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Guidelines for Neuroprognostication in Critically Ill Adults with Moderate–Severe Traumatic Brain Injury
Guidelines for Neuroprognostication in Critically Ill Adults with Moderate–Severe Traumatic Brain Injury
Moderate–severe traumatic brain injury (msTBI) carries high morbidity and mortality worldwide. Accurate neuroprognos...
Clinical Outcome Prediction of Early Brain Injury in Aneurysmal Subarachnoid Hemorrhage: the SHELTER-Score
Clinical Outcome Prediction of Early Brain Injury in Aneurysmal Subarachnoid Hemorrhage: the SHELTER-Score
Despite intensive research on preventing and treating vasospasm and delayed cerebral ischemia in aneurysmal subarachnoid h...
Inflammation as a Source of Cardiac Injury After Subarachnoid Hemorrhage
Inflammation as a Source of Cardiac Injury After Subarachnoid Hemorrhage
Cardiac injury commonly occurs in patients after a cerebrovascular event, but it is n...
Multiorgan Dysfunction Syndrome in Abusive and Accidental Pediatric Traumatic Brain Injury
Multiorgan Dysfunction Syndrome in Abusive and Accidental Pediatric Traumatic Brain Injury
Abusive head trauma (AHT) is a mechanism of pediatric traumatic brain injury (TBI) with high morbidity and mortality. Mult...
Clinical Outcomes and Systemic Complications Related to the Severity and Etiology of Status Epilepticus Using a Common Data Model
Clinical Outcomes and Systemic Complications Related to the Severity and Etiology of Status Epilepticus Using a Common Data Model
Status epilepticus (SE) is a critical neurological emergency in patients with neurological and nonneurological diseases. M...
Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group in the Pediatric Population
Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group in the Pediatric Population
The fundamental gap obstructing forward progress of evidenced-based care in pediatric and neonatal disorders of consciousn...
Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Physiology and Big Data
Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Physiology and Big Data
The Curing Coma Campaign Collaborators are listed in the Supplementary Appendix. The Curing Coma Campaign and its Contribu...
A Proposal for a New Protocol for Sonographic Assessment of the Optic Nerve Sheath Diameter: The CLOSED Protocol
A Proposal for a New Protocol for Sonographic Assessment of the Optic Nerve Sheath Diameter: The CLOSED Protocol
Aspide R, Bertolini G, Albini Riccioli L, Mazzatenta D, Palandri G, Biasucci DG. A proposal for a new protocol for sonogra...
The State of the Field of Pediatric Multimodality Neuromonitoring
The State of the Field of Pediatric Multimodality Neuromonitoring
The use of multimodal neuromonitoring in pediatrics is in its infancy relative to adult neurocritical care. Multimodal neu...
Overlapping Physiologic Signs of Sepsis and Paroxysmal Sympathetic Hyperactivity After Traumatic Brain Injury: Exploring A Clinical Conundrum
Overlapping Physiologic Signs of Sepsis and Paroxysmal Sympathetic Hyperactivity After Traumatic Brain Injury: Exploring A Clinical Conundrum
Paroxysmal sympathetic hyperactivity (PSH) occurs in a subset of patients with traumatic brain injury (TBI) and is associa...
Clinical Trial Protocol for BEACH: A Phase 2a Study of MW189 in Patients with Acute Nontraumatic Intracerebral Hemorrhage
Clinical Trial Protocol for BEACH: A Phase 2a Study of MW189 in Patients with Acute Nontraumatic Intracerebral Hemorrhage
Patients with acute spontaneous intracerebral hemorrhage (ICH) develop secondary neuroinflammation and cerebral edema that...
Burst Suppression as a Treatment Goal in Refractory Status Epilepticus
Burst Suppression as a Treatment Goal in Refractory Status Epilepticus
The use of burst suppression has long been considered a therapeutic goal in the manag...
Guidelines for Neuroprognostication in Critically Ill Adults with Intracerebral Hemorrhage
Guidelines for Neuroprognostication in Critically Ill Adults with Intracerebral Hemorrhage
The objective of this document is to provide recommendations on the formal reliability of major clinical predictors often ...
Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Behavioral Phenotyping
Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Behavioral Phenotyping
Department of Neurology, Tufts University School of Medicine, Boston, MA, USAAleksandra YakhkindDepartment of Medicine (Cr...
The Origin of the Burst-Suppression Paradigm in Treatment of Status Epilepticus
The Origin of the Burst-Suppression Paradigm in Treatment of Status Epilepticus
After electroencephalography (EEG) was introduced in hospitals, early literature recognized burst-suppression pattern (BSP...
Improved Transcranial Doppler Waveform Analysis for Intracranial Hypertension Assessment in Patients with Traumatic Brain Injury
Improved Transcranial Doppler Waveform Analysis for Intracranial Hypertension Assessment in Patients with Traumatic Brain Injury
Transcranial Doppler (TCD) is a noninvasive bedside tool for cerebral hemodynamic assessments in multiple clinical scenari...
Intracranial Hypertension with Patent Basal Cisterns: Controlled Lumbar Drainage as a Therapeutic Option. Selected Case Series
Intracranial Hypertension with Patent Basal Cisterns: Controlled Lumbar Drainage as a Therapeutic Option. Selected Case Series
There are pathological conditions in which intracranial hypertension and patent basal cisterns in computed tomography coex...
Novel EEG Metric Correlates with Intracranial Pressure in an Animal Model
Novel EEG Metric Correlates with Intracranial Pressure in an Animal Model
Intracranial pressure (ICP) can be continuously and reliably measured using invasive monitoring through an external ventri...
Postictal Encephalopathy After Status Epilepticus: Outcome and Risk Factors
Postictal Encephalopathy After Status Epilepticus: Outcome and Risk Factors
Postictal encephalopathy is well known after status epilepticus (SE), but its prognostic impact and triggers are unknown. ...
Guidelines for neuroprognostication in adults with traumatic spinal cord injury
Guidelines for neuroprognostication in adults with traumatic spinal cord injury
Traumatic spinal cord injury (tSCI) impacts patients and their families acutely and often for the long term. The ability o...
Suboptimal Cerebral Perfusion is Associated with Ischemia After Intracerebral Hemorrhage
Suboptimal Cerebral Perfusion is Associated with Ischemia After Intracerebral Hemorrhage
Remote ischemic lesions on diffusion-weighted imaging (DWI) occur in one third of patients with intracerebral hemorrhage (...
Association Between Monocyte-to-Lymphocyte Ratio and Hematoma Progression After Cerebral Contusion
Association Between Monocyte-to-Lymphocyte Ratio and Hematoma Progression After Cerebral Contusion
The objective of this research was to examine the impact of the monocyte-to-lymphocyte ratio (MLR) on the advancement of h...