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Population suppression with dominant female-lethal alleles is boosted by homing gene drive
Population suppression with dominant female-lethal alleles is boosted by homing gene drive
Methods to suppress pest insect populations using genetic constructs and repeated releases of male homozygotes have recent...
GhPME36 aggravates susceptibility to Liriomyza sativae by affecting cell wall biosynthesis in cotton leaves
GhPME36 aggravates susceptibility to Liriomyza sativae by affecting cell wall biosynthesis in cotton leaves
Cotton is an important economic crop and a host of Liriomyza sativae. Pectin methylesterase (PME)-mediated pectin metaboli...
The m6A writer KIAA1429 regulates photoaging progression via MFAP4-dependent collagen synthesis
The m6A writer KIAA1429 regulates photoaging progression via MFAP4-dependent collagen synthesis
N6-Methyladenosine (m6A) methylation, a common form of RNA modification, play an important role in the pathogenesis of var...
The subcellular distribution of miRNA isoforms, tRNA-derived fragments, and rRNA-derived fragments depends on nucleotide sequence and cell type
The subcellular distribution of miRNA isoforms, tRNA-derived fragments, and rRNA-derived fragments depends on nucleotide sequence and cell type
MicroRNA isoforms (isomiRs), tRNA-derived fragments (tRFs), and rRNA-derived fragments (rRFs) represent most of the small ...
Genome-wide analysis reveals transcriptional and translational changes during diapause of the Asian corn borer (Ostrinia furnacalis)
Genome-wide analysis reveals transcriptional and translational changes during diapause of the Asian corn borer (Ostrinia furnacalis)
Diapause, a pivotal phase in the insect life cycle, enables survival during harsh environmental conditions. Unraveling the...
Exonuclease editor promotes precision of gene editing in mammalian cells
Exonuclease editor promotes precision of gene editing in mammalian cells
Many efforts have been made to improve the precision of Cas9-mediated gene editing through increasing knock-in efficiency ...
Insights into the biocontrol and plant growth promotion functions of Bacillus altitudinis strain KRS010 against Verticillium dahliae
Insights into the biocontrol and plant growth promotion functions of Bacillus altitudinis strain KRS010 against Verticillium dahliae
Verticillium wilt, caused by the fungus Verticillium dahliae, is a soil-borne vascular fungal disease, which has caused gr...
Spatio-temporal characterization of phenotypic resistance in malaria vector species
Spatio-temporal characterization of phenotypic resistance in malaria vector species
Malaria, a deadly disease caused by Plasmodium protozoa parasite and transmitted through bites of infected female Anophele...
Dissecting thrombus-directed chemotaxis and random movement in neutrophil near-thrombus motion in flow chambers
Dissecting thrombus-directed chemotaxis and random movement in neutrophil near-thrombus motion in flow chambers
Thromboinflammation is caused by mutual activation of platelets and neutrophils. The site of thromboinflammation is determ...
Drought response revealed by chromatin organization variation and transcriptional regulation in cotton
Drought response revealed by chromatin organization variation and transcriptional regulation in cotton
Cotton is a major world cash crop and an important source of natural fiber, oil, and protein. Drought stress is becoming a...
How much do we know about the function of mammalian genes?
How much do we know about the function of mammalian genes?
The last two decades have seen impressive advances in functional genomics, but we are still a long way from understanding ...
Single-sample network modeling on omics data
Single-sample network modeling on omics data
Modeling networks for single samples can facilitate discoveries in biology that go beyond those found when analyzing an &#...
A muscle exercise research revolution powered by -omics at single cell and nucleus resolution
A muscle exercise research revolution powered by -omics at single cell and nucleus resolution
In the last few years, single cell and single nucleus RNA-sequencing technologies have been leveraged in exercised adult s...
Lessons in immune adaptations to hypoxia revealed by comparative and evolutionary physiology
Lessons in immune adaptations to hypoxia revealed by comparative and evolutionary physiology
Recent findings from comparative and evolutionary physiologists reveal novel insights into the regulation of inflammation ...
Evolution beyond DNA: epigenetic drivers for evolutionary change?
Evolution beyond DNA: epigenetic drivers for evolutionary change?
Epigenetics has been a buzzword in science for many years, but 20 years ago, the idea that epigenetic gene regula...
