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Phantom imaging demonstration of positronium lifetime with a long axial field-of-view PET/CT and 124I
Phantom imaging demonstration of positronium lifetime with a long axial field-of-view PET/CT and 124I
Measuring the ortho-positronium (oPs) lifetime in human tissue bears the potential of adding clinically relevant informati...
Bridging physics and practice: evaluating sensitivity, septal penetration, and detector dead time in terbium-161 gamma-camera imaging
Bridging physics and practice: evaluating sensitivity, septal penetration, and detector dead time in terbium-161 gamma-camera imaging
Terbium-161 (161Tb) has emerged as a promising therapeutic radionuclide, yet standardized imaging guidelines are lacking. ...
Optimizing dosimetry in Y-90 microsphere radioembolization: GPU-accelerated Monte Carlo simulation versus conventional methods for high-volume setting
Optimizing dosimetry in Y-90 microsphere radioembolization: GPU-accelerated Monte Carlo simulation versus conventional methods for high-volume setting
Yttrium-90 (90Y) microsphere radioembolization has shown unique advantages in treating both primary and metastatic liver c...
Count-rate management in 131I SPECT/CT calibration
Count-rate management in 131I SPECT/CT calibration
System calibration is essential for accurate SPECT/CT dosimetry. However, count losses due to dead time and pulse pileup m...
A review of state-of-the-art resolution improvement techniques in SPECT imaging
A review of state-of-the-art resolution improvement techniques in SPECT imaging
Single photon emission computed tomography (SPECT), a technique capable of capturing functional and molecular information,...
Validation of a data-driven motion-compensated PET brain image reconstruction algorithm in clinical patients using four radiotracers
Validation of a data-driven motion-compensated PET brain image reconstruction algorithm in clinical patients using four radiotracers
Patients with dementia symptoms often struggle to limit movements during PET examinations, necessitating motion compensati...
Phantom-based investigation of block sequential regularised expectation maximisation (BSREM) reconstruction for zirconium-89 PET-CT for varied count levels
Phantom-based investigation of block sequential regularised expectation maximisation (BSREM) reconstruction for zirconium-89 PET-CT for varied count levels
Zirconium-89 (Zr-89) PET tracers have become increasingly significant in the field of nuclear medicine due to their 3-day ...
11C-CFT PET brain imaging in Parkinson’s disease using a total-body PET/CT scanner
11C-CFT PET brain imaging in Parkinson’s disease using a total-body PET/CT scanner
This study aimed to evaluate the feasibility of 11C-CFT PET brain imaging in Parkinson’s Disease using a total-body ...
Data-driven gating (DDG)-based motion match for improved CTAC registration
Data-driven gating (DDG)-based motion match for improved CTAC registration
Respiratory motion artefacts are a pitfall in thoracic PET/CT imaging. A source of these motion artefacts within PET image...
Evaluation of lesion contrast in the walk-through long axial FOV PET scanner simulated with XCAT anthropomorphic phantoms
Evaluation of lesion contrast in the walk-through long axial FOV PET scanner simulated with XCAT anthropomorphic phantoms
This study evaluates the lesion contrast in a cost-effective long axial field of view (FOV) PET scanner, called the walk-t...
Quantitative SPECT/CT imaging of actinium-225 for targeted alpha therapy of glioblastomas
Quantitative SPECT/CT imaging of actinium-225 for targeted alpha therapy of glioblastomas
A new, alternative option for patients with recurrent glioblastoma is targeted alpha therapy (TAT), in the form of a local...
The significance of partial volume effect on the estimation of hypoxic tumour volume with [18F]FMISO PET/CT
The significance of partial volume effect on the estimation of hypoxic tumour volume with [18F]FMISO PET/CT
The purpose of this study was to evaluate how a retrospective correction of the partial volume effect (PVE) in [18F]fluoro...
SLIC-Occ: functional segmentation of occupancy images improves precision of EC50 images
SLIC-Occ: functional segmentation of occupancy images improves precision of EC50 images
Drug occupancy studies with positron emission tomography imaging are used routinely in early phase drug development trials...
SAFIR-I: first NEMA NU 4-2008-based performance characterization
SAFIR-I: first NEMA NU 4-2008-based performance characterization
Small Animal Fast Insert for MRI detector I (SAFIR-I) is a novel Positron Emission Tomography insert for a $$7\,\hbox $$ B...
90Y SPECT scatter estimation and voxel dosimetry in radioembolization using a unified deep learning framework
90Y SPECT scatter estimation and voxel dosimetry in radioembolization using a unified deep learning framework
90Y SPECT-based dosimetry following radioembolization (RE) in liver malignancies is challenging due to the inherent scatte...
