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Small Interfering RNA Therapy for the Management and Prevention of Hypertension
Small Interfering RNA Therapy for the Management and Prevention of Hypertension
To review currently existing knowledge on a new type of antihypertensive treatment, small interfering RNA (siRNA) targetin...
Guidance for Prescribing Oral Antihypertensive Medications in the Emergency Department
Guidance for Prescribing Oral Antihypertensive Medications in the Emergency Department
To review the most current recommendations regarding assessment and treatment of asymptomatic hypertension treatment in th...
Sodium-Directed Crosstalk Between Immune Cells and Lymphatic Vessels
Sodium-Directed Crosstalk Between Immune Cells and Lymphatic Vessels
The role of the lymphatic system in clearing extravasated fluids, lipid transport, and immune surveillance is well establi...
Approach to Endocrine Hypertension: A Case-Based Discussion
Approach to Endocrine Hypertension: A Case-Based Discussion
Hypertension remains a major chronic disease morbidity across the world, even in the twenty-first century, affecting ͭ...
Does Nocturnal Blood Pressure Matter in Retinal Small Vessels? A Systematic Review and Meta-Analysis of the Literature
Does Nocturnal Blood Pressure Matter in Retinal Small Vessels? A Systematic Review and Meta-Analysis of the Literature
Τhe association between nocturnal blood pressure (BP) and alterations in the retinal microvasculature remains underst...
Factors associated with preeclampsia and the hypertensive disorders of pregnancy amongst Indigenous women of Canada, Australia, New Zealand, and the United States: A systematic review and meta-analysis
Factors associated with preeclampsia and the hypertensive disorders of pregnancy amongst Indigenous women of Canada, Australia, New Zealand, and the United States: A systematic review and meta-analysis
Preeclampsia and the Hypertensive Disorders of Pregnancy (HDP) occur more frequently amongst Indigenous women and can have...
Urinary Biomarkers Of Kidney Function As Predictors Of Cardiovascular Health: A Systematic Review
Urinary Biomarkers Of Kidney Function As Predictors Of Cardiovascular Health: A Systematic Review
The growing burden of cardiovascular diseases has become a significant concern in both adult and youth populations. Urinar...
Hypertension, Obesity, and Target Organ Injury in Children: An Emerging Health Care Crisis
Hypertension, Obesity, and Target Organ Injury in Children: An Emerging Health Care Crisis
To review data regarding the association between hypertension and childhood obesity on target organ damage. We will also r...
“Gut Microbiota as a Therapeutic Target for Hypertension: Challenges and Insights for Future Clinical Applications” “Gut Microbiota and Hypertension Therapy”
“Gut Microbiota as a Therapeutic Target for Hypertension: Challenges and Insights for Future Clinical Applications” “Gut Microbiota and Hypertension Therapy”
Systemic hypertension is a major risk factor for cardiovascular disease and remains challenging to manage despite the wide...
Remote Blood Pressure Monitoring in Pregnancies at Risk of Developing Preeclampsia
Remote Blood Pressure Monitoring in Pregnancies at Risk of Developing Preeclampsia
This review examines the literature on remote blood pressure monitoring (RBPM) for pregnant women at high risk of hyperten...
Secondary Hypertension in Children—Identifying and Investigating at Risk Children
Secondary Hypertension in Children—Identifying and Investigating at Risk Children
We aim to review the most recent literature on demographic features and diagnostic workup of children with secondary hyper...
Sex Difference of Alcoholic Hypertension: Mechanism and Targeted Therapy
Sex Difference of Alcoholic Hypertension: Mechanism and Targeted Therapy
This review provides a critical examination of the sex-specific impact of alcohol consumption on the development and progr...
A Scoping Review of Asymptomatic Hypertension: Definitions, Diagnosis, and Management in the Emergency Department
A Scoping Review of Asymptomatic Hypertension: Definitions, Diagnosis, and Management in the Emergency Department
This scoping review examines the existing literature to reveal consensus or absence thereof regarding the definition and m...
Biomarkers for Predicting Blood Pressure Response to Renal Denervation
Biomarkers for Predicting Blood Pressure Response to Renal Denervation
Since the FDA approved transcatheter renal denervation (RDN) for the treatment of uncontrolled hypertension in 2023, cardi...
Breaking the Barrier: The Role of Gut Epithelial Permeability in the Pathogenesis of Hypertension
Breaking the Barrier: The Role of Gut Epithelial Permeability in the Pathogenesis of Hypertension
To review what intestinal permeability is and how it is measured, and to summarise the current evidence linking altered in...
