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Genetics
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Humanized Drosophila Model of the Meier-Gorlin Syndrome Reveals Conserved and Divergent Features of the Orc6 Protein [Genome Integrity and Transmission]
DNA replication is fundamentally important for tissue development, growth, and homeostasis. Impairments of the DNA replica...
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Variation in Genetic Relatedness Is Determined by the Aggregate Recombination Process [Statistical Genetics and Genomics]
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Genetics
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Counteracting Environmental Chemicals with Coenzyme Q10: An Educational Primer for Use with "Antioxidant CoQ10 Restores Fertility by Rescuing Bisphenol A-Induced Oxidative DNA Damage in the Caenorhabditis elegans Germline" [Primer]
Bisphenol A and toxicology: a short historyToxicology is a multidisciplinary science in which the adverse effects of toxic...
Genetics
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Ectopic Expression of a Maize Gene Is Induced by Composite Insertions Generated Through Alternative Transposition [Gene Expression]
AbstractTransposable elements (TEs) are DNA sequences that can mobilize and proliferate throughout eukaryotic genomes. Pre...
Genetics
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Suppressors of mRNA Decapping Defects Restore Growth Without Major Effects on mRNA Decay Rates or Abundance [Gene Expression]
EUKARYOTES share two major messenger RNA (mRNA) decay pathways that are both carried out by exonucleolytic digestion. mRNA...
Genetics
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A Conserved NRDE-2/MTR-4 Complex Mediates Nuclear RNAi in Caenorhabditis elegans [Gene Expression]
AbstractSmall regulatory RNAs, such as small interfering RNAs (siRNAs) and PIWI-interacting RNAs, regulate splicing, trans...
Genetics
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John W. (Jan) Drake: A Biochemical View of a Geneticist Par Excellence [Perspectives]
AbstractJohn W. Drake died 02-02-2020, a mathematical palindrome, which he would have enjoyed, given his love of “word pla...
Genetics
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Identification of Escherichia coli Host Genes That Influence the Bacteriophage Lambda ({lambda}) T4rII Exclusion (Rex) Phenotype [Cellular Genetics]
AbstractThe T4rII exclusion (Rex) phenotype is the inability of T4rII mutant bacteriophage to propagate in hosts (Escheric...
Genetics
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Hmx3a Has Essential Functions in Zebrafish Spinal Cord, Ear and Lateral Line Development [Developmental and Behavioral Genetics]
HOMEOBOX-containing genes, and the homeodomain-containing transcription factors that they encode, have crucial functions i...
Genetics
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Survival Following Traumatic Brain Injury in Drosophila Is Increased by Heterozygosity for a Mutation of the NF-{kappa}B Innate Immune Response Transcription Factor Relish [Cellular Genetics]
TRAUMATIC brain injury (TBI) affects 1.7 million people in the USA annually and is one of the leading causes of death and ...
Genetics
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Plasma Membrane Fusion Is Specifically Impacted by the Molecular Structure of Membrane Sterols During Vegetative Development of Neurospora crassa [Cellular Genetics]
AbstractCell-to-cell fusion is crucial for the development and propagation of most eukaryotic organisms. Despite this impo...
Genetics
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The Broad Transcription Factor Links Hormonal Signaling, Gene Expression, and Cellular Morphogenesis Events During Drosophila Imaginal Disc Development [Developmental and Behavioral Genetics]
TISSUE morphogenesis is required for the elaboration of the body axis and organs during metazoan development. In some cont...
Genetics
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Detecting Selection from Linked Sites Using an F-Model [Population and Evolutionary Genetics]
AbstractAllele frequencies vary across populations and loci, even in the presence of migration. While most differences may...
Genetics
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A Model of Indel Evolution by Finite-State, Continuous-Time Machines [Population and Evolutionary Genetics]
AbstractWe introduce a systematic method of approximating finite-time transition probabilities for continuous-time inserti...
Genetics
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Distinct Functions in Regulation of Meiotic Crossovers for DNA Damage Response Clamp Loader Rad24 (Rad17) and Mec1(ATR) Kinase [Corrigendum]
In the article by M. Shinohara, D. K. Bishop, and A. Shinohara (Genetics, 213: 1255–1269) entitled “Distinct Functions in ...
Genetics
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Reviewer Index [Reviewer Index]
Below is a list of individuals who have reviewed manuscripts for GENETICS during the preparation of volumes 214, 215, and ...
Genetics
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How Good Are Predictions of the Effects of Selective Sweeps on Levels of Neutral Diversity? [Population and Evolutionary Genetics]
MAYNARD SMITH and Haigh (1974) introduced the concept of hitchhiking into population genetics, showing how the spread of a...
Genetics
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