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New interest in fibrinogen as an ischemic risk factor
New interest in fibrinogen as an ischemic risk factor
Platelet-fibrin clot formation is a key process in acute arterial thrombosis. The relationship between thrombin-induced pl...
Enhanced thrombin generation induced by extracellular vesicles from severe COVID−19 cases
Enhanced thrombin generation induced by extracellular vesicles from severe COVID−19 cases
Authors and AffiliationsUniversity of Sao Paulo Medical School, Sao Paulo, BrazilBárbara Gomes Barion & Thaís Dourado ...
The use of non-vitamin K antagonist oral anticoagulants in chronic thromboembolic pulmonary hypertension: an updated meta-analysis
The use of non-vitamin K antagonist oral anticoagulants in chronic thromboembolic pulmonary hypertension: an updated meta-analysis
Studies have demonstrated the beneficial effects of non-vitamin K antagonist oral anticoagulants (NOACs) for the treatment...
Bleeding outcomes in critically ill patients on heparin with discordant aPTT and anti-Xa activity
Bleeding outcomes in critically ill patients on heparin with discordant aPTT and anti-Xa activity
• Hospitalized patients may exhibit discordance in aPTT and anti-Xa activities while on UFH. • In this study, ...
ASTRAL scale for predicting prognosis following intravenous thrombolysis with anterior versus posterior circulation acute ischemic stroke
ASTRAL scale for predicting prognosis following intravenous thrombolysis with anterior versus posterior circulation acute ischemic stroke
In this study, we compared whether there was any difference between the ASTRAL(Acute Stroke Registry and Analysis of Lausa...
The protective effects of annexin A1 against oxidized-LDL-induced monocytes adhesion to endothelial cells: implication in atherosclerosis
The protective effects of annexin A1 against oxidized-LDL-induced monocytes adhesion to endothelial cells: implication in atherosclerosis
Oxidized low-density lipoprotein (ox-LDL)-associated endothelial dysfunction is a critical factor in the initiation and pr...
Development of the Pulmonary Embolism Progression (PEP) score for predicting short-term clinical deterioration in intermediate-risk pulmonary embolism: a single-center retrospective study
Development of the Pulmonary Embolism Progression (PEP) score for predicting short-term clinical deterioration in intermediate-risk pulmonary embolism: a single-center retrospective study
Accurate risk stratification in acute intermediate-risk pulmonary embolism (PE) is essential. Current prediction scores la...
Discovery of a new lead molecule to develop a novel class of human factor XIIa inhibitors
Discovery of a new lead molecule to develop a novel class of human factor XIIa inhibitors
Factor XIIa (FXIIa) is a plasma serine protease within the contact activation pathway. Inhibiting FXIIa could offer a viab...
Optimal intravenous antiplatelet therapy in patients with ST-elevation myocardial infarction: is the picture becoming clearer?
Optimal intravenous antiplatelet therapy in patients with ST-elevation myocardial infarction: is the picture becoming clearer?
In patients with ST-elevation myocardial infarction (STEMI) undergoing percutaneous c...
Equivalent thrombotic risk with Warfarin, Dabigatran, or Enoxaparin after failure of initial direct oral anticoagulation (DOAC) therapy
Equivalent thrombotic risk with Warfarin, Dabigatran, or Enoxaparin after failure of initial direct oral anticoagulation (DOAC) therapy
The direct oral anticoagulants (DOACs) are now commonly regarded as first line anticoagulants in most cases of venous thro...
Impaired fibrinolysis in patients with atrial fibrillation and elevated circulating lipopolysaccharide
Impaired fibrinolysis in patients with atrial fibrillation and elevated circulating lipopolysaccharide
It is unknown whether elevated gut-derived serum lipopolysaccharide (LPS) can affect thrombin generation, fibrinolysis, an...
Haemostatic gene variations in cervical cancer-associated venous thrombosis: considerations for clinical strategies
Haemostatic gene variations in cervical cancer-associated venous thrombosis: considerations for clinical strategies
Venous thromboembolism (VTE) is a life-threatening haemostatic disease frequently diagnosed among the cancer population. T...
Cerebral venous sinus thrombosis associated with cancer: analysis of the ACTION-CVT study
Cerebral venous sinus thrombosis associated with cancer: analysis of the ACTION-CVT study
Nearly one fifth of patients with venous thromboembolism (VTE) have cancer. When both of these conditions occur, especiall...
ET1 acts as a potential plasma biomarker and therapeutic target in deep venous thrombosis rat model
ET1 acts as a potential plasma biomarker and therapeutic target in deep venous thrombosis rat model
Deep venous thrombosis (DVT) is the third leading cause of death in cardiovascular disease, following heart attacks and st...
Effect of Ultrasound on Thrombus debris during Sonothrombolysis in a Microfluidic device
Effect of Ultrasound on Thrombus debris during Sonothrombolysis in a Microfluidic device
Microbubble-mediated sonothrombolysis has been proven to be a non-invasive and efficient method for thrombolysis. Neverthe...
Assessment of associations between neutrophil extracellular trap biomarkers in blood and thrombi in acute ischemic stroke patients
Assessment of associations between neutrophil extracellular trap biomarkers in blood and thrombi in acute ischemic stroke patients
Inflammation including immunothrombosis by neutrophil extracellular traps (NETs) has important implications in acute ische...