Epicardial Adipose Tissue Thickness and Preserved Ejection Fraction Heart Failure
Epicardial Adipose Tissue Thickness and Preserved Ejection Fraction Heart Failure
Preserved ejection fraction heart failure and obesity frequently coexist. Whether obesity plays a consistent role in the p...
White Coat Hypertension & Cardiovascular Outcomes
White Coat Hypertension & Cardiovascular Outcomes
This review aims to inform the reader of the complexity of blood pressure responses when comparing blood pressure measured...
Diet to Stop Hypertension: Should Fats be Included?
Diet to Stop Hypertension: Should Fats be Included?
International guidelines emphasize advice to incorporate dietary measures for the prevention and in the management of hype...
Intradialytic Hypertension in Maintenance Hemodialysis
Intradialytic Hypertension in Maintenance Hemodialysis
To summarize the current evidence regarding epidemiology, clinical pathophysiology, and latest therapeutic approaches for ...
Targeting the Brain Leptin-Melanocortin Pathway to Treat Heart Failure
Targeting the Brain Leptin-Melanocortin Pathway to Treat Heart Failure
The role of leptin in regulating cardiac function is still controversial with conflicting results in clinical and preclini...
Importance of the (Pro)renin Receptor in Activating the Renin-Angiotensin System During Normotensive and Preeclamptic Pregnancies
Importance of the (Pro)renin Receptor in Activating the Renin-Angiotensin System During Normotensive and Preeclamptic Pregnancies
For a healthy pregnancy to occur, a controlled interplay between the maternal circulating renin–angiotensin–al...
Insights into Uromodulin and Blood Pressure
Insights into Uromodulin and Blood Pressure
We review the role of uromodulin, a protein exclusively expressed in the kidney, in blood pressure regulation and hyperten...
Hypertension and Cardiovascular Outcomes in Inflammatory and Autoimmune Diseases: A Systematic Review and Meta-analysis
Hypertension and Cardiovascular Outcomes in Inflammatory and Autoimmune Diseases: A Systematic Review and Meta-analysis
This review aimed to investigate the prevalence of hypertension and cardiovascular (CV) complications in various inflammat...
Beneficial Effects of Exercise on Hypertension-Induced Cardiac Hypertrophy in Adolescents and Young Adults
Beneficial Effects of Exercise on Hypertension-Induced Cardiac Hypertrophy in Adolescents and Young Adults
Hypertension-induced cardiac hypertrophy is widely known as a major risk factor for increased cardiovascular morbidity and...
Is There a Role for SGLT2 Inhibitors in Patients with End-Stage Kidney Disease?
Is There a Role for SGLT2 Inhibitors in Patients with End-Stage Kidney Disease?
Chronic kidney disease and end-stage kidney disease (ESKD) are well-established risk factors for cardiovascular disease (C...
Association Between Preeclampsia and Blood Pressure in Offspring: A Systematic Review and Meta-Analysis
Association Between Preeclampsia and Blood Pressure in Offspring: A Systematic Review and Meta-Analysis
Pregnancy-induced preeclampsia is a severe pregnancy complication and preeclampsia has been associated with an increased r...
Machine Learning Algorithms Versus Classical Regression Models in Pre-Eclampsia Prediction: A Systematic Review
Machine Learning Algorithms Versus Classical Regression Models in Pre-Eclampsia Prediction: A Systematic Review
Machine learning (ML) approaches are an emerging alternative for healthcare risk prediction. We aimed to synthesise the li...
Advances on the Experimental Research in Resistant Hypertension
Advances on the Experimental Research in Resistant Hypertension
Resistant Hypertension (RH) poses a significant public health challenge, contributing to increased mortality, cardiovascul...
Considering Adverse Effects of Common Antihypertensive Medications in the ED
Considering Adverse Effects of Common Antihypertensive Medications in the ED
To evaluate the adverse effects of common antihypertensive agents utilized or encountered in the Emergency Department. All...
Strategies for Identifying Patients for Deprescribing of Blood Pressure Medications in Routine Practice: An Evidence Review
Strategies for Identifying Patients for Deprescribing of Blood Pressure Medications in Routine Practice: An Evidence Review
To summarise the evidence regarding which patients might benefit from deprescribing antihypertensive medications. Older pa...
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