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Gene expression profiling in elderly patients with familial hypercholesterolemia with and without coronary heart disease
Gene expression profiling in elderly patients with familial hypercholesterolemia with and without coronary heart disease
Background and aimsElderly familial hypercholesterolemia (FH) patients are at high risk of coronary heart disease (CHD) du...
Insulin resistance is an important index to assess glucose and insulin metabolism, but not a biological risk factor for high-risk coronary artery plaque composition
Insulin resistance is an important index to assess glucose and insulin metabolism, but not a biological risk factor for high-risk coronary artery plaque composition
Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2024 Elsevier B.V., its licensors, an...
Reply to: “Insulin resistance is an important index to assess glucose and insulin metabolism, but not a biological risk factor for high-risk coronary artery plaque composition”
Reply to: “Insulin resistance is an important index to assess glucose and insulin metabolism, but not a biological risk factor for high-risk coronary artery plaque composition”
Cookies are used by this site. Cookie SettingsAll content on this site: Copyright © 2024 Elsevier B.V., its licensors, an...
Longitudinal albuminuria patterns predict coronary artery calcification progression: Findings from the coronary artery risk development in young adults study
Longitudinal albuminuria patterns predict coronary artery calcification progression: Findings from the coronary artery risk development in young adults study
Albuminuria, an early biomarker of kindey dysfuction, has been associated with an increased risk of adverse cardiovascular...
A novel protein encoded by circLARP1B promotes the proliferation and migration of vascular smooth muscle cells by suppressing cAMP signaling
A novel protein encoded by circLARP1B promotes the proliferation and migration of vascular smooth muscle cells by suppressing cAMP signaling
The most prevalent vascular disease, atherosclerosis (AS), has a significant role in cerebral infarction, stroke, and cere...
Induction of Let-7d-5p miRNA modulates aortic smooth muscle inflammatory signaling and phenotypic switching.
Induction of Let-7d-5p miRNA modulates aortic smooth muscle inflammatory signaling and phenotypic switching.
Background and aimsActivation of vascular smooth muscle cell inflammation is recognised as an important early driver of va...
Long-term ambient air pollution and coronary atherosclerosis: Results from the Swedish SCAPIS study
Long-term ambient air pollution and coronary atherosclerosis: Results from the Swedish SCAPIS study
Available online 8 May 2024, 117576Author links open overlay panel, , , , , , , , , , , , , , , , , , Highlights•Firm evid...
Lifestyle factors as determinants of atherosclerotic cardiovascular health
Lifestyle factors as determinants of atherosclerotic cardiovascular health
A sedentary lifestyle, low levels of physical activity and fitness, poor dietary patterns, and psychosocial stress are str...
Liver-specific Lxr inhibition represses reverse cholesterol transport in cholesterol-fed mice
Liver-specific Lxr inhibition represses reverse cholesterol transport in cholesterol-fed mice
Low plasma levels of HDL-cholesterol (HDL-C) have been consistently associated with increased risk of atherosclerotic card...
Advancements in risk stratification and management strategies in primary cardiovascular prevention
Advancements in risk stratification and management strategies in primary cardiovascular prevention
While there have been notable advancements in the management of atherosclerotic cardiovascular disease (ASCVD), a crucial ...
Relationship of Apolipoprotein C-III proteoform composition with ankle-brachial index and peripheral artery disease in the Multi-Ethnic Study of Atherosclerosis (MESA)
Relationship of Apolipoprotein C-III proteoform composition with ankle-brachial index and peripheral artery disease in the Multi-Ethnic Study of Atherosclerosis (MESA)
Keywordsapolipoproteinslipidsposttranslational proteoformsankle-brachial indexperipheral artery diseaseAbbreviationsapoC-I...
The LEPIS-HuR-TMOD4 axis regulates hepatic cholesterol homeostasis and accelerates atherosclerosis
The LEPIS-HuR-TMOD4 axis regulates hepatic cholesterol homeostasis and accelerates atherosclerosis
Cardiovascular disease (CVD) is the most important chronic noncommunicable disease threatening human life and health world...
Impact of loss-of-function in angiopoietin-like 4 on the human phenome
Impact of loss-of-function in angiopoietin-like 4 on the human phenome
Volume 393, June 2024, 117558Author links open overlay panel, , , , Highlights•E40K is the most common loss-of-function va...
Outcomes of management strategies in patients with prior coronary artery bypass grafting presenting with an acute coronary syndrome
Outcomes of management strategies in patients with prior coronary artery bypass grafting presenting with an acute coronary syndrome
MethodsUsing linked administrative databases, we examined patients with an ACS between 2008 and 2019, identifying patients...
Differential age-specific associations of LDL cholesterol and body mass index with coronary heart disease
Differential age-specific associations of LDL cholesterol and body mass index with coronary heart disease
Population aging leads to an increased incidence of coronary heart disease (CHD). Low‐density lipoprotein cholesterol (LDL...
