SCI Abstract

search
+
Children’s hepatoblastoma: gender and infant age demand focus in the global burden of disease study 2021
Children’s hepatoblastoma: gender and infant age demand focus in the global burden of disease study 2021
Feng J, Polychronidis G, Heger U, Frongia G, Mehrabi A, Hoffmann K. Incidence trends and survival prediction of hepatoblas...
USP13 promotes hepatic stellate cells activation and aggravates liver fibrosis through deubiquitinating SMAD3
USP13 promotes hepatic stellate cells activation and aggravates liver fibrosis through deubiquitinating SMAD3
Activation of hepatic stellate cells (HSCs) is key to the development of liver fibrosis. Recent studies have highlighted t...
Novel and simplified model for the precise identification of concurrent bacterial infections in patients aged 60 years and older with acute-on-chronic liver diseases: a nationwide, multicentre, prospective cohort study
Novel and simplified model for the precise identification of concurrent bacterial infections in patients aged 60 years and older with acute-on-chronic liver diseases: a nationwide, multicentre, prospective cohort study
We aimed to develop an effective model to identify the risk of concurrent bacterial infections in older patients with acut...
Stage-specific impact of portal hypertension on outcomes after liver resection in hepatocellular carcinoma
Stage-specific impact of portal hypertension on outcomes after liver resection in hepatocellular carcinoma
The impact of clinically significant portal hypertension (CSPH) on patients with hepatocellular carcinoma (HCC) after live...
Hepatic arterial infusion chemotherapy combined with lenvatinib and programmed death receptor-1 inhibitors for hepatocellular carcinoma with Vp4 portal vein tumor thrombus: a multicenter, propensity score matching comparative study
Hepatic arterial infusion chemotherapy combined with lenvatinib and programmed death receptor-1 inhibitors for hepatocellular carcinoma with Vp4 portal vein tumor thrombus: a multicenter, propensity score matching comparative study
Advanced hepatocellular carcinoma (HCC) patients with main/bilobar portal vein tumor thrombus (Vp4) have poor survival and...
Efficacy and safety of targeted therapy and immune checkpoint inhibitors in patients with advanced or metastatic biliary tract cancer: a meta-analysis of and sequential analysis of trials
Efficacy and safety of targeted therapy and immune checkpoint inhibitors in patients with advanced or metastatic biliary tract cancer: a meta-analysis of and sequential analysis of trials
This study aimed to comprehensively evaluate the efficacy and safety of targeted therapy and immune checkpoint inhibitors ...
Metabolic dysfunction-associated steatotic liver disease increases the incidence of metachronous liver metastases from TNM stage 0–II colorectal cancer
Metabolic dysfunction-associated steatotic liver disease increases the incidence of metachronous liver metastases from TNM stage 0–II colorectal cancer
Metachronous colorectal liver metastases (CRLM) had been the main cause of death in most colorectal cancer (CRC) patients ...
Identification of PANoptosis-relevant subgroups and predicting signature to evaluate the prognosis and immune landscape of patients with biliary tract cancer
Identification of PANoptosis-relevant subgroups and predicting signature to evaluate the prognosis and immune landscape of patients with biliary tract cancer
This study conducted molecular subtyping of biliary tract cancer patients based on 19 PANoptosis-related gene signatures. ...
Management and treatment of severe immune-related hepatotoxicity based on clinical and pathological characteristics
Management and treatment of severe immune-related hepatotoxicity based on clinical and pathological characteristics
The management of severe immune-related hepatotoxicity (irH) needs to be further optimized. This study aims to analyze the...
APASL clinical practice guidelines on systemic therapy for hepatocellular carcinoma-2024
APASL clinical practice guidelines on systemic therapy for hepatocellular carcinoma-2024
In Asia–Pacific region, hepatocellular carcinoma is a serious health threat attributing to over 600,000 deaths each ...
The effect of transition timing of regorafenib on treatment outcomes in unresectable hepatocellular carcinoma: a real-world study
The effect of transition timing of regorafenib on treatment outcomes in unresectable hepatocellular carcinoma: a real-world study
Regorafenib is the recommended second-line therapy for unresectable hepatocellular carcinoma (uHCC). Our study aimed to as...
Effects of dapagliflozin on liver steatosis in patients with nonalcoholic fatty liver disease: a randomized controlled trial
Effects of dapagliflozin on liver steatosis in patients with nonalcoholic fatty liver disease: a randomized controlled trial
Nonalcoholic fatty liver disease (NAFLD) is a common liver comorbidity with considerable global consequences. This study e...
Functional B cell deficiency promotes intrahepatic HBV replication and impairs the development of anti-HBV T cell responses
Functional B cell deficiency promotes intrahepatic HBV replication and impairs the development of anti-HBV T cell responses
The pivotal role of antibody-producing B cells in controlling hepatitis B virus (HBV) infection is well-established. Howev...
Low-risk individuals with primary biliary cholangitis and significant liver stiffness: prognosis and treatment
Low-risk individuals with primary biliary cholangitis and significant liver stiffness: prognosis and treatment
Some patients treated with ursodeoxycholic acid (UDCA) or combined fenofibrate had well-controlled biochemical parameters ...
