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Beyond skin deep: total-body positron emission tomography to illuminate systemic inflammation in psoriatic arthritis
Psoriatic arthritis (PsA) represents a paradigmatic example of an immune-mediated inflammatory condition, where dysregulat...
Concept of dual immune inhibitors for the treatment of drug-resistant psoriatic disease
Biologics have transformed the management of immune-mediated diseases, including psoriasis and psoriatic arthritis (PsA), ...
Moving beyond the Janus kinase signaling kinases in the pathogenesis and treatment of psoriasis and psoriatic arthritis
Psoriatic disease encompasses psoriasis and psoriatic arthritis. It is a chronic, progressive condition and leads to irrev...
Editorial overview: Transfusion is not a miracle, but an extraordinary fact and an immunological impossibility
Olivier Garraud, MD PhD has had a long-term experience in blood banking, blood transfusion medicine, and hemovigilance act...
Extracellular vesicle impact on immunity following blood transfusion
Recent FindingsEVs impact transfusion outcomes by modulating immune and inflammatory responses. Acting as lipid mediators ...
Inflammation induced by lipid mediators and protein from transfusion products
Transfusions of whole blood, plasma, red blood cell (RBC) concentrates, and platelet concentrates (PCs) are critical for t...
Development and consequences of red blood cell autoantibodies: warm autoimmune hemolytic anemia
Autoimmune hemolytic anemia (AIHA) is a rare disorder caused by loss of tolerance to red blood cell (RBC) antigens, leadin...
Corrigendum to “A unifying hypothesis on the central role of reactive oxygen species in bacterial pathogenesis and host defense in C. elegans” [Curr Opin Immunol 2021, 68:9–20. COIMMU_2005]
Volume 95, August 2025, 102598Author links open overlay panelDebanjan Goswamy, Javier E IrazoquiShow morePrevious article ...
Mapping economic outcomes: how biosimilars enhance access to health systems in Latin America and the Caribbean
Biological therapy has revolutionized the treatment landscape of complex and chronic conditions, including autoimmune dise...
Can we cure autoimmune hepatitis?
Autoimmune hepatitis (AIH) is an organ-specific autoimmune disease that occurs in individuals of all age groups. Although ...
HLA-B27 as a potential target for the cure of axial spondyloarthritis
Volume 96, October 2025, 102611Author links open overlay panel, , , Axial spondyloarthritis (axSpA) manifests with inflamm...
Primary sclerosing cholangitis: what is new in the therapeutic landscape
Primary sclerosing cholangitis (PSC) is a rare chronic cholestatic liver disease characterized by progressive inflammation...
Can we cure vasculitis?
Volume 96, October 2025, 102618Author links open overlay panel, , As with all autoimmune diseases, antineutrophil cytoplas...
Insights into platelet post-transfusional human leukocyte antigen I immunization
Since its description, the human leukocyte antigen (HLA) system has been intricately linked to transfusion. In 1952, Jean ...
Immunological complications of blood transfusion: current insights and advances
Blood transfusion remains an integral part of patient management in current medical practice and plays a critical role acr...
Metabolic regulation of the immune cell in psoriasis: mechanisms and interventions
Psoriasis is increasingly recognized as a metabolically regulated inflammatory skin disease. Aberrant glycolysis, oxidativ...
Neuroimmune mechanisms of neuropsychiatric systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is an incurable autoimmune disease characterized by inflammation manifesting in multior...
The impact of viral evolution on vaccine development for SARS-CoV-2
Volume 96, October 2025, 102612Author links open overlay panel, , In order to stay circulating in the human population ove...
Friend or foe? — Janus Langerhans cells in skin immunity and promising clinical application
As the largest organ of the human body, the skin functions as the primary immunological interface with the external enviro...
Complement system modulation in age-related macular degeneration: navigating failures, building future successes
Volume 96, October 2025, 102616Author links open overlay panel, , Age-related macular degeneration (AMD) is a leading caus...
Role of allergen immunotherapy and biologics in allergic diseases
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Metabolic requirements of type 2 lymphocytes in allergic disease
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Epithelial-immune interactions govern type 2 immunity at barrier surfaces
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Mechanisms and risk factors for perinatal allergic disease
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Decoding the neuroimmune axis in the atopic march: mechanisms and implications
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Metabolic footprint and logic through the T cell life cycle
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Eating for immunity: how diet shapes our defenses
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Fuelling B cells: dynamic regulation of B cell metabolism
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Immunometabolic regulation of germinal centers and its implications for aging
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Carbohydrate metabolism in supporting and regulating neutrophil effector functions
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