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Metabolic alterations in heart failure
Metabolic alterations in heart failure
Metabolic diseases are important risk factors for the development of heart failure, and energetic deficit and oxidative st...
Mechano-energetic uncoupling in heart failure
Mechano-energetic uncoupling in heart failure
Heart failure (HF) is a major global and life-threatening disease. Despite advances in therapies, the prevalence of HF is ...
Vascular (dys)function in the failing heart
Vascular (dys)function in the failing heart
Heart failure (HF) is not confined to contractile failure of cardiomyocytes or myocardial fibrosis. Coronary and systemic ...
Endothelial cell necroptosis induces haemolysis and microangiopathy
Endothelial cell necroptosis induces haemolysis and microangiopathy
Endothelial cells in ischaemic microvessels undergo necroptosis, which is linked to haemolysis and the deposition of&n...
Challenges and opportunities in assessing right ventricular structure and function: a Roadmap for standardization, clinical implementation and research
Challenges and opportunities in assessing right ventricular structure and function: a Roadmap for standardization, clinical implementation and research
Given its crucial role in determining patient symptoms and outcomes in various cardiopulmonary diseases, the thorough and ...
Tailored therapeutics for cardiomyopathies
Tailored therapeutics for cardiomyopathies
The term cardiomyopathy is used to describe a large family of complex heart muscle disorders of diverse aetiology and path...
Cardiodermatology: the heart of the connection between the skin and cardiovascular disease
Cardiodermatology: the heart of the connection between the skin and cardiovascular disease
The skin and cardiovascular systems are connected in unique and meaningful ways, and many diseases conventionally consider...
Improving English proficiency for scientific communication by non-fluent speakers
English has long been the dominant language in scientific communication. Although having a universal language for scientif...
Trade-offs between vessel-based and substrate-based nomenclatures for coronary heart diseases
Trade-offs between vessel-based and substrate-based nomenclatures for coronary heart diseases
Debate exists regarding the best terminology for common presentations of heart diseases caused by epicardial and/or microv...
Monocytes migrate to the brain after MI to promote deep sleep to aid cardiac healing
Monocytes migrate to the brain after MI to promote deep sleep to aid cardiac healing
After myocardial infarction, monocytes are actively recruited to the brain to augment sleep power and abundance, which in ...
Trials and tribulations of cell therapy for heart failure: an update on ongoing trials
Trials and tribulations of cell therapy for heart failure: an update on ongoing trials
Heart failure (HF) remains a leading cause of mortality, responsible for 13% of all deaths worldwide. The prognosis for pa...
Cholesterol crystals in the pathogenesis of atherosclerosis
Cholesterol crystals in the pathogenesis of atherosclerosis
The presence of cholesterol crystals (CCs) in tissues was first described more than 100 years ago. CCs have a pathogenic r...
Charting the future of cardiology with large language model artificial intelligence
Charting the future of cardiology with large language model artificial intelligence
Large language models represent a transformative leap in artificial intelligence and natural language processing, offering...
Unlocking excellence in health care: the power of inclusive and sensitive language in medicine
This call to action aims to increase awareness of inclusive language in medicine to enhance the experiences of patients an...
Dietary patterns to promote cardiometabolic health
Dietary patterns to promote cardiometabolic health
Multiple professional societies recommend the Mediterranean and/or Dietary Approaches to Stop Hypertension dietary pattern...
Functional control of myosin motors in the cardiac cycle
Functional control of myosin motors in the cardiac cycle
Contraction of the heart is driven by cyclical interactions between myosin and actin filaments powered by ATP hydrolysis. ...
Computational modelling of cardiovascular pathophysiology to risk stratify commercial spaceflight
Computational modelling of cardiovascular pathophysiology to risk stratify commercial spaceflight
For more than 60 years, humans have travelled into space. Until now, the majority of astronauts have been professional, go...
Cardiac sarcomere turnover by unidirectional replacement of proteins
Cardiac sarcomere turnover by unidirectional replacement of proteins
A new study indicates that proteins in the sarcomere complex are stochastically removed and degraded and are replaced by n...
Standardization and clinical applications of retinal imaging biomarkers for cardiovascular disease: a Roadmap from an NHLBI workshop
Standardization and clinical applications of retinal imaging biomarkers for cardiovascular disease: a Roadmap from an NHLBI workshop
The accessibility of the retina with the use of non-invasive and relatively low-cost ophthalmic imaging techniques and ana...
Reactive oxygen species in hypertension
Reactive oxygen species in hypertension
Hypertension is a leading risk factor for stroke, heart disease and chronic kidney disease. Multiple interacting factors a...
Epidemiology of cardiometabolic health in Latin America and strategies to address disparities
Epidemiology of cardiometabolic health in Latin America and strategies to address disparities
In Latin America and the Caribbean (LAC), sociodemographic context, socioeconomic disparities and the high level of urbani...
Potential new therapeutic target for HFpEF
Potential new therapeutic target for HFpEF
A new small-molecule inhibitor of vasohibins reduces myocardial stiffness and improves diastolic relaxation in a rat model...
Presence of microplastics in carotid plaques linked to cardiovascular events
In patients with carotid artery disease, the presence of microplastics and nanoplastics in the carotid plaque is associate...
Long-read sequencing provides insights into genetic influence
Long-read sequencing provides insights into genetic influence
In this Tools of the Trade article, Trivett discusses the potential of long-read sequencing in generating high-quality ref...
Protein glycosylation in cardiovascular health and disease
Protein glycosylation in cardiovascular health and disease
Protein glycosylation, which involves the attachment of carbohydrates to proteins, is one of the most abundant protein co-...
Non-coding RNAs as therapeutic targets and biomarkers in ischaemic heart disease
Non-coding RNAs as therapeutic targets and biomarkers in ischaemic heart disease
The adult heart is a complex, multicellular organ that is subjected to a series of regulatory stimuli and circuits and has...
Optimizing antithrombotic therapy in patients with coexisting cardiovascular and gastrointestinal disease
Optimizing antithrombotic therapy in patients with coexisting cardiovascular and gastrointestinal disease
Balancing the safety and efficacy of antithrombotic agents in patients with gastrointestinal disorders is challenging beca...
Author Correction: 2023 World Heart Federation guidelines for the echocardiographic diagnosis of rheumatic heart disease
Division of Adult Cardiology, Uganda Heart Institute, Kampala, UgandaJoselyn Rwebembera & Emmy OkelloGlobal and Tropic...
Contemporary pharmacological treatment and management of heart failure
Contemporary pharmacological treatment and management of heart failure
The prevention and treatment strategies for heart failure (HF) have evolved in the past two decades. The stages of HF have...
A newly identified gut hormone suppresses cholesterol production in the liver
A new study identifies a hormone that is secreted by the gut in response to cholesterol absorption and can inhibit cholest...
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