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Lipoprotein apheresis: an established therapeutic modality for homozygous familial hypercholesterolemia patients refractory to PCSK9 inhibitors: a case report and literature review
Lipoprotein apheresis: an established therapeutic modality for homozygous familial hypercholesterolemia patients refractory to PCSK9 inhibitors: a case report and literature review
Homozygous familial hypercholesterolemia (HoFH), is a rare genetic disorder characterized by dual mutations in the low-den...
Relationship between serum uric acid levels and pulmonary embolism: an age-based stratified analysis
Relationship between serum uric acid levels and pulmonary embolism: an age-based stratified analysis
The association between uric acid and pulmonary embolism(PE) remains controversial, and there has been limited investigati...
“Y appearance” infarction: caused by essential thrombocythemia
“Y appearance” infarction: caused by essential thrombocythemia
Essential thrombocythemia (ET) is a myeloproliferative malignancy caused by the excessive proliferation of megakaryocytes ...
Monitoring the efficiency of reversal on anti-Xa direct oral anticoagulants using point-of-care viscoelastic testing
Monitoring the efficiency of reversal on anti-Xa direct oral anticoagulants using point-of-care viscoelastic testing
Bleeding events in patients receiving direct oral anticoagulation (DOAC) can be life-threatening even at therapeutic DOAC ...
Role of ticagrelor in the peri-thrombolytic phase for patients with ST-segment elevation myocardial infarction: a comprehensive review
Role of ticagrelor in the peri-thrombolytic phase for patients with ST-segment elevation myocardial infarction: a comprehensive review
Recent years have seen ticagrelor, a potent P2Y12 inhibitor, emerge as a significant advancement in the peri-thrombolytic ...
Efficacy and safety of anticoagulant for treatment and prophylaxis of VTE patients with renal insufficiency: a systemic review and meta-analysis
Efficacy and safety of anticoagulant for treatment and prophylaxis of VTE patients with renal insufficiency: a systemic review and meta-analysis
Patients with venous thromboembolism (VTE) comorbid renal insufficiency (RI) are at higher risk of bleeding and thrombosis...
Thrombosis-related characteristics of pregnant women with antithrombin deficiency, protein C deficiency and protein S deficiency in Japan
Thrombosis-related characteristics of pregnant women with antithrombin deficiency, protein C deficiency and protein S deficiency in Japan
 We previously conducted a primary survey of pregnant women with hereditary thrombophilia based on national surve...
SERPINC1 c.1247dupC: a novel SERPINC1 gene mutation associated with familial thrombosis results in a secretion defect and quantitative antithrombin deficiency
SERPINC1 c.1247dupC: a novel SERPINC1 gene mutation associated with familial thrombosis results in a secretion defect and quantitative antithrombin deficiency
Antithrombin (AT) is an important anticoagulant in hemostasis. We describe here the characterization of a novel AT mutatio...
Association of inherited thrombophilia mutations and their combinations among palestinian women with unexplained recurrent miscarriage
Association of inherited thrombophilia mutations and their combinations among palestinian women with unexplained recurrent miscarriage
Inherited thrombophilia (IT) has a complex pathophysiology and is associated with recurrent miscarriage (RM) by causing pl...
Establishment and validation of a nomogram predicting the risk of deep vein thrombosis before total knee arthroplasty
Establishment and validation of a nomogram predicting the risk of deep vein thrombosis before total knee arthroplasty
This study aimed to analyze the independent risk factors contributing to preoperative DVT in TKA and constructed a predict...
Hemostatic potential of recombinant von Willebrand factor and standard or pegylated extended half-life recombinant factor VIII on thrombus formation under high shear flow
Hemostatic potential of recombinant von Willebrand factor and standard or pegylated extended half-life recombinant factor VIII on thrombus formation under high shear flow
Von Willebrand factor (VWF) and factor VIII (FVIII) complex play a pivotal role in hemostasis. A deficiency or defect of V...
Comparison between canine and porcine models of chronic deep venous thrombosis
Comparison between canine and porcine models of chronic deep venous thrombosis
To first induce chronic deep venous thrombosis in the left iliac veins of canines and porcines and then compare these two ...
Factors associated with venous thromboembolic disease due to failed thromboprophylaxis
Factors associated with venous thromboembolic disease due to failed thromboprophylaxis
Available evidence to identify factors independently associated with failed thromboprophylaxis (FT) in medical patients is...
Safety and efficacy of direct oral anticoagulants in stroke prevention in patients with atrial fibrillation complicated with anemia and/or thrombocytopenia: a retrospective cohort study
Safety and efficacy of direct oral anticoagulants in stroke prevention in patients with atrial fibrillation complicated with anemia and/or thrombocytopenia: a retrospective cohort study
There are limited data about the clinical benefits and harm of direct oral anticoagulants (DOACs) in stroke prevention in ...
A comprehensive model for assessing and classifying patients with thrombotic microangiopathy: the TMA-INSIGHT score
A comprehensive model for assessing and classifying patients with thrombotic microangiopathy: the TMA-INSIGHT score
Thrombotic Microangiopathy (TMA) is a syndrome characterized by the presence of anemia, thrombocytopenia and organ damage ...
