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Nonsense-mediated mRNA decay of metal-binding activator MAC1 is dependent on copper levels and 3′-UTR length in Saccharomyces cerevisiae
Nonsense-mediated mRNA decay of metal-binding activator MAC1 is dependent on copper levels and 3′-UTR length in Saccharomyces cerevisiae
The nonsense-mediated mRNA decay (NMD) pathway was initially identified as a surveillance pathway that degrades mRNAs cont...
Hypothesis: evidence that the PRS gene products of Saccharomyces cerevisiae support both PRPP synthesis and maintenance of cell wall integrity
Hypothesis: evidence that the PRS gene products of Saccharomyces cerevisiae support both PRPP synthesis and maintenance of cell wall integrity
The gene products of PRS1-PRS5 in Saccharomyces cerevisiae are responsible for the production of PRPP (5-phospho-D-ribosyl...
Mutational analyses of the interacting domains of Schizosaccharomyces pombe Byr2 with 14-3-3s
Mutational analyses of the interacting domains of Schizosaccharomyces pombe Byr2 with 14-3-3s
The Byr2 kinase of fission yeast Schizosaccharomyces pombe is recruited to the membrane with the assistance of Ras1. Byr2 ...
Use of the Saccharomycopsis schoenii MET17 promoter for regulated heterologous gene expression
Use of the Saccharomycopsis schoenii MET17 promoter for regulated heterologous gene expression
The ability to regulate the expression of genes is a central tool for the characterization of fungal genes. This is of par...
Comparative genome wise analysis of codon usage of Staphylococcus Genus
Comparative genome wise analysis of codon usage of Staphylococcus Genus
The genus Staphylococcus encompasses a diverse array of bacteria with significant implications for human health, including...
Optimizing CaCl2-mediated transformation of Pseudomonas aeruginosa SDK-6 with pJN105 using OFAT: A novel and efficient cloning approach
Optimizing CaCl2-mediated transformation of Pseudomonas aeruginosa SDK-6 with pJN105 using OFAT: A novel and efficient cloning approach
Cloning and expression of a gene in the desired host is required for optimum production in recombinant strains. The presen...
Employment of pqqE gene as molecular marker for the traceability of Gram negative phosphate solubilizing bacteria associated to plants
Employment of pqqE gene as molecular marker for the traceability of Gram negative phosphate solubilizing bacteria associated to plants
Insoluble phosphorous compounds solubilization by soil bacteria is of great relevance since it puts available the phosphor...
Insights into the whole genome sequence of Bacillus thuringiensis NBAIR BtPl, a strain toxic to the melon fruit fly, Zeugodacus cucurbitae
Insights into the whole genome sequence of Bacillus thuringiensis NBAIR BtPl, a strain toxic to the melon fruit fly, Zeugodacus cucurbitae
Bacillus thuringiensis is the most widely used biopesticide, targets a diversity of insect pests belonging to several orde...
GATA family transcription factors in alga Chlamydomonas reinhardtii
GATA family transcription factors in alga Chlamydomonas reinhardtii
GATA family transcription factors (GATA-TFs) are metalloproteins that regulate many metabolic pathways. These conserved pr...
Editorial evolution: welcoming our new editors-in-chief
Editorial evolution: welcoming our new editors-in-chief
Current Genetics has published significant research on how microbes work for nearly h...
Functional insights of three RING-finger peroxins in the life cycle of the insect pathogenic fungus Beauveria bassiana
Functional insights of three RING-finger peroxins in the life cycle of the insect pathogenic fungus Beauveria bassiana
Peroxisomes play important roles in fungal physiological processes. The RING-finger complex consists of peroxins Pex2, Pex...
Expression of human BRCA2 in Saccharomyces cerevisiae complements the loss of RAD52 in double-strand break repair
Expression of human BRCA2 in Saccharomyces cerevisiae complements the loss of RAD52 in double-strand break repair
BRCA2 is a tumor-suppressor gene that is normally expressed in the breast and ovarian tissue of mammals. The BRCA2 protein...
Tips for efficiently maintaining pET expression plasmids
Tips for efficiently maintaining pET expression plasmids
pET expression plasmids are widely used for producing recombinant proteins in Escherichia coli. Selection and maintenance ...
Ino2, activator of yeast phospholipid biosynthetic genes, interacts with basal transcription factors TFIIA and Bdf1
Ino2, activator of yeast phospholipid biosynthetic genes, interacts with basal transcription factors TFIIA and Bdf1
Binding of general transcription factors TFIID and TFIIA to basal promoters is rate-limiting for transcriptional initiatio...
Comparative transcriptome analysis to unveil genes affecting the host cuticle destruction in Metarhizium rileyi
Comparative transcriptome analysis to unveil genes affecting the host cuticle destruction in Metarhizium rileyi
Insect pathogenic fungi, also known as entomopathogenic fungi, are one of the largest insect pathogenic microorganism comm...
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks
Eukaryotic DNA replication is accompanied by the disassembly and reassembly of nucleosomes and the transmission of epigene...
Yeast of Eden: microbial resistance to glyphosate from a yeast perspective
Yeast of Eden: microbial resistance to glyphosate from a yeast perspective
First marketed as RoundUp, glyphosate is history’s most popular herbicide because of its low acute toxicity to metaz...
Insights from metagenome-assembled genomes on the genetic stability and safety of over-the-counter probiotic products
Insights from metagenome-assembled genomes on the genetic stability and safety of over-the-counter probiotic products
The demand for and acceptance of probiotics is determined by their quality and safety. Illumina NGS sequencing and analyti...
Amyloids and prions in the light of evolution
Amyloids and prions in the light of evolution
Functional amyloids have been identified in a wide variety of organisms including bacteria, fungi, plants, and vertebrates...
The antifungal effect induced by itraconazole in Candida parapsilosis largely depends on the oxidative stress generated at the mitochondria
The antifungal effect induced by itraconazole in Candida parapsilosis largely depends on the oxidative stress generated at the mitochondria
In Candida parapsilosis, homozygous disruption of the two genes encoding trehalase activity increased the susceptibility t...
The N-terminal disordered region of ChsB regulates its efficient transport to the hyphal apical surface in Aspergillus nidulans
The N-terminal disordered region of ChsB regulates its efficient transport to the hyphal apical surface in Aspergillus nidulans
In fungi, the cell wall plays a crucial role in morphogenesis and response to stress from the external environment. Chitin...
Tfs1, transcription elongation factor TFIIS, has an impact on chromosome segregation affected by pka1 deletion in Schizosaccharomyces pombe
Tfs1, transcription elongation factor TFIIS, has an impact on chromosome segregation affected by pka1 deletion in Schizosaccharomyces pombe
The cAMP-dependent protein kinase (PKA) pathway in Schizosaccharomyces pombe plays an important role in microtubule organi...
Application of nanotags and nanobodies for live cell single-molecule imaging of the Z-ring in Escherichia coli
Application of nanotags and nanobodies for live cell single-molecule imaging of the Z-ring in Escherichia coli
Understanding where proteins are localized in a bacterial cell is essential for understanding their function and regulatio...
Diverse and dynamic forms of gene regulation by the S. cerevisiae histone methyltransferase Set1
Diverse and dynamic forms of gene regulation by the S. cerevisiae histone methyltransferase Set1
Gene transcription is an essential and highly regulated process. In eukaryotic cells, the structural organization of nucle...
Morphogenic plasticity: the pathogenic attribute of Candida albicans
Morphogenic plasticity: the pathogenic attribute of Candida albicans
Candida albicans is a commensal organism of the human gastrointestinal tract and a prevalent opportunistic pathogen. It ex...