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Nanocarriers for targeted drug delivery in the vascular system: focus on endothelium
Nanocarriers for targeted drug delivery in the vascular system: focus on endothelium
Endothelial cells (ECs) are pivotal in maintaining vascular health, regulating hemodynamics, and modulating inflammatory r...
Conformal immunomodulatory hydrogels for the treatment of otitis media
Conformal immunomodulatory hydrogels for the treatment of otitis media
Otitis media (OM), a condition stemming from the proliferation of various bacteria within the tympanic cavity (TC), is com...
Smart photonic crystal hydrogels for visual glucose monitoring in diabetic wound healing
Smart photonic crystal hydrogels for visual glucose monitoring in diabetic wound healing
Diabetes is a global chronic disease that seriously endangers human health and characterized by abnormally high blood gluc...
Immunomodulating melatonin-decorated silica nanoparticles suppress bacterial wilt (Ralstonia solanacearum) in tomato (Solanum lycopersicum L.) through fine-tuning of oxidative signaling and rhizosphere bacterial community
Immunomodulating melatonin-decorated silica nanoparticles suppress bacterial wilt (Ralstonia solanacearum) in tomato (Solanum lycopersicum L.) through fine-tuning of oxidative signaling and rhizosphere bacterial community
Tomato (Solanum lycopersicum L.) production is severely threatened by bacterial wilt, caused by the phytopathogenic bacter...
Chemical screens for particle-induced macrophage death identifies kinase inhibitors of phagocytosis as targets for toxicity
Chemical screens for particle-induced macrophage death identifies kinase inhibitors of phagocytosis as targets for toxicity
Nanoparticles are increasingly being used in medicine, cosmetics, food, and manufacturing. However, potential toxicity may...
Advances in nanomaterial-targeted treatment of acute lung injury after burns
Advances in nanomaterial-targeted treatment of acute lung injury after burns
To summarize the mechanisms and pathophysiological features of ALI after burn. To classify the targets for the treatment o...
Exosomes as drug delivery systems in glioma immunotherapy
Exosomes as drug delivery systems in glioma immunotherapy
Recently, the significant benefits of cancer immunotherapy for most cancers have been demonstrated in clinical and preclin...
Engineering nanoparticles-enabled tumor-associated macrophages repolarization and phagocytosis restoration for enhanced cancer immunotherapy
Engineering nanoparticles-enabled tumor-associated macrophages repolarization and phagocytosis restoration for enhanced cancer immunotherapy
Tumor-associated macrophages (TAMs) are pivotal within the immunosuppressive tumor microenvironment (TME), and recently, h...
Single-cell RNA transcriptomic reveal the mechanism of MSC derived small extracellular vesicles against DKD fibrosis
Single-cell RNA transcriptomic reveal the mechanism of MSC derived small extracellular vesicles against DKD fibrosis
Diabetic kidney disease (DKD), a chronic kidney disease, is characterized by progressive fibrosis caused due to persistent...
Targeting SUMOylation with an injectable nanocomposite hydrogel to optimize radiofrequency ablation therapy for hepatocellular carcinoma
Targeting SUMOylation with an injectable nanocomposite hydrogel to optimize radiofrequency ablation therapy for hepatocellular carcinoma
Incomplete radiofrequency ablation (iRFA) in hepatocellular carcinoma (HCC) often leads to local recurrence and distant me...
Recent advances in two-dimensional nanomaterials for sustainable wearable electronic devices
Recent advances in two-dimensional nanomaterials for sustainable wearable electronic devices
The widespread adoption of smart terminals has significantly boosted the market potential for wearable electronic devices....
Exosomes secreted by Fusobacterium nucleatum-infected colon cancer cells transmit resistance to oxaliplatin and 5-FU by delivering hsa_circ_0004085
Exosomes secreted by Fusobacterium nucleatum-infected colon cancer cells transmit resistance to oxaliplatin and 5-FU by delivering hsa_circ_0004085
A large number of Fusobacterium nucleatum (Fn) are present in colorectal cancer (CRC) tissues of patients who relapse afte...
Maternal fiber-rich diet promotes early-life intestinal development in offspring through milk-derived extracellular vesicles carrying miR-146a-5p
Maternal fiber-rich diet promotes early-life intestinal development in offspring through milk-derived extracellular vesicles carrying miR-146a-5p
The intestinal development in early life is profoundly influenced by multiple biological components of breast milk, in whi...
Exosome lncRNA IFNG-AS1 derived from mesenchymal stem cells of human adipose ameliorates neurogenesis and ASD-like behavior in BTBR mice
Exosome lncRNA IFNG-AS1 derived from mesenchymal stem cells of human adipose ameliorates neurogenesis and ASD-like behavior in BTBR mice
The transplantation of exosomes derived from human adipose-derived mesenchymal stem cells (hADSCs) has emerged as a prospe...
Dual peptides-modified cationic liposomes for enhanced Lung cancer gene therapy by a gap junction regulating strategy
Dual peptides-modified cationic liposomes for enhanced Lung cancer gene therapy by a gap junction regulating strategy
Gene therapy for lung cancer has emerged as a novel tumor-combating strategy for its superior tumor specificity, low syste...
Nanogels with covalently bound and releasable trehalose for autophagy stimulation in atherosclerosis
Nanogels with covalently bound and releasable trehalose for autophagy stimulation in atherosclerosis
Atherosclerosis, cholesterol-driven plaque formation in arteries, is a complex multicellular disease which is a leading ca...
