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Research progress on the therapeutic effects of nanoparticles loaded with drugs against atherosclerosis
Research progress on the therapeutic effects of nanoparticles loaded with drugs against atherosclerosis
Presently, there are many drugs for the treatment of atherosclerosis (AS), among which lipid-lowering, anti-inflammatory, ...
Effect of Prolonged Use of Dronedarone on Recurrence in Patients with Non-Paroxysmal Atrial Fibrillation After Radiofrequency Ablation (DORIS): Rationale and Design of a Randomized Multicenter, Double-Blinded Placebo-Controlled Trial
Effect of Prolonged Use of Dronedarone on Recurrence in Patients with Non-Paroxysmal Atrial Fibrillation After Radiofrequency Ablation (DORIS): Rationale and Design of a Randomized Multicenter, Double-Blinded Placebo-Controlled Trial
Prolonged use of anti-arrhythmic drugs (AAD) beyond the post-ablation blanking period to maintain sinus rhythm has been ad...
Pharmacological Inhibition of P-Rex1/Rac1 Axis Blocked Angiotensin II-Induced Cardiac Fibrosis
Pharmacological Inhibition of P-Rex1/Rac1 Axis Blocked Angiotensin II-Induced Cardiac Fibrosis
Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor-1 (P-Rex1), as one of the members of Rac-GEFs, has ...
Meta-Analysis Evaluating Risk of Hyperkalemia Stratified by Baseline MRA Usage in Patients with Heart Failure Receiving SGLT2 Inhibitors
Meta-Analysis Evaluating Risk of Hyperkalemia Stratified by Baseline MRA Usage in Patients with Heart Failure Receiving SGLT2 Inhibitors
Both mineralocorticoid receptor antagonists (MRAs) and sodium-glucose co-transporter type 2 inhibitors (SGLT2is) have demo...
Epigallocatechin-3-Gallate Inhibits Atrial Fibrosis and Reduces the Occurrence and Maintenance of Atrial Fibrillation and its Possible Mechanisms
Epigallocatechin-3-Gallate Inhibits Atrial Fibrosis and Reduces the Occurrence and Maintenance of Atrial Fibrillation and its Possible Mechanisms
Atrial fibrosis is one of the main causes of the onset and recurrence of atrial fibrillation (AF), for which there is no e...
Acute and Post-Acute COVID-19 Cardiovascular Complications: A Comprehensive Review
Acute and Post-Acute COVID-19 Cardiovascular Complications: A Comprehensive Review
The risk of cardiovascular complications due to SARS-CoV-2 are significantly increased within the first 6 months of the in...
Regulatory T Cells in Pathological Cardiac Hypertrophy: Mechanisms and Therapeutic Potential
Regulatory T Cells in Pathological Cardiac Hypertrophy: Mechanisms and Therapeutic Potential
Pathological cardiac hypertrophy is linked to immune-inflammatory injury, and regulatory T cells (Tregs) play a crucial ro...
Dapagliflozin for Atrial Fibrillation
Dapagliflozin for Atrial Fibrillation
Sodium glucose cotransporter-2 (SGLT2) inhibitors, originally developed for the treat...
Differential Proteomic Profiles of Coronary Serum Exosomes in Acute Myocardial Infarction Patients with or Without Diabetes Mellitus: ANGPTL6 Accelerates Regeneration of Endothelial Cells Treated with Rapamycin via MAPK Pathways
Differential Proteomic Profiles of Coronary Serum Exosomes in Acute Myocardial Infarction Patients with or Without Diabetes Mellitus: ANGPTL6 Accelerates Regeneration of Endothelial Cells Treated with Rapamycin via MAPK Pathways
Delayed re-endothelialization after coronary drug-eluting stent implantation is associated with an increased incidence of ...
The SGLT2i Dapagliflozin Reduces RV Mass Independent of Changes in RV Pressure Induced by Pulmonary Artery Banding
The SGLT2i Dapagliflozin Reduces RV Mass Independent of Changes in RV Pressure Induced by Pulmonary Artery Banding
Sodium glucose linked transporter 2 (SGLT2) inhibition not only reduces morbidity and mortality in patients with diagnosed...
