Gunne S, Heinicke U, Parnham MJ, Laux V, Zacharowski K, von Knethen A. Nrf2-A molecular target for sepsis patients in critical care. Biomolecules. 2020;10(12):E1688.

Article  Google Scholar 

Laura E, Andrew R, Waleed A, et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021. Crit Care Med. 2021;49(11):e1063–143.

Article  Google Scholar 

Li J, Hongliang W. Autophagy-dependent ferroptosis in infectious disease. J Transl Int Med. 2023;11(4):355–62.

Article  PubMed  PubMed Central  Google Scholar 

Rosadini CV, Kagan JC. Early innate immune responses to bacterial LPS. Curr Opin Immunol. 2017;44:14–9.

Article  CAS  PubMed  Google Scholar 

Cavaillon JM. Exotoxins and endotoxins: inducers of inflammatory cytokines. Toxicon. 2018;149:45–53.

Article  CAS  PubMed  Google Scholar 

Li Q, Wu C, Liu Z, Zhang H, Du Y, Liu Y, et al. Increased TLR4 expression aggravates sepsis by promoting IFN-gamma expression in CD38(-/-) mice. J Immunol Res. 2019;2019:3737890.

Article  PubMed  PubMed Central  Google Scholar 

Liu L, Sun B. Neutrophil pyroptosis: new perspectives on sepsis. Cell Mol Life Sci. 2019;76(11):2031–42.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kunze FA, Bauer M, Komuczki J, Lanzinger M, Gunasekera K, Hopp AK, et al. ARTD1 in myeloid cells controls the IL-12/18-IFN-gamma axis in a model of sterile sepsis, chronic bacterial infection, and cancer. J Immunol. 2019;202(5):1406–16.

Article  CAS  PubMed  Google Scholar 

Fan J, Xie K, Wang L, Zheng N, Yu X. Roles of inflammasomes in inflammatory kidney diseases. Mediators Inflamm. 2019;21(2019):2923072.

Google Scholar 

Zhong Z, Sanchez-Lopez E, Karin M. Autophagy, NLRP3 inflammasome and auto-inflammatory/immune diseases. Clin Exp Rheumatol. 2016;34(4 Suppl 98):12–6.

PubMed  Google Scholar 

Guo H, Callaway JB, Ting JP. Inflammasomes: mechanism of action, role in disease, and therapeutics. Nat Med. 2015;21(7):677–87.

Article  PubMed  PubMed Central  Google Scholar 

Jo EK, Kim JK, Shin DM, Sasakawa C. Molecular mechanisms regulating NLRP3 inflammasome activation. Cell Mol Immunol. 2016;13(2):148–59.

Article  CAS  PubMed  Google Scholar 

Guo HC, Jin Y, Zhi XY, Yan D, Sun SQ. NLRP3 inflammasome activation by viroporins of animal viruses. Viruses. 2015;7(7):3380–91.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hayward JA, Mathur A, Ngo C, Man SM. Cytosolic recognition of microbes and pathogens: inflammasomes in action. Microbiol Mol Biol Rev. 2018;82(4):e00015-18.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Inserra A, Rogers GB, Licinio J, Wong ML. The microbiota-inflammasome hypothesis of major depression. BioEssays. 2018;40(9): e1800027.

Article  PubMed  Google Scholar 

Malavige GN, Ogg GS. Pathogenesis of vascular leak in dengue virus infection. Immunology. 2017;151(3):261–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang C, Li Q, Ren J. Microbiota-immune interaction in the pathogenesis of gut-derived infection. Front Immunol. 2019;7(10):1873.

Article  Google Scholar 

Schnoor M, García Ponce A, Vadillo E, Pelayo R, Rossaint J, Zarbock A. Actin dynamics in the regulation of endothelial barrier functions and neutrophil recruitment during endotoxemia and sepsis. Cell Mol Life Sci. 2017;74(11):1985–97.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Haohao Z, Xueying W, Jing Z, Yixuan H, Xiumin Y, et al. Crosstalk between gut microbiota and gut resident macrophages in inflammatory bowel disease. J Transl Int Med. 2023;11(4):382–92.

Article  Google Scholar 

Kim MH, Kim H. The roles of glutamine in the intestine and its implication in intestinal diseases. Int J Mol Sci. 2017;18(5):1051.

Article  PubMed  PubMed Central  Google Scholar 

Adu-Gyamfi EA, Czika A, Gorleku PN, Ullah A, Panhwar Z, Ruan LL, et al. The involvement of cell adhesion molecules, tight junctions, and gap junctions in human placentation. Reprod Sci. 2020 Nov 4.

Cai H, Liu W, Xue Y, Shang X, Liu J, Li Z, et al. Roundabout 4 regulates blood-tumor barrier permeability through the modulation of ZO-1, occludin, and claudin-5 expression. J Neuropathol Exp Neurol. 2015;74(1):25–37.

Article  CAS  PubMed  Google Scholar 

London NR, Zhu W, Bozza FA, Smith MC, Greif DM, Sorensen LK, et al. Targeting Robo4-dependent slit signaling to survive the cytokine storm in sepsis and influenza. Sci Transl Med. 2010;2(23):23ra19.

Article  PubMed  PubMed Central  Google Scholar 

Jaouadi H, Jopling C, Bajolle F, et al. Expanding the phenome and variome of the ROBO-SLIT pathway in congenital heart defects: toward improving the genetic testing yield of CHD. J Transl Med. 2023;21(1):160–160160.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bekes I, Haunerdinger V, Sauter R, Holzheu I, Janni W, Wöckel A, et al. Slit2/Robo4 signaling: potential role of a vegf-antagonist pathway to regulate luteal permeability. Geburtshilfe Frauenheilkd. 2017;77(1):73–80.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Weng J, Zhou X, Xie H, Gao Y, Wang Z, Gong Y. Slit2/Robo4 signaling pathway modulates endothelial hyper-permeability in a two-event in vitro model of transfusion-related acute lung injury. Blood Cells Mol Dis. 2019;76:7–12.

Article  CAS  PubMed  Google Scholar 

Anand AR, Nagaraja T, Ganju RK. A novel role for Slit2/Robo1 axis in modulating HIV-1 replication in T cells. AIDS. 2011;25(17):2105–11.

Article  CAS  PubMed  Google Scholar 

Chung K, Kim K, Choi Y, An H, Lee B, Kim D, et al. The critical role played by endotoxin-induced liver autophagy in the maintenance of lipid metabolism during sepsis. Autophagy. 2017;13(7):1113–29.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yang X, Downey J, Cohen M, Housley N, Alvarez D, Audia J. The highly selective caspase-1 inhibitor VX-765 provides additive protection against myocardial infarction in rat hearts when combined with a platelet inhibitor. J Cardiovasc Pharmacol Ther. 2017;22(6):574–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yoseph BP, Klingensmith NJ, Liang Z, Breed ER, Burd EM, Mittal R, et al. Mechanisms of intestinal barrier dysfunction in sepsis. Shock. 2016;46(1):52–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kumar M, Leon Coria A, Cornick S, Petri B, Mayengbam S, Jijon HB, et al. Increased intestinal permeability exacerbates sepsis through reduced hepatic SCD-1 activity and dysregulated iron recycling. Nat Commun. 2020;11(1):483.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cohen J, Vincent JL, Adhikari NK, Machado FR, Angus DC, Calandra T, et al. Sepsis: a roadmap for future research. Lancet Infect Dis. 2015;15(5):581–614.

Article  PubMed  Google Scholar