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T2T-YAO, T2T-SHUN, and more
T2T-YAO, T2T-SHUN, and more
Available online 22 September 2023Author links open overlay panel, © 2024 The Authors. Published by Elsevier B.V. and Scie...
T2T-YAO Reference Genome of Han Chinese — New Step in Advancing Precision Medicine in China
T2T-YAO Reference Genome of Han Chinese — New Step in Advancing Precision Medicine in China
Available online 22 September 2023Author links open overlay panel© 2024 The Authors. Published by Elsevier B.V. and Scienc...
A Review of Machine Learning and Algorithmic Methods for Protein Phosphorylation Site Prediction
A Review of Machine Learning and Algorithmic Methods for Protein Phosphorylation Site Prediction
PhosphorylationMachine learningDeep learningPost-translational modificationDatabase© 2022 The Authors. Published by Elsevi...
Toward A New Paradigm of Genomics Research: —Celebration of the 20th Anniversary of Beijing Institute of Genomics.
Toward A New Paradigm of Genomics Research: —Celebration of the 20th Anniversary of Beijing Institute of Genomics.
Available online 29 October 2023Author links open overlay panel, , AbstractTwenty years after the completion and forty yea...
Ribonucleic Acid Modification and Epitranscriptomics
Ribonucleic Acid Modification and Epitranscriptomics
Available online 19 October 2023Author links open overlay panel, © 2023 The Authors. Published by Elsevier B.V. and Scienc...
RCoV19: A One-stop Hub for SARS-CoV-2 Genome Data Integration, Variant Monitoring, and Risk Pre-warning
RCoV19: A One-stop Hub for SARS-CoV-2 Genome Data Integration, Variant Monitoring, and Risk Pre-warning
Available online 26 October 2023Author links open overlay panel, , , , , , , , , , , AbstractThe Resource for Coronavirus ...
Toward A New Paradigm of Genomics Research
Toward A New Paradigm of Genomics Research
Available online 29 October 2023Author links open overlay panel, , AbstractTwenty years after the completion and forty yea...
A Historic Retrospective on the Early Bioinformatics Research in China
A Historic Retrospective on the Early Bioinformatics Research in China
Available online 3 November 2023Author links open overlay panel© 2023 The Authors. Published by Elsevier B.V. and Science ...
Toward Inclusiveness and Thoroughness: A Paradigm Shift from More-ever-omics to Holovivology
Toward Inclusiveness and Thoroughness: A Paradigm Shift from More-ever-omics to Holovivology
Available online 24 October 2023Author links open overlay panel© 2023 The Authors. Published by Elsevier B.V. and Science ...
RNA Modification and Epitranscriptomics
RNA Modification and Epitranscriptomics
Available online 19 October 2023Author links open overlay panelChengqi Yi 1 2 3, Jianhua Yang 4 5Show moreRecommended arti...
A Review of Machine Learning and Algorithmic Methods for Protein Phosphorylation Sites Prediction
A Review of Machine Learning and Algorithmic Methods for Protein Phosphorylation Sites Prediction
Post-translational modifications (PTMs) have key roles in extending the functional diversity of proteins and as a result, ...
From BIG Data Center to China National Center for Bioinformation
From BIG Data Center to China National Center for Bioinformation
Available online 12 October 2023Author links open overlay panel, © 2023 The Authors. Published by Elsevier B.V. and Scienc...
OBIA: An Open Biomedical Imaging Archive
OBIA: An Open Biomedical Imaging Archive
With the development of artificial intelligence (AI) technologies, biomedical imaging data play an important role in scien...
T2T-YAO, T2T-SHUN, and more
T2T-YAO, T2T-SHUN, and more
Available online 22 September 2023Author links open overlay panel, © 2023 The Authors. Published by Elsevier B.V. and Scie...
T2T-YAO Reference Genome of Han Chinese — New Step in Advancing Precision Medicine in China
T2T-YAO Reference Genome of Han Chinese — New Step in Advancing Precision Medicine in China
Available online 22 September 2023Author links open overlay panel© 2023 The Authors. Published by Elsevier B.V. and Scienc...
