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Insulin granule morphology and crinosome formation in mice lacking the pancreatic β cell-specific phogrin (PTPRN2) gene
Insulin granule morphology and crinosome formation in mice lacking the pancreatic β cell-specific phogrin (PTPRN2) gene
We recently reported that phogrin, also known as IA-2β or PTPRN2, forms a complex with the insulin receptor in pancre...
MOTS-c regulates pancreatic alpha and beta cell functions in vitro
MOTS-c regulates pancreatic alpha and beta cell functions in vitro
The aim of this study is to determine the influence of the mitochondrial open-reading-frame of the twelve S rRNA-c (MOTS-c...
Oxygen levels affect oviduct epithelium functions in air–liquid interface culture
Oxygen levels affect oviduct epithelium functions in air–liquid interface culture
Key reproductive events such as fertilization and early embryonic development occur in the lumen of the oviduct. Since inv...
Optimization of PAS stain and similar Schiff’s based methods for glycogen demonstration in liver tissue
Optimization of PAS stain and similar Schiff’s based methods for glycogen demonstration in liver tissue
Demonstration of glycogen in tissue holds considerable diagnostic relevance across various pathological conditions, partic...
JNK inhibition enhances cell–cell adhesion impaired by desmoglein 3 gene disruption in keratinocytes
JNK inhibition enhances cell–cell adhesion impaired by desmoglein 3 gene disruption in keratinocytes
c-Jun NH2-terminal protein kinase (JNK) and p38 are stress-activated mitogen-activated protein kinases (MAPK) that are pho...
Effectiveness of cannabidiol (CBD) on histopathological changes and gene expression in hepatocellular carcinoma (HCC) model in male rats: the role of Hedgehog (Hh) signaling pathway
Effectiveness of cannabidiol (CBD) on histopathological changes and gene expression in hepatocellular carcinoma (HCC) model in male rats: the role of Hedgehog (Hh) signaling pathway
The third most prevalent malignancy to cause mortality is hepatocellular carcinoma (HCC). The Hedgehog (Hh) signaling path...
From complexity to clarity: unravelling tumor heterogeneity through the lens of tumor microenvironment for innovative cancer therapy
From complexity to clarity: unravelling tumor heterogeneity through the lens of tumor microenvironment for innovative cancer therapy
Despite the tremendous clinical successes recorded in the landscape of cancer therapy, tumor heterogeneity remains a formi...
The crucial role of SETDB1 in structural and functional transformation of epithelial cells during regeneration after intestinal ischemia reperfusion injury
The crucial role of SETDB1 in structural and functional transformation of epithelial cells during regeneration after intestinal ischemia reperfusion injury
Su (var) 3–9, enhancer of seste, trithorax (SET)-domain bifurcated histone lysine methyltransferase (SETDB1) plays a...
Reliable detection of RNA in hippocampus sections of mice by FISH up to a post-mortem delay of 24 h
Reliable detection of RNA in hippocampus sections of mice by FISH up to a post-mortem delay of 24 h
Proteins can be successfully localized in post-mortem (PM) brain tissue sections if the time until PM tissue sampling is n...
Identification of neutrophils and eosinophils in upper airway mucosa with immunofluorescence multiplex image cytometry
Identification of neutrophils and eosinophils in upper airway mucosa with immunofluorescence multiplex image cytometry
Characterization of inflammation in chronic rhinosinusitis with (CRSwNP) and without nasal polyps (CRSsNP) is an ongoing r...
Inhibition of Notch3/Hey1 ameliorates peribiliary hypoxia by preventing hypertrophic hepatic arteriopathy in biliary atresia progression
Inhibition of Notch3/Hey1 ameliorates peribiliary hypoxia by preventing hypertrophic hepatic arteriopathy in biliary atresia progression
Emerging evidence indicates the presence of vascular abnormalities and ischemia in bil...
Increased endocytosis rate and enhanced lysosomal pathway of silica-coated superparamagnetic nanoparticles into M-HeLa cells compared with cultured primary motor neurons
Increased endocytosis rate and enhanced lysosomal pathway of silica-coated superparamagnetic nanoparticles into M-HeLa cells compared with cultured primary motor neurons
The unique properties of superparamagnetic iron oxide nanoparticles (SPIONs) enable their use as magnetic biosensors, targ...
Allyl isothiocyanate regulates oxidative stress, inflammation, cell proliferation, cell cycle arrest, apoptosis, angiogenesis, invasion and metastasis via interaction with multiple cell signaling pathways
Allyl isothiocyanate regulates oxidative stress, inflammation, cell proliferation, cell cycle arrest, apoptosis, angiogenesis, invasion and metastasis via interaction with multiple cell signaling pathways
Cancer growth is a molecular mechanism initiated by genetic and epigenetic modifications that are involved in cell prolife...
Placental progesterone and its receptor in HIV-infected pre-eclamptic women
Placental progesterone and its receptor in HIV-infected pre-eclamptic women
Given the high prevalence of HIV infection and pre-eclampsia (PE) in South Africa, this study evaluated and compared the p...
