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Loss of or decrease in CD30 expression in four patients with anaplastic large cell lymphoma after brentuximab vedotin-containing therapy
Loss of or decrease in CD30 expression in four patients with anaplastic large cell lymphoma after brentuximab vedotin-containing therapy
Brentuximab vedotin (BV), CD30 specific antibody drug conjugate, has been used to treat anaplastic large cell lymphoma (AL...
Extraskeletal chondroma of the toe in a child with DICER1 tumor predisposition syndrome: support for a dominant negative mechanism
Extraskeletal chondroma of the toe in a child with DICER1 tumor predisposition syndrome: support for a dominant negative mechanism
DICER1 tumor predisposition syndrome is a pleiotropic disorder that gives rise to various mainly pediatric-onset lesions. ...
Optimizing the management of thyroid specimens to efficiently generate whole slide images for diagnosis
Optimizing the management of thyroid specimens to efficiently generate whole slide images for diagnosis
Transition from optical to digital observation requires an additional procedure in the pathology laboratory, the scanning ...
Differentiating BRAF V600E- and RAS-like alterations in encapsulated follicular patterned tumors through histologic features: a validation study
Differentiating BRAF V600E- and RAS-like alterations in encapsulated follicular patterned tumors through histologic features: a validation study
Differentiating BRAF V600E- and RAS-altered encapsulated follicular-patterned thyroid tumors based on morphology remains c...
Myeloid sarcoma with RBM15::MRTFA (MKL1) mimicking vascular neoplasm
Myeloid sarcoma with RBM15::MRTFA (MKL1) mimicking vascular neoplasm
Extramedullary involvement of acute myeloid leukemia (AML), aka myeloid sarcoma, is a rare phenomenon in acute megakaryobl...
Exploring the histogenesis of STK11 adnexal tumour using electron microscopy
Exploring the histogenesis of STK11 adnexal tumour using electron microscopy
STK11 adnexal tumour is a recently described female genital tract tumour, usually identified in a paratubal location, ofte...
Tumor stroma ratio, tumor stroma maturity, tumor-infiltrating immune cells in relation to prognosis, and neoadjuvant therapy response in esophagogastric junction adenocarcinoma
Tumor stroma ratio, tumor stroma maturity, tumor-infiltrating immune cells in relation to prognosis, and neoadjuvant therapy response in esophagogastric junction adenocarcinoma
Accurate predictions on prognosis and neoadjuvant therapy response are crucial for esophagogastric junction adenocarcinoma...
Increased expression of CD70 in relapsed acute myeloid leukemia after hypomethylating agents
Increased expression of CD70 in relapsed acute myeloid leukemia after hypomethylating agents
Acute myeloid leukemia (AML) is the most common acute leukemia in adults. While induction chemotherapy leads to remission ...
Update on olfactory neuroblastoma
Update on olfactory neuroblastoma
Olfactory neuroblastomas are uncommon malignancies that arise from olfactory receptor cells located high in the nasal cavi...
Biphasic papillary (biphasic squamoid alveolar) renal cell carcinoma: a clinicopathologic and molecular study of 17 renal cell carcinomas including 10 papillary adenomas
Biphasic papillary (biphasic squamoid alveolar) renal cell carcinoma: a clinicopathologic and molecular study of 17 renal cell carcinomas including 10 papillary adenomas
Biphasic papillary renal cell carcinoma (synonymous with biphasic squamoid alveolar renal cell carcinoma) is considered wi...
Inflammatory/juvenile-like polyps in neurofibromatosis type 1 associated with epithelial dysplasia
Inflammatory/juvenile-like polyps in neurofibromatosis type 1 associated with epithelial dysplasia
The term “juvenile-like (inflammatory/hyperplastic) mucosal polyps” (JLIHMP) has been recently introduced to d...
Poorly differentiated thyroid carcinomas: conceptual controversy and clinical impact
Poorly differentiated thyroid carcinomas: conceptual controversy and clinical impact
Poorly differentiated thyroid carcinomas (PDTC) are rare diseases; nevertheless, they account for the majority of deaths f...
Granulation tissue-like spindle cell (sarcomatoid) carcinoma of the head and neck: a deceptively bland-looking underdiagnosed malignancy
Granulation tissue-like spindle cell (sarcomatoid) carcinoma of the head and neck: a deceptively bland-looking underdiagnosed malignancy
The diagnosis of head and neck spindle cell squamous carcinoma (SC-SCC) is often challenging. Lesions with a prominent inf...
COVID-19 in the Netherlands: lessons from a nationwide query of dutch autopsy, histology, and cytology pathological reports
COVID-19 in the Netherlands: lessons from a nationwide query of dutch autopsy, histology, and cytology pathological reports
Since the onset of the COVID-19 pandemic, autopsies have played a valuable role in understanding the pathophysiology of CO...