Non-small Cell Lung Cancer Epigenomes Exhibit Altered DNA Methylation in Smokers and Never-smokers
Non-small Cell Lung Cancer Epigenomes Exhibit Altered DNA Methylation in Smokers and Never-smokers
KeywordsNon-small cell lung cancerEpigenomicsM&MmethylCRFDNA methylation© 2023 The Authors. Published by Elsevier B.V....
Decoding Human Biology and Disease Using Single-cell Omics Technologies
Decoding Human Biology and Disease Using Single-cell Omics Technologies
Available online 20 September 2023Author links open overlay panel, , AbstractOver the past decade, advances in single-cell...
HPC-Atlas: Computationally Constructing A Comprehensive Atlas of Human Protein Complexes
HPC-Atlas: Computationally Constructing A Comprehensive Atlas of Human Protein Complexes
KeywordsHuman protein complexProtein interaction networkSARS-CoV-2 affected complexMultifunctional proteinComplex identifi...
The First Crested Duck Genome Reveals Clues to Genetic Compensation and Crest Cushion Formation
The First Crested Duck Genome Reveals Clues to Genetic Compensation and Crest Cushion Formation
KeywordsGenetic compensationGenome assemblyChinese crested duckCrest cushionGenome adaptive evolutionData availabilityThe ...
Comprehensive Characterization and Global Transcriptome Analyses of Human Fetal Liver Terminal Erythropoiesis
Comprehensive Characterization and Global Transcriptome Analyses of Human Fetal Liver Terminal Erythropoiesis
KeywordsHuman fetal liverTerminal erythropoiesisTranscriptomeImmortalized erythroid cell lineEnucleationData availabilityT...
NetGO 3.0: A Protein Language Model Improves Large-scale Functional Annotations
NetGO 3.0: A Protein Language Model Improves Large-scale Functional Annotations
Protein function predictionWeb serviceProtein language modelLearning to rankLarge-scale multi-label learning© 2023 The Aut...
T2T-YAO: A Telomere-to-telomere Assembled Diploid Reference Genome for Han Chinese
T2T-YAO: A Telomere-to-telomere Assembled Diploid Reference Genome for Han Chinese
KeywordsReference genomeTelomere-to-telomere assemblyHan ChineseHaplotype-resolved assemblyDiploidData availabilityThe raw...
Differential Transcriptomic Landscapes of SARS-CoV-2 Variants in Multiple Organs from Infected Rhesus Macaques
Raw RNA-seq data have been deposited in the Genome Sequence Archive [86] at National Genomics Data Center, Beijing Institu...
inMTSCCA: An Integrated Multi-task Sparse Canonical Correlation Analysis for Multi-omic Brain Imaging Genetics
Brain imaging geneticsMulti-omic endophenotypeCross-endophenotype associationGenetic risk factorMedical image analysis© 20...
AB-Gen: Antibody Library Design with Generative Pre-trained Transformer and Deep Reinforcement Learning
Protein designTransformerReinforcement learningGenerative modelingMulti-objective optimization© 2023 Published by Elsevier...
Revolutionizing Antibody Discovery: An Innovative AI Model for Generating Robust Libraries
Available online 22 June 2023Author links open overlay panel, © 2023 Published by Elsevier B.V. and Science Press on behal...
Morphine Re-arranges Chromatin Spatial Architecture of Primate Cortical Neurons
KeywordsMorphineRhesus monkeyChromatin spatial architectureTopologically associated domainLoopData availabilityThe raw seq...
Recent Advances in Assembly of Plant Complex Genomes
Plant complex genomeAssembly algorithmsTelomere-to-telomere genomeHaplotype-resolved assemblySequencing technology© 2023 T...
Gut Microbiome Variation Along A Lifestyle Gradient Reveals Threats Faced by Asian Elephants
The data supporting the results of this study can be found in the manuscript and its supplementary information files. Raw ...
Novel Time-dependent Multi-omics Integration in Sepsis-associated Liver Dysfunction
KeywordsMulti-omicsOmics technologySepsis-associated liver dysfunctionSingle omicsTime-dependent integrationData availabil...