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Thiopurines exert harmful effects on spermatogenesis in Nudt15R138C knock-in mice
Thiopurines exert harmful effects on spermatogenesis in Nudt15R138C knock-in mice
The association between thiopurine use and testicular reproductive functions remains unclear. In this study, we investigat...
Considerations for evaluating antibiotic prophylaxis in cirrhotic patients with upper gastrointestinal bleeding in real-world data
Considerations for evaluating antibiotic prophylaxis in cirrhotic patients with upper gastrointestinal bleeding in real-world data
Gastroenterology Medicine Center, Shonan Kamakura General Hospital, 1370-1, Okamoto, Kamakura, Kanagawa, 247-8533, JapanC...
Genomic profile and clinical features of MSI-H and TMB-high pancreatic cancers: real-world data from C-CAT database
Genomic profile and clinical features of MSI-H and TMB-high pancreatic cancers: real-world data from C-CAT database
Microsatellite instability high (MSI-H) and tumor mutational burden high (TMB-high) pancreatic cancer are rare, and inform...
C-CAT's triumph in gastroenterology: the wisdom of cats is infinitely superior
C-CAT's triumph in gastroenterology: the wisdom of cats is infinitely superior
Department of Hepatology, Osaka Metropolitan University Graduate School of Medicine, 1-4-3, Asahi-machi, Abeno-ku, Osaka, ...
The antiferroptotic effect of indigo on ulcerative colitis
The antiferroptotic effect of indigo on ulcerative colitis
The protective effect of indigo on intestinal epithelial cells remains unclear. Yokote Akihito et al. preliminarily invest...
Reply to “Ferroptosis in the colon epithelial cells as a therapeutic target for ulcerative colitis”
Reply to “Ferroptosis in the colon epithelial cells as a therapeutic target for ulcerative colitis”
Stockwell BR, Friedmann Angeli JP, Bayir H, et al. Ferroptosis: a regulated cell death nexus linking metabolism, redox bio...
Lansoprazole inhibits the development of sessile serrated lesions by inducing G1 arrest via Skp2/p27 signaling pathway
Lansoprazole inhibits the development of sessile serrated lesions by inducing G1 arrest via Skp2/p27 signaling pathway
Although the serrated-neoplasia pathway reportedly accounts for 15–30% of colorectal cancer (CRC), no studies on che...
Reply to ‘C-CAT's triumph in gastroenterology: the wisdom of cats is infinitely superior’
Reply to ‘C-CAT's triumph in gastroenterology: the wisdom of cats is infinitely superior’
We greatly appreciate the Journal of Gastroenterology’s policy of providing an open opportunity to discuss unresolved scie...
The magnetic resonance imaging and age-adjusted matrix metalloproteinase-7 assist the diagnosis of biliary atresia
The magnetic resonance imaging and age-adjusted matrix metalloproteinase-7 assist the diagnosis of biliary atresia
We investigated the utilities of the liver-to-psoas apparent diffusion coefficient ratios (LTPAR) yielded by diffusion-wei...
Three-dimensional chromatin landscapes in hepatocellular carcinoma associated with hepatitis B virus
Three-dimensional chromatin landscapes in hepatocellular carcinoma associated with hepatitis B virus
Three-dimensional (3D) chromatin architecture frequently altered in cancer. However, its changes during the pathogenesis o...
Induction of ferroptosis by photodynamic therapy and enhancement of antitumor effect with ferroptosis inducers
Induction of ferroptosis by photodynamic therapy and enhancement of antitumor effect with ferroptosis inducers
Photodynamic therapy (PDT) is an effective tumor treatment that involves the administration of a photosensitizer to genera...
Marked intestinal trans-differentiation by autoimmune gastritis along with ectopic pancreatic and pulmonary trans-differentiation
Marked intestinal trans-differentiation by autoimmune gastritis along with ectopic pancreatic and pulmonary trans-differentiation
Autoimmune gastritis (AIG) is a prevalent chronic inflammatory disease with oncogenic potential that causes destruction of...
Editorial: Comparisons of COVID-19-related disturbance in diagnosis of esophagogastric cancer between the Netherlands and Japan
Editorial: Comparisons of COVID-19-related disturbance in diagnosis of esophagogastric cancer between the Netherlands and Japan
Rutter MD, Brookes M, Lee TJ, et al. Impact of the COVID-19 pandemic on UK endoscopic activity and cancer detection: A nat...
MGAT5/TMEM163 variant is associated with prognosis in ursodeoxycholic acid-treated patients with primary biliary cholangitis
MGAT5/TMEM163 variant is associated with prognosis in ursodeoxycholic acid-treated patients with primary biliary cholangitis
Primary biliary cholangitis (PBC) is a chronic immune-mediated liver disease. Previous genome-wide meta-analysis has ident...
A survey questionnaire evaluating physical activity patterns and determinants in patients with chronic liver disease
A survey questionnaire evaluating physical activity patterns and determinants in patients with chronic liver disease
Physical activity can reduce the risk of morbidity and mortality in patients with chronic liver disease (CLD), whereas phy...
Real-world efficacy and safety of advanced therapies in hospitalized patients with ulcerative colitis
Real-world efficacy and safety of advanced therapies in hospitalized patients with ulcerative colitis
This multicenter observational cohort study aimed to evaluate the utilization and short-term efficacy of advanced therapy ...
Clinical outcome after cessation of nucleos(t)ide analog treatment in chronic hepatitis B patients who achieved HBsAg seroclearance
Clinical outcome after cessation of nucleos(t)ide analog treatment in chronic hepatitis B patients who achieved HBsAg seroclearance
We determined the long-term clinical outcome and the durability of treatment cessation after HBsAg seroclearance following...
Correction: Evidence-based clinical practice guidelines for irritable bowel syndrome 2020
Correction: Evidence-based clinical practice guidelines for irritable bowel syndrome 2020
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which...
Current status and issues in genomic analysis using EUS-FNA/FNB specimens in hepatobiliary–pancreatic cancers
Current status and issues in genomic analysis using EUS-FNA/FNB specimens in hepatobiliary–pancreatic cancers
Comprehensive genomic profiling based on next-generation sequencing has recently been used to provide precision medicine f...