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Unveiling the Therapeutic Potential of Jiawei Jianpi Huoyu Formula in Ulcerative Colitis: A Multi-Strategies and Experimental Study Integrating Network Pharmacology, Machine Learning, and Mendelian Randomization
Unveiling the Therapeutic Potential of Jiawei Jianpi Huoyu Formula in Ulcerative Colitis: A Multi-Strategies and Experimental Study Integrating Network Pharmacology, Machine Learning, and Mendelian Randomization
We clarify the specific mechanisms by which JJHF alleviates symptoms of UC, and provide a scientific foundation for promot...
Comprehensive Analysis of Ferroptosis Markers in Lupus Nephritis Based on Bioinformatics Analysis and Experimental Validation
Comprehensive Analysis of Ferroptosis Markers in Lupus Nephritis Based on Bioinformatics Analysis and Experimental Validation
Completing comprehensive analysis of ferroptosis markers in lupus nephritis based on bioinformatics analysis and experimen...
A Machine Learning Model Integrating Preoperative Blood-Based Indices for Early and Noninvasive Detection of Endometrial Cancer
A Machine Learning Model Integrating Preoperative Blood-Based Indices for Early and Noninvasive Detection of Endometrial Cancer
To develop a non-invasive, preoperative tool to predict EC risk using machine learning techniques.
Mechanistic Perspectives on Radiation-Induced Skin Injury and the Protective Effects of Berberine
Mechanistic Perspectives on Radiation-Induced Skin Injury and the Protective Effects of Berberine
Studying the mechanistic Perspectives on Radiation-Induced Skin Injury and the Protective Effects of Berberine. Read more
Bioinformatics Analysis and Identification of Ferroptosis-Related Gene TIMP1 as a Potential Biomarker of Asthma
Bioinformatics Analysis and Identification of Ferroptosis-Related Gene TIMP1 as a Potential Biomarker of Asthma
Identifying ferroptosis-related genes in asthmatic airway epithelial cells, providing potential therapeutic targets for ma...
Downregulated RSAD2 Attenuates the Apoptosis of LPS-Stimulated RAW264.7 via NF-κB Signaling Pathway
Downregulated RSAD2 Attenuates the Apoptosis of LPS-Stimulated RAW264.7 via NF-κB Signaling Pathway
RSAD2 knockdown alleviated LPS-induced apoptosis in RAW264.7 macrophages by suppressing the NF-κB signaling pathway,...
Digital PCR-Based Assessment of Piwi-RNA PIR35982 as a Supporting Biomarker in Rheumatoid Arthritis
Digital PCR-Based Assessment of Piwi-RNA PIR35982 as a Supporting Biomarker in Rheumatoid Arthritis
Identifying piwi-RNAs whose expression may be associated with the severity rheumatoid arthritis.
Role of Interleukin-6 in Rheumatoid Arthritis-Associated Interstitial Lung Disease: Focus on the JAK/STAT Pathway and Macrophage Polarization
Role of Interleukin-6 in Rheumatoid Arthritis-Associated Interstitial Lung Disease: Focus on the JAK/STAT Pathway and Macrophage Polarization
This review elucidates the molecular mechanisms by which IL-6 contributes to rheumatoid arthritis-associated interstitial ...
Mechanism of Lipi Jiangzhuo Decoction in Improving Metabolic Dysfunction-Associated Steatohepatitis Through the PERK/PINK1/GPx4 Pathway
Mechanism of Lipi Jiangzhuo Decoction in Improving Metabolic Dysfunction-Associated Steatohepatitis Through the PERK/PINK1/GPx4 Pathway
This study aims to elucidate the molecular mechanism by which LPJZD improves MASH and promote research of TCM formulas
Oligoclonal Bands as Predictors of Disease Severity and Prognosis in Anti-NMDAR Encephalitis
Oligoclonal Bands as Predictors of Disease Severity and Prognosis in Anti-NMDAR Encephalitis
This study explored the association between OCBs and clinical manifestations, disease severity, and prognosis in patients ...
Prognostic Nutritional Index is A Useful Predictive Marker for Morbidity and Mortality in Surgery for Perforated Peptic Ulcer
Prognostic Nutritional Index is A Useful Predictive Marker for Morbidity and Mortality in Surgery for Perforated Peptic Ulcer
To assess the performance of PNI in predicting morbidity and mortality among patients undergoing surgery for PPU.