Acute Kidney Injury in Different Anticoagulation Strategies: A Large-Scale Pharmacoepidemiologic Study Using Real-World Data
Acute Kidney Injury in Different Anticoagulation Strategies: A Large-Scale Pharmacoepidemiologic Study Using Real-World Data
Acute kidney injury (AKI) following anticoagulant application has received growing attention as a significant emerging com...
Safety and Effectiveness of Antidysrhythmic Drugs for Pharmacologic Cardioversion of Recent-Onset Atrial Fibrillation: a Systematic Review and Bayesian Network Meta-analysis
Safety and Effectiveness of Antidysrhythmic Drugs for Pharmacologic Cardioversion of Recent-Onset Atrial Fibrillation: a Systematic Review and Bayesian Network Meta-analysis
The available evidence to determine which antidysrhythmic drug is superior for pharmacologic cardioversion of recent-onset...
A Practical Approach to the Management of Residual Cardiovascular Risk: United Arab Emirates Expert Consensus Panel on the Evidence for Icosapent Ethyl and Omega-3 Fatty Acids
A Practical Approach to the Management of Residual Cardiovascular Risk: United Arab Emirates Expert Consensus Panel on the Evidence for Icosapent Ethyl and Omega-3 Fatty Acids
Patients with hyperlipidemia treated with statins remain at a residual cardiovascular (CV) risk. Omega-3 polyunsaturated f...
Isoimperatorin Inhibits Angiogenesis by Suppressing VEGFR2 Signaling Pathway
Isoimperatorin Inhibits Angiogenesis by Suppressing VEGFR2 Signaling Pathway
Angiogenesis involves in many pathological processes, including tumor metastasis, diabetic retinopathy, and rheumatoid art...
An Integrated Network Pharmacology and RNA-seq Approach for Exploring the Protective Effect of Andrographolide in Doxorubicin-Induced Cardiotoxicity
An Integrated Network Pharmacology and RNA-seq Approach for Exploring the Protective Effect of Andrographolide in Doxorubicin-Induced Cardiotoxicity
Doxorubicin (Dox) is clinically limited due to its dose-dependent cardiotoxicity. Andrographolide (Andro) has been confirm...
Colchicine Attenuates Microvascular Obstruction after Myocardial Ischemia-Reperfusion Injury by Inhibiting the Proliferation of Neutrophil in Bone Marrow
Colchicine Attenuates Microvascular Obstruction after Myocardial Ischemia-Reperfusion Injury by Inhibiting the Proliferation of Neutrophil in Bone Marrow
Complete and rapid recanalization of blood flow by percutaneous coronary intervention (PCI) is the most effective interven...
Beyond Hepatoprotection—The Cardioprotective Effects of Bicyclol in Diabetes
Beyond Hepatoprotection—The Cardioprotective Effects of Bicyclol in Diabetes
Diabetes and obesity are two major risk factors that promote cardiomyopathies such as...
Impact of CYP2C19 Genotype on Efficacy and Safety of Clopidogrel-based Antiplatelet Therapy in Stroke or Transient Ischemic Attack Patients: An Updated Systematic Review and Meta-analysis of Non-East Asian Studies
Impact of CYP2C19 Genotype on Efficacy and Safety of Clopidogrel-based Antiplatelet Therapy in Stroke or Transient Ischemic Attack Patients: An Updated Systematic Review and Meta-analysis of Non-East Asian Studies
Inconclusive and limited results have been reported on the clinical utility of CYP2C19 genotyping in stroke/TIA patients o...
MicroRNA-92a in Cardiovascular Disease: An Insufficiently Explored and Controversial Research Area
MicroRNA-92a in Cardiovascular Disease: An Insufficiently Explored and Controversial Research Area
Wu Q, Wang H, He F, et al. Depletion of microRNA-92a enhances the role of sevoflurane treatment in reducing myocardial isc...
Intervention of Tanshinone IIA on the PGK1-PDHK1 Pathway to Reprogram Macrophage Phenotype After Myocardial Infarction
Intervention of Tanshinone IIA on the PGK1-PDHK1 Pathway to Reprogram Macrophage Phenotype After Myocardial Infarction
Myocardial infarction remains a disease with high morbidity and death rate among cardiovascular diseases. Macrophages are ...
