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YAP inhibition overcomes adaptive resistance in HER2-positive gastric cancer treated with trastuzumab via the AKT/mTOR and ERK/mTOR axis
YAP inhibition overcomes adaptive resistance in HER2-positive gastric cancer treated with trastuzumab via the AKT/mTOR and ERK/mTOR axis
Human epidermal growth factor receptor 2 (HER2)-positive gastric cancer (GC) is a heterogeneous GC subtype characterized b...
Development of a reliable surgical quality assurance tool for gastrectomy in oncological trials
Development of a reliable surgical quality assurance tool for gastrectomy in oncological trials
Despite its recognized importance, there is currently no reliable tool for surgical quality assurance (SQA) of gastrectomy...
An artificial intelligence system for comprehensive pathologic outcome prediction in early gastric cancer through endoscopic image analysis (with video)
An artificial intelligence system for comprehensive pathologic outcome prediction in early gastric cancer through endoscopic image analysis (with video)
Accurate prediction of pathologic results for early gastric cancer (EGC) based on endoscopic findings is essential in deci...
Global prevalence of claudin 18 isoform 2 in tumors of patients with locally advanced unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma
Global prevalence of claudin 18 isoform 2 in tumors of patients with locally advanced unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma
Limited data exist for global prevalence of claudin 18 isoform 2 (CLDN18.2) positivity and association of CLDN18.2 status ...
Antibody–drug conjugates in gastric cancer: from molecular landscape to clinical strategies
Antibody–drug conjugates in gastric cancer: from molecular landscape to clinical strategies
Antibody–drug conjugates (ADCs) represent a crucial component of targeted therapies in gastric cancer, potentially a...
Gastric microbiome signature for predicting metachronous recurrence after endoscopic resection of gastric neoplasm
Gastric microbiome signature for predicting metachronous recurrence after endoscopic resection of gastric neoplasm
Changes in gastric microbiome are associated with gastric carcinogenesis. Studies on the association between gastric mucos...
A systematic review on the effectiveness of robot-assisted minimally invasive gastrectomy
A systematic review on the effectiveness of robot-assisted minimally invasive gastrectomy
Robot-assisted minimally invasive gastrectomy (RAMIG) is increasingly used as a surgical approach for gastric cancer. This...
Safety and feasibility of single-incision laparoscopic distal gastrectomy in overweight and obese gastric cancer patients: a propensity score-matched analysis
Safety and feasibility of single-incision laparoscopic distal gastrectomy in overweight and obese gastric cancer patients: a propensity score-matched analysis
The technical challenges and safety concerns of single-incision laparoscopic gastrectomy for overweight and obese gastric ...
Genomic events stratifying prognosis of early gastric cancer
Genomic events stratifying prognosis of early gastric cancer
The purpose of the study was to conduct a comprehensive genomic characterization of gene alterations, microsatellite insta...
Importance of duodenal stump reinforcement to prevent stump leakage after gastrectomy: a large-scale multicenter retrospective study (KSCC DELICATE study)
Importance of duodenal stump reinforcement to prevent stump leakage after gastrectomy: a large-scale multicenter retrospective study (KSCC DELICATE study)
The significance of reinforcement of the duodenal stump with seromuscular sutures and the effectiveness of reinforced stap...
Functional genomics reveals an off-target dependency of drug synergy in gastric cancer therapy
Functional genomics reveals an off-target dependency of drug synergy in gastric cancer therapy
Integrating molecular-targeted agents into combination chemotherapy is transformative for enhancing treatment outcomes in ...
Increased cardiovascular disease risk among adolescents and young adults with gastric cancer
Increased cardiovascular disease risk among adolescents and young adults with gastric cancer
Previous studies have investigated cardiovascular disease (CVD) risks in cancer patients, but there is limited knowledge c...
Landscape of homologous recombination deficiency in gastric cancer and clinical implications for first-line chemotherapy
Landscape of homologous recombination deficiency in gastric cancer and clinical implications for first-line chemotherapy
Homologous recombination deficiency (HRD) is one of the crucial hallmarks of cancer. It is associated with a favorable res...
Management challenges and the role of adjuvant chemotherapy in remnant gastric cancer: an analysis of 313 patients from the KEGG multicenter observational study
Management challenges and the role of adjuvant chemotherapy in remnant gastric cancer: an analysis of 313 patients from the KEGG multicenter observational study
Clinical findings and postoperative follow-up data on remnant gastric cancer (RGC) are limited due to its rarity. Addition...
Dietary intake of vitamin C and gastric cancer: a pooled analysis within the Stomach cancer Pooling (StoP) Project
Dietary intake of vitamin C and gastric cancer: a pooled analysis within the Stomach cancer Pooling (StoP) Project
Previous studies suggest that dietary vitamin C is inversely associated with gastric cancer (GC), but most of them did not...
Statin use in relation to long-term survival after gastrectomy for gastric adenocarcinoma: a Swedish population-based cohort study
Statin use in relation to long-term survival after gastrectomy for gastric adenocarcinoma: a Swedish population-based cohort study
Studies have suggested that medication with statins improves survival in patients with gastric cancer, but methodological ...
