SCI Abstract

search
+
Ugi Three-Component Coupling Strategy for the Synthesis of Bridged Bicyclic Iminosugars
A novel and catalyst-free approach has been accomplished for the synthesis of bridged bicyclic iminosugars through a Ugi 3...
A green and cascade synthesis of functionalized 2-sec.amino-thiophenes from ketene dithioacetals
We have reported the synthesis of pharmacologically valuable tetrasubstituted 2-aminothiophenes through a multi-component ...
Recent advances in visible-light-driven photocatalytic synthesis of biologically active N-heterocycles
Heterocycles that contain nitrogen are a very significant class of chemicals that are employed extensively in medicinal ch...
Iron Catalysis Enables Mild C–Se Bond Formation via Decarboxylative Selenylation
Selenium-containing compounds are pivotal in bioactive molecules, yet efficient C–Se bond formation is of significant inte...
Phenoxysulfonyl Azide: A New Diazo-transfer Reagent for Metal–Free Conversion of Amines to Azides
Phenoxysulfonyl azide (PSA, 1) was synthesized from 1,1'-sulfonylbis(2-methyl-1H-imidazole) (2) and studied for its di...
Base-Promoted Tandem Synthesis of Nitrogen-Containing Compounds: MN(SiMe₃)₂ as Potential Nitrogen Sources
The metal-silylamides [MN(SiMe₃)₂, M = Li, Na, and K] are widely used Brønsted bases and have become among the most p...
Molybdenum Catalyzed Acceptorless Dehydrogenative Approach for Quinoline Synthesis Using Amino Alcohol
We report here bidentate phosphine-ligand based molybdenum π-allyl complex [Mo(CO)2(η3-C3H5)(DPPE)Cl] (Mo-1; DPPE =) in th...
Synthesis and Evaluation of Naphthoquinone-based Probes for Activity-based Protein Profiling of Oxidoreductases
Activity-based protein profiling (ABPP) has become a highly valuable proteomic technique over the past decades especially ...
Silver-Catalyzed Synthesis of Polyfunctionalized 1,7- and 2,7- Benzonaphthyridine Scaffolds and their Access to Perlolidine Derivatives
A regio- and chemoselective silver-catalyzed one-pot synthesis of benzo[b][1,7]- and benzo[c][2,7]-naphthyridines has been...
Co(III)-catalyzed allylation reaction of 2-alkenylpyridines with 2-vinylaziridines: access to 1,4-dienes
A Cp*(CO)CoI2-catalyzed C–H allylation of 2-alkenylpyridines with 2-vinylaziridines is described. This method provides an ...
Pyreno-1,2,4-Triazines as Multifunctional Luminogenic Click Reagents
Several examples of 1,2,4-triazines that contain a pyrene fragment attached to the C5 position and a carbonyl functional g...
Chimeric enediyne for targeted degradation of tumor-associated protein
Protein-radical-oxidation targeting enediyne chimera (PROTEC) comprising an enediyne warhead and a protein-targeting moiet...
Transition-metal and Photocatalyst-free Oxidative Cleavage of Aryl alkynes with PIDA/Iminoiodinanes in Visible Light
We report a transition-metal and photocatalyst-free method for the oxidative cleavage of aryl alkynes using phenyliodine d...
Tumor-targeted fluorescent probes for the detection of hNQO1 in cancer cells
Fluorescent probes for single analyte might produce 'false-positive' signals because the levels of the biomarkers ...
Synthesis of naphth[2,1-a]azulenes via [8 + 2] cycloaddition of 2Hcyclohepta[b]furan-2-ones, and their reactivity, optical, and structural properties
A concise and efficient synthetic route to naphth[2,1-a]azulenes was developed via [8 + 2] cycloaddition of 2Hcyclohepta[b...
Selective Electrochemical Trifluoromethylation of Arylamide-or Aryl-substituted Pyrrole Derivatives †
A selective electrochemical trifluoromethylation reaction for pyrroles, particularly those containing additional aryl grou...
Stereoselective synthesis of a KRASG12C inhibitor with quinoline-piperazine scaffold
We developed a novel synthetic route for the KRASG12C inhibitor, focusing on the efficient construc-tion of its central qu...
PIDA-Mediated Synthesis of Kynurenine Derivatives by Oxidative Fragmentation of Tryptophan Scaffold
Kynurenine metabolite is derived from aromatic amino acid tryptophan and its chemical synthesis has been sought for unders...
Synthesis and stability of collagen mimetic peptides featuring δ-heteroatom-substituted prolines
We describe the first investigation of collagen mimetic peptides harboring proline surrogates with heteroatoms at the δ-po...
A MnCl2 Catalyzed Synthesis of Aldehydes from Organohalides by Using Samarium Metal in DMF
Catalyzed by MnCl2, a novel coupling reaction between organohalides and N,N-dimethylformamide (DMF) was investigated in th...
Artemselenoids A−H, eight guaiane-type sesquiterpenoid dimers from Artemisia selengensis and their antihepatoma activities
Eight undescribed guaiane-type sesquiterpenoid dimers (GSDs), artemselenoids A−H (1−8), together with nine known GSDs (9−1...
Phosphinylation/Cyclization of Propynolaldehydes to Isobenzo- furanylic Phosphine Oxides Displaying AIE Properties
Investigating organic reactions to synthesize novel molecules that exhibit aggregation-induced emission (AIE) characterist...
Energy Transfer Mediated Carbonylimination of Alkenes Using Bifunctional Reagent
A photoinduced EnT-mediated generation of acyl radicals has been accomplished using rationally designed acyl oxime ethers ...
Total Synthesis of (±)-Halichonine B
The stereocontrolled total synthesis of (±)-halichonine B was achieved in 18 steps for the longest linear sequence. T...
Brønsted Acid-Catalyzed Synthesis of Sulfinamidines and Sulfinimidate Esters through Electrophilic Fluorination and Substitution
In this work, we present an innovative Brønsted acid-catalyzed approach for the concurrent preparation of sulfinamidi...
A β-Hairpin Peptide Derived from Aβ Forms Different Oligomers in the Crystal State and in Aqueous Solution
The supramolecular assembly of amyloid β into soluble oligomers is critical Alzheimer’s disease (AD) progression. Soluble ...
Computational Exploration of Vinyl Sulfoxonium Ylide Chemistry
This review comprehensively examines the computational techniques employed to elucidate the reactivity, selectivity, and m...
Selenium-catalyzed Allylic C-H Phosphoramidation of Alkenes
We report herein a synthesis of allylic phosphoramidates from alkenes by selenium-catalyzed allylic C-H derivatization. Th...
Total synthesis and structure–antifouling activity relationship of scabrolide F
An efficient synthetic strategy for scabrolide F (7), a norcembranolide diterpene that was isolated from the Taiwanese sof...
Synthesis, characterization and photophysical studies of dual emissive base-modified fluorescent nucleosides
A straightforward and efficient methodology has been employed for the synthesis of a diverse set of base-modified fluoresc...
Load More
format_indent_increase