Comparison of Efficacy and Safety Between Drug-Coated Balloons Versus Drug-Eluting Stents in the Treatment of De Novo Coronary Lesions in Large Vessels: A Study-Level Meta-Analysis of Randomized Control Trials
Comparison of Efficacy and Safety Between Drug-Coated Balloons Versus Drug-Eluting Stents in the Treatment of De Novo Coronary Lesions in Large Vessels: A Study-Level Meta-Analysis of Randomized Control Trials
Drug-coated balloons (DCB) can be used as an alternative to drug-eluting stents (DES) in patients with de novo small vesse...
Nicotinamide Riboside Supplementation Restores Myocardial Nicotinamide Adenine Dinucleotide Levels, Improves Survival, and Promotes Protective Environment Post Myocardial Infarction
Nicotinamide Riboside Supplementation Restores Myocardial Nicotinamide Adenine Dinucleotide Levels, Improves Survival, and Promotes Protective Environment Post Myocardial Infarction
Myocardial infarction (MI) is a major cause of death. Nicotinamide adenine dinucleotide (NAD+) is a coenzyme in oxidative ...
Comment on “Comparison of Sodium-Glucose Cotransporter-2 Inhibitor and Dipeptidyl Peptidase-4 Inhibitor on the Risks of New-Onset Atrial Fibrillation, Stroke and Mortality in Diabetic Patients”
Comment on “Comparison of Sodium-Glucose Cotransporter-2 Inhibitor and Dipeptidyl Peptidase-4 Inhibitor on the Risks of New-Onset Atrial Fibrillation, Stroke and Mortality in Diabetic Patients”
Author Contributions Shih-Wei Lai contributed to the conception of ...
Agathis dammara Extract and its Monomer Araucarone Attenuate Abdominal Aortic Aneurysm in Mice
Agathis dammara Extract and its Monomer Araucarone Attenuate Abdominal Aortic Aneurysm in Mice
Abdominal aortic aneurysm (AAA) is a chronic vascular disease wherein the inflammation of vascular smooth muscle cells (VS...
Contemporary Medical Management of Peripheral Arterial Disease
Contemporary Medical Management of Peripheral Arterial Disease
Peripheral arterial disease (PAD) is characterized by atherosclerotic arterial occlusive disease of the lower extremities ...
Possible Cardioprotective Effects of Lactate Infusion After Cardiac Arrest or Prolonged Myocardial Ischemia
Possible Cardioprotective Effects of Lactate Infusion After Cardiac Arrest or Prolonged Myocardial Ischemia
Stevic N, Augaud L, Loufouat J, et al. Molar sodium lactate attenuates the severity of postcardiac arrest syndrome: a prec...
IL-33 Suppresses the Progression of Atherosclerosis via the ERK1/2-IRF1-VCAM-1 Pathway
IL-33 Suppresses the Progression of Atherosclerosis via the ERK1/2-IRF1-VCAM-1 Pathway
This study was designed to explore the effects of interleukin 33 (IL-33) on the progression of atherosclerosis and the pos...
Effects of Dapagliflozin on Myocardial Gene Expression in BTBR Mice with Type 2 Diabetes
Effects of Dapagliflozin on Myocardial Gene Expression in BTBR Mice with Type 2 Diabetes
Dapagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, is approved for the treatment of type 2 diabetes, heart...
Therapeutic Approaches Targeting Ferroptosis in Cardiomyopathy
Therapeutic Approaches Targeting Ferroptosis in Cardiomyopathy
The term cardiomyopathy refers to a group of heart diseases that cause severe heart failure over time. Cardiomyopathies ha...
Pharmacodynamic Drug-Drug Interactions and Bleeding Outcomes in Patients with Atrial Fibrillation Using Non-Vitamin K Antagonist Oral Anticoagulants: a Nationwide Cohort Study
Pharmacodynamic Drug-Drug Interactions and Bleeding Outcomes in Patients with Atrial Fibrillation Using Non-Vitamin K Antagonist Oral Anticoagulants: a Nationwide Cohort Study
Pharmacodynamic drug-drug interactions (PD DDIs) may influence the safety of non-vitamin K antagonist oral anticoagulants ...
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