Papillary renal neoplasm with reverse polarity has low frequency of alterations in chromosomes 7, 17, and Y

Al-Obaidy KI, Eble JN, Cheng L, Williamson SR, Sakr WA, Gupta N et al (2019) Papillary renal neoplasm with reverse polarity: a morphologic, immunohistochemical, and molecular study. Am J Surg Pathol 43:1099–1111

Article  PubMed  Google Scholar 

Al-Obaidy KI, Eble JN, Nassiri M, Cheng L, Eldomery MK, Williamson SR et al (2020) Recurrent KRAS mutations in papillary renal neoplasm with reverse polarity. Mod Pathol 33:1157–1164

Article  CAS  PubMed  Google Scholar 

Kim SS, Cho YM, Kim GH, Kee KH, Kim HS, Kim KM et al (2020) Recurrent KRAS mutations identified in papillary renal neoplasm with reverse polarity—a comparative study with papillary renal cell carcinoma. Mod Pathol 33:690–699

Article  CAS  PubMed  Google Scholar 

Tong K, Zhu W, Fu H, Cao F, Wang S, Zhou W et al (2020) Frequent KRAS mutations in oncocytic papillary renal neoplasm with inverted nuclei. Histopathology 76:1071–1083

Article  Google Scholar 

Zhou L, Xu J, Wang S, Yang X, Li C, Zhou J et al (2020) Papillary renal neoplasm with reverse polarity: a clinicopathologic study of 7 cases. Int J Surg Pathol 28:728–734

Article  PubMed  Google Scholar 

Chang HY, Hang JF, Wu CY, Lin TP, Chung HJ, Chang YH et al (2021) Clinicopathological and molecular characterization of papillary renal neoplasm with reverse polarity and its renal papillary adenoma analogue. Histopathology 78:1019–1031

Article  PubMed  Google Scholar 

Kiyozawa D, Kohashi K, Takamatsu D, Yamamoto T, Eto M, Iwasaki T et al (2021) Morphological, immunohistochemical, and genomic analyses of papillary renal neoplasm with reverse polarity. Hum Pathol 112:48–58

Article  CAS  PubMed  Google Scholar 

Wei S, Kutikov A, Patchefsky AS, Flieder DB, Talarchek JN, Al-Saleem T et al (2022) Papillary renal neoplasm with reverse polarity is often cystic: report of 7 cases and review of 93 cases in the literature. Am J Surg Pathol 46:336–343

Article  PubMed  Google Scholar 

Al-Obaidy KI, Saleeb RM, Trpkov K, Williamson SR, Sangoi AR, Nassiri M et al (2022) Recurrent KRAS mutations are early events in the development of papillary renal neoplasm with reverse polarity. Mod Pathol 35:1279–1286

Article  CAS  PubMed  Google Scholar 

Liu Y, Zhang H, Li X, Wang S, Zhang Y, Zhang X et al (2022) Papillary renal neoplasm with reverse polarity with a favorable prognosis should be separated from papillary renal cell carcinoma. Hum Pathol 127:78–85

Article  CAS  PubMed  Google Scholar 

Shen M, Yin X, Bai Y, Zhang H, Ru G, He X et al (2022) Papillary renal neoplasm with reverse polarity: a clinicopathological and molecular genetic characterization of 16 cases with expanding the morphologic spectrum and further support for a novel entity. Front Oncol 12:930296

Article  PubMed  PubMed Central  Google Scholar 

Wang T, Ding X, Huang X, Ye J, Li H, Cao S et al (2022) Papillary renal neoplasm with reverse polarity-a comparative study with CCPRCC, OPRCC, and PRCC1. Hum Pathol 129:60–70

Article  CAS  PubMed  Google Scholar 

Yang T, Kang E, Zhang L, Zhuang J, Li Y, Jiang Y et al (2022) Papillary renal neoplasm with reverse polarity may be a novel renal cell tumor entity with low malignant potential. Diagn Pathol 17:66

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nova-Camacho LM, Martin-Arruti M, Ruiz Díaz I, Panizo-Santos Á (2023) Papillary renal neoplasm with reverse polarity: a clinical, pathologic, and molecular study of 8 renal tumors from a single institution. Arch Pathol Lab Med 147:692–700

Article  PubMed  Google Scholar 

Williamson SR, Hartmann A, Martignoni G, Hes O, Rioux-Leclercq NC, Saleeb RM (2022) Papillary renal cell carcinoma. In WHO Classification of Tumours Editorial Board (eds) World Health Organization classification of tumours of the urinary system and male genital organs. 5th ed. IARC Press, Lyon

Trpkov K, Hes O, Williamson SR, Adeniran AJ, Agaimy A, Alaghehbandan R et al (2021) New developments in existing WHO entities and evolving molecular concepts: the Genitourinary Pathology Society (GUPS) update on renal neoplasia. Mod Pathol 34:1392–1424

Article  PubMed  Google Scholar 

Hes O, Síma R, Nemcová J, Hora M, Bulimbasic S, Kazakov DV et al (2008) End-stage kidney disease: gains of chromosomes 7 and 17 and loss of Y chromosome in non-neoplastic tissue. Virchows Arch 453:313–319

Article  PubMed  Google Scholar 

Brunelli M, Eble JN, Zhang S, Martignoni G, Cheng L (2003) Gains of chromosomes 7, 17, 12, 16, and 20 and loss of Y occur early in the evolution of papillary renal cell neoplasia: a fluorescent in situ hybridization study. Mod Pathol 16:1053–1059

Article  PubMed  Google Scholar 

Denize T, Just PA, Sibony M, Blons H, Timsit MO, Drossart T et al (2021) MET alterations in biphasic squamoid alveolar papillary renal cell carcinomas and clinicopathological features. Mod Pathol 34:647–659

Article  CAS  PubMed  Google Scholar 

Yin X, Zhang T, Su X, Ji Y, Ye P, Fu H et al (2015) Relationships between chromosome 7 gain, MET gene copy number increase and MET protein overexpression in Chinese papillary renal cell carcinoma patients. PLoS One 10:e0143468

Article  PubMed  PubMed Central  Google Scholar 

Pitra T, Pivovarcikova K, Alaghehbandan R, Hes O (2019) Chromosomal numerical aberration pattern in papillary renal cell carcinoma: review article. Ann Diagn Pathol 40:189–199

Article  PubMed  Google Scholar 

Cancer Genome Atlas Research Network; Linehan WM, Spellman PT, Ricketts CJ, Creighton CJ, Fei SS, Davis C et al (2016) Comprehensive molecular characterization of papillary renal-cell carcinoma. N Engl J Med 374:135–145

Delahunt B, Eble JN (1997) Papillary renal cell carcinoma: a clinicopathologic and immunohistochemical study of 105 tumors. Mod Pathol 10:537–544

CAS  PubMed  Google Scholar 

Cairns P (2010) Renal cell carcinoma. Cancer Biomark 9:461–473

Article  PubMed  Google Scholar 

Amin MB, Amin MB, Tamboli P, Javidan J, Stricker H, de-Peralta Venturina M et al (2002) Prognostic impact of histologic subtyping of adult renal epithelial neoplasms: an experience of 405 cases. Am J Surg Pathol 26:281-91

Comments (0)

No login
gif