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Interplay between Maternal Nutrition and Epigenetic Programming on Offspring Hypertension
Interplay between Maternal Nutrition and Epigenetic Programming on Offspring Hypertension
Hypertension is a global epidemic with nearly half of the world's adult population being defined as having a blood pressur...
Vitamin D3 mitigates type 2 diabetes induced by a high carbohydrate-high fat diet in rats: role of the purinergic system
Vitamin D3 mitigates type 2 diabetes induced by a high carbohydrate-high fat diet in rats: role of the purinergic system
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease in which impaired insulin sensitivity in peripheral tissues...
Nutrient composition of different energy-restricted diets determines plasma endocannabinoid profiles and adipose tissue DAGL-α expression; a 12-week randomized controlled trial in subjects with abdominal obesity
Nutrient composition of different energy-restricted diets determines plasma endocannabinoid profiles and adipose tissue DAGL-α expression; a 12-week randomized controlled trial in subjects with abdominal obesity
The endocannabinoid system (ECS) is dysregulated during obesity and metabolic disorders. Weight loss favours the re-establ...
Chronobiotics, satiety signaling, and clock gene expression interplay
Chronobiotics, satiety signaling, and clock gene expression interplay
Living organisms present changes in their metabolism throughout the day, which are regulated by a mechanism known as the c...
Molecular mechanism and therapeutic significance of essential amino acids in metabolically associated fatty liver disease
Molecular mechanism and therapeutic significance of essential amino acids in metabolically associated fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) is a complex whole-body disease primarily characterized by hepatic lipid accumul...
Butyrate reduction and HDAC4 increase underlie maternal high fructose-induced metabolic dysfunction in hippocampal astrocytes in female rats
Butyrate reduction and HDAC4 increase underlie maternal high fructose-induced metabolic dysfunction in hippocampal astrocytes in female rats
Malnutrition during fetal and infant development [1] could lead to diseases in adulthood through epigenetic mechanisms kno...
Moderate replacement of fish oil with palmitic acid-stimulated mitochondrial fusion promotes β-oxidation by Mfn2 interacting with Cpt1α via its GTPase-domain
Moderate replacement of fish oil with palmitic acid-stimulated mitochondrial fusion promotes β-oxidation by Mfn2 interacting with Cpt1α via its GTPase-domain
Hepatic steatosis is characterized by excessive hepatic lipid accumulation, and it has become a widespread issue worldwide...
A very-low carbohydrate content in a high-fat diet modifies the plasma metabolome and impacts systemic inflammation and experimental atherosclerosis
A very-low carbohydrate content in a high-fat diet modifies the plasma metabolome and impacts systemic inflammation and experimental atherosclerosis
Cardiovascular diseases (CVD) are the leading cause of death globally; about 659,000 people in the United States die from ...
Identification of potential pathogenic hepatic super-enhancers regulatory network in high-fat diet induced hyperlipidemia
Identification of potential pathogenic hepatic super-enhancers regulatory network in high-fat diet induced hyperlipidemia
A chronically high-fat diet (HFD) can cause disorders in lipid metabolism, leading to metabolic syndromes such as obesity,...
Fructose dose-dependently influences colon barrier function by regulation of some main physical, immune, and biological factors in rats
Fructose dose-dependently influences colon barrier function by regulation of some main physical, immune, and biological factors in rats
Fructose is a major component of Western diets but is increasing in China due to the agricultural and industrial developme...
Alginate oligosaccharide alleviates vascular aging by upregulating glutathione peroxidase 7
Alginate oligosaccharide alleviates vascular aging by upregulating glutathione peroxidase 7
Volume 126, April 2024, 109578Author links open overlay panel, , , , , , AbstractAlginate oligosaccharide (AOS) may delay ...
Very low-carbohydrate diet with higher protein ratio improves lipid metabolism and inflammation in rats with diet-induced nonalcoholic fatty liver disease
Very low-carbohydrate diet with higher protein ratio improves lipid metabolism and inflammation in rats with diet-induced nonalcoholic fatty liver disease
The global prevalence of nonalcoholic fatty liver disease (NAFLD) is approximately 15–30% [1]. Unhealthy dietary habits an...
Lipids and lipid signaling molecules in human milk and infant formula, a chemical characterization of relevant biochemical components
Lipids and lipid signaling molecules in human milk and infant formula, a chemical characterization of relevant biochemical components
Volume 126, April 2024, 109580Author links open overlay panel, , , , , AbstractBreastfeeding is the gold standard in infan...
Calorie restriction mimetic, resveratrol, attenuates hepatic ischemia and reperfusion injury through enhancing efferocytosis of macrophages via AMPK/STAT3/S1PR1 pathway
Calorie restriction mimetic, resveratrol, attenuates hepatic ischemia and reperfusion injury through enhancing efferocytosis of macrophages via AMPK/STAT3/S1PR1 pathway
Hepatic ischemia reperfusion injury (HIRI) is a common and inevitable pathological consequence in clinical liver surgeries...
Dietary purple potato supplement attenuates DSS-induced colitis in mice: impact on mitochondrial function
Dietary purple potato supplement attenuates DSS-induced colitis in mice: impact on mitochondrial function
Inflammatory bowel disease (IBD) is characterized by chronic inflammation in gastrointestinal tract, which is often accomp...
Thinned young apple powder prevents obesity-induced neuronal apoptosis via improving mitochondrial function of cerebral cortex in mice
Thinned young apple powder prevents obesity-induced neuronal apoptosis via improving mitochondrial function of cerebral cortex in mice
The rising prevalence of obesity has become a worldwide severe public health problem [1,2]. In recent years, a number of s...
