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Ubrogepant alleviates migraine premonitory symptoms
A new phase III trial has shown that the small-molecule CGRP receptor antagonist ubrogepant can alleviate premonitory symp...
Author Correction: A neuroscientific model of near-death experiences
These authors contributed equally: Charlotte Martial, Pauline Fritz.Coma Science Group, GIGA-Consciousness, GIGA Institute...
α-Synuclein pathology in LRRK2 Parkinson disease
Absence of Lewy body pathology in the form of Parkinson disease caused by mutations in the LRRK2 gene does not equate to a...
Epigenetic clocks and DNA methylation biomarkers of brain health and disease
Epigenetic clocks and DNA methylation biomarkers of brain health and disease
Ageing has profound effects on the human brain across the lifespan. Cognitive testing and brain imaging are currently used...
Influence of sleep and chronotypes: are we adapted to today’s society?
Aspects of modern society, such as artificial lighting and rigid schedules, create ‘social jetlag’ — a m...
AI, neurotechnology and society — a question of trust
Artificial intelligence and neurotechnology promise to transform neurological care, but their acceptance will depend on pu...
Neurological complications of CAR T cell therapy for cancers
Neurological complications of CAR T cell therapy for cancers
Genetically engineered chimeric antigen receptor (CAR) T cells have emerged as a powerful treatment option in patients wit...
Brain–computer interface restores naturalistic speech to a man with ALS
Brain–computer interface restores naturalistic speech to a man with ALS
A voice-synthesis neuroprosthesis based on a brain–computer interface has restored instantaneous, natural-sounding s...
Glymphatic dysfunction in PD clinical progression
Risk of clinical milestones in Parkinson disease (PD) is associated with reduced glymphatic drainage, according to new res...
Dementia risk scores in diverse populations
A recent analysis of dementia risk scores across diverse populations found that the validity of scores can differ between ...
High prevalence of hepatitis B in NMOSD
A new study of a Taiwanese cohort found a high prevalence of resolved hepatitis B virus (HBV) infection in people with neu...
Immune responses influence sex differences in Alzheimer disease
Sex differences in Alzheimer disease could be influenced by differences in immune responses, new research suggests.
Intracerebral haemorrhage — mechanisms, diagnosis and prospects for treatment and prevention
Intracerebral haemorrhage — mechanisms, diagnosis and prospects for treatment and prevention
Intracerebral haemorrhage (ICH) is a devastating condition associated with high mortality and substantial residual disabil...
Diets to promote healthy brain ageing
Diets to promote healthy brain ageing
Diet is a modifiable lifestyle factor with a proven role in cardiovascular disease risk reduction that might also play an ...
Moving beyond immunoglobulin therapy for CIDP with efgartigimod
The FDA recently approved efgartigimod for the treatment of chronic inflammatory demyelinating polyradiculopathy, providin...
α-Synuclein pathology as a target in neurodegenerative diseases
α-Synuclein pathology as a target in neurodegenerative diseases
α-Synuclein misfolds into pathological forms that lead to various neurodegenerative diseases known collectively as &#...
Towards the era of biological biomarkers for Parkinson disease
Since its instigation in cancer research in the 1930s, the disease-staging concept has become a crucial tool in clinical r...
Neurological care for LGBT+ people
Neurological care for LGBT+ people
Sexual and gender minority (LGBT+) people face unique health disparities that must be considered by health-care providers ...
Approval of omaveloxolone for Friedreich ataxia
The recent approval of omaveloxolone for the treatment of Friedreich ataxia in the USA and Europe represents an important ...
Neurostimulation for treatment of post-stroke impairments
Neurostimulation for treatment of post-stroke impairments
Neurostimulation, the use of electrical stimulation to modulate the activity of the nervous system, is now commonly used f...
Insights into epileptogenesis from post-traumatic epilepsy
Insights into epileptogenesis from post-traumatic epilepsy
Post-traumatic epilepsy (PTE) accounts for 5% of all epilepsies. The incidence of PTE after traumatic brain injury (TBI) d...
Diversity, equity and inclusion in neurology
In this issue of Nature Reviews Neurology, we launch a Series to highlight the importance of diversity, equity and inclusi...
Addressing disparities in neurology by building the workforce in LMICs
Addressing disparities in neurology by building the workforce in LMICs
Nature Reviews Neurology is interviewing individuals who are driving efforts to address disparities in neurology through a...
Support for network theories of schizophrenia
Support for network theories of schizophrenia
A computational neuroimaging study has shed new light on the relationship between morphological changes in the brain in sc...
Improved quality of life with MS treatment
Cladribine tablets can improve quality of life in people with highly active relapsing multiple sclerosis (MS), according t...
IGFBP2 levels associated with Alzheimer disease
A study published in Brain has found correlations between serum and cerebrospinal fluid levels of insulin-like growth fact...
A multiple hits hypothesis for memory dysfunction in Parkinson disease
A multiple hits hypothesis for memory dysfunction in Parkinson disease
Cognitive disorders are increasingly recognized in Parkinson disease (PD), even in early disease stages, and memory is one...
Restoring synaptic plasticity after stroke
Gamma oscillations induced by optogenetic stimulation restore functional synaptic plasticity in a mouse model of stroke, a...
CD11c+ macrophages mediate brain-to-gut α-synuclein trafficking
CD11c+ macrophages mediate brain-to-gut α-synuclein trafficking
New research indicates that in a mouse model of Parkinson disease, α-synuclein is trafficked from the brain to the gu...
ALS pathogenesis linked to actin barrier collapse
Repulsive guidance molecule A (RGMa) regulates actin dynamics via neogenin 1 signalling. A new study found that the cerebr...
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