Hyperlipidemia in immune thrombocytopenia: a retrospective study

Yamagishi S, Ohta M, Segawa C, Abe T, Sawada T. A rare case of arteriosclerosis obliterans without prominent risk factors complicated by idiopathic thrombocytopenic purpura. A case report. Angiology. 1996;47(4):413–7.

Article  CAS  PubMed  Google Scholar 

Rodeghiero F. ITP and thrombosis: an intriguing association. Blood Adv. 2017;1(24):2280.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lozano ML, Garabet L, Fernandez-Perez MP, De Los Reyes-Garcia AM, Diaz-Lozano P, Garcia-Barbera N, et al. Platelet activation and neutrophil extracellular trap (NET) formation in immune thrombocytopenia: is there an association? Platelets. 2020;31(7):906–12.

Article  CAS  PubMed  Google Scholar 

Provan D, Arnold DM, Bussel JB, Chong BH, Cooper N, Gernsheimer T, et al. Updated international consensus report on the investigation and management of primary immune thrombocytopenia. Blood Adv. 2019;3(22):3780–817.

Article  PubMed  PubMed Central  Google Scholar 

Stasi R, Evangelista ML, Stipa E, Buccisano F, Venditti A, Amadori S. Idiopathic thrombocytopenic purpura: current concepts in pathophysiology and management. Thromb Haemost. 2008;99(1):4–13.

Article  CAS  PubMed  Google Scholar 

Khellaf M, Michel M, Schaeffer A, Bierling P, Godeau B. Assessment of a therapeutic strategy for adults with severe autoimmune thrombocytopenic purpura based on a bleeding score rather than platelet count. Haematologica. 2005;90(6):829–32.

PubMed  Google Scholar 

Garabet L, Henriksson CE, Lozano ML, Ghanima W, Bussel J, Brodin E, et al. Markers of endothelial cell activation and neutrophil extracellular traps are elevated in immune thrombocytopenia but are not enhanced by thrombopoietin receptor agonists. Thromb Res. 2020;185:119–24.

Article  CAS  PubMed  Google Scholar 

Catala-Lopez F, Corrales I, de la Fuente-Honrubia C, Gonzalez-Bermejo D, Martin-Serrano G, Montero D, et al. Risk of thromboembolism with thrombopoietin receptor agonists in adult patients with thrombocytopenia: systematic review and meta-analysis of randomized controlled trials. Med Clin (Barc). 2015;145(12):511–9.

Article  PubMed  Google Scholar 

Daniel GW, Menis M, Sridhar G, Scott D, Wallace AE, Ovanesov MV, et al. Immune globulins and thrombotic adverse events as recorded in a large administrative database in 2008 through 2010. Transfusion. 2012;52(10):2113–21.

Article  CAS  PubMed  Google Scholar 

Girolami A, de Marinis GB, Bonamigo E, Treleani M, Vettore S. Arterial and venous thromboses in patients with idiopathic (immunological) thrombocytopenia: a possible contributing role of cortisone-induced hypercoagulable state. Clin Appl Thromb Hemost. 2013;19(6):613–8.

Article  PubMed  Google Scholar 

Ryu H, Kim J, Kim D, Lee JE, Chung Y. Cellular and Molecular Links between autoimmunity and lipid metabolism. Mol Cells. 2019;42(11):747–54.

CAS  PubMed  PubMed Central  Google Scholar 

Teague HL, Varghese NJ, Tsoi LC, Dey AK, Garshick MS, Silverman JI, et al. Neutrophil subsets, platelets, and Vascular Disease in Psoriasis. JACC Basic Transl Sci. 2019;4(1):1–14.

Article  PubMed  PubMed Central  Google Scholar 

Skaggs BJ, Hahn BH, McMahon M. Accelerated atherosclerosis in patients with SLE–mechanisms and management. Nat Rev Rheumatol. 2012;8(4):214–23.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Matsuura E, Atzeni F, Sarzi-Puttini P, Turiel M, Lopez LR, Nurmohamed MT. Is atherosclerosis an autoimmune disease? BMC Med. 2014;12:47.

Article  PubMed  PubMed Central  Google Scholar 

Cinoku II, Mavragani CP, Moutsopoulos HM, Atherosclerosis. Beyond the lipid storage hypothesis. The role of autoimmunity. Eur J Clin Invest. 2020;50(2):e13195.

Article  PubMed  Google Scholar 

Palinski W, Tsimikas S. Immunomodulatory effects of statins: mechanisms and potential impact on arteriosclerosis. J Am Soc Nephrol. 2002;13(6):1673–81.

Article  CAS  PubMed  Google Scholar 

Kwak B, Mulhaupt F, Myit S, Mach F. Statins as a newly recognized type of immunomodulator. Nat Med. 2000;6(12):1399–402.

Article  CAS  PubMed  Google Scholar 

Khattri S, Zandman-Goddard G. Statins and autoimmunity. Immunol Res. 2013;56(2–3):348–57.