Exploring the Role of Peroxisome-Related Processes and Key Marker Genes in Sepsis: Insights Into Immune Dynamics and Therapeutic Potential
Exploring the Role of Peroxisome-Related Processes and Key Marker Genes in Sepsis: Insights Into Immune Dynamics and Therapeutic Potential
Performing a bioinformatic analysis of DPGs in sepsis, utilizing advanced computational techniques to uncover potential bi...
Single-Cell RNA Sequencing Reveals Pericytes Acquire a Fibrotic Phenotype and Promote Mesenteric Adipose Tissue Fibrosis in Crohn’s Disease
Single-Cell RNA Sequencing Reveals Pericytes Acquire a Fibrotic Phenotype and Promote Mesenteric Adipose Tissue Fibrosis in Crohn’s Disease
Elucidating the cellular origins of Creeping fat (CF) fibrosis and the involvement of pericytes in Crohn’s disease
Bone Marrow Mesenchymal Stem Cells Can Prevent Pancreatic Fibrosis in Mice with Chronic Pancreatitis by Inhibiting the Activation of Pancreatic Stellate Cells
Bone Marrow Mesenchymal Stem Cells Can Prevent Pancreatic Fibrosis in Mice with Chronic Pancreatitis by Inhibiting the Activation of Pancreatic Stellate Cells
Bone Marrow Mesenchymal Stem Cells Can Prevent Pancreatic Fibrosis in Mice with Chronic Pancreatitis by Inhibiting the Act...
Effectiveness of Combining Thoracic Paravertebral Nerve Block and Serratus Anterior Plane Block in Non-Intubated Spontaneous-Ventilation Video-Assisted Thoracoscopic Surgery: A Retrospective Case-Control Study
Effectiveness of Combining Thoracic Paravertebral Nerve Block and Serratus Anterior Plane Block in Non-Intubated Spontaneous-Ventilation Video-Assisted Thoracoscopic Surgery: A Retrospective Case-Control Study
These findings advocate for broader adoption of combined nerve block techniques to enhance patient outcomes in video-assis...
Immune Signatures Distinguish Pure and Mixed Sepsis in Critical COVID-19: A Retrospective Cohort Study
Immune Signatures Distinguish Pure and Mixed Sepsis in Critical COVID-19: A Retrospective Cohort Study
Our goal is to improve outcomes by translating immune phenotyping into individualized treatment strategies across diverse ...
Fecal Calprotectin Combined with Blood Inflammatory Biomarkers Enhances Diagnostic Evaluation and Supports Mucosal Healing Assessment in Pediatric Crohn’s Disease
Fecal Calprotectin Combined with Blood Inflammatory Biomarkers Enhances Diagnostic Evaluation and Supports Mucosal Healing Assessment in Pediatric Crohn’s Disease
We evaluate the diagnostic and mucosal healing assessment value of FC and composite biomarker index incorporating systemic...
ALDH2 Ameliorates Acute Gouty Arthritis Through Inhibiting NLRP3 Inflammasome and Pyroptosis by Nrf2/ROS Pathway
ALDH2 Ameliorates Acute Gouty Arthritis Through Inhibiting NLRP3 Inflammasome and Pyroptosis by Nrf2/ROS Pathway
we hypothesized that ALDH2 may possess the capacity to inhibit MSU crystal-induced activation of the NLRP3 inflammasome an...
Risk Prediction of Severe Complications Caused by Hymenoptera Insect Stings: Development and Validation of a Nomogram Mode
Risk Prediction of Severe Complications Caused by Hymenoptera Insect Stings: Development and Validation of a Nomogram Mode
Developing a universal early risk prediction tool for Hymenoptera Insect Stings, helping frontline providers optimize high...
Rhoifolin Attenuates DSS-Induced Colitis in Mice by Modulating Gut Microbiota and Restoring Th17/Treg Balance
Rhoifolin Attenuates DSS-Induced Colitis in Mice by Modulating Gut Microbiota and Restoring Th17/Treg Balance
the present study aimed to investigate the impact of ROF administration on the gut microbiome and Th17/Treg cell balance i...
