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Dietary patterns to promote cardiometabolic health
Dietary patterns to promote cardiometabolic health
Multiple professional societies recommend the Mediterranean and/or Dietary Approaches to Stop Hypertension dietary pattern...
Functional control of myosin motors in the cardiac cycle
Functional control of myosin motors in the cardiac cycle
Contraction of the heart is driven by cyclical interactions between myosin and actin filaments powered by ATP hydrolysis. ...
Computational modelling of cardiovascular pathophysiology to risk stratify commercial spaceflight
Computational modelling of cardiovascular pathophysiology to risk stratify commercial spaceflight
For more than 60 years, humans have travelled into space. Until now, the majority of astronauts have been professional, go...
Cardiac sarcomere turnover by unidirectional replacement of proteins
Cardiac sarcomere turnover by unidirectional replacement of proteins
A new study indicates that proteins in the sarcomere complex are stochastically removed and degraded and are replaced by n...
Standardization and clinical applications of retinal imaging biomarkers for cardiovascular disease: a Roadmap from an NHLBI workshop
Standardization and clinical applications of retinal imaging biomarkers for cardiovascular disease: a Roadmap from an NHLBI workshop
The accessibility of the retina with the use of non-invasive and relatively low-cost ophthalmic imaging techniques and ana...
Reactive oxygen species in hypertension
Reactive oxygen species in hypertension
Hypertension is a leading risk factor for stroke, heart disease and chronic kidney disease. Multiple interacting factors a...
Epidemiology of cardiometabolic health in Latin America and strategies to address disparities
Epidemiology of cardiometabolic health in Latin America and strategies to address disparities
In Latin America and the Caribbean (LAC), sociodemographic context, socioeconomic disparities and the high level of urbani...
Potential new therapeutic target for HFpEF
Potential new therapeutic target for HFpEF
A new small-molecule inhibitor of vasohibins reduces myocardial stiffness and improves diastolic relaxation in a rat model...
Presence of microplastics in carotid plaques linked to cardiovascular events
In patients with carotid artery disease, the presence of microplastics and nanoplastics in the carotid plaque is associate...
Long-read sequencing provides insights into genetic influence
Long-read sequencing provides insights into genetic influence
In this Tools of the Trade article, Trivett discusses the potential of long-read sequencing in generating high-quality ref...
Protein glycosylation in cardiovascular health and disease
Protein glycosylation in cardiovascular health and disease
Protein glycosylation, which involves the attachment of carbohydrates to proteins, is one of the most abundant protein co-...
Non-coding RNAs as therapeutic targets and biomarkers in ischaemic heart disease
Non-coding RNAs as therapeutic targets and biomarkers in ischaemic heart disease
The adult heart is a complex, multicellular organ that is subjected to a series of regulatory stimuli and circuits and has...
Optimizing antithrombotic therapy in patients with coexisting cardiovascular and gastrointestinal disease
Optimizing antithrombotic therapy in patients with coexisting cardiovascular and gastrointestinal disease
Balancing the safety and efficacy of antithrombotic agents in patients with gastrointestinal disorders is challenging beca...
Author Correction: 2023 World Heart Federation guidelines for the echocardiographic diagnosis of rheumatic heart disease
Division of Adult Cardiology, Uganda Heart Institute, Kampala, UgandaJoselyn Rwebembera & Emmy OkelloGlobal and Tropic...
Contemporary pharmacological treatment and management of heart failure
Contemporary pharmacological treatment and management of heart failure
The prevention and treatment strategies for heart failure (HF) have evolved in the past two decades. The stages of HF have...
A newly identified gut hormone suppresses cholesterol production in the liver
A new study identifies a hormone that is secreted by the gut in response to cholesterol absorption and can inhibit cholest...
Clonal expansion of CD8+ T cells in aged mice linked to pro-atherogenic phenotype
In aged mice, but not young mice, with atherosclerosis, depletion of CD8+ T cells significantly reduces atherosclerotic le...
Levothyroxine supplementation does not improve heart transplantation from brain-dead donors
The use of intravenous levothyroxine does not increase the likelihood of hearts being transplanted from haemodynamically u...
Mosaic loss of chromosome Y and cardiovascular disease
Mosaic loss of chromosome Y and cardiovascular disease
Mosaic loss of chromosome Y (mLOY) refers to the condition in male individuals in which a detectable fraction of cells los...
Anticoagulation in patients with atrial high-rate episodes
Anticoagulation in patients with atrial high-rate episodes
The risk of stroke in patients with atrial high-rate episodes (AHREs) depends on age, comorbidities and AHRE burden. Two r...
Not a spectator sport: improving participation of Black patients in cardiovascular clinical trials
Representation of Black patients in cardiovascular clinical trials remains dismally low, reflective of systemic and struct...
Author Correction: Coronary microvascular obstruction and dysfunction in patients with acute myocardial infarction
Department of Cardiology, Maria Cecilia Hospital, GVM Care & Research, Cotignola, ItalyMattia GalliDepartment of Cardi...
Base editing therapy corrects long QT syndrome in mice
Gene therapy involving adenine base editing can correct a pathogenic variant in the Scn5a gene and alleviate arrhythmia ph...
The case for eliminating racial and ethnic cardiovascular disparities in the USA
Racial and ethnic disparities in cardiovascular health in the USA result in a persistent mortality gap between white and B...
PCI for stable angina
PCI for stable angina
In the ORBITA-2 trial, percutaneous coronary intervention was associated with a lower angina symptom score compared with a...
Non-invasive ultrasound therapy for calcified aortic valve stenosis
In patients with severe calcified aortic valve stenosis, treatment with transthoracically delivered non-invasive ultrasoun...
MINT trial signals potential benefit of liberal transfusion strategy in MI with anaemia
A liberal strategy of blood transfusion might improve outcomes in patients with acute myocardial infarction and anaemia, a...
SELECT shows cardiovascular risk reduction with weight-loss drug semaglutide in people without diabetes
SELECT shows cardiovascular risk reduction with weight-loss drug semaglutide in people without diabetes
Treatment with the glucagon-like peptide 1 receptor agonist semaglutide, administered subcutaneously at a dose of 2.4̴...
New insights into dietary cholesterol absorption
New insights into dietary cholesterol absorption
Aster proteins are involved in the non-vesicular transport of cholesterol derived from dietary lipids in the small intesti...
Self-monitoring strategy reduces postpartum hypertension and cardiac remodelling
In women with elevated levels of blood pressure during pregnancy, the use of a physician-guided remote telemonitoring prog...
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