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MicroRNA regulation of BAG3
MicroRNA regulation of BAG3
B-cell lymphoma 2 (Bcl-2)-associated athanogene 3 (BAG3) protein is a member of BAG family of co-chaperones that modulates...
Galangin: A metabolite that suppresses anti-neoplastic activities through modulation of oncogenic targets
Galangin: A metabolite that suppresses anti-neoplastic activities through modulation of oncogenic targets
With the dramatic increase in cancer incidence all over the world in the last decades, studies on identifying novel effici...
Survival stratification for colorectal cancer via multi-omics integration using an autoencoder-based model
Survival stratification for colorectal cancer via multi-omics integration using an autoencoder-based model
Prognosis stratification in colorectal cancer helps to address cancer heterogeneity and contributes to the improvement of ...
High-quality RNA improves sensitivity of SARS-CoV-2 detection by colorimetric RT-LAMP
High-quality RNA improves sensitivity of SARS-CoV-2 detection by colorimetric RT-LAMP
The global SARS-CoV-2 pandemic requires a rapid, reliable, and user-friendly diagnostic test to help control the spread of...
Mild hypobaric hypoxia influences splenic proliferation during the later phase of stress erythropoiesis
Mild hypobaric hypoxia influences splenic proliferation during the later phase of stress erythropoiesis
Tissue trauma and hemorrhagic shock are common battlefield injuries that can induce hypoxia, inflammation, and/or anemia. ...
Simultaneous visible light optical coherence tomography and near infrared OCT angiography in retinal pathologies: A case study
Simultaneous visible light optical coherence tomography and near infrared OCT angiography in retinal pathologies: A case study
A dual-channel optical coherence tomography system with wavelengths in the visible and near-infrared light ranges can prov...
Calcitriol ameliorates damage in high-salt diet-induced hypertension: Evidence of communication with the gut–kidney axis
Calcitriol ameliorates damage in high-salt diet-induced hypertension: Evidence of communication with the gut–kidney axis
Several studies have established a link between high-salt diet, inflammation, and hypertension. Vitamin D supplementation ...
Metabolic analysis of infants with bronchopulmonary dysplasia under early nutrition therapy: An observational cohort study
Metabolic analysis of infants with bronchopulmonary dysplasia under early nutrition therapy: An observational cohort study
To assess the amino acid and fatty acid metabolite patterns between infants with and without bronchopulmonary dysplasia in...
Protective effect of dexmedetomidine on intestinal mucosal barrier function in rats after cardiopulmonary bypass
Protective effect of dexmedetomidine on intestinal mucosal barrier function in rats after cardiopulmonary bypass
Cardiopulmonary bypass can result in damage to the intestines, leading to the occurrence of systemic inflammatory response...
Developing portable widefield fundus camera for teleophthalmology: Technical challenges and potential solutions
Developing portable widefield fundus camera for teleophthalmology: Technical challenges and potential solutions
A portable, low cost, widefield fundus camera is essential for developing affordable teleophthalmology. However, conventio...
Maternal serum-derived exosomal lactoferrin as a marker in detecting and predicting ventricular septal defect in fetuses
Maternal serum-derived exosomal lactoferrin as a marker in detecting and predicting ventricular septal defect in fetuses
Among different types of congenital heart diseases, ventricular septal defect is the most frequently diagnosed type and is...
A comprehensive overview of PPM1A: From structure to disease
A comprehensive overview of PPM1A: From structure to disease
PPM1A (magnesium-dependent phosphatase 1 A, also known as PP2Cα) is a member of the Ser/Thr protein phosphatase family. Pr...
Quantification of biomechanical properties of human corneal scar using acoustic radiation force optical coherence elastography
Quantification of biomechanical properties of human corneal scar using acoustic radiation force optical coherence elastography
Biomechanical properties of corneal scar are strongly correlated with many corneal diseases and some types of corneal surg...
