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Breaking the Barrier: The Role of Gut Epithelial Permeability in the Pathogenesis of Hypertension
Breaking the Barrier: The Role of Gut Epithelial Permeability in the Pathogenesis of Hypertension
To review what intestinal permeability is and how it is measured, and to summarise the current evidence linking altered in...
Epicardial Adipose Tissue Thickness and Preserved Ejection Fraction Heart Failure
Epicardial Adipose Tissue Thickness and Preserved Ejection Fraction Heart Failure
Preserved ejection fraction heart failure and obesity frequently coexist. Whether obesity plays a consistent role in the p...
White Coat Hypertension & Cardiovascular Outcomes
White Coat Hypertension & Cardiovascular Outcomes
This review aims to inform the reader of the complexity of blood pressure responses when comparing blood pressure measured...
Diet to Stop Hypertension: Should Fats be Included?
Diet to Stop Hypertension: Should Fats be Included?
International guidelines emphasize advice to incorporate dietary measures for the prevention and in the management of hype...
Intradialytic Hypertension in Maintenance Hemodialysis
Intradialytic Hypertension in Maintenance Hemodialysis
To summarize the current evidence regarding epidemiology, clinical pathophysiology, and latest therapeutic approaches for ...
Targeting the Brain Leptin-Melanocortin Pathway to Treat Heart Failure
Targeting the Brain Leptin-Melanocortin Pathway to Treat Heart Failure
The role of leptin in regulating cardiac function is still controversial with conflicting results in clinical and preclini...
Importance of the (Pro)renin Receptor in Activating the Renin-Angiotensin System During Normotensive and Preeclamptic Pregnancies
Importance of the (Pro)renin Receptor in Activating the Renin-Angiotensin System During Normotensive and Preeclamptic Pregnancies
For a healthy pregnancy to occur, a controlled interplay between the maternal circulating renin–angiotensin–al...
Insights into Uromodulin and Blood Pressure
Insights into Uromodulin and Blood Pressure
We review the role of uromodulin, a protein exclusively expressed in the kidney, in blood pressure regulation and hyperten...
Hypertension and Cardiovascular Outcomes in Inflammatory and Autoimmune Diseases: A Systematic Review and Meta-analysis
Hypertension and Cardiovascular Outcomes in Inflammatory and Autoimmune Diseases: A Systematic Review and Meta-analysis
This review aimed to investigate the prevalence of hypertension and cardiovascular (CV) complications in various inflammat...
Beneficial Effects of Exercise on Hypertension-Induced Cardiac Hypertrophy in Adolescents and Young Adults
Beneficial Effects of Exercise on Hypertension-Induced Cardiac Hypertrophy in Adolescents and Young Adults
Hypertension-induced cardiac hypertrophy is widely known as a major risk factor for increased cardiovascular morbidity and...
Is There a Role for SGLT2 Inhibitors in Patients with End-Stage Kidney Disease?
Is There a Role for SGLT2 Inhibitors in Patients with End-Stage Kidney Disease?
Chronic kidney disease and end-stage kidney disease (ESKD) are well-established risk factors for cardiovascular disease (C...
Association Between Preeclampsia and Blood Pressure in Offspring: A Systematic Review and Meta-Analysis
Association Between Preeclampsia and Blood Pressure in Offspring: A Systematic Review and Meta-Analysis
Pregnancy-induced preeclampsia is a severe pregnancy complication and preeclampsia has been associated with an increased r...
Machine Learning Algorithms Versus Classical Regression Models in Pre-Eclampsia Prediction: A Systematic Review
Machine Learning Algorithms Versus Classical Regression Models in Pre-Eclampsia Prediction: A Systematic Review
Machine learning (ML) approaches are an emerging alternative for healthcare risk prediction. We aimed to synthesise the li...
Advances on the Experimental Research in Resistant Hypertension
Advances on the Experimental Research in Resistant Hypertension
Resistant Hypertension (RH) poses a significant public health challenge, contributing to increased mortality, cardiovascul...
Considering Adverse Effects of Common Antihypertensive Medications in the ED
Considering Adverse Effects of Common Antihypertensive Medications in the ED
To evaluate the adverse effects of common antihypertensive agents utilized or encountered in the Emergency Department. All...