Correction to: Practical guidelines of the EOTTD for pathological and genetic diagnosis of hydatidiform moles
Correction to: Practical guidelines of the EOTTD for pathological and genetic diagnosis of hydatidiform moles
Department of Pathology, Cancer Biology & Epigenetics Group, Research Center of IPO Porto (CI-IPOP) / RISE@ CI-IPOP (H...
Ovarian endometrioid carcinoma with a sex cord-like pattern: a morphological, immunohistochemical, and molecular analysis
Ovarian endometrioid carcinoma with a sex cord-like pattern: a morphological, immunohistochemical, and molecular analysis
Sex cord-like endometrioid carcinoma (SCLEC) is an uncommon entity which may constitute a diagnostic challenge. This study...
Molecular diagnostics of hepatobiliary and pancreatic neoplasias
Molecular diagnostics of hepatobiliary and pancreatic neoplasias
Neoplasias of the hepatopancreatobiliary tract are growing in numbers, have the poorest prognosis of all major cancer enti...
Prevalence and interpretation of AFF immunostain of DEK::AFF2 fusion-associated papillary squamous cell carcinoma in a retrospective cohort of recurrent sinonasal papillomas
Prevalence and interpretation of AFF immunostain of DEK::AFF2 fusion-associated papillary squamous cell carcinoma in a retrospective cohort of recurrent sinonasal papillomas
DEK::AFF2 fusion-associated papillary squamous cell carcinoma is a novel entity characterized by its unique translocation ...
SATB2, CKAE1/AE3, and synaptophysin as a sensitive immunohistochemical panel for the detection of lymph node metastases of Merkel cell carcinoma
SATB2, CKAE1/AE3, and synaptophysin as a sensitive immunohistochemical panel for the detection of lymph node metastases of Merkel cell carcinoma
Histopathological evaluation of lymph nodes in Merkel cell carcinoma has become crucial in progression estimation and trea...
Correction to: HER2 copy number determination in breast cancer using the highly sensitive droplet digital PCR method
Correction to: HER2 copy number determination in breast cancer using the highly sensitive droplet digital PCR method
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
Postponing evolution: why are we choosing to ignore the need for a digital transformation in pathology?
Postponing evolution: why are we choosing to ignore the need for a digital transformation in pathology?
For some years now, practical evidence on the benefits of using whole slide images (W...
Letter to the editor on Donzel M et al. “Androgenetic/biparental mosaicism in a diploid mole-like conceptus: report of a case with triple paternal contribution”
Letter to the editor on Donzel M et al. “Androgenetic/biparental mosaicism in a diploid mole-like conceptus: report of a case with triple paternal contribution”
Donzel M, Gaillot-Durand L, Joubert M, Aziza J, Beneteau C, Mauduit C, Ploteau S, Hajri T, Bolze PA, Massardier J, Devouas...
„Rasse“ als globaler Datenstrom: Die Hamburger Anthropologie des 20. Jahrhunderts als Ausgangspunkt einer Datengeschichte der Rassifizierung
„Rasse“ als globaler Datenstrom: Die Hamburger Anthropologie des 20. Jahrhunderts als Ausgangspunkt einer Datengeschichte der Rassifizierung
Dieser Aufsatz zeigt anhand der Hamburger Anthropologie des 20. Jahrhunderts, wie historisch spezifische Aufschre...
Immunohistochemical markers as predictors of prognosis in multifocal prostate cancer
Immunohistochemical markers as predictors of prognosis in multifocal prostate cancer
The impact of tumor focality on prostate cancer (PCa) prognosis has been addressed in several studies with conflicting res...
Molecular pathology in breast disease: diagnostic, prognostic, and therapeutic tools
Molecular pathology in breast disease: diagnostic, prognostic, and therapeutic tools
Molecular testing in breast cancer gained increasing attention and importance as specific molecular results can tailor not...
HER2 copy number determination in breast cancer using the highly sensitive droplet digital PCR method
HER2 copy number determination in breast cancer using the highly sensitive droplet digital PCR method
Human epidermal growth factor receptor 2 (HER)-positive breast cancer (BC) is characterized by an aggressive clinical cour...
The practical utility of AI-assisted molecular profiling in the diagnosis and management of cancer of unknown primary: an updated review
The practical utility of AI-assisted molecular profiling in the diagnosis and management of cancer of unknown primary: an updated review
Cancer of unknown primary (CUP) presents a complex diagnostic challenge, characterized by metastatic tumors of unknown tis...
Genomic alterations and diagnosis of renal cancer
Genomic alterations and diagnosis of renal cancer
The application of molecular profiling has made substantial impact on the classification of urogenital tumors. Therefore, ...
Pathologic approach to Neonatal cholestasis with a simple scoring system for biliary atresia
Pathologic approach to Neonatal cholestasis with a simple scoring system for biliary atresia
A liver biopsy is essential for the diagnostic workup of persistent neonatal cholestasis (NC). The differential diagnosis ...
Molecular pathology as basis for timely cancer diagnosis and therapy
Molecular pathology as basis for timely cancer diagnosis and therapy
Precision and personalized therapeutics have witnessed significant advancements in technology, revolutionizing the capabil...
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