Wnt signaling in biliary development, proliferation, and fibrosis
Wnt signaling in biliary development, proliferation, and fibrosis
Biliary fibrosis is an important pathological indicator of hepatobiliary damage. Cholangiocyte is the key cell type involv...
Carbon “quantum” dots for bioapplications
Carbon “quantum” dots for bioapplications
Carbon “quantum” dots or carbon dots (CDots) exploit and enhance the intrinsic photoexcited state properties and processes...
Iron-based phosphorus chelator: Risk of iron deposition and action on bone metabolism in uremic rats
Iron-based phosphorus chelator: Risk of iron deposition and action on bone metabolism in uremic rats
Phosphate chelators are frequently used in patients with chronic kidney disease (CKD). New iron-based chelators remain und...
Overall and cancer-specific survival in patients with breast Paget disease: A population-based study
Overall and cancer-specific survival in patients with breast Paget disease: A population-based study
Paget disease of the breast is an uncommon malignant tumor with an inferior outcome. Therefore, establishing nomograms to ...
Complement component 3 mutations alter the longitudinal risk of pediatric malaria and severe malarial anemia
Complement component 3 mutations alter the longitudinal risk of pediatric malaria and severe malarial anemia
Severe malarial anemia (SMA) is a leading cause of childhood morbidity and mortality in holoendemic Plasmodium falciparum ...
Barley microgreen incorporation in diet-controlled diabetes and counteracted aflatoxicosis in rats
Barley microgreen incorporation in diet-controlled diabetes and counteracted aflatoxicosis in rats
Increased environmental pollution and unhealthy lifestyle are blamed for escalated chronic diseases. Exposure to aflatoxin...
Expressing MLH1 in HCT116 cells increases cellular resistance to radiation by activating the PRKAC
Expressing MLH1 in HCT116 cells increases cellular resistance to radiation by activating the PRKAC
Mut L homolog-1 (MLH1) is a key DNA mismatch repair protein which participates in the sensitivity to DNA damaging agents. ...
Emerging technologies and their impact on regulatory science
Emerging technologies and their impact on regulatory science
There is an evolution and increasing need for the utilization of emerging cellular, molecular and in silico technologies a...
Bioinformatics analysis of an animal model of diet-induced nonalcoholic fatty liver disease with rapid progression
Bioinformatics analysis of an animal model of diet-induced nonalcoholic fatty liver disease with rapid progression
Nonalcoholic fatty liver disease (NAFLD) develops rapidly in high-fat diet (HFD) fed Mongolian gerbil (Meriones unguiculat...
Bacterial microbiota in upper respiratory tract of COVID-19 and influenza patients
Bacterial microbiota in upper respiratory tract of COVID-19 and influenza patients
The upper respiratory tract is inhabited by diverse range of commensal microbiota which plays a role in protecting the muc...
Complement factor H deficiency combined with smoking promotes retinal degeneration in a novel mouse model
Complement factor H deficiency combined with smoking promotes retinal degeneration in a novel mouse model
Age-related macular degeneration is the leading cause of blindness in the elderly. The Y402H polymorphism in complement fa...
The alleles of AGT and HIF1A gene affect the risk of hypertension in plateau residents
The alleles of AGT and HIF1A gene affect the risk of hypertension in plateau residents
Plateau essential hypertension is a common chronic harmful disease of permanent residents in plateau areas. Studies have s...
Structural analysis of SARS-Cov-2 nonstructural protein 1 polymorphisms found in the Brazilian Amazon
Structural analysis of SARS-Cov-2 nonstructural protein 1 polymorphisms found in the Brazilian Amazon
The coronavirus disease COVID-19 has been the cause of millions of deaths worldwide. Among the SARS-CoV-2 proteins, the no...
CCNB1 promotes the development of hepatocellular carcinoma by mediating DNA replication in the cell cycle
CCNB1 promotes the development of hepatocellular carcinoma by mediating DNA replication in the cell cycle
In our studies, cyclin B1 (CCNB1) mRNA and protein were overexpressed in hepatocellular carcinoma (HCC) tissues compared w...