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Asymptomatic carotid stenosis is associated with gray and white matter damage
Asymptomatic carotid stenosis is associated with gray and white matter damage
Background Cognitive deficits in patients with asymptomatic carotid stenosis have been reported. The ultimate mechanism of...
Severe cerebral white matter lesions in ischemic stroke patients are associated with less time spent at home and early institutionalization
Severe cerebral white matter lesions in ischemic stroke patients are associated with less time spent at home and early institutionalization
Background Cerebral white matter lesions are one imaging surrogate for cerebral small vessel disease. These white matter l...
Life‐threatening coronary disease is prevalent in patients with stenosing carotid artery disease
Life‐threatening coronary disease is prevalent in patients with stenosing carotid artery disease
Background Atherosclerosis affects several vascular trees systemically and though surgical plaque removal diminishes the r...
Ischemic involvement of the primary motor cortex is a prognostic factor in acute stroke
Ischemic involvement of the primary motor cortex is a prognostic factor in acute stroke
Background The location of the primary motor cortex can be detected in healthy adults using the findings of ‘T2 hyp...
Statistical analysis plan for evaluating low‐ vs. standard‐dose alteplase in the ENhanced Control of Hypertension and Thrombolysis strokE stuDy (ENCHANTED)
Statistical analysis plan for evaluating low‐ vs. standard‐dose alteplase in the ENhanced Control of Hypertension and Thrombolysis strokE stuDy (ENCHANTED)
Background The ENhanced Control of Hypertension And Thrombolysis strokE stuDy trial is a 2 × 2 quasi-fa...
Specialized stroke rehabilitation services in seven countries
Specialized stroke rehabilitation services in seven countries
Background There is a lack of defined levels of rehabilitation, indicating possibly random content and access to specializ...
Posterior vs. anterior circulation infarction: demography, outcomes, and frequency of hemorrhage after thrombolysis
Posterior vs. anterior circulation infarction: demography, outcomes, and frequency of hemorrhage after thrombolysis
Background Intravenous thrombolysis is considered to be the standard specific reperfusion therapy in acute ischemic stroke...
Heavy ethanol consumption aggravates the ischemic cerebral injury by inhibiting ALDH2
Heavy ethanol consumption aggravates the ischemic cerebral injury by inhibiting ALDH2
Background Heavy ethanol consumption is widely accepted as a risk for ischemic stroke. The molecular mechanisms of ethanol...
The efficacy of Wii‐based Movement Therapy for upper limb rehabilitation in the chronic poststroke period: a randomized controlled trial
The efficacy of Wii‐based Movement Therapy for upper limb rehabilitation in the chronic poststroke period: a randomized controlled trial
Background More effective and efficient rehabilitation is urgently needed to address the prevalence of unmet rehabilitatio...
APOE/TOMM40 genetic loci, white matter hyperintensities, and cerebral microbleeds
APOE/TOMM40 genetic loci, white matter hyperintensities, and cerebral microbleeds
Background Two markers of cerebral small vessel disease are white matter hyperintensities and cerebral microbleeds, which ...
Internet‐based information‐seeking behavior for transient ischemic attack
Internet‐based information‐seeking behavior for transient ischemic attack
Background In recent years, Internet became an increasingly important tool for accessing health information and is being u...
Sparing of the hippocampus indicates better collateral blood flow in acute posterior cerebral artery occlusion
Sparing of the hippocampus indicates better collateral blood flow in acute posterior cerebral artery occlusion
Background In acute posterior cerebral artery, occlusion involvement of the hippocampus is a common finding. Nevertheless,...
Novel TIA biomarkers identified by mass spectrometry‐based proteomics
Novel TIA biomarkers identified by mass spectrometry‐based proteomics
Background Transient ischemic attacks remain a clinical diagnosis with significant variability between physicians. Finding...
Heart rate and ischemic stroke: the REasons for Geographic And Racial Differences in Stroke (REGARDS) study
Heart rate and ischemic stroke: the REasons for Geographic And Racial Differences in Stroke (REGARDS) study
Background The association between resting heart rate and ischemic stroke remains unclear. Aim To examine the association ...
High rate of microbleed formation following primary intracerebral hemorrhage
High rate of microbleed formation following primary intracerebral hemorrhage
Background We sought to investigate the frequency of microbleed development following intracerebral hemorrhage in a predom...
The association between lesion location and functional outcome after ischemic stroke
The association between lesion location and functional outcome after ischemic stroke
Background Infarct location has a critical effect on patient outcome after ischemic stroke, but the study of its role inde...
Sirtuin/uncoupling protein gene variants and carotid plaque area and morphology
Sirtuin/uncoupling protein gene variants and carotid plaque area and morphology
Background Sirtuins and uncoupling proteins have been implicated in cardiovascular diseases by controlling oxidative stres...
The Multi‐National survey on Epidemiology, Morbidity, and Outcomes iN Intracerebral Haemorrhage (MNEMONICH)
The Multi‐National survey on Epidemiology, Morbidity, and Outcomes iN Intracerebral Haemorrhage (MNEMONICH)
Intracerebral haemorrhage (ICH) is a devastating condition with no treatment and poorly understood pathophysiology. Due to...
Design of Randomized, double‐blind, Evaluation in secondary Stroke Prevention comparing the EfficaCy and safety of the oral Thrombin inhibitor dabigatran etexilate vs. acetylsalicylic acid in patients with Embolic Stroke of Undetermined Source (RE‐SPECT ESUS)
Design of Randomized, double‐blind, Evaluation in secondary Stroke Prevention comparing the EfficaCy and safety of the oral Thrombin inhibitor dabigatran etexilate vs. acetylsalicylic acid in patients with Embolic Stroke of Undetermined Source (RE‐SPECT ESUS)
Rationale Cryptogenic ischemic strokes constitute 20–30% of ischemic strokes, the majority of which are embolic str...
Celebrating 10 years of the International Journal of Stroke!
Celebrating 10 years of the International Journal of Stroke!
This edition is landmark in several ways. First, it marks the end of our 10th year of publication, in which we have seen t...
Dural arteriovenous fistula presenting as a seizure mimicking transient ischemic attack: advantages of susceptibility‐weighted imaging
Dural arteriovenous fistula presenting as a seizure mimicking transient ischemic attack: advantages of susceptibility‐weighted imaging
A dural arteriovenous fistula (DAVF) can occur anywhere within the intracranial dura mater 1. Its manifestations are nonsp...
Acute Stroke or Transient Ischemic Attack Treated with Aspirin or Ticagrelor and Patient Outcomes (SOCRATES) trial: rationale and design
Acute Stroke or Transient Ischemic Attack Treated with Aspirin or Ticagrelor and Patient Outcomes (SOCRATES) trial: rationale and design
Rationale The risk of recurrent ischemia is high in the acute period after ischemic stroke and transient ischemic attack. ...
Cerebrovascular correlates of vitamin D deficiency in older adults living near the Equator: results from the Atahualpa Project
Cerebrovascular correlates of vitamin D deficiency in older adults living near the Equator: results from the Atahualpa Project
All studies attempting to find an association between vitamin D deficiency and cerebrovascular diseases have been conducte...
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