Insulin resistance in the adipose tissue predicts future vascular resistance: The Hiroshima Study on Glucose Metabolism and Cardiovascular Diseases
Insulin resistance in the adipose tissue predicts future vascular resistance: The Hiroshima Study on Glucose Metabolism and Cardiovascular Diseases
Insulin resistance refers to reduced insulin response in the target tissues, including liver, skeletal muscle, and adipose...
Enhanced identification of familial hypercholesterolemia using central laboratory algorithms
Enhanced identification of familial hypercholesterolemia using central laboratory algorithms
Background and aimsFamilial hypercholesterolemia (FH) is a highly prevalent genetic disorder resulting in markedly elevate...
Treatment patterns and adherence to lipid-lowering drugs during eight-year follow-up after a coronary heart disease event
Treatment patterns and adherence to lipid-lowering drugs during eight-year follow-up after a coronary heart disease event
Volume 393, June 2024, 117550Author links open overlay panel, , , , , , , Highlights•Less than 70 % of patients with coron...
An evaluation of the cost-effectiveness of population genetic screening for familial hypercholesterolemia in US patients
An evaluation of the cost-effectiveness of population genetic screening for familial hypercholesterolemia in US patients
In the United States, approximately 1 in every 212 people are affected by familial hypercholesterolemia (FH), a hereditary...
Remnant cholesterol, LDL cholesterol, and apoB absolute mass changes explain results of the PROMINENT trial
Remnant cholesterol, LDL cholesterol, and apoB absolute mass changes explain results of the PROMINENT trial
Background and aimsThe PROMINENT trial, a cardiovascular outcome trial of the triglyceride- and remnant cholesterol-loweri...
Plasma levels of PRO-C3, a type III collagen synthesis marker, are associated with arterial stiffness and increased risk of cardiovascular death
Plasma levels of PRO-C3, a type III collagen synthesis marker, are associated with arterial stiffness and increased risk of cardiovascular death
Available online 10 December 2023, 117420Author links open overlay panel, , , , , , , , , Highlights•N-terminal propeptide...
Coronary artery calcium screening: He who buys what he does not need steals from himself
Coronary artery calcium screening: He who buys what he does not need steals from himself
Available online 10 December 2023, 117411Author links open overlay panel, , Section snippetsDeclaration of interestsThe au...
Comments on “Higher exercise capacity, but not omega-3 fatty acid consumption, predicts lower coronary artery calcium scores in women and men with coronary artery disease”
Comments on “Higher exercise capacity, but not omega-3 fatty acid consumption, predicts lower coronary artery calcium scores in women and men with coronary artery disease”
Available online 10 December 2023, 117426Author links open overlay panel, Section snippetsThe lowest p-value doesn't guara...
The association of lipoprotein (a) with coronary artery calcification: A systematic review and meta-analysis
The association of lipoprotein (a) with coronary artery calcification: A systematic review and meta-analysis
Coronary artery disease (CAD) is a critical cardiovascular disease (CVD) and the leading cause of death worldwide [1]. Ath...
Timing of clinic visits after health checks and risk of hospitalization for cardiovascular events and all-cause death among the high-risk population
Timing of clinic visits after health checks and risk of hospitalization for cardiovascular events and all-cause death among the high-risk population
Health checks have been long considered effective in the primary prevention of chronic diseases; a number of observational...
Parental cardiovascular disease and cardiovascular disease risk factors in the offspring: The diet, cancer and health cohorts
Parental cardiovascular disease and cardiovascular disease risk factors in the offspring: The diet, cancer and health cohorts
Cardiovascular disease (CVD) accounts for almost 33% of all deaths and 388 million disability-adjusted life years globally...
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K.K. TeoTobacco use and risk of myocardial infarction in 52 countries in the INTERHEART study: a case-control studyLancet(...
Monocyte transcriptomic profile following EPA and DHA supplementation in men and women with low-grade chronic inflammation
Monocyte transcriptomic profile following EPA and DHA supplementation in men and women with low-grade chronic inflammation
Chronic low-grade inflammation is a major factor in all stages of cardiovascular disease (CVD), from initiation to progres...
From puzzle pieces to picture: Genetic data helps refine our understanding of the link between liver fat and heart disease risk
From puzzle pieces to picture: Genetic data helps refine our understanding of the link between liver fat and heart disease risk
Available online 3 December 2023, 117410Author links open overlay panel, Section snippetsFinancial supportThis work was fu...
The relationship between genetic liver fat and coronary heart disease is explained by apoB-containing lipoproteins
The relationship between genetic liver fat and coronary heart disease is explained by apoB-containing lipoproteins
Background and aimsThe relationship between genetically-driven liver fat and coronary heart disease (CHD) remains unclear....
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