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Roles for Siglec-glycan interactions in regulating immune cells
Volume 77, March 2025, 101925Author links open overlay panel, , , Highlights•Siglec-ligand and expression table.•Siglecs i...
Decoding the multifaceted roles of galectins in self-defense
In this review, we aim to explore the multifaceted roles of galectins in host defense from a broader perspective, particul...
The complement system in clinical oncology: Applications, limitations and challenges
Volume 77, March 2025, 101921Author links open overlay panel, , AbstractThe complement system, a key component of innate i...
Enhancing complement activation by therapeutic anti-tumor antibodies: Mechanisms, strategies, and engineering approaches
The complement system plays an integral role in both innate and adaptive immune responses. Beyond its protective function ...
The role of the complement system in the response to cytotoxic therapy
Volume 77, March 2025, 101927Author links open overlay panel, , , , AbstractThe complement system is increasingly recognis...
Beyond the Norm: The emerging interplay of complement system and extracellular matrix in the tumor microenvironment
Volume 77, March 2025, 101929Author links open overlay panel, , Highlights•The complement system exerts a “double-edged sw...
Complement regulators as novel targets for anti-cancer therapy: A comprehensive review
Cancer is a devastating disease and remains a significant public health issue globally [1]. Although cancer is fundamental...
Celiac disease, non-celiac wheat sensitivity, wheat allergy – clinical and diagnostic aspects
Volume 77, March 2025, 101930Author links open overlay panel, AbstractIn recent years, wheat- and gluten-free diets have i...
Neurogenic inflammation and itch in barrier tissues
Maintenance of organismal health and survival requires integrated multi-cellular networks that sense and resist harmful th...
Variable domain glycosylation as a marker and modulator of immune responses: Insights into autoimmunity and B-cell malignancies
Volume 78, June 2025, 101946Author links open overlay panel, , , , , Highlights•Increased variable domain glycosylation (V...
Complement and the hallmarks of cancer
The hallmarks of cancer are a set of traits that normal cells acquire during their transformation into malignancy. Among t...
Differential immune responses behind different celiac disease manifestations
Celiac disease (CeD) is a common immune-mediated disorder, with a global prevalence of 1–2 % affecting individuals with a ...
Neuroimmune interactions between itch neurons and skin microbes
Itch (or pruritus) refers to the unpleasant sensation that results in the innate behavior of scratching [1]. Most itch cas...
Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD): Insights into pathogenesis and biomarkers of prognosis
Volume 78, June 2025, 101944Author links open overlay panel, AbstractMOG antibody-associated disease (MOGAD), an inflammat...
The immunological processes behind aquaporin 4-antibody seropositive neuromyelitis optica spectrum disorders
Volume 78, June 2025, 101945Author links open overlay panel, , AbstractEver since the discovery of pathogenic aquaporin 4-...
The role of the adaptive immune system in the initiation and persistence of multiple sclerosis
Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the central nervous system (CNS) in which complex net...
Interferon regulatory factor 3 beyond innate immunity: Regulation in obesity and metabolic disorders
Interferon regulatory factor 3 (IRF3) is a transcription factor known primarily for its role in antiviral immunity via reg...
The world’s largest experiment in human immunology
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Siglecs as modulators of macrophage phenotype and function
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The role of glycans in health and disease: Regulators of the interaction between gut microbiota and host immune system
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High-throughput N-glycan analysis in aging and inflammaging: State of the art and future directions
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Systems analysis of innate and adaptive immunity in Long COVID
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Systems biology of B cells in COVID-19
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Introduction to the special issue: B cells in cancer immunosurveillance
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B cell clonality in cancer
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The origins, manifestations, and potential treatments of allergic disorders
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Introduction to the Special Issue: Pyroptosis in Immunity and Inflammation
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Durability of immune responses to SARS-CoV-2 infection and vaccination
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Early life microbiome influences on development of the mucosal innate immune system
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To die or not to die: Gasdermins in intestinal health and disease
To die or not to die: Gasdermins in intestinal health and disease
The first member of the gasdermin family was identified in the upper gastrointestinal tract in 2000 [1]. Up until now, the...
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