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OXYGEN CONSUMPTION AS AN EARLY WARNING SYSTEM IN THE CRITICALLY ILL
Introduction: In this study, we assessed whether changes in oxygen consumption (VO2) and other metab
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ASSOCIATION BETWEEN PLASMA TRANSFUSION AND IN-HOSPITAL MORTALITY IN CRITICALLY ILL PATIENTS WITH SEPSIS-INDUCED COAGULOPATHY
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ANNEXIN A2 FACILITATES NEOVASCULARIZATION TO PROTECT AGAINST MYOCARDIAL INFARCTION INJURY VIA INTERACTING WITH MACROPHAGE YAP AND ENDOTHELIAL INTEGRIN Β3
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INTERFERING HSA_CIRC_0001226 MITIGATES LPS-INDUCED BEAS-2B CELL INJURY BY REGULATING MIR-940/TGFBR2 PATHWAY
Background: Sepsis-associated acute lung injury (SA-ALI) is a serious threat to human health. A grow
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RESPIRATION-RELATED VARIATIONS IN CENTRAL VENOUS PRESSURE AS PREDICTORS OF FLUID RESPONSIVENESS IN SPONTANEOUSLY BREATHING PATIENTS
Objective: The hemodynamic parameters used to accurately predict fluid responsiveness (FR) in sponta
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CIRC_0085323 SILENCING INHIBITS TNF-Α-INDUCED NORMAL HUMAN COLONIC EPITHELIAL CELL INFLAMMATION AND APOPTOSIS THROUGH THE MIR-495-3P/TRAF3 AXIS
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CIRCTDRD9 CONTRIBUTES TO SEPSIS-INDUCED ACUTE LUNG INJURY BY ENHANCING THE EXPRESSION OF RAB10 VIA DIRECTLY BINDING TO MIR-223-3P
Background: The dysregulation of circular RNAs (circRNAs) is involved in various human diseases, inc
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ANALYSIS OF THE RELATIONSHIP BETWEEN EARLY SERUM PHOSPHATE LEVELS AND SHORT-TERM MORTALITY IN SEPTIC PATIENTS: A RETROSPECTIVE STUDY BASED ON MIMIC-IV
Objective: The aim of the study is to explore the impact of early serum phosphate levels on the prog
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THE IL-33/ST2 AXIS PROMOTES ACUTE RESPIRATORY DISTRESS SYNDROME BY NATURAL KILLER T CELLS
Acute respiratory distress syndrome (ARDS) is characterized by uncontrolled inflammation, which mani
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BODY TEMPERATURE VARIATION AFTER PACKED CELL TRANSFUSION IN ADULT PATIENTS WITH SEPSIS—WHERE WILL THE PENDULUM STOP?
Background: Critically ill patients with sepsis often require packed cell transfusions (PCTs). Packe
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EFFECT OF EXOSOMES DERIVED FROM BONE MARROW MESENCHYMAL STEM CELLS ON PROGRAMMED CELL DEATH IN BLAST-INDUCED LUNG INJURY IN RATS
Blast lung injuries (BLIs) are frequent because of industrial accidents and terrorist groups. Bone m
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GLOBAL SIGNATURES OF THE MICROBIOME AND METABOLOME DURING HOSPITALIZATION OF SEPTIC PATIENTS
Background: The gut plays an important role in the development of sepsis and acts as one of the poss
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THE EFFECTS OF DNASE I AND LOW-MOLECULAR-WEIGHT HEPARIN IN A MURINE MODEL OF POLYMICROBIAL ABDOMINAL SEPSIS
Introduction: Cell-free DNA (CFDNA) has emerged as a prognostic biomarker in patients with sepsis. C
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THE 19TH CONGRESS OF THE EUROPEAN SHOCK SOCIETY (ESS)
THE 19TH CONGRESS OF THE EUROPEAN SHOCK SOCIETY (ESS) : Shock ...
