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ACE Inhibitors and Angiotensin Receptor Blockers for the Primary and Secondary Prevention of Cardiovascular Outcomes: Recommendations from the 2024 Egyptian Cardiology Expert Consensus in Collaboration with the CVREP Foundation
ACE Inhibitors and Angiotensin Receptor Blockers for the Primary and Secondary Prevention of Cardiovascular Outcomes: Recommendations from the 2024 Egyptian Cardiology Expert Consensus in Collaboration with the CVREP Foundation
The renin–angiotensin–aldosterone system (RAAS) plays a pivotal role in regulating blood pressure (BP), with d...
Asia–Pacific Real-World Evolocumab Use, LDL-C Reduction, Physician Goals, and Patient Perceptions: HALES Observational Study
Asia–Pacific Real-World Evolocumab Use, LDL-C Reduction, Physician Goals, and Patient Perceptions: HALES Observational Study
Real-world data are needed to understand the effectiveness of new therapeutic options for low-density lipoprotein choleste...
Sodium Zirconium Cyclosilicate for Renin–Angiotensin–Aldosterone System Inhibitor Optimization in Patients with Heart Failure with Reduced Ejection Fraction: A Retrospective Analysis
Sodium Zirconium Cyclosilicate for Renin–Angiotensin–Aldosterone System Inhibitor Optimization in Patients with Heart Failure with Reduced Ejection Fraction: A Retrospective Analysis
In this retrospective analysis, we evaluate the effectiveness of the potassium (K+) binder sodium zirconium cyclosilicate ...
Predictors and Outcomes of Inappropriate Dosing of Direct Oral Anticoagulants in Patients Receiving Transcatheter Aortic Valve Implantation
Predictors and Outcomes of Inappropriate Dosing of Direct Oral Anticoagulants in Patients Receiving Transcatheter Aortic Valve Implantation
Direct oral anticoagulant (DOAC) dose adjustment is based on age, renal function, and body weight. There is a paucity of d...
Expert Opinion on the Role of Sacubitril/Valsartan in the Management of Hypertension in India
Expert Opinion on the Role of Sacubitril/Valsartan in the Management of Hypertension in India
Hypertension, a key modifiable risk factor for cardiovascular diseases (CVD), significantly contributes to premature death...
Macitentan in Pulmonary Arterial Hypertension Due to Congenital Heart Disease (CHD-PAH): Real-World Evidence from the OPUS/OrPHeUS Studies
Macitentan in Pulmonary Arterial Hypertension Due to Congenital Heart Disease (CHD-PAH): Real-World Evidence from the OPUS/OrPHeUS Studies
Data on real-world clinical practice and outcomes of patients with pulmonary arterial hypertension (PAH) associated with c...
Atrial Fibrillation in Patients with Breast Cancer: A Literature Review
Atrial Fibrillation in Patients with Breast Cancer: A Literature Review
In addition to traditional risk factors, patients with breast cancer are at an increased risk of atrial fibrillation due t...
Impact of Social Determinants of Health on Primary Adherence of Oral Anticoagulants Among Patients with Newly Diagnosed Atrial Fibrillation
Impact of Social Determinants of Health on Primary Adherence of Oral Anticoagulants Among Patients with Newly Diagnosed Atrial Fibrillation
Oral anticoagulants (OAC) reduce the risk of stroke among patients with atrial fibrillation (AF). However, adherence remai...
Prevalence, Patient Characteristics, and Treatment of Patients with Hypertrophic Cardiomyopathy: A Nationwide Payer Database Study
Prevalence, Patient Characteristics, and Treatment of Patients with Hypertrophic Cardiomyopathy: A Nationwide Payer Database Study
Data on the prevalence of hypertrophic cardiomyopathy (HCM), characteristics of patients with HCM, and treatment patterns ...
The Effect of Colchicine on Platelet Function Profiles in Patients with Stable Coronary Artery Disease: The ECLIPSE Pilot Study
The Effect of Colchicine on Platelet Function Profiles in Patients with Stable Coronary Artery Disease: The ECLIPSE Pilot Study
This prospective, single-arm pharmacodynamic study assessed the effect of colchicine (COLC) [Strides Pharma UK Ltd, Watfor...
Cardiovascular Outcomes of Early LDL-C Goal Achievement in Patients with Very-High-Risk ASCVD
Cardiovascular Outcomes of Early LDL-C Goal Achievement in Patients with Very-High-Risk ASCVD
Clinical trial evidence supports early low-density lipoprotein cholesterol (LDL-C) goal achievement in patients with ather...
ACEi and ARBs as Primary Prevention of Cancer Therapy-Related Cardiomyopathy in Patients Undergoing Chemotherapy with Anthracyclines: A Systematic Review and Meta-Analysis
ACEi and ARBs as Primary Prevention of Cancer Therapy-Related Cardiomyopathy in Patients Undergoing Chemotherapy with Anthracyclines: A Systematic Review and Meta-Analysis
Anthracyclines treat a myriad of malignancies; however, they are known to lead to cancer therapy-related cardiomyopathy (C...
Rationale and Design of ANTHOLOGY: An ATTR Amyloidosis Real-World Evidence Program Aiming to Address Gaps in Amyloidosis Care
Rationale and Design of ANTHOLOGY: An ATTR Amyloidosis Real-World Evidence Program Aiming to Address Gaps in Amyloidosis Care
Patients with amyloid transthyretin (ATTR) amyloidosis typically experience rapid disease progression, poor treatment outc...
Impella Versus VA-ECMO for Patients with Cardiogenic Shock: Preliminary Cost-Effectiveness Analysis in the Italian Context
Impella Versus VA-ECMO for Patients with Cardiogenic Shock: Preliminary Cost-Effectiveness Analysis in the Italian Context
Cardiogenic shock (CS) is a life-threatening failure of the heart to supply adequate blood, requiring immediate treatment....