Editorial: Histochemistry and Cell Biology implements new submission guidelines for image presentation and image analysis
Editorial: Histochemistry and Cell Biology implements new submission guidelines for image presentation and image analysis
Journal “Instructions for authors” typically describe in more or less detail how manuscript figures should be prepared for...
Local fractal dimension of collagen detects increased spatial complexity in fibrosis
Local fractal dimension of collagen detects increased spatial complexity in fibrosis
Increase of collagen content and reorganization characterizes fibrosis but quantifying the latter remains challenging. Spa...
Cleaved caspase-3 is present in the majority of glial cells in the intact rat spinal cord during postnatal life
Cleaved caspase-3 is present in the majority of glial cells in the intact rat spinal cord during postnatal life
Cell death is an essential process that occurs during the development of the central nervous system. Despite the availabil...
Revisiting the development of cerebellar inhibitory interneurons in the light of single-cell genetic analyses
Revisiting the development of cerebellar inhibitory interneurons in the light of single-cell genetic analyses
The present review aims to provide a short update of our understanding of the inhibitory interneurons of the cerebellum. W...
NADH intraperitoneal injection prevents massive pancreatic beta cell destruction in a streptozotocin-induced diabetes in rats
NADH intraperitoneal injection prevents massive pancreatic beta cell destruction in a streptozotocin-induced diabetes in rats
Diabetes mellitus is a chronic metabolic disease characterized by persistent hyperglycemia, revealing a decrease in insuli...
The presence of Mott cells in the lymph nodes of rats with experimental autoimmune encephalomyelitis
The presence of Mott cells in the lymph nodes of rats with experimental autoimmune encephalomyelitis
Mott cells are plasma cells that have multiple spherical Russell bodies packed in their cytoplasm. Russell bodies are dila...
A note to our authors: Histochemistry and Cell Biology implements guidelines for the use of large language models (including ChatGPT)
A note to our authors: Histochemistry and Cell Biology implements guidelines for the use of large language models (including ChatGPT)
The release of the AI chatbot ChatGPT by OpenAI in San Francisco, California, has brought the capabilities of tools known ...
Early growth response 2, a novel target of pelvic organ prolapse, is highly expressed in anterior vaginal wall tissues with pelvic organ prolapse
Early growth response 2, a novel target of pelvic organ prolapse, is highly expressed in anterior vaginal wall tissues with pelvic organ prolapse
Pelvic organ prolapse (POP) is a common disorder among women that negatively affects women’s quality of life. Early ...
The histomorphological and stereological assessment of rat dorsal root ganglion tissues after various types of sciatic nerve injury
The histomorphological and stereological assessment of rat dorsal root ganglion tissues after various types of sciatic nerve injury
Peripheral nerve injuries lead to significant changes in the dorsal root ganglia, where the cell bodies of the damaged axo...
Mesenchymal stem cell transplantation in burn wound healing: uncovering the mechanisms of local regeneration and tissue repair
Mesenchymal stem cell transplantation in burn wound healing: uncovering the mechanisms of local regeneration and tissue repair
Burn injuries pose a significant healthcare burden worldwide, often leading to long-term disabilities and reduced quality ...
Effects of royal jelly on the antisenescence, mitochondrial viability and osteogenic differentiation capacity of umbilical cord-derived mesenchymal stem cells
Effects of royal jelly on the antisenescence, mitochondrial viability and osteogenic differentiation capacity of umbilical cord-derived mesenchymal stem cells
Mesenchymal stem cells (MSCs) are multipotent cells that have the ability to self-renew and regulate paracrine signalling ...
Protective role of estrogen through G-protein coupled receptor 30 in a colitis mouse model
Protective role of estrogen through G-protein coupled receptor 30 in a colitis mouse model
Estrogen and its receptors are involved in the pathogenesis of gastrointestinal diseases such as colitis. However, the rol...
SARS-CoV-2 egress from Vero cells: a morphological approach
SARS-CoV-2 egress from Vero cells: a morphological approach
Despite being extensively studied because of the current coronavirus disease 2019 (COVID-19) pandemic, severe acute respir...
Non-canonical DNA structures in the human ribosomal DNA
Non-canonical DNA structures in the human ribosomal DNA
Non-canonical structures (NCS) refer to the various forms of DNA that differ from the B-conformation described by Watson a...
Labour and premature delivery differentially affect the expression of the endocannabinoid system in the human placenta
Labour and premature delivery differentially affect the expression of the endocannabinoid system in the human placenta
Plasma concentrations of N-arachidonyletholamine (AEA), N-oleoylethanolamide (OEA) and N-palmitoylethanolamide (PEA) incre...
HK-2 cell response to TGF-β highly depends on cell culture medium formulations
HK-2 cell response to TGF-β highly depends on cell culture medium formulations
The immortalized human renal proximal tubular epithelial cell line HK-2 is most commonly used to study renal cell physiolo...
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