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P2RX7 gene variants associate with altered inflammasome assembly and reduced pyroptosis in chronic nonbacterial osteomyelitis (CNO)
P2RX7 gene variants associate with altered inflammasome assembly and reduced pyroptosis in chronic nonbacterial osteomyelitis (CNO)
Chronic nonbacterial osteomyelitis (CNO), an autoinflammatory bone disease primarily affecting children, can cause pain, h...
miR-146a and miR-146b regulate the expression of ICAM-1 in giant cell arteritis
miR-146a and miR-146b regulate the expression of ICAM-1 in giant cell arteritis
Giant cell arteritis (GCA) is a chronic inflammatory disease that affects large and medium-sized arteries. It is the most ...
Autoimmune diseases and female-specific cancer risk: A systematic review and meta-analysis
Autoimmune diseases and female-specific cancer risk: A systematic review and meta-analysis
Volume 144, April 2024, 103187Author links open overlay panel, , Highlights•Patients with rheumatoid arthritis show a redu...
Impact of muscle biopsy on the clinical decision-making process in patients with suspected idiopathic inflammatory myopathy
Impact of muscle biopsy on the clinical decision-making process in patients with suspected idiopathic inflammatory myopathy
BackgroundThe significance of muscle biopsy as a diagnostic tool in idiopathic inflammatory myopathies (IIM) remains elusi...
T cell-mediated skin-brain axis: Bridging the gap between psoriasis and psychiatric comorbidities
T cell-mediated skin-brain axis: Bridging the gap between psoriasis and psychiatric comorbidities
Psoriasis represents a chronic inflammatory skin disorder and etiologically results from immune system dysregulation. Acro...
Modulation of PKM2 inhibits follicular helper T cell differentiation and ameliorates inflammation in lupus-prone mice
Modulation of PKM2 inhibits follicular helper T cell differentiation and ameliorates inflammation in lupus-prone mice
The growth, survival, and performance of immune effector functions of immune cells are closely linked to metabolism, and i...
Ectopic CD4+ T cells in choroid plexus mediate neuropsychiatric lupus symptoms in mice via interferon-γ induced microglia activation
Ectopic CD4+ T cells in choroid plexus mediate neuropsychiatric lupus symptoms in mice via interferon-γ induced microglia activation
Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by the involvement of multiple organs [1]...
CADHERIN-11 regulation of myeloid phagocytes and autoimmune inflammation in murine lupus
CADHERIN-11 regulation of myeloid phagocytes and autoimmune inflammation in murine lupus
Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by autoantibody production, inflammation,...