Article  CAS  PubMed  Google Scholar 

Kong Y, Cao XN, Zhang XH, Shi MM, Lai YY, Wang Y, et al. Atorvastatin enhances bone marrow endothelial cell function in corticosteroid-resistant immune thrombocytopenia patients. Blood. 2018;131(11):1219–33.

Article  CAS  PubMed  Google Scholar 

Xu P, Zhao Y, Yu T, Yu Y, Ni X, Wang H et al. Atorvastatin restores imbalance of cluster of differentiation 4 (CD4)(+) T cells in immune thrombocytopenia in vivo and in vitro. Br J Haematol. 2021.

Provan D, Stasi R, Newland AC, Blanchette VS, Bolton-Maggs P, Bussel JB, et al. International consensus report on the investigation and management of primary immune thrombocytopenia. Blood. 2010;115(2):168–86.

Article  CAS  PubMed  Google Scholar 

Page LK, Psaila B, Provan D, Michael Hamilton J, Jenkins JM, Elish AS, et al. The immune thrombocytopenic purpura (ITP) bleeding score: assessment of bleeding in patients with ITP. Br J Haematol. 2007;138(2):245–8.

Article  PubMed  Google Scholar 

Li C, Sun M, Li R, Wang S, Shao L, Xu M, et al. Association of metformin treatment and outcome in adult patients with ITP and pre-existing T2DM. Br J Haematol. 2022;197(3):367–72.

Article  CAS  PubMed  Google Scholar 

Zeng C, Dubreuil M, LaRochelle MR, Lu N, Wei J, Choi HK, et al. Association of Tramadol with all-cause mortality among patients with osteoarthritis. JAMA. 2019;321(10):969–82.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Neunert CE. Management of newly diagnosed immune thrombocytopenia: can we change outcomes? Hematol Am Soc Hematol Educ Program. 2017;2017(1):400–5.

Article  Google Scholar 

Thrombosis, Hemostasis Group CSoHCMA. [Chinese guideline on the diagnosis and management of adult primary immune thrombocytopenia (version 2020)]. Zhonghua Xue Ye Xue Za Zhi. 2020;41(8):617–23.

Google Scholar 

Hahn BH, Grossman J, Chen W, McMahon M. The pathogenesis of atherosclerosis in autoimmune rheumatic diseases: roles of inflammation and dyslipidemia. J Autoimmun. 2007;28(2–3):69–75.

Article  CAS  PubMed  Google Scholar 

Hubler MJ, Kennedy AJ. Role of lipids in the metabolism and activation of immune cells. J Nutr Biochem. 2016;34:1–7.

Article  CAS  PubMed  Google Scholar 

Bapat SP, Whitty C, Mowery CT, Liang Y, Yoo A, Jiang Z, et al. Obesity alters pathology and treatment response in inflammatory disease. Nature. 2022;604(7905):337–42.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Franchi L, Eigenbrod T, Munoz-Planillo R, Nunez G. The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis. Nat Immunol. 2009;10(3):241–7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Spann NJ, Glass CK. Sterols and oxysterols in immune cell function. Nat Immunol. 2013;14(9):893–900.

Article  CAS  PubMed  Google Scholar 

Namgaladze D, Lips S, Leiker TJ, Murphy RC, Ekroos K, Ferreiros N, et al. Inhibition of macrophage fatty acid beta-oxidation exacerbates palmitate-induced inflammatory and endoplasmic reticulum stress responses. Diabetologia. 2014;57(5):1067–77.

Article  CAS  PubMed  Google Scholar 

Wang N, Tall AR. Cholesterol in platelet biogenesis and activation. Blood. 2016;127(16):1949–53.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Niessen J, Jedlitschky G, Grube M, Bien S, Schwertz H, Ohtsuki S, et al. Human platelets express organic anion-transporting peptide 2B1, an uptake transporter for atorvastatin. Drug Metab Dispos. 2009;37(5):1129–37.

Article  CAS  PubMed  Google Scholar 

Barale C, Frascaroli C, Senkeev R, Cavalot F, Russo I. Simvastatin Effects on inflammation and platelet activation markers in Hypercholesterolemia. Biomed Res Int. 2018;2018:6508709.

Article  PubMed  PubMed Central  Google Scholar 

Blaho VA, Galvani S, Engelbrecht E, Liu C, Swendeman SL, Kono M, et al. HDL-bound sphingosine-1-phosphate restrains lymphopoiesis and neuroinflammation. Nature. 2015;523(7560):342–6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu C, Cheng L, Ji L, Li F, Zhan Y, Wu B, et al. Intestinal microbiota dysbiosis play a role in pathogenesis of patients with primary immune thrombocytopenia. Thromb Res. 2020;190:11–9.

Article  CAS  PubMed 

留言 (0)

沒有登入
gif