MAFLD but not MASLD increases risk of all-cause mortality in regional Australia, with components of metabolic syndrome exacerbating factors: 20 year longitudinal, cohort study
MAFLD but not MASLD increases risk of all-cause mortality in regional Australia, with components of metabolic syndrome exacerbating factors: 20 year longitudinal, cohort study
Controversy remains whether the mortality risk in people with fatty liver disease (FLD) including metabolic-(dysfunction) ...
Targeted APT8(16–34) obtained by cell-SELEX and its internalization with miR-23-5p into activated hepatic stellate cells
Targeted APT8(16–34) obtained by cell-SELEX and its internalization with miR-23-5p into activated hepatic stellate cells
The activation of hepatic stellate cells play a pivotal role in the pathogenesis of hepatic fibrosis. However, the current...
Global, regional, and national temporal trends in incidence and mortality for liver cancer due to hepatitis B, 1990–2021: a decomposition and age-period-cohort analysis for the Global Burden of Disease Study 2021
Global, regional, and national temporal trends in incidence and mortality for liver cancer due to hepatitis B, 1990–2021: a decomposition and age-period-cohort analysis for the Global Burden of Disease Study 2021
This study comprehensively assessed the burden of liver cancer due to hepatitis B (LCHB) from 1990 to 2021, analyzing temp...
Rheumatoid factor levels indicate cryoglobulinemia severity in hepatitis B e antigen-negative hepatitis B virus carriers: a 7-year prospective cohort study
Rheumatoid factor levels indicate cryoglobulinemia severity in hepatitis B e antigen-negative hepatitis B virus carriers: a 7-year prospective cohort study
The phenotype of cryoglobulinemia in hepatitis B virus (HBV) carriers remains elusive. A 7-year prospective cohort of 648 ...
Predictive model for HBsAg clearance rate in chronic hepatitis B patients treated with pegylated interferon α-2b for 48 weeks
Predictive model for HBsAg clearance rate in chronic hepatitis B patients treated with pegylated interferon α-2b for 48 weeks
Chronic hepatitis B (CHB) is a major global health concern. This study aims to investigate the factors influencing hepatit...
Cell-free DNA methylation-based inflammation score as a marker for hepatocellular carcinoma among people living with HIV
Cell-free DNA methylation-based inflammation score as a marker for hepatocellular carcinoma among people living with HIV
People living with the human immunodeficiency virus (HIV) are at a greater risk of developing hepatocellular carcinoma (HC...
Nomograms should be noted
Nomograms should be noted
Omata M, Cheng AL, Kokudo N, Kudo M, Lee JM, Jia J, et al. Asia-Pacific clinical practice guidelines on the management of ...
Artificial intelligence in liver imaging: methods and applications
Artificial intelligence in liver imaging: methods and applications
Liver disease is regarded as one of the major health threats to humans. Radiographic assessments hold promise in terms of ...
Prevalence and impact on the outcome of myosteatosis in patients with cirrhosis: a systematic review and meta-analysis
Prevalence and impact on the outcome of myosteatosis in patients with cirrhosis: a systematic review and meta-analysis
Myosteatosis in cirrhotic patients has been evaluated in limited studies with conflicting results and no systematic review...
An algorithm for simplified hepatitis C virus treatment with non-specialist care based on nation-wide data from Taiwan
An algorithm for simplified hepatitis C virus treatment with non-specialist care based on nation-wide data from Taiwan
Both European Association for the Study of the Liver (EASL) and American Association for the Study of Liver Diseases and t...
Dairy products intake and prevalence, incidence, and recovery of non-alcoholic fatty liver disease in Chinese population
Dairy products intake and prevalence, incidence, and recovery of non-alcoholic fatty liver disease in Chinese population
Non-alcoholic fatty liver disease (NAFLD) is a growing public health concern. Modifiable factors such as diet and lifestyl...
Liver fibrosis showed a two-phase regression rate during long-term anti-HBV therapy by three-time biopsies assessments
Liver fibrosis showed a two-phase regression rate during long-term anti-HBV therapy by three-time biopsies assessments
Evidence has proven that liver fibrosis or even cirrhosis can be reversed by anti-HBV treatment. However, the difference o...
APASL clinical practice guidelines on the management of acute kidney injury in acute-on-chronic liver failure
APASL clinical practice guidelines on the management of acute kidney injury in acute-on-chronic liver failure
Acute-on-chronic liver failure (ACLF) is a syndrome that is characterized by the rapid development of organ failures predi...
MAFLD as part of systemic metabolic dysregulation
MAFLD as part of systemic metabolic dysregulation
Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases worldwide. In recent years, a ne...
Efficacy and safety of precision-guided transjugular extrahepatic portosystemic shunt (TEPS) in the management of cavernous transformation of the portal vein with portal hypertension: a case series
Efficacy and safety of precision-guided transjugular extrahepatic portosystemic shunt (TEPS) in the management of cavernous transformation of the portal vein with portal hypertension: a case series
Performing a Transjugular intrahepatic portal system shunt (TIPS) in patients with portal vein cavernous transformation (C...
PIVKA-II combined with alpha-fetoprotein for the diagnostic value of hepatic tumors in children: a multicenter, prospective observational study
PIVKA-II combined with alpha-fetoprotein for the diagnostic value of hepatic tumors in children: a multicenter, prospective observational study
To investigate whether protein induced by vitamin K antagonist-II (PIVKA-II) combined with alpha-fetoprotein (AFP) can imp...
Load More
format_indent_increase