Sisignano M, Baron R, Scholich K, Geisslinger G. Mechanism-based treatment for chemotherapy-induced peripheral neuropathic pain. Nat Rev Neurol. 2014;10:694–707.

Article  CAS  PubMed  Google Scholar 

Flatters SJL, Dougherty PM, Colvin LA. Clinical and preclinical perspectives on chemotherapy-induced peripheral neuropathy (CIPN): a narrative review. Br J Anaesth. 2017;119:737–49.

Article  CAS  PubMed  Google Scholar 

Colvin LA. Chemotherapy-induced peripheral neuropathy: where are we now? Pain. 2019;160(Suppl 1):S1–10.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kim JH, Dougherty PM, Abdi S. Basic science and clinical management of painful and non-painful chemotherapy-related neuropathy. Gynecol Oncol. 2015;136:453–9.

Article  PubMed  PubMed Central  Google Scholar 

Kirksey MA, Haskins SC, Cheng J, Liu SS. Local anesthetic peripheral nerve block adjuvants for prolongation of analgesia: a systematic qualitative review. PLoS ONE. 2015;10: e0137312.

Article  PubMed  PubMed Central  Google Scholar 

Ventham NT, Hughes M, O’Neill S, Johns N, Brady RR, Wigmore SJ. Systematic review and meta-analysis of continuous local anaesthetic wound infiltration versus epidural analgesia for postoperative pain following abdominal surgery. Br J Surg. 2013;100:1280–9.

Article  CAS  PubMed  Google Scholar 

Gupta A. Wound infiltration with local anaesthetics in ambulatory surgery. Curr Opin Anaesthesiol. 2010;23:708–13.

Article  PubMed  Google Scholar 

Waldinger R, Weinberg G, Gitman M. Local anesthetic toxicity in the geriatric population. Drugs Aging. 2020;37:1–9.

Article  PubMed  Google Scholar 

Roberson DP, Binshtok AM, Blasl F, Bean BP, Woolf CJ. Targeting of sodium channel blockers into nociceptors to produce long-duration analgesia: a systematic study and review. Br J Pharmacol. 2011;164:48–58.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen S, Yao W, Wang H, Wang T, Xiao X, Sun G, Yang J, Guan Y, Zhang Z, Xia Z, et al. Injectable electrospun fiber-hydrogel composite sequentially releasing clonidine and ropivacaine for prolonged and walking regional analgesia. Theranostics. 2022;12:4904–21.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhao ZQ, Zhang BL, Chu HQ, Liang L, Chen BZ, Zheng H, Guo XD. A high-dosage microneedle for programmable lidocaine delivery and enhanced local long-lasting analgesia. Biomater Adv. 2022;133: 112620.

Article  PubMed  Google Scholar 

Ke P, Qin Y, Shao Y, Han M, Jin Z, Zhou Y, Zhong H, Lu Y, Wu X, Zeng K. Preparation and evaluation of liposome with ropivacaine ion-pairing in local pain management. Drug Dev Ind Pharm. 2022;48:255–64.

Article  CAS  PubMed  Google Scholar 

Wadhawan A, Chatterjee M, Singh G. Present scenario of bioconjugates in cancer therapy: a review. Int J Mol Sci. 2019;20:5243.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Weinberg BD, Blanco E, Gao J. Polymer implants for intratumoral drug delivery and cancer therapy. J Pharm Sci. 2008;97:1681–702.

Article  CAS  PubMed  Google Scholar 

Lu B, Sun L, Yan X, Ai Z, Xu J. Intratumoral chemotherapy with paclitaxel liposome combined with systemic chemotherapy: a new method of neoadjuvant chemotherapy for stage III unresectable non-small cell Lung cancer. Med Oncol. 2015;32:345.

Article  PubMed  Google Scholar 

Walter KA, Tamargo RJ, Olivi A, Burger PC, Brem H. Intratumoral chemotherapy. Neurosurgery. 1995;37:1128–45.

Article  CAS  PubMed  Google Scholar 

Yang L, Wang B, Qiao W, Liu P. A novel combination chemotherapy integrating with intratumoral chemotherapy. Med Hypotheses. 2009;73:334–5.

Article  CAS  PubMed  Google Scholar 

Celikoglu F, Celikoglu SI, Goldberg EP. Bronchoscopic intratumoral chemotherapy of lung cancer. Lung Cancer. 2008;61:1–12.

Article  PubMed  Google Scholar 

Duvillard C, Polycarpe E, Romanet P, Chauffert B. [=Intratumoral chemotherapy: experimental data and applications to head and neck tumors. Ann Otolaryngol Chir Cervicofac. 2007;124:53–60.