Clinical application of a population-based input function (PBIF) for a shortened dynamic whole-body FDG-PET/CT protocol in patients with metastatic melanoma treated by immunotherapy
Clinical application of a population-based input function (PBIF) for a shortened dynamic whole-body FDG-PET/CT protocol in patients with metastatic melanoma treated by immunotherapy
The aim was to investigate the feasibility of a shortened dynamic whole-body (dWB) FDG-PET/CT protocol and Patlak imaging ...
Accurate image derived input function in [18F]SynVesT-1 mouse studies using isoflurane and ketamine/xylazine anesthesia
Accurate image derived input function in [18F]SynVesT-1 mouse studies using isoflurane and ketamine/xylazine anesthesia
Kinetic modeling in positron emission tomography (PET) requires measurement of the tracer plasma activity in the absence o...
16-channel SiPM high-frequency readout with time-over-threshold discrimination for ultrafast time-of-flight applications
16-channel SiPM high-frequency readout with time-over-threshold discrimination for ultrafast time-of-flight applications
Over the past five years, ultrafast high-frequency (HF) readout concepts have advanced the timing performance of ...
Optimisation of the air fraction correction for lung PET/CT: addressing resolution mismatch
Optimisation of the air fraction correction for lung PET/CT: addressing resolution mismatch
Increased pulmonary $$^$$ F-FDG metabolism in patients with idiopathic pulmonary fibrosis, and other forms of diffuse pare...
A simulation study of the system characteristics for a long axial FOV PET design based on monolithic BGO flat panels compared with a pixelated LSO cylindrical design
A simulation study of the system characteristics for a long axial FOV PET design based on monolithic BGO flat panels compared with a pixelated LSO cylindrical design
Although a new generation of tomographs with a longer axial field-of-view called total-body PET have been developed, they ...
Correction: Precision dosimetry in yttrium-90 radioembolization through CT imaging of radiopaque microspheres in a rabbit liver model
Correction: Precision dosimetry in yttrium-90 radioembolization through CT imaging of radiopaque microspheres in a rabbit liver model
In this article [1], James J. Karnia at affiliation “Department of Veterinary Medicine and Surgery, University of Missouri...
Parametric and non-parametric Poisson regression for modelling of the arterial input function in positron emission tomography
Parametric and non-parametric Poisson regression for modelling of the arterial input function in positron emission tomography
Full quantification of Positron Emission Tomography (PET) requires an arterial input function (AIF) for measurement of cer...
On the use of solid 133Ba sources as surrogate for liquid 131I in SPECT/CT calibration: a European multi-centre evaluation
On the use of solid 133Ba sources as surrogate for liquid 131I in SPECT/CT calibration: a European multi-centre evaluation
Commissioning, calibration, and quality control procedures for nuclear medicine imaging systems are typically performed us...
Harmonization of brain PET images in multi-center PET studies using Hoffman phantom scan
Harmonization of brain PET images in multi-center PET studies using Hoffman phantom scan
Image harmonization has been proposed to minimize heterogeneity in brain PET scans acquired in multi-center studies. Howev...
Replacing Lu-177 with Tb-161 in DOTA-TATE and PSMA-617 therapy: potential dosimetric implications for activity selection
Replacing Lu-177 with Tb-161 in DOTA-TATE and PSMA-617 therapy: potential dosimetric implications for activity selection
To explore the dosimetric effect of substituting Lu-177 with Tb-161 in targeted radionuclide therapy (TRT) using the regis...
An automatic pipeline for PET/MRI attenuation correction validation in the brain
An automatic pipeline for PET/MRI attenuation correction validation in the brain
Challenges in PET/MRI quantitative accuracy for neurological uses arise from PET attenuation correction accuracy. We propo...
Radiation exposure assessment of nuclear medicine staff administering [177Lu]Lu-DOTA-TATE with active and passive dosimetry
Radiation exposure assessment of nuclear medicine staff administering [177Lu]Lu-DOTA-TATE with active and passive dosimetry
The use of lutetium-177 (177Lu)-based radiopharmaceuticals in peptide receptor nuclear therapy is increasing, but so is th...
Combining deep learning with a kinetic model to predict dynamic PET images and generate parametric images
Combining deep learning with a kinetic model to predict dynamic PET images and generate parametric images
Dynamic positron emission tomography (PET) images are useful in clinical practice because they can be used to calculate th...
Ultra-low-dose CT for attenuation correction: dose savings and effect on PET quantification for protocols with and without tin filter
Ultra-low-dose CT for attenuation correction: dose savings and effect on PET quantification for protocols with and without tin filter
Ultra-low-dose (ULD) computed tomography (CT) scans should be used when CT is performed only for attenuation correction (A...
Optimization of Q.Clear reconstruction for dynamic 18F PET imaging
Optimization of Q.Clear reconstruction for dynamic 18F PET imaging
Q.Clear, a Bayesian penalized likelihood reconstruction algorithm, has shown high potential in improving quantitation accu...
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