Strategies for Identifying Patients for Deprescribing of Blood Pressure Medications in Routine Practice: An Evidence Review
Strategies for Identifying Patients for Deprescribing of Blood Pressure Medications in Routine Practice: An Evidence Review
To summarise the evidence regarding which patients might benefit from deprescribing antihypertensive medications. Older pa...
Resistant Hypertension: Disease Burden and Emerging Treatment Options
Resistant Hypertension: Disease Burden and Emerging Treatment Options
To define resistant hypertension (RHT), review its pathophysiology and disease burden, identify barriers to effective hype...
Genetic Appraisal of RAAS-Associated SNPs: REN (rs16853055), AGT (rs3789678) and ACE (rs4305) in Preeclamptic Women Living with HIV Infection
Genetic Appraisal of RAAS-Associated SNPs: REN (rs16853055), AGT (rs3789678) and ACE (rs4305) in Preeclamptic Women Living with HIV Infection
The primary goal of this review article was to determine whether the three RAAS-associated SNPs, Renin-rs16853055, AGT-rs3...
Update on the Use of Pulse Wave Velocity to Measure Age-Related Vascular Changes
Update on the Use of Pulse Wave Velocity to Measure Age-Related Vascular Changes
Pulse wave velocity (PWV) is an important and well-established measure of arterial stiffness that is strongly ass...
Screening and Management of Pediatric High Blood Pressure—Challenges to Implementing the Clinical Practice Guideline
Screening and Management of Pediatric High Blood Pressure—Challenges to Implementing the Clinical Practice Guideline
Elevated blood pressure (BP) and hypertension in childhood convey risk for hypertension and cardiovascular events in adult...
Effect of Continuous Positive Airway Pressure on Blood Pressure in Patients with Resistant Hypertension and Obstructive Sleep Apnea: An Updated Meta-analysis
Effect of Continuous Positive Airway Pressure on Blood Pressure in Patients with Resistant Hypertension and Obstructive Sleep Apnea: An Updated Meta-analysis
The effect of continuous positive airway pressure (CPAP) on resistant hypertension in patients at high risk with obstructi...
The Role of Obesity in the Development of Preeclampsia
The Role of Obesity in the Development of Preeclampsia
This comprehensive review provides an in-depth exploration of the complex relationship between obesity and preeclampsia (P...
Management of Pulmonary Hypertension in the Context of Heart Failure with Preserved Ejection Fraction
Management of Pulmonary Hypertension in the Context of Heart Failure with Preserved Ejection Fraction
To review the current evidence and modalities for treating pulmonary hypertension (PH) in heart failure with preserved eje...
Managing Hypertension in Older Adults
Managing Hypertension in Older Adults
The population of older adults 60–79 years globally is projected to double from 800 million to 1.6 billion ...
Preeclampsia and the Retina
Preeclampsia and the Retina
This review summarizes key findings relating to the association between preeclampsia and retinal disorders. Preeclampsia i...
Endoplasmic Reticulum Stress in Hypertension and Salt Sensitivity of Blood Pressure
Endoplasmic Reticulum Stress in Hypertension and Salt Sensitivity of Blood Pressure
Hypertension is a principal risk factor for cardiovascular morbidity and mortality, with its severity exacerbated by high ...
Neuroimmunology of Cardiovascular Disease
Neuroimmunology of Cardiovascular Disease
Cardiovascular disease (CVD) is a leading cause of death and chronic disability worldwide. Yet, despite extensive interven...
HEARTS in the Americas: Targeting Health System Change to Improve Population Hypertension Control
HEARTS in the Americas: Targeting Health System Change to Improve Population Hypertension Control
HEARTS in the Americas is the regional adaptation of Global Hearts, the World Health Organization initiative for cardiovas...
Blood–Brain Barrier Dysfunction in Hypertensive Disorders of Pregnancy
Blood–Brain Barrier Dysfunction in Hypertensive Disorders of Pregnancy
The incidence of hypertensive disorders of pregnancy (HDP), especially preeclampsia has increased significantly over the l...
Slow on the Draw—ED Management of Elevated BP in Older Adults
Slow on the Draw—ED Management of Elevated BP in Older Adults
The purpose of this study is to review data surrounding the emergency department management of elevated blood pressure in ...
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