Real-World Effectiveness of High-Dose Tafamidis on Neurologic Disease Progression in Mixed-Phenotype Variant Transthyretin Amyloid Cardiomyopathy
Real-World Effectiveness of High-Dose Tafamidis on Neurologic Disease Progression in Mixed-Phenotype Variant Transthyretin Amyloid Cardiomyopathy
Transthyretin amyloidosis (ATTR) is a progressive, heterogeneous rare disease manifesting as ATTR polyneuropathy (ATTR-PN)...
Derivation of Stroke Volume from Pulmonary Artery Pressures
Derivation of Stroke Volume from Pulmonary Artery Pressures
Intermittent cardiac output (CO) studies using thermodilution are considered the gold standard. We have developed a stroke...
Tafamidis 61 mg Patient Characteristics and Persistency? A Retrospective Analysis of German Statutory Health Insurance Data (IQVIA™ LRx)
Tafamidis 61 mg Patient Characteristics and Persistency? A Retrospective Analysis of German Statutory Health Insurance Data (IQVIA™ LRx)
Tafamidis is the first drug approved by the European Commission for the treatment of wild-type or hereditary transthyretin...
Broadening Perspectives of Artificial Intelligence in Echocardiography
Broadening Perspectives of Artificial Intelligence in Echocardiography
Echocardiography frequently serves as the first-line treatment of diagnostic imaging for several pathological entities in ...
Milvexian: An Oral, Bioavailable Factor XIa Inhibitor
Milvexian: An Oral, Bioavailable Factor XIa Inhibitor
Direct oral anticoagulants have a dose-dependent increased bleeding risk which limits use in certain populations. Studies ...
Safety and Effectiveness of Four-Factor Prothrombin Complex Concentrate in Special Populations with INR Below 2: A Post-Marketing Surveillance Study
Safety and Effectiveness of Four-Factor Prothrombin Complex Concentrate in Special Populations with INR Below 2: A Post-Marketing Surveillance Study
We previously conducted a prospective, observational post-marketing surveillance study to assess the safety and effectiven...
Prevalence of Tendon Rupture and Tendinopathies Among Patients with Atherosclerotic Cardiovascular Disease Derived From United States Administrative Claims Data
Prevalence of Tendon Rupture and Tendinopathies Among Patients with Atherosclerotic Cardiovascular Disease Derived From United States Administrative Claims Data
The prevalence of tendon rupture and tendinopathies (TRT) has not been determined in a large population of patients with a...
Narrative Review: Surgical and Hybrid Management of Atrial Fibrillation
Narrative Review: Surgical and Hybrid Management of Atrial Fibrillation
Although significant strides have been made in non-pharmacologic management of atrial fibrillation (AF), these treatments ...
Prognostic Implications of Coronary Artery Sclerosis in Troponin-Positive Patients with Non-Obstructive Coronary Arteries
Prognostic Implications of Coronary Artery Sclerosis in Troponin-Positive Patients with Non-Obstructive Coronary Arteries
Coronary sclerosis is a risk factor for the progression to obstructive coronary artery disease (CAD). However, understandi...
Implementing a Quality Intervention to Improve Confidence in Outpatient Venous Thromboembolism Management
Implementing a Quality Intervention to Improve Confidence in Outpatient Venous Thromboembolism Management
Guidelines recommend that patients with acute venous thromboembolism (VTE) represented by low-risk deep vein thrombosis (D...
All-Cause Mortality of Atrial Fibrillation and Heart Failure in the Same Patient: Does the Order Matter?
All-Cause Mortality of Atrial Fibrillation and Heart Failure in the Same Patient: Does the Order Matter?
Atrial fibrillation (AF) and heart failure (HF) often coexist due to the common elements of the pathomechanism they share....
Pharmacodynamic Comparison of Two Aspirin Formulations in the Caribbean: The ARC Study
Pharmacodynamic Comparison of Two Aspirin Formulations in the Caribbean: The ARC Study
This prospective, single-arm, crossover pharmacodynamic study assessed the effect of Bayer® low-dose enteric-coated a...
Ten-year Durability, Hemodynamic Performance, and Clinical Outcomes after Transcatheter Aortic Valve Implantation Using a Self-expanding Device
Ten-year Durability, Hemodynamic Performance, and Clinical Outcomes after Transcatheter Aortic Valve Implantation Using a Self-expanding Device
The expansion of transcatheter aortic valve implantation (TAVI) to low-risk and younger patients has increased the relevan...
Recent Advances in Targeted Management of Inflammation In Atherosclerosis: A Narrative Review
Recent Advances in Targeted Management of Inflammation In Atherosclerosis: A Narrative Review
Atherosclerotic cardiovascular disease (ASCVD) remains a leading cause of morbidity and mortality despite effective low-de...
National Trends in Aspirin Use and Expenditures in the United States: Analysis of The Medical Expenditure Panel Survey 2000–2021
National Trends in Aspirin Use and Expenditures in the United States: Analysis of The Medical Expenditure Panel Survey 2000–2021
Since its invention in 1897, aspirin (ASA) has been the most widely used and cost-effective antiplatelet agent to prevent ...
Clinical and Genotype Characteristics and Symptom Migration in Patients With Mixed Phenotype Transthyretin Amyloidosis from the Transthyretin Amyloidosis Outcomes Survey
Clinical and Genotype Characteristics and Symptom Migration in Patients With Mixed Phenotype Transthyretin Amyloidosis from the Transthyretin Amyloidosis Outcomes Survey
Transthyretin amyloidosis (ATTR amyloidosis) is primarily associated with a cardiac or neurologic phenotype, but a mixed p...
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