Diagnostic performance of deep-learning-based virtual chromoendoscopy in gastric neoplasms
Diagnostic performance of deep-learning-based virtual chromoendoscopy in gastric neoplasms
Cycle-consistent generative adversarial network (CycleGAN) is a deep neural network model that performs image-to-image tra...
Biological and targeting differences between the rare KRAS A146T and canonical KRAS mutants in gastric cancer models
Biological and targeting differences between the rare KRAS A146T and canonical KRAS mutants in gastric cancer models
Gastric cancer (GC) is the third leading cause of cancer-related death worldwide, with a poor prognosis for patients with ...
Patient metabolic profile defined by liver and muscle 18F-FDG PET avidity is independently associated with overall survival in gastric cancer
Patient metabolic profile defined by liver and muscle 18F-FDG PET avidity is independently associated with overall survival in gastric cancer
PET–CT-based patient metabolic profiling is a novel concept to incorporate patient-specific metabolism into gastric ...
Correction: Ubiquitous mitochondrial creatine kinase promotes the progression of gastric cancer through a JNK-MAPK/JUN/HK2 axis regulated glycolysis
Correction: Ubiquitous mitochondrial creatine kinase promotes the progression of gastric cancer through a JNK-MAPK/JUN/HK2 axis regulated glycolysis
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Impact of preoperative prealbumin levels on long-term prognosis in patients with gastric cancer after gastrectomy: a retrospective cohort study
Impact of preoperative prealbumin levels on long-term prognosis in patients with gastric cancer after gastrectomy: a retrospective cohort study
The relationship between preoperative prealbumin levels and long-term prognoses in patients with gastric cancer after gast...
Long-term oncological outcomes of 3D versus 2D laparoscopic gastrectomy for gastric cancer: a randomized clinical trial
Long-term oncological outcomes of 3D versus 2D laparoscopic gastrectomy for gastric cancer: a randomized clinical trial
Laparoscopy-assisted gastrectomy (LG) is rapidly gaining popularity owing to its minimal invasiveness. Previous studies ha...
Discrepant effect of high-density lipoprotein cholesterol on esophageal and gastric cancer risk in a nationwide cohort
Discrepant effect of high-density lipoprotein cholesterol on esophageal and gastric cancer risk in a nationwide cohort
The relationship between high-density lipoprotein cholesterol (HDL-C) and gastroesophageal cancer is not constant. In this...
Superior lymph node harvest by fluorescent lymphography during minimally invasive gastrectomy for gastric cancer patients with high body mass index
Superior lymph node harvest by fluorescent lymphography during minimally invasive gastrectomy for gastric cancer patients with high body mass index
Fluorescent lymphography (FL) using indocyanine green (ICG) allows for the visualization of all draining lymph nodes (LNs)...
Adjuvant treatment for locally advanced gastric cancer: an Asian perspective
Adjuvant treatment for locally advanced gastric cancer: an Asian perspective
Standard adjuvant treatment for locally advanced gastric cancer (LAGC) is regionally different. Whereas perioperative chem...
Correction: Resistance to FGFR1-targeted therapy leads to autophagy via TAK1/AMPK activation in gastric cancer
Correction: Resistance to FGFR1-targeted therapy leads to autophagy via TAK1/AMPK activation in gastric cancer
Department of General Surgery, Research Center for Clinical Oncology, The Affiliated Cancer Hospital of Nanjing Medical Un...
Perioperative chemotherapy with docetaxel plus oxaliplatin and S-1 (DOS) versus oxaliplatin plus S-1 (SOX) for the treatment of locally advanced gastric or gastro-esophageal junction adenocarcinoma (MATCH): an open-label, randomized, phase 2 clinical trial
Perioperative chemotherapy with docetaxel plus oxaliplatin and S-1 (DOS) versus oxaliplatin plus S-1 (SOX) for the treatment of locally advanced gastric or gastro-esophageal junction adenocarcinoma (MATCH): an open-label, randomized, phase 2 clinical trial
It remains unclear whether addition of docetaxel to the combination of a platinum and fluoropyrimidine could provide more ...
Bemarituzumab as first-line treatment for locally advanced or metastatic gastric/gastroesophageal junction adenocarcinoma: final analysis of the randomized phase 2 FIGHT trial
Bemarituzumab as first-line treatment for locally advanced or metastatic gastric/gastroesophageal junction adenocarcinoma: final analysis of the randomized phase 2 FIGHT trial
We report the final results of the randomized phase 2 FIGHT trial that evaluated bemarituzumab, a humanized monoclonal ant...
Elucidating molecular mechanisms and therapeutic synergy: irreversible HER2-TKI plus T-Dxd for enhanced anti-HER2 treatment of gastric cancer
Elucidating molecular mechanisms and therapeutic synergy: irreversible HER2-TKI plus T-Dxd for enhanced anti-HER2 treatment of gastric cancer
HER2-targeted therapies have improved the outcomes of HER2-positive gastric cancer (GC), yet resistance remains a challeng...
Gastric fundic gland polyposis and cancer development after eradication of Helicobacter pylori in patient with gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS)
Gastric fundic gland polyposis and cancer development after eradication of Helicobacter pylori in patient with gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS)
A 44-year-old woman with gastric cancer (GC) and fundic gland polyposis (FGPs) was referred to our hospital for further di...
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