Creatine supplementation with exercise reduces α-synuclein oligomerization and necroptosis in Parkinson's disease mouse model
Creatine supplementation with exercise reduces α-synuclein oligomerization and necroptosis in Parkinson's disease mouse model
Parkinson's disease (PD) is a common neurodegenerative disorder characterized by gradual and irreversible loss of dopamine...
All-trans retinoic acid induces lipophagy through the activation of the AMPK-Beclin1 signaling pathway and reduces Rubicon expression in adipocytes
All-trans retinoic acid induces lipophagy through the activation of the AMPK-Beclin1 signaling pathway and reduces Rubicon expression in adipocytes
Volume 126, April 2024, 109589Author links open overlay panel, , , , , , , , , , , , AbstractLipophagy is defined as a lip...
Nutrient-epigenome interactions: Implications for personalized nutrition against aging-associated diseases
Nutrient-epigenome interactions: Implications for personalized nutrition against aging-associated diseases
Over the past few decades, the global average life expectancy has considerably increased, reaching approximately 60 years....
Anti-obesity effect of butyrate links to modulation of gut microbiome and epigenetic regulation of muscular circadian clock
Anti-obesity effect of butyrate links to modulation of gut microbiome and epigenetic regulation of muscular circadian clock
Volume 127, May 2024, 109590Author links open overlay panel, , , , , , AbstractThe role of the muscle circadian clock in r...
Fish oil-derived n-3 polyunsaturated fatty acids downregulate aquaporin 9 protein expression of liver and white adipose tissues in diabetic KK mice and 3T3-L1 adipocytes
Fish oil-derived n-3 polyunsaturated fatty acids downregulate aquaporin 9 protein expression of liver and white adipose tissues in diabetic KK mice and 3T3-L1 adipocytes
Triacylglycerol (TG) is the main form of lipid storage and is synthesized by a condensation reaction between nonesterified...
Folate deficiency promotes cervical squamous carcinoma SiHa cells progression by targeting miR-375/FZD4/β-catenin signaling
Folate deficiency promotes cervical squamous carcinoma SiHa cells progression by targeting miR-375/FZD4/β-catenin signaling
Cervical cancer (CC) is the fourth most common and deadliest cancer worldwide [1]. The incidence and mortality of CC are s...
Corrigendum to “EGCG inhibited bladder cancer SW780 cell proliferation and migration both in vitro and in vivo via down-regulation of NF-κB and MMP-9” [Journal of Nutritional Biochemistry 41 (2017) 56–64]
Corrigendum to “EGCG inhibited bladder cancer SW780 cell proliferation and migration both in vitro and in vivo via down-regulation of NF-κB and MMP-9” [Journal of Nutritional Biochemistry 41 (2017) 56–64]
Available online 29 November 2023, 109530Author links open overlay panelKe-Wang Luo a 1, Wei Chen a 1, Wing-Yin Lung a, Xi...
Predictive Model for Vitamin C Levels in Hyperinsulinemic Individuals Based on Age, Sex, Waist Circumference, Low-Density Lipoprotein, and Immune-Associated Serum Proteins
Predictive Model for Vitamin C Levels in Hyperinsulinemic Individuals Based on Age, Sex, Waist Circumference, Low-Density Lipoprotein, and Immune-Associated Serum Proteins
Vitamin C (ascorbic acid) is an important water-soluble antioxidant associated with decreased oxidative stress in type 2 d...
Solanum melongena extract supplementation protected skeletal muscle and brain damage by regulation of BDNF/PGC1α/irisin pathway via brain function-related myokines in high-fat diet induced obese mice
Solanum melongena extract supplementation protected skeletal muscle and brain damage by regulation of BDNF/PGC1α/irisin pathway via brain function-related myokines in high-fat diet induced obese mice
In this study, we investigated the protective effects of SM on skeletal muscle and brain damage by regulation of BDNF/ PGC...
Reduced protein intake and aging affects the sustainment of hematopoiesis by impairing bone marrow mesenchymal stem cells
Reduced protein intake and aging affects the sustainment of hematopoiesis by impairing bone marrow mesenchymal stem cells
Nutritional disorders related to reduced protein intake have a prominent role among the factors that compromise the clinic...
KLF4 down-regulation underlies placental angiogenesis impairment induced by maternal glucose intolerance in late pregnancy
KLF4 down-regulation underlies placental angiogenesis impairment induced by maternal glucose intolerance in late pregnancy
During pregnancy, women face many pregnancy complications that may endanger their physical condition and fetal health, inc...
Low vitamin D during pregnancy is associated with infantile eczema by up-regulation of PI3K/AKT/mTOR signaling pathway and affecting FOXP3 expression: A bidirectional cohort study
Low vitamin D during pregnancy is associated with infantile eczema by up-regulation of PI3K/AKT/mTOR signaling pathway and affecting FOXP3 expression: A bidirectional cohort study
Eczema is a type of skin hypersensitivity that commonly starts in early childhood, typically at age 3–6 months [1]. Eczema...
Folate deficiency promotes cervical squamous carcinoma SiHa cells progression by targeting miR-375/FZD4/β-catenin signaling
Folate deficiency promotes cervical squamous carcinoma SiHa cells progression by targeting miR-375/FZD4/β-catenin signaling
Cervical cancer (CC) is the fourth most common and deadliest cancer worldwide [1]. The incidence and mortality of CC are s...
Alternate-day fasting ameliorated anxiety-like behavior in high-fat diet-induced obese mice
Alternate-day fasting ameliorated anxiety-like behavior in high-fat diet-induced obese mice
Over the past few decades, obesity has become a global public health problem [1], placing a heavy health and economic burd...
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