Shimizu I. Minamino T Physiological and pathological cardiac hypertrophy. J Mol Cell Cardiol. 2016;97:245–62.
Article CAS PubMed Google Scholar
Zhang Y, Da Q, Cao S, et al. HINT1 (histidine triad nucleotide-binding protein 1) attenuates cardiac hypertrophy via suppressing HOXA5 (Homeobox A5) expression. Circulation. 2021;144:638–54.
Article CAS PubMed Google Scholar
Marian AJ. Braunwald E Hypertrophic cardiomyopathy: genetics, pathogenesis, clinical manifestations, diagnosis, and therapy. Circ Res. 2017;121:749–70.
Article CAS PubMed PubMed Central Google Scholar
Nakamura M. Sadoshima J Mechanisms of physiological and pathological cardiac hypertrophy. Nat Rev Cardiol. 2018;15:387–407.
Article CAS PubMed Google Scholar
Backs J, Backs T, Neef S, et al. The delta isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload. Proc Natl Acad Sci U S A. 2009;106:2342–7.
Article CAS PubMed PubMed Central Google Scholar
Lee CF, Chavez JD, Garcia-Menendez L, et al. Normalization of NAD+ redox balance as a therapy for heart failure. Circulation. 2016;134:883–94.
Article CAS PubMed PubMed Central Google Scholar
Horton JL, Martin OJ, Lai L, et al. Mitochondrial protein hyperacetylation in the failing heart. JCI Insight. 2016;2(1):e84897.
Frieler RA. Mortensen RM Immune cell and other noncardiomyocyte regulation of cardiac hypertrophy and remodeling. Circulation. 2015;131:1019–30.
Article PubMed PubMed Central Google Scholar
Zhou L, Miao K, Yin B, et al. Cardioprotective role of myeloid-derived suppressor cells in heart failure. Circulation. 2018;138:181–97.
Article CAS PubMed Google Scholar
Raphael I, Nalawade S, Eagar TN, et al. T cell subsets and their signature cytokines in autoimmune and inflammatory diseases. Cytokine. 2015;74:5–17.
Article CAS PubMed Google Scholar
Hirahara K. Nakayama T CD4+ T-cell subsets in inflammatory diseases: beyond the Th1/Th2 paradigm. Int Immunol. 2016;28:163–71.
Article CAS PubMed PubMed Central Google Scholar
Saxena V, Lakhan R, Iyyathurai J, et al. Mechanisms of exTreg induction. Eur J Immunol. 2021;51:1956–67.
Article CAS PubMed PubMed Central Google Scholar
Kuan R, Agrawal DK. Thankam FG Treg cells in atherosclerosis. Mol Biol Rep. 2021;48:4897–910.
Article CAS PubMed Google Scholar
Shackleton EG, Ali HY, Khan M, et al. Novel combinatorial approaches to tackle the immunosuppressive microenvironment of prostate cancer. Cancers (Basel). 2021;13(5):1145.
Gouirand V, Habrylo I, Rosenblum MD. Regulatory T cells and inflammatory mediators in autoimmune disease. J Invest Dermatol. 2021;142(3 Pt B):774–780.
Volfson-Sedletsky V, Jones AT, Hernandez-Escalante J, et al. Emerging therapeutic strategies to restore regulatory T cell control of islet autoimmunity in type 1 diabetes. Front Immunol. 2021;12:635767.
Article CAS PubMed PubMed Central Google Scholar
Li J, Sha J, Sun L, et al. Contribution of regulatory T cell methylation modifications to the pathogenesis of allergic airway diseases. J Immunol Res. 2021;2021:5590217.
Article PubMed PubMed Central Google Scholar
Demosthenous C, Sakellari I, Douka V, et al. The role of myeloid-derived suppressor cells (MDSCs) in graft-versus-host disease (GVHD). J Clin Med. 2021;10(10):2050.
Boldison J, Long AE, Aitken RJ, et al. Activated but functionally impaired memory Tregs are expanded in slow progressors to type 1 diabetes. Diabetologia. 2022;65:343–55.
Article CAS PubMed Google Scholar
Li CR, Deiro MF, Godebu E, et al. IL-7 uniquely maintains FoxP3(+) adaptive Treg cells that reverse diabetes in NOD mice via integrin-β7-dependent localization. J Autoimmun. 2011;37:217–27.
Article CAS PubMed PubMed Central Google Scholar
Mhanna V, Fourcade G, Barennes P, et al. Impaired activated/memory regulatory T cell clonal expansion instigates diabetes in NOD mice. Diabetes. 2021;70:976–85.
Article CAS PubMed Google Scholar
Zhou X, Bailey-Bucktrout SL, Jeker LT, et al. Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo. Nat Immunol. 2009;10:1000–7.
Article CAS PubMed PubMed Central Google Scholar
Lee S, Bartlett B, Dwivedi G. Adaptive immune responses in human atherosclerosis. Int J Mol Sci. 2020;21(23):9322.
He X, Liang B. Gu N Th17/Treg imbalance and atherosclerosis. Dis Markers. 2020;2020:8821029.
Article PubMed PubMed Central Google Scholar
Ou HX, Guo BB, Liu Q, et al. Regulatory T cells as a new therapeutic target for atherosclerosis. Acta Pharmacol Sin. 2018;39:1249–58.
Article CAS PubMed PubMed Central Google Scholar
Bansal SS, Ismahil MA, Goel M, et al. Activated T lymphocytes are essential drivers of pathological remodeling in ischemic heart failure. Circ Heart Fail. 2017;10:e003688.
Article CAS PubMed PubMed Central Google Scholar
Feng G, Bajpai G, Ma P, et al. CCL17 aggravates myocardial injury by suppressing recruitment of regulatory T cells. Circulation. 2022;145:765–82.
Article CAS PubMed PubMed Central Google Scholar
Bansal SS, Ismahil MA, Goel M, et al. Dysfunctional and proinflammatory regulatory T-lymphocytes are essential for adverse cardiac remodeling in ischemic cardiomyopathy. Circulation. 2019;139:206–21.
Article CAS PubMed PubMed Central Google Scholar
Weirather J, Hofmann UD, Beyersdorf N, et al. Foxp3+ CD4+ T cells improve healing after myocardial infarction by modulating monocyte/macrophage differentiation. Circ Res. 2014;115:55–67.
Article CAS PubMed Google Scholar
Kvakan H, Kleinewietfeld M, Qadri F, et al. Regulatory T cells ameliorate angiotensin II-induced cardiac damage. Circulation. 2009;119:2904–12.
Article CAS PubMed Google Scholar
Oparil S, Acelajado MC, Bakris GL, et al. Hypertension Nat Rev Dis Primers. 2018;4:18014.
Levy D, Larson MG, Vasan RS, et al. The progression from hypertension to congestive heart failure. JAMA. 1996;275:1557–62.
Article CAS PubMed Google Scholar
Brenes-Castro D, Castillo EC, Vázquez-Garza E, et al. Temporal frame of immune cell infiltration during heart failure establishment: lessons from animal models. Int J Mol Sci. 2018;19(12):3719.
Rai A, Narisawa M, Li P, et al. Adaptive immune disorders in hypertension and heart failure: focusing on T-cell subset activation and clinical implications. J Hypertens. 2020;38:1878–89.
Article CAS PubMed Google Scholar
Viel EC, Lemarié CA, Benkirane K, et al. Immune regulation and vascular inflammation in genetic hypertension. Am J Physiol Heart Circ Physiol. 2010;298:H938-944.
Article CAS PubMed Google Scholar
Cu
Comments (0)