DNA polymerases in precise and predictable CRISPR/Cas9-mediated chromosomal rearrangements
DNA polymerases in precise and predictable CRISPR/Cas9-mediated chromosomal rearrangements
Recent studies have shown that, owning to its cohesive cleavage, Cas9-mediated CRISPR gene editing outcomes at junctions o...
Imputation strategies for genomic prediction using nanopore sequencing
Imputation strategies for genomic prediction using nanopore sequencing
Genomic prediction describes the use of SNP genotypes to predict complex traits and has been widely applied in humans and ...
Geroprotector drugs and exercise: friends or foes on healthy longevity?
Geroprotector drugs and exercise: friends or foes on healthy longevity?
Physical activity and several pharmacological approaches individually combat age-associated conditions and extend healthy ...
Follicular fluid C3a-peptide promotes oocyte maturation through F-actin aggregation
Follicular fluid C3a-peptide promotes oocyte maturation through F-actin aggregation
Immature cumulus-oocyte complexes are retrieved to obtain mature oocytes by in vitro maturation (IVM), a laboratory tool i...
New chromosome-scale genomes provide insights into marine adaptations of sea snakes (Hydrophis: Elapidae)
New chromosome-scale genomes provide insights into marine adaptations of sea snakes (Hydrophis: Elapidae)
Sea snakes underwent a complete transition from land to sea within the last ~ 15 million years, yet they remai...
Diversity across organisational scale emerges through dispersal ability and speciation dynamics in tropical fish
Diversity across organisational scale emerges through dispersal ability and speciation dynamics in tropical fish
Biodiversity exists at different levels of organisation: e.g. genetic, individual, population, species, and community. The...
Identification of FtfL as a novel target of berberine in intestinal bacteria
Identification of FtfL as a novel target of berberine in intestinal bacteria
Berberine (BBR) is a commonly used anti-intestinal inflammation drug, and its anti-cancer activity has been found recently...
FGF-independent MEK1/2 signalling in the developing foetal testis is essential for male germline differentiation in mice
FGF-independent MEK1/2 signalling in the developing foetal testis is essential for male germline differentiation in mice
Disrupted germline differentiation or compromised testis development can lead to subfertility or infertility and are stron...
Plasmodium yoelii iron transporter PyDMT1 interacts with host ferritin and is required in full activity for malarial pathogenesis
Plasmodium yoelii iron transporter PyDMT1 interacts with host ferritin and is required in full activity for malarial pathogenesis
The rapid reproduction of malaria parasites requires proper iron uptake. However, the process of iron absorption by parasi...
Fruit bats adjust their decision-making process according to environmental dynamics
Fruit bats adjust their decision-making process according to environmental dynamics
One of the main functions of behavioral plasticity lies in the ability to contend with dynamic environments. Indeed, while...
Cisplatin exposure alters tRNA-derived small RNAs but does not affect epimutations in C. elegans
Cisplatin exposure alters tRNA-derived small RNAs but does not affect epimutations in C. elegans
The individual lifestyle and environment of an organism can influence its phenotype and potentially the phenotype of its o...
Ovarian ERβ cistrome and transcriptome reveal chromatin interaction with LRH-1
Ovarian ERβ cistrome and transcriptome reveal chromatin interaction with LRH-1
Estrogen receptor beta (ERβ, Esr2) plays a pivotal role in folliculogenesis and ovulation, yet its exact mechanism of...
Lipid bilayer properties potentially contributed to the evolutionary disappearance of betaine lipids in seed plants
Lipid bilayer properties potentially contributed to the evolutionary disappearance of betaine lipids in seed plants
Many organisms rely on mineral nutrients taken directly from the soil or aquatic environment, and therefore, developed mec...
Different mechanisms of X-ray irradiation-induced male and female sterility in Aedes aegypti
Different mechanisms of X-ray irradiation-induced male and female sterility in Aedes aegypti
Aedes aegypti (Ae. aegypti) is the major vector that transmits many diseases including dengue, Zika, and filariasis in tro...
Muscle miRNAs are influenced by sex at baseline and in response to exercise
Muscle miRNAs are influenced by sex at baseline and in response to exercise
Sex differences in microRNA (miRNA) expression profiles have been found across multiple tissues. Skeletal muscle is one of...