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Presence of microplastics in carotid plaques linked to cardiovascular events
In patients with carotid artery disease, the presence of microplastics and nanoplastics in the carotid plaque is associate...
Long-read sequencing provides insights into genetic influence
Long-read sequencing provides insights into genetic influence
In this Tools of the Trade article, Trivett discusses the potential of long-read sequencing in generating high-quality ref...
Protein glycosylation in cardiovascular health and disease
Protein glycosylation in cardiovascular health and disease
Protein glycosylation, which involves the attachment of carbohydrates to proteins, is one of the most abundant protein co-...
Non-coding RNAs as therapeutic targets and biomarkers in ischaemic heart disease
Non-coding RNAs as therapeutic targets and biomarkers in ischaemic heart disease
The adult heart is a complex, multicellular organ that is subjected to a series of regulatory stimuli and circuits and has...
Optimizing antithrombotic therapy in patients with coexisting cardiovascular and gastrointestinal disease
Optimizing antithrombotic therapy in patients with coexisting cardiovascular and gastrointestinal disease
Balancing the safety and efficacy of antithrombotic agents in patients with gastrointestinal disorders is challenging beca...
Author Correction: 2023 World Heart Federation guidelines for the echocardiographic diagnosis of rheumatic heart disease
Division of Adult Cardiology, Uganda Heart Institute, Kampala, UgandaJoselyn Rwebembera & Emmy OkelloGlobal and Tropic...
Contemporary pharmacological treatment and management of heart failure
Contemporary pharmacological treatment and management of heart failure
The prevention and treatment strategies for heart failure (HF) have evolved in the past two decades. The stages of HF have...
A newly identified gut hormone suppresses cholesterol production in the liver
A new study identifies a hormone that is secreted by the gut in response to cholesterol absorption and can inhibit cholest...
Clonal expansion of CD8+ T cells in aged mice linked to pro-atherogenic phenotype
In aged mice, but not young mice, with atherosclerosis, depletion of CD8+ T cells significantly reduces atherosclerotic le...
Levothyroxine supplementation does not improve heart transplantation from brain-dead donors
The use of intravenous levothyroxine does not increase the likelihood of hearts being transplanted from haemodynamically u...
Mosaic loss of chromosome Y and cardiovascular disease
Mosaic loss of chromosome Y and cardiovascular disease
Mosaic loss of chromosome Y (mLOY) refers to the condition in male individuals in which a detectable fraction of cells los...
Anticoagulation in patients with atrial high-rate episodes
Anticoagulation in patients with atrial high-rate episodes
The risk of stroke in patients with atrial high-rate episodes (AHREs) depends on age, comorbidities and AHRE burden. Two r...
Not a spectator sport: improving participation of Black patients in cardiovascular clinical trials
Representation of Black patients in cardiovascular clinical trials remains dismally low, reflective of systemic and struct...
Author Correction: Coronary microvascular obstruction and dysfunction in patients with acute myocardial infarction
Department of Cardiology, Maria Cecilia Hospital, GVM Care & Research, Cotignola, ItalyMattia GalliDepartment of Cardi...
Base editing therapy corrects long QT syndrome in mice
Gene therapy involving adenine base editing can correct a pathogenic variant in the Scn5a gene and alleviate arrhythmia ph...
The case for eliminating racial and ethnic cardiovascular disparities in the USA
Racial and ethnic disparities in cardiovascular health in the USA result in a persistent mortality gap between white and B...
PCI for stable angina
PCI for stable angina
In the ORBITA-2 trial, percutaneous coronary intervention was associated with a lower angina symptom score compared with a...
Non-invasive ultrasound therapy for calcified aortic valve stenosis
In patients with severe calcified aortic valve stenosis, treatment with transthoracically delivered non-invasive ultrasoun...
MINT trial signals potential benefit of liberal transfusion strategy in MI with anaemia
A liberal strategy of blood transfusion might improve outcomes in patients with acute myocardial infarction and anaemia, a...
SELECT shows cardiovascular risk reduction with weight-loss drug semaglutide in people without diabetes
SELECT shows cardiovascular risk reduction with weight-loss drug semaglutide in people without diabetes
Treatment with the glucagon-like peptide 1 receptor agonist semaglutide, administered subcutaneously at a dose of 2.4̴...
New insights into dietary cholesterol absorption
New insights into dietary cholesterol absorption
Aster proteins are involved in the non-vesicular transport of cholesterol derived from dietary lipids in the small intesti...
Self-monitoring strategy reduces postpartum hypertension and cardiac remodelling
In women with elevated levels of blood pressure during pregnancy, the use of a physician-guided remote telemonitoring prog...
Coronary microvascular obstruction and dysfunction in patients with acute myocardial infarction
Coronary microvascular obstruction and dysfunction in patients with acute myocardial infarction
Despite prompt epicardial recanalization in patients presenting with ST-segment elevation myocardial infarction (STEMI), c...
Aspirin exclusion in patients with an LVAD
Data from the ARIES-HM3 trial show that excluding aspirin from the antithrombotic regimen in patients with advanced heart ...
Long non-coding RNAs in cardiac hypertrophy and heart failure: functions, mechanisms and clinical prospects
Long non-coding RNAs in cardiac hypertrophy and heart failure: functions, mechanisms and clinical prospects
The surge in reports describing non-coding RNAs (ncRNAs) has focused attention on their possible biological roles and effe...
Long-term outcomes and device failure after TAVI
Long-term outcomes and device failure after TAVI
Transcatheter aortic valve implantation (TAVI) has become an important treatment option for aortic stenosis, even among yo...
The role of the NLRP3 inflammasome and pyroptosis in cardiovascular diseases
The role of the NLRP3 inflammasome and pyroptosis in cardiovascular diseases
An intense, stereotyped inflammatory response occurs in response to ischaemic and non-ischaemic injury to the myocardium. ...
Patisiran is beneficial for the treatment of TTR cardiac amyloidosis
Patisiran is beneficial for the treatment of TTR cardiac amyloidosis
Treatment with the small interfering RNA patisiran preserves functional capacity and improves health status and quality of...
Drug-eluting resorbable scaffolds are superior to angioplasty for infrapopliteal artery disease
Drug-eluting resorbable scaffolds are superior to angioplasty for infrapopliteal artery disease
In the LIFE-BTK trial, treatment with an everolimus-eluting resorbable scaffold was superior to angioplasty in improving c...
Lipoprotein(a), platelet function and cardiovascular disease
Lipoprotein(a), platelet function and cardiovascular disease
Lipoprotein(a) (Lp(a)) is associated with atherothrombosis through several mechanisms, including putative antifibrinolytic...
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