Superior sagittal sinus thrombosis in the course of mixed phenotype acute leukaemia treated with acute lymphoblastic leukaemia-like therapy—a case report
Superior sagittal sinus thrombosis in the course of mixed phenotype acute leukaemia treated with acute lymphoblastic leukaemia-like therapy—a case report
Mixed phenotype acute leukaemia (MPAL) is associated with worse overall survival, compared with other acute leukaemias in ...
The antithrombin activity recovery after substitution therapy is associated with improved 28-day mortality in patients with sepsis-associated disseminated intravascular coagulation
The antithrombin activity recovery after substitution therapy is associated with improved 28-day mortality in patients with sepsis-associated disseminated intravascular coagulation
Disseminated intravascular coagulation (DIC) is a common and critical complication in sepsis. Antithrombin activity, which...
Arterial thrombosis triggered by methotrexate-induced hyperhomocysteinemia in a systemic lupus erythematosus patient with antiphospholipid antibodies
Arterial thrombosis triggered by methotrexate-induced hyperhomocysteinemia in a systemic lupus erythematosus patient with antiphospholipid antibodies
Systemic lupus erythematosus (SLE) patients have an increased risk of cardiovascular disease and thrombotic events, and th...
A novel prognostic prediction indicator in patients with acute pulmonary embolism: Naples prognostic score
A novel prognostic prediction indicator in patients with acute pulmonary embolism: Naples prognostic score
Acute pulmonary embolism (APE) is a potentially fatal disease. Early risk stratification is essential to determining appro...
High-resolution magnetic resonance imaging-based radiomic features aid in selecting endovascular candidates among patients with cerebral venous sinus thrombosis
High-resolution magnetic resonance imaging-based radiomic features aid in selecting endovascular candidates among patients with cerebral venous sinus thrombosis
Cerebral venous sinus thrombosis (CVST) can cause sinus obstruction and stenosis, with potentially fatal consequences. Hig...
Causal inference of sex hormone-binding globulin on venous thromboembolism: evidence from Mendelian randomisation
Causal inference of sex hormone-binding globulin on venous thromboembolism: evidence from Mendelian randomisation
Previous cohort studies have shown that exogenous sex hormone use, such as testosterone replacement therapy and oestrogen-...
Robust preimplantation genetic testing of the common F8 Inv22 pathogenic variant of severe hemophilia A using a highly polymorphic multi-marker panel encompassing the paracentric inversion
Robust preimplantation genetic testing of the common F8 Inv22 pathogenic variant of severe hemophilia A using a highly polymorphic multi-marker panel encompassing the paracentric inversion
Hemophilia A (HEMA) is an X-linked bleeding disorder caused by reduced/absent coagulation factor VIII expression, as a res...
A prediction nomogram for deep venous thrombosis risk in patients undergoing primary total hip and knee arthroplasty: a retrospective study
A prediction nomogram for deep venous thrombosis risk in patients undergoing primary total hip and knee arthroplasty: a retrospective study
Deep venous thrombosis (DVT) prediction after total hip and knee arthroplasty remains challenging. Early diagnosis and tre...
The serum lipid profiles in immune thrombocytopenia: Mendelian randomization analysis and a retrospective study
The serum lipid profiles in immune thrombocytopenia: Mendelian randomization analysis and a retrospective study
Immune thrombocytopenia (ITP) is an autoimmune hemorrhagic disease characterized by increased platelet destruction and imp...
Development and validation of a new risk assessment model for immunomodulatory drug-associated venous thrombosis among Chinese patients with multiple myeloma
Development and validation of a new risk assessment model for immunomodulatory drug-associated venous thrombosis among Chinese patients with multiple myeloma
Individuals with multiple myeloma (MM) receiving immunomodulatory drugs (IMiDs) are at risk of developing venous thromboem...
Sources of bias and limitations of thrombinography: inner filter effect and substrate depletion at the edge of failure algorithm
Sources of bias and limitations of thrombinography: inner filter effect and substrate depletion at the edge of failure algorithm
Fluorogenic thrombin generation (TG) is a global hemostasis assay that provides an overall representation of hemostasis po...
Hyperlipidemia in immune thrombocytopenia: a retrospective study
Hyperlipidemia in immune thrombocytopenia: a retrospective study
Immune thrombocytopenia (ITP) is an autoimmune hemorrhagic disease characterized by low platelet count and bleeding manife...
A retrospective multicenter cohort study of the association between anti-Factor Xa values and death, thromboembolism, and bleeding in patients with critical COVID-19
A retrospective multicenter cohort study of the association between anti-Factor Xa values and death, thromboembolism, and bleeding in patients with critical COVID-19
Patients with critical COVID-19 have a high risk of thromboembolism, but intensified thromboprophylaxis has not been prove...
Evaluation of prothrombotic risk of two PROC hotspot mutations (Arg189Trp and Lys193del) in Chinese population: a retrospective study
Evaluation of prothrombotic risk of two PROC hotspot mutations (Arg189Trp and Lys193del) in Chinese population: a retrospective study
R189W and K193del of protein C (PC) were hotspot mutations in Chinese population with venous thromboembolism (VTE), but al...
GDF15 affects venous thrombosis by promoting EndMT through smad2/p-smad2 pathway
GDF15 affects venous thrombosis by promoting EndMT through smad2/p-smad2 pathway
Endothelial-to-mesenchymal transition (EndMT) is a pathophysiological change in the vascular endothelium commonly seen in ...
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