Elevated plasma protein carbonylation increases the risk of ischemic cerebrovascular events in patients with atrial fibrillation: association with a prothrombotic state
Elevated plasma protein carbonylation increases the risk of ischemic cerebrovascular events in patients with atrial fibrillation: association with a prothrombotic state
Plasma protein carbonylation that reflects oxidative stress has been demonstrated to be associated with the prothrombotic ...
The journal of thrombosis and thrombolysis: commemorating the written word in science and medicine: three decades and counting
The journal of thrombosis and thrombolysis: commemorating the written word in science and medicine: three decades and counting
1st decadeThe 1990s and the beginning of the 21st century was a time for understanding the mechanisms and pathophysiology ...
SARS-CoV-2 spike protein potentiates platelet aggregation via upregulating integrin αIIbβ3 outside-in signaling pathway
SARS-CoV-2 spike protein potentiates platelet aggregation via upregulating integrin αIIbβ3 outside-in signaling pathway
Platelet hyperreactivity is one of the crucial causes of coagulative disorders in patients with COVID-19. Few studies have...
Reduced protein carbonylation on hormone therapy is associated with improved fibrinolysis in postmenopausal women: the impact of PAI-1 and TAFI activity
Reduced protein carbonylation on hormone therapy is associated with improved fibrinolysis in postmenopausal women: the impact of PAI-1 and TAFI activity
Hormone therapy (HT) has been reported to reduce protein carbonylation (PC) in postmenopausal women, in whom fibrinolysis ...
Initial hemodynamic status and Acute Mortality in Cancer patients with Acute Pulmonary Embolism: from the COMMAND VTE Registry
Initial hemodynamic status and Acute Mortality in Cancer patients with Acute Pulmonary Embolism: from the COMMAND VTE Registry
Initial hemodynamic status in patients with acute pulmonary embolism (PE) concerns their acute clinical outcomes. Neverthe...
Risk of venous thromboembolism in relation to high physical activity level in men over 27 year follow up
Risk of venous thromboembolism in relation to high physical activity level in men over 27 year follow up
Venous thromboembolism (VTE) is the third most common type of cardiovascular disease. An association between high level of...
Clinical outcomes of patients with atrial fibrillation in relation to multimorbidity status changes over time and the impact of ABC pathway compliance: a nationwide cohort study
Clinical outcomes of patients with atrial fibrillation in relation to multimorbidity status changes over time and the impact of ABC pathway compliance: a nationwide cohort study
Patients with atrial fibrillation (AF) commonly have associated comorbidities. The primary aim was to determine the effect...
Accuracy of the COMPASS-CAT thrombosis risk assessment scale in predicting venous thromboembolism in cancer patients: a meta-analysis
Accuracy of the COMPASS-CAT thrombosis risk assessment scale in predicting venous thromboembolism in cancer patients: a meta-analysis
This systematic review aims to assess the accuracy of the COMPASS-CAT tool in predicting venous thromboembolism (VTE) amon...
Remote intensive management to improve antiplatelet adherence in acute myocardial infarction: a secondary analysis of the randomized controlled IMMACULATE trial
Remote intensive management to improve antiplatelet adherence in acute myocardial infarction: a secondary analysis of the randomized controlled IMMACULATE trial
This study aim to investigate if remote intensive coaching for the first 6 months post-AMI will improve adherence to the t...
Anticoagulant prescribing patterns in patients with primary central nervous system malignancies and secondary metastases
Anticoagulant prescribing patterns in patients with primary central nervous system malignancies and secondary metastases
To evaluate the safety of direct oral anticoagulants (DOACs) versus low-molecular weight heparin (LMWH) in patients with c...
Outcomes of mechanical thrombectomy in acute stroke patients with atrial fibrillation detected after stroke versus known atrial fibrillation
Outcomes of mechanical thrombectomy in acute stroke patients with atrial fibrillation detected after stroke versus known atrial fibrillation
We aim to compare the outcomes in patients with atrial fibrillation detected after stroke (AFDAS) and their counterparts w...
Efficacy and safety of rivaroxaban versus apixaban for venous thromboembolism: A systematic review and meta-analysis of observational studies
Efficacy and safety of rivaroxaban versus apixaban for venous thromboembolism: A systematic review and meta-analysis of observational studies
Direct-acting oral anticoagulants (DOACs) including rivaroxaban and apixaban are preferred over vitamin K antagonists for ...
Direct oral anticoagulants versus vitamin K antagonists in patients with atrial fibrillation and stage 5 chronic kidney disease under dialysis: A systematic review and meta-analysis of randomized controlled trials
Direct oral anticoagulants versus vitamin K antagonists in patients with atrial fibrillation and stage 5 chronic kidney disease under dialysis: A systematic review and meta-analysis of randomized controlled trials
In patients with atrial fibrillation (AF) and normal or slightly impaired renal function, the use of direct oral anticoagu...
Adherence to direct or vitamin K antagonist oral anticoagulants in patients with atrial fibrillation: a long-term observational study
Adherence to direct or vitamin K antagonist oral anticoagulants in patients with atrial fibrillation: a long-term observational study
Our objectives were to measure long-term adherence to oral anticoagulants (OACs) in patients with atrial fibrillation (AF)...
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