Investigation of nanotopography on SOCE mediated cell migration via live-cell
Investigation of nanotopography on SOCE mediated cell migration via live-cell
The exploration of cell response to nanotopography has attracted considerable attentions for years. This article focuses o...
Stem cell-derived small extracellular vesicles embedded into methacrylated hyaluronic acid wound dressings accelerate wound repair in a pressure model of diabetic ulcer
Stem cell-derived small extracellular vesicles embedded into methacrylated hyaluronic acid wound dressings accelerate wound repair in a pressure model of diabetic ulcer
Over the past years, the development of innovative smart wound dressings is revolutionizing wound care management and rese...
Identifying tumor cell-released extracellular vesicles as biomarkers for breast cancer diagnosis by a three-dimensional hydrogel-based electrochemical immunosensor
Identifying tumor cell-released extracellular vesicles as biomarkers for breast cancer diagnosis by a three-dimensional hydrogel-based electrochemical immunosensor
Tumor cell-released LC3+ extracellular vesicles (LC3+ EVs) participate in immunosuppression during autophagy and contribut...
Visualization of photothermal therapy by semiconducting polymer dots mediated photoacoustic detection in NIR II
Visualization of photothermal therapy by semiconducting polymer dots mediated photoacoustic detection in NIR II
Visualization of photothermal therapy mediated by photothermal transduction agents (PTAs) is important to promote individu...
Mesenchymal stem cells-derived extracellular vesicles protect against oxidative stress-induced xenogeneic biological root injury via adaptive regulation of the PI3K/Akt/NRF2 pathway
Mesenchymal stem cells-derived extracellular vesicles protect against oxidative stress-induced xenogeneic biological root injury via adaptive regulation of the PI3K/Akt/NRF2 pathway
Xenogeneic extracellular matrices (xECM) for cell support have emerged as a potential strategy for addressing the scarcity...
Correction: Injectable hydrogel loaded with lysed OK-432 and doxorubicin for residual liver cancer after incomplete radiofrequency ablation
Correction: Injectable hydrogel loaded with lysed OK-432 and doxorubicin for residual liver cancer after incomplete radiofrequency ablation
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Nano-modulators with the function of disrupting mitochondrial Ca2+ homeostasis and photothermal conversion for synergistic breast cancer therapy
Nano-modulators with the function of disrupting mitochondrial Ca2+ homeostasis and photothermal conversion for synergistic breast cancer therapy
Breast cancer treatment has been a global puzzle, and apoptosis strategies based on mitochondrial Ca2+ overload have attra...
Functionalized MoS2-nanosheets with NIR-Triggered nitric oxide delivery and photothermal activities for synergistic antibacterial and regeneration-promoting therapy
Functionalized MoS2-nanosheets with NIR-Triggered nitric oxide delivery and photothermal activities for synergistic antibacterial and regeneration-promoting therapy
Bacterial infection in skin and soft tissue has emerged as a critical concern. Overreliance on antibiotic therapy has led ...
Ropivacaine-loaded hydrogels for prolonged relief of chemotherapy-induced peripheral neuropathic pain and potentiated chemotherapy
Ropivacaine-loaded hydrogels for prolonged relief of chemotherapy-induced peripheral neuropathic pain and potentiated chemotherapy
Chemotherapy can cause severe pain for patients, but there are currently no satisfactory methods of pain relief. Enhancing...
Visualization of microRNA therapy in cancers delivered by small extracellular vesicles
Visualization of microRNA therapy in cancers delivered by small extracellular vesicles
MicroRNA (miRNA) delivery by extracellular vesicles (EVs) has recently inspired tremendous developments in cancer treatmen...
Extracellular vesicle-derived silk fibroin nanoparticles loaded with MFGE8 accelerate skin ulcer healing by targeting the vascular endothelial cells
Extracellular vesicle-derived silk fibroin nanoparticles loaded with MFGE8 accelerate skin ulcer healing by targeting the vascular endothelial cells
Reduced supplies of oxygen and nutrients caused by vascular injury lead to difficult-to-heal pressure ulcers (PU) in clini...
Extracellular vesicles in venous thromboembolism and pulmonary hypertension
Extracellular vesicles in venous thromboembolism and pulmonary hypertension
Venous thromboembolism (VTE) is a multifactorial disease, and pulmonary hypertension (PH) is a serious condition character...
Biomimetic composite hydrogel promotes new bone formation in rat bone defects through regulation of miR-19b-3p/WWP1 axis by loaded extracellular vesicles
Biomimetic composite hydrogel promotes new bone formation in rat bone defects through regulation of miR-19b-3p/WWP1 axis by loaded extracellular vesicles
This study aims to investigate the mechanism by which biomimetic composite hydrogels loaded with bone marrow mesenchymal s...
Colchicine delivered by a novel nanoparticle platform alleviates atherosclerosis by targeted inhibition of NF-κB/NLRP3 pathways in inflammatory endothelial cells
Colchicine delivered by a novel nanoparticle platform alleviates atherosclerosis by targeted inhibition of NF-κB/NLRP3 pathways in inflammatory endothelial cells
Atherosclerosis, a chronic inflammatory disease characterized by arterial plaque formation, is one of the most prominent c...
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