Article  CAS  PubMed  Google Scholar 

Ta HT, Dass CR, Dunstan DE. Injectable chitosan hydrogels for localised cancer therapy. J Control Release. 2008;126:205–16.

Article  CAS  PubMed  Google Scholar 

Wolinsky JB, Colson YL, Grinstaff MW. Local drug delivery strategies for cancer treatment: gels, nanoparticles, polymeric films, rods, and wafers. J Control Release. 2012;159:14–26.

Article  CAS  PubMed  Google Scholar 

Huang P, Wang X, Liang X, Yang J, Zhang C, Kong D, Wang W. Nano-, micro-, and macroscale drug delivery systems for cancer immunotherapy. Acta Biomater. 2019;85:1–26.

Article  CAS  PubMed  Google Scholar 

Blanco E, Kessinger CW, Sumer BD, Gao J. Multifunctional micellar nanomedicine for cancer therapy. Exp Biol Med. 2009;234:123–31.

Article  CAS  Google Scholar 

Peer D, Karp JM, Hong S, Farokhzad OC, Margalit R, Langer R. Nanocarriers as an emerging platform for cancer therapy. Nat Nanotechnol. 2007;2:751–60.

Article  CAS  PubMed  Google Scholar 

Cattel L, Ceruti M, Dosio F. From conventional to stealth liposomes: a new Frontier in cancer chemotherapy. J Chemother. 2004;16(Suppl 4):94–7.

Article  CAS  PubMed  Google Scholar 

Lake DE, Hudis CA. High-dose chemotherapy in breast cancer. Drugs. 2004;64:1851–60.

Article  CAS  PubMed  Google Scholar 

Zraik IM, Hess-Busch Y. Management of chemotherapy side effects and their long-term sequelae. Urologe A. 2021;60:862–71.

Article  PubMed  Google Scholar 

Ha H, Lim JH. Managing side effects of cytotoxic chemotherapy in patients with high grade gliomas. Brain Tumor Res Treat. 2022;10:158–63.

Article  PubMed  PubMed Central  Google Scholar 

Chang YC, Liu CL, Chen MJ, Hsu YW, Chen SN, Lin CH, Chen CM, Yang FM, Hu MC. Local anesthetics induce apoptosis in human breast tumor cells. Anesth Analg. 2014;118:116–24.

Article  CAS  PubMed  Google Scholar 

Johnson MZ, Crowley PD, Foley AG, Xue C, Connolly C, Gallagher HC, Buggy DJ. Effect of perioperative lidocaine on metastasis after sevoflurane or ketamine–xylazine anaesthesia for breast tumour resection in a murine model. Br J Anaesth. 2018;121:76–85.

Article  CAS  PubMed  Google Scholar 

Zimmitti G, Soliz J, Aloia TA, Gottumukkala V, Cata JP, Tzeng CW, Vauthey JN. Positive impact of epidural analgesia on oncologic outcomes in patients undergoing resection of colorectal liver metastases. Ann Surg Oncol. 2016;23:1003–11.

Article  PubMed  Google Scholar 

Xing W, Chen DT, Pan JH, Chen YH, Yan Y, Li Q, Xue RF, Yuan YF, Zeng WA. Lidocaine induces apoptosis and suppresses tumor growth in human hepatocellular carcinoma cells in vitro and in a xenograft model in vivo. Anesthesiology. 2017;126:868–81.

Article  CAS  PubMed  Google Scholar 

Dersh D, Phelan JD, Gumina ME, Wang B, Arbuckle JH, Holly J, Kishton RJ, Markowitz TE, Seedhom MO, Fridlyand N, et al. Genome-wide screens identify lineage- and tumor-specific genes modulating MHC-I- and MHC-II-restricted immunosurveillance of human lymphomas. Immunity. 2021;54:116-131.e110.

Article  CAS  PubMed  Google Scholar 

McGranahan N, Rosenthal R, Hiley CT, Rowan AJ, Watkins TBK, Wilson GA, Birkbak NJ, Veeriah S, Van Loo P, Herrero J, et al. Allele-specific HLA loss and immune escape in lung cancer evolution. Cell. 2017;171:1259-1271.e1211.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yamamoto K, Venida A, Yano J, Biancur DE, Kakiuchi M, Gupta S, Sohn ASW, Mukhopadhyay S, Lin EY, Parker SJ, et al. Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I. Nature. 2020;581:100–5.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang J, Zhu S, Tan Q, Cheng D, Dai Q, Yang Z, Zhang L, Li F, Zuo Y, Dai W, et al. Combination therapy with ropivacaine-loaded liposomes and nutrient deprivation for simultaneous cancer therapy and cancer pain relief. Theranostics. 2020;10:4885–99.

Article  CAS  PubMed  PubMed Central