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Role of [18F]FAPI-04 in staging and therapeutic management of intrahepatic cholangiocarcinoma: prospective comparison with [18F]FDG PET/CT
Fluorine-18 fluorodeoxyglucose ([18F]FDG) positron emission tomography/computed tomography (PET/CT) has some limitations i...
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Prognostic evaluation in recurrent glioma through 11C-Choline PET/CT imaging
Glioma, a primary malignant tumor originating from glial cells, represents approximately 81% of intracranial malignant tum...
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Brain perfusion SPECT in the presurgical evaluation of epilepsy: is additional ictal SPECT required in case of high-confidence lateralization of the seizure onset zone by interictal SPECT and vice versa?
Ictal brain perfusion SPECT provides higher sensitivity for the identification of the epileptic seizure onset zone (SOZ) t...
Ejnmmi Research
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Potential application of [18F]AlF-PSMA-11 PET/CT in radioiodine refractory thyroid carcinoma
Patients diagnosed with radioiodine refractory (RAI-R) thyroid carcinoma (TC) have a significantly worse prognosis than pa...
Ejnmmi Research
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Quantitation of mitral regurgitation using positron emission tomography
Cardiac positron emission tomography (PET) offers non-invasive assessment of perfusion and left ventricular (LV) function ...
Ejnmmi Research
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Distinguishing thymic cysts from low-risk thymomas via [18F]FDG PET/CT
Thymic cysts are a rare benign disease that needs to be distinguished from low-risk thymoma. [18F]fluorodeoxyglucose (FDG)...
Ejnmmi Research
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In vivo assessment of safety, biodistribution, and radiation dosimetry of the [18F]Me4FDG PET-radiotracer in adults
Approaches targeting the sodium-glucose cotransporter (SGLT) could represent a promising future therapeutic strategy for n...
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Effect of radiation therapy on lymph node fluorescence in head and neck squamous cell carcinoma after intravenous injection of indocyanine green: a prospective evaluation
Indocyanine green (ICG)-guided surgery has proven effective in the identification of neoplastic tissues. The effect of rad...
Ejnmmi Research
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Radiation dosimetry of para-chloro-2-[18F]fluoroethyl-etomidate: a PET tracer for adrenocortical imaging
[11C]metomidate, a methyl ester analogue of etomidate, is used for positron emission tomography of adrenocortical cancer, ...
Ejnmmi Research
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PSMA imaging as a non-invasive tool to monitor inducible gene expression in vivo
Das A, Zhou X, Metz SW, Vink MA, Berkhout B. Selecting the optimal Tet-on system for doxycycline-inducible gene expression...
Ejnmmi Research
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[68 Ga]Ga-FAPI-04 PET/CT may be a predictor for early treatment response in rheumatoid arthritis
The identification of biomarkers predicting the treatment response of rheumatoid arthritis (RA) is important. [68 ...
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ImmunoPET provides a novel way to visualize the CD103+ tissue-resident memory T cell to predict the response of immune checkpoint inhibitors
Immune checkpoint inhibitors (ICIs) have made significant progress in oncotherapy improving survival of patients. However,...
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Effects of isoflurane anaesthesia depth and duration on renal function measured with [99mTc]Tc-mercaptoacetyltriglycine SPECT in mice
The influence of anaesthetic depth and the potential influence of different anaesthetic beds and thus different handling p...
Ejnmmi Research
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Comparison of tracer kinetic models for 68Ga-PSMA-11 PET in intermediate-risk primary prostate cancer patients
68Ga-PSMA-11 positron emission tomography enables the detection of primary, recurrent, and metastatic prostate cancer. Reg...
Ejnmmi Research
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18F-FDG PET/CT-based deep learning radiomics predicts 5-years disease-free survival after failure to achieve pathologic complete response to neoadjuvant chemotherapy in breast cancer
This study aimed to assess whether a combined model incorporating radiomic and depth features extracted from PET/CT can pr...