Regulated Cell Death of Alveolar Macrophages in Acute Lung Inflammation: Current Knowledge and Perspectives
Regulated Cell Death of Alveolar Macrophages in Acute Lung Inflammation: Current Knowledge and Perspectives
Focus on AMs role in maintaining healthy lung homeostasis and how they affect inflammatory response and tissue repair via ...
Unveiling Key Biomarkers and Mechanisms in Septic Cardiomyopathy: A Comprehensive Transcriptome Analysis
Unveiling Key Biomarkers and Mechanisms in Septic Cardiomyopathy: A Comprehensive Transcriptome Analysis
To enhance our understanding of SCM's underlying mechanisms and might pave the way for novel therapeutic strategies to imp...
Astragalus Polysaccharide Mitigates Rhabdomyolysis-Induced Acute Kidney Injury via Inhibition of M1 Macrophage Polarization and the cGAS-STING Pathway
Astragalus Polysaccharide Mitigates Rhabdomyolysis-Induced Acute Kidney Injury via Inhibition of M1 Macrophage Polarization and the cGAS-STING Pathway
Impact of astragalus polysaccharides on rhabdomyolysis induced acute kidney injury, association with macrophage M1 polariz...
Nomogram Based on Immune-Inflammatory Score and Classical Clinicopathological Parameters for Predicting the Recurrence of Endometrial Carcinoma: A Large, Multi-Center Retrospective Study
Nomogram Based on Immune-Inflammatory Score and Classical Clinicopathological Parameters for Predicting the Recurrence of Endometrial Carcinoma: A Large, Multi-Center Retrospective Study
Developing a clinicopathological-inflammatory parameters-based nomogram to accurately predict the postoperative recurrence...
Macrophage Infiltration Correlated with IFI16, EGR1 and MX1 Expression in Renal Tubular Epithelial Cells Within Lupus Nephritis-Associated Tubulointerstitial Injury via Bioinformatics Analysis
Macrophage Infiltration Correlated with IFI16, EGR1 and MX1 Expression in Renal Tubular Epithelial Cells Within Lupus Nephritis-Associated Tubulointerstitial Injury via Bioinformatics Analysis
To investigate potential new diagnostic biomarkers and immune infiltration characteristics associated with tubulointerstit...
Identifying Key Prognostic Indicators for Relapse and Chronic Epilepsy in Autoimmune Encephalitis: Insights from a Multicenter Retrospective Study
Identifying Key Prognostic Indicators for Relapse and Chronic Epilepsy in Autoimmune Encephalitis: Insights from a Multicenter Retrospective Study
Investigating clinical factors associated with encephalitis relapse, chronic epilepsy development and the effectiveness of...
Serum Globulin and Albumin-to-Globulin Ratio are Associated with Diabetic Kidney Disease but Not Diabetic Retinopathy in Type 2 Diabetes Mellitus Patients: A Cross-Sectional Study
Serum Globulin and Albumin-to-Globulin Ratio are Associated with Diabetic Kidney Disease but Not Diabetic Retinopathy in Type 2 Diabetes Mellitus Patients: A Cross-Sectional Study
Exploring the association of globulin and albumin-to-globulin ratio with diabetic kidney disease and diabetic retinopathy ...
Single-Cell Sequencing and Machine Learning Integration to Identify Candidate Biomarkers in Psoriasis: INSIG1
Single-Cell Sequencing and Machine Learning Integration to Identify Candidate Biomarkers in Psoriasis: INSIG1
Using Single-Cell Sequencing and Machine Learning Integration to Identify Candidate Biomarkers in Psoriasis: INSIG1 and es...
Exploring the Regulatory Mechanism of CXCL16 Molecule-Related Antigen Presentation Using lncRNA-mRNA Co-Expression Network Analysis
Exploring the Regulatory Mechanism of CXCL16 Molecule-Related Antigen Presentation Using lncRNA-mRNA Co-Expression Network Analysis
Investigating the regulatory mechanism of CXCL16 molecule-related Aspergillus fumigatus extract-induced antigen presentati...
Human Herpesvirus 6A Infection-Associated Acute Anterior Uveitis
Human Herpesvirus 6A Infection-Associated Acute Anterior Uveitis
This study, for the first time, reports a case of arterior uveitis with HHV-6A as the probable causative agent in a 37-yea...
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