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MACROPHAGE SWITCHING: POLARIZATION AND MOBILIZATION AFTER TRAUMA
Introduction: Trauma alters the immune response in numerous ways, affecting both the innate and adap
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ALKBH5 ALLEVIATES HYPOXIA POSTCONDITIONING INJURY IN d-GALACTOSE–INDUCED SENESCENT CARDIOMYOCYTES BY REGULATING STAT3
Ischemic postconditioning (I/Post) reduces I/R injury by activating endogenous cardioprotection mech
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RISK OF HOSPITAL MORTALITY IN CRITICALLY ILL PATIENTS WITH TRANSIENT AND PERSISTENT THROMBOCYTOPENIA: A RETROSPECTIVE STUDY
Background: Thrombocytopenia (TP), a common occurrence among patients admitted to the intensive care
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LACTATE IMPAIRS VASCULAR PERMEABILITY BY INHIBITING HSPA12B EXPRESSION VIA GPR81-DEPENDENT SIGNALING IN SEPSIS
Introduction: Sepsis impaired vascular integrity results in multiple organ failure. Circulating lact
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EFFECTS OF 2-METHYL-2-THIAZOLINE ON CIRCULATORY DYNAMICS AND INTESTINAL VASCULAR SYSTEM IN RABBITS WITH ENDOTOXIC SHOCK
We hypothesized that circulatory and jejunal mucosal blood flow would improve after 2-methyl-2thiazo
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HOSPITAL CHARACTERISTICS ARE ASSOCIATED WITH CLINICAL OUTCOMES IN PATIENTS WITH CARDIOGENIC SHOCK
Background: Regionalized systems of care for the management of cardiogenic shock (CS) are increasing
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A 29-MRNA HOST RESPONSE WHOLE-BLOOD SIGNATURE IMPROVES PREDICTION OF 28-DAY MORTALITY AND 7-DAY INTENSIVE CARE UNIT CARE IN ADULTS PRESENTING TO THE EMERGENCY DEPARTMENT WITH SUSPECTED ACUTE INFECTION AND/OR SEPSIS
Background: Risk stratification of emergency department patients with suspected acute infections and
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Necroptosis, Pyroptosis, Ferroptosis in Sepsis and Treatment
As a global major health problem and a leading cause of death, sepsis is defined as a failure of hom
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Selepressin in Septic Shock
Sepsis and septic shock usually show a high mortality rate and frequently need of intensive care uni
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Impaired Lymphocyte Responses in Pediatric Sepsis Vary by Pathogen Type and are Associated with Features of Immunometabolic Dysregulation
Background: Sepsis is the leading cause of death in hospitalized children worldwide. Despite its
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Circular RNA UBAP2 (hsa_circ_0007367) Correlates with Microcirculatory Perfusion and Predicts Outcomes of Cardiogenic Shock Patients Undergoing Extracorporeal Membrane Oxygenation Support
Background: Severe microcirculatory disturbance is common in patients with cardiogenic shock nece
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Exosomal Transfer of DNA Methyl-Transferase mRNA Induces an Immunosuppressive Phenotype in Human Monocytes
Introduction: Survivors of sepsis exhibit persistent immunosuppression. Epigenetic events may be
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Fecal Microbiota Transfer Attenuates Gut Dysbiosis and Functional Deficits After Traumatic Brain Injury
Background: Traumatic brain injury (TBI) is an underrecognized public health threat. Survivors of
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Whole Blood Selective Aortic Arch Perfusion for Exsanguination Cardiac Arrest: Assessing Myocardial Tolerance to the Duration of Cardiac Arrest
Introduction: Selective aortic arch perfusion (SAAP) is an endovascular technique that consists o
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Defining Sepsis Phenotypes—Two Murine Models of Sepsis and Machine Learning
Introduction: The immunobiology defining the clinically apparent differences in response to sepsi
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A Limited Role for AMD3100 Induced Stem Cell Mobilization for Modulation of Thoracic Trauma Outcome
Thoracic trauma is a major cause of mortality due to the associated inflammatory acute respiratory d
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