Ejnmmi Research
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Single time point quantitation of cerebral glucose metabolism by FDG-PET without arterial sampling
Until recently, quantitation of the net influx of 2-[18F]fluorodeoxyglucose (FDG) to brain (Ki) and the cerebrometabolic r...
Ejnmmi Research
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[18F]FDG PET-MR characterization of aortitis in the IL1rn−/− mouse model of giant-cell arteritis
Metabolic imaging is routinely used to demonstrate aortitis in patients with giant-cell arteritis. We aimed to investigate...
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Development of [89Zr]Zr-hCD103.Fab01A and [68Ga]Ga-hCD103.Fab01A for PET imaging to noninvasively assess cancer reactive T cell infiltration: Fab-based CD103 immunoPET
CD103 is an integrin specifically expressed on the surface of cancer-reactive T cells. The number of CD103+ T cells signif...
Ejnmmi Research
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Biological efficacy of simulated radiolabeled Lipiodol® ultra-fluid and microspheres for various beta emitters: study based on VX2 tumors
Radioembolization is one therapeutic option for the treatment of locally early-stage hepatocellular carcinoma. The aim of ...
Ejnmmi Research
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Assessment of hypoxia and oxidative-related changes in a lung-derived brain metastasis model by [64Cu][Cu(ATSM)] PET and proteomic studies
Brain metastases (BM) are the most frequent malignant brain tumors. The aim of this study was to characterize the tumor mi...
Ejnmmi Research
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Adenosine-induced splenic switch-off on [15O]H2O PET perfusion for the assessment of vascular vasodilatation
Splenic switch-off (SSO) is a marker of adequate adenosine-induced vasodilatation on cardiac magnetic resonance perfusion ...
Ejnmmi Research
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Characterisation of a novel [18F]FDG brain PET database and combination with a second database for optimising detection of focal abnormalities, using focal cortical dysplasia as an example
Brain [18F]FDG PET is used clinically mainly in the presurgical evaluation for epilepsy surgery and in the differential di...
Ejnmmi Research
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Heterogeneity of prostate-specific membrane antigen (PSMA) and PSMA-ligand uptake detection combining autoradiography and postoperative pathology in primary prostate cancer
Targeting prostate-specific membrane antigen (PSMA) has been highly successful for imaging and treatment of prostate cance...
Ejnmmi Research
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Head-to-head comparison of relative cerebral blood flow derived from dynamic [18F]florbetapir and [18F]flortaucipir PET in subjects with subjective cognitive decline
Dynamic PET imaging studies provide accurate estimates of specific binding, but also measure the relative tracer delivery ...
Ejnmmi Research
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Effects of novel androgen receptor signaling inhibitors on PSMA PET signal intensity in patients with castrate-resistant prostate cancer: a prospective exploratory serial imaging study
PSMA expression is influenced by hormonal status. We evaluated changes in PSA and whole-body 68Ga-PSMA-11 PET/CT (WB-PSMA ...
Ejnmmi Research
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An update on the use of image-derived input functions for human PET studies: new hopes or old illusions?
The need for arterial blood data in quantitative PET research limits the wider usability of this imaging method in clinica...
Ejnmmi Research
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Quantitative and clinical implications of the EARL2 versus EARL1 [18F]FDG PET-CT performance standards in head and neck squamous cell carcinoma
The EANM Research Ltd. (EARL) guidelines give recommendations for harmonization of [18F]FDG PET-CT image acquisition and r...
Ejnmmi Research
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Baseline 18F-FDG PET/CT radiomics for prognosis prediction in diffuse large B cell lymphoma
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma in adults. Standard treatment inc...
Ejnmmi Research
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Value of 18F-FDG-PET/CT radiomics combined with clinical variables in the differential diagnosis of malignant and benign vertebral compression fractures
Vertebral compression fractures (VCFs) are common clinical problems that arise from various reasons. The differential diag...
Ejnmmi Research
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Myocardial glucose suppression may interfere with the detection of inflammatory cells with FDG-PET as suggested in a canine model of myocardial infarction
After myocardial infarction, fibrosis and an ongoing dysregulated inflammatory response have been shown to lead to adverse...
Ejnmmi Research
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