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Letter to the Editor Regarding “Antibody Production after COVID-19 Vaccination in Patients with Inborn Errors of Immunity”
Dear Editor I am writing in response to the recently published study titled "Antibody Production after COVID-19 Vacc...
MicroRNA-150 Deletion Reduces the Occurrence and Severity of Rheumatoid Arthritis by Inhibiting IL-17
Background: Understanding the effects of epigenetic factors on the pathogenesis of rheumatoid arthritis (RA) is important ...
Abnormal Changes in IL-13 and IL-17A Serum Levels in Children with Adenovirus Pneumonia and their Diagnostic Value
Background: Human adenovirus (HAdV) is an enveloped icosahedral DNA virus. HAdV infection can lead to immune system damage...
IL-27 Levels in Bronchoalveolar Lavage Fluid in Children with Post-infectious Bronchiolitis Obliterans
Background: Pulmonary neutrophils may play a crucial role in the development of bronchiolitis obliterans (BO) following me...
Serum Interleukin-38 and Tumor-Infiltrating Lymphocytes in Primary Brain Tumors
Background: Tumor-infiltrating lymphocytes (TILs) and brain stromal cells produce immunosuppressive cytokines, contributin...
Intervention with ICOSL Antibodies Alleviates Inflammatory Infiltrations in Mice with Neutrophilic Asthma
Background: Neutrophilic asthma is characterized by the predominant infiltration of neutrophils in airway inflammation.Obj...
Sulforaphane Regulates Macrophage M1/M2 Polarization to Attenuate Macrophage-induced Caco-2 Cell Injury in an Inflammatory Environment
Background: The imbalance between M1 and M2 macrophage activation is closely associated with the pathogenesis of inflammat...
Immunohistochemical Evaluation of NKP46 Receptor Expression and the Number of NK Cells in the Endometrium of Patients with Endometriosis
Background: Endometriosis is a medical condition that can cause infertility in women. Women with endometriosis experience ...
The Ratio of Peripheral Blood Natural Killer Cells is not a Solid Surrogate Immune Index in Unexplained Recurrent Miscarriage
Background: Immunotherapies targeting peripheral natural killer (pbNK) cells in unexplained recurrent miscarriage (uRM) re...
Comparative Immunogenicity and Neutralization Potency of Four Approved COVID-19 Vaccines in BALB/c Mice
Background: Since the outbreak of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), several vaccine ...
Human Umbilical Cord Mesenchymal Stem Cells and Their Extracellular Vesicles Modulate Pro- and Anti-Inflammatory Cytokines in Ligature-induced Periodontitis
Background: Periodontitis is a persistent inflammatory condition that impacts the tissues supporting the teeth, ultimately...
Evaluation of mRNA Expressions of TOX and NR4As in CD8+ T cells in Acute Leukemia
Background: Thymocyte selection-associated high mobility group box protein (TOX) and members of the nuclear receptor 4A (N...
Rescue of HLH with T and B Lymphocyte Involvement Due to Epstein-Barr Virus by PD-1 Inhibitor/Ruxolitinib and Rituximab Combination Regimens: A Case Report
Hemophagocytic lymphohistiocytosis (HLH) is a fatal clinical syndrome. The most common cause of secondary HLH is Epstein-B...
High-free Fatty Acid Treatment Induced Anti-inflammatory Changes in a Natural Killer (NK) Cell Line
Background: Natural killer (NK) cells play a role in the pathogenesis of various metabolic diseases related to obesity. Wh...
Antibody Production After COVID-19 Vaccination in Patients with Inborn Errors of Immunity
Background: Few studies have evaluated COVID-19 vaccine efficacy in patients with Inborn errors of immunity (IEI).Objectiv...
Behaviors of Human T cells in SARS-CoV-2 Infection: Lessons and Tips
Cell-mediated immunity (CMI) is crucial in controlling the highly aggressive and progressive SARS-CoV-2 infection. Despite...
Elevated HSP70 and HSP90 as Predictive Markers of Immune Activation and Lung Injury in SARS-COV-2 Disease
Background: Heat shock proteins (HSPs) are involved in innate and adaptive immune responses, especially inflammatory respo...
Neutrophil Extracellular Traps Formation and Citrullinated Histones 3 Levels in Patients with Kawasaki Disease
Background: Kawasaki disease (KD) is a vasculitis associated with vascular injury and autoimmune response. Inflammatory fa...
Senescent CD153+ T Lymphocytes Increase in the Peripheral Blood of Patients with Thromboangiitis Obliterans
Background: Buerger’s disease, also known as Thromboangiitis Obliterans (TAO), is a progressive, inflammatory vascular dis...
Vol 20, Supplementary Issue, 16th International Congress of Immunology and Allergy
We are delighted to share the Abstract Book of the "16th International Congress of Immunology and Allergy". The ...
IJI, Vol 20, Supplementary Issue, 16th International Congress of Immunology and Allergy
We are delighted to share the Abstract Book of the "16th International Congress of Immunology and Allergy". The ...
Effects of Blocking NLRP3 Inflammasome on Type II Innate Lymphoid Cell Response in Allergic Rhinitis
Background: Type 2 innate lymphoid cells (ILC2s) and NLRP3 inflammasome are related to allergic and inflammatory responses...
Implications of Complement Imbalance in COVID-19: A Molecular Mechanistic Discussion on the Importance of Complement Balance
Two central questions in COVID-19 treatment which should be considered are: “How does the imbalance of the complement syst...
Angiopoietin-like 4 (ANGPTL4) Suppression Ameliorates Lupus Nephritis in MRL/lpr Mice by Inactivating NLRP3 Inflammasome and Inhibiting Inflammatory Response
Background: Lupus nephritis (LN) refers to the injury caused by systemic lupus erythematosus (SLE) involving the kidneys. ...
Impact of Echinococcus granulosus Antigens on Monocyte Development and Dendritic Cell Differentiation
Background: Different subtypes of dendritic cells (DCs) can induce different types of immune responses. Our previous study...
CD39 Expression in Peripheral T Cells is Associated with Clinicopathological Characteristics in Patients with Cervical Cancer
Background: CD39 is an inhibitory checkpoint exerting rate-limiting effects on the ATP-adenosine pathway. It can be target...
SPIB Knockdown Inhibits the Immune Escape of Ovarian Cancer Cells by Reducing PD-L1 (CD274) Expression and Inactivating the JAK/STAT Pathway
Background: Spi-B transcription factor (SPIB) is an E-twenty-six (ETS) transcription factor associated with tumor immunity...
Synthesized Anti-HER2 Trastuzumab-MCC-DM1 Conjugate: An Evaluation of Efficacy and Cytotoxicity
Background: Trastuzumab is a humanized monoclonal antibody that targets site-specifically human epidermal growth factor-2 ...
Increased Serum Levels of IL-1β after Ischemic Stroke are Inversely Associated with Vitamin D
Background: The initial inflammatory reaction starts following occlusion in ischemic stroke (IS). Interleukin-1β (IL-1β) i...
Evaluation of SARS-CoV-2 Specific Antibodies in Recovered Patients by Different ELISA Kits
Background: The coronavirus disease 2019 (COVID-19) was first reported in December 2019 in Wuhan, Hubei Province of China....
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