
Role of Flow-Sensitive Endothelial Genes in Atherosclerosis and Antiatherogenic Therapeutics Development
Atherosclerosis is a chronic inflammatory disease that is the underlying cause of cardiovascular disease which initiates f...
The Fragmented QRS Complex in Lead V1: Time for an Update of the Athlete’s ECG?
The Fragmented QRS Complex in Lead V1: Time for an Update of the Athlete’s ECG?
Differentiating between ECG patterns related to athletes' heart remodeling and pathological findings is a challenge in...
Slow-Reflow and Prognosis in Patients with High Parathyroid Hormone Levels Undergoing Primary Percutaneous Coronary Intervention for Acute ST-Segment Elevation Myocardial Infarction
Slow-Reflow and Prognosis in Patients with High Parathyroid Hormone Levels Undergoing Primary Percutaneous Coronary Intervention for Acute ST-Segment Elevation Myocardial Infarction
We aimed to evaluate the correlation among serum parathyroid hormone (PTH) and slow-reflow during primary percutaneous cor...
ASSESS-IE: a Novel Risk Score for Patients with Infective Endocarditis
ASSESS-IE: a Novel Risk Score for Patients with Infective Endocarditis
Mortality in patients with infective endocarditis (IE) remains high. The existing risk scores are relatively complex with ...
Upregulation of eIF2α by m6A modification accelerates the proliferation of pulmonary artery smooth muscle cells in MCT-induced pulmonary arterial hypertension rats
Upregulation of eIF2α by m6A modification accelerates the proliferation of pulmonary artery smooth muscle cells in MCT-induced pulmonary arterial hypertension rats
Pulmonary arterial hypertension (PAH) is a malignant cardiovascular disease. Eukaryotic initiation factor 2α (eIF2 ...
Compound Heterozygosity for Late-Onset Cardiomyopathy-Causative ALPK3 Coding Variant and Novel Intronic Variant Cause Infantile Hypertrophic Cardiomyopathy
Compound Heterozygosity for Late-Onset Cardiomyopathy-Causative ALPK3 Coding Variant and Novel Intronic Variant Cause Infantile Hypertrophic Cardiomyopathy
Hypertrophic and dilated cardiomyopathy (HCM, DCM) are leading causes of cardiovascular morbidity and mortality in childre...
Exercise Training Improves Brachial Artery Endothelial Function, but Does Not Alter Inflammatory Biomarkers in Patients with Peripheral Artery Disease: a Systematic Review and Meta-analysis
Exercise Training Improves Brachial Artery Endothelial Function, but Does Not Alter Inflammatory Biomarkers in Patients with Peripheral Artery Disease: a Systematic Review and Meta-analysis
The study aimed to systematically review the effects of exercise training (EX) on brachial artery flow-mediated dilation (...
CREB1 Silencing Protects Against Inflammatory Response in Rats with Deep Vein Thrombosis Through Reducing RPL9 Expression and Blocking NF-κB Signaling
CREB1 Silencing Protects Against Inflammatory Response in Rats with Deep Vein Thrombosis Through Reducing RPL9 Expression and Blocking NF-κB Signaling
Apoptosis and inflammation of vascular endothelial cells (VECs) are the most important causes of deep vein thrombosis (DVT...
Enhanced Levels of Adiposity, Stretch and Fibrosis Markers in Patients with Coexistent Heart Failure and Atrial Fibrillation
Enhanced Levels of Adiposity, Stretch and Fibrosis Markers in Patients with Coexistent Heart Failure and Atrial Fibrillation
The coexistence of heart failure (HF) and atrial fibrillation (AF) worsens the prognosis of patients. We aimed to study th...
Immune-Mediated Denervation of the Pineal Gland: a Potential Mechanism for Sleep Disturbance in Cardiac Disease
Immune-Mediated Denervation of the Pineal Gland: a Potential Mechanism for Sleep Disturbance in Cardiac Disease
Editor-in-Chief Enrique Lara-Pezzi oversaw the review of this article.Publisher's NoteSpringer Nature remains neutral with...
Computational Modelling Enabling In Silico Trials for Cardiac Physiologic Pacing
Computational Modelling Enabling In Silico Trials for Cardiac Physiologic Pacing
Conduction system pacing (CSP) has the potential to achieve physiological-paced activation by pacing the ventricular condu...
Mesenchymal Stem Cell-Derived Exosomes and Their MicroRNAs in Heart Repair and Regeneration
Mesenchymal Stem Cell-Derived Exosomes and Their MicroRNAs in Heart Repair and Regeneration
Mesenchymal stem cells (MSCs) can be differentiated into cardiac, endothelial, and smooth muscle cells. Therefore, MSC-bas...
Generation of Autologous Vascular Endothelial Cells for Patients with Peripheral Artery Disease
Generation of Autologous Vascular Endothelial Cells for Patients with Peripheral Artery Disease
Peripheral artery disease (PAD) is a prevalent cardiovascular disease with risks of limb loss. Our objective is to establi...
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