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Pre-operative dual-time-point [18F]FET PET differentiates CDKN2A/B loss and PIK3CA mutation status in adult-type diffuse glioma: a single-center prospective study
Pre-operative dual-time-point [18F]FET PET differentiates CDKN2A/B loss and PIK3CA mutation status in adult-type diffuse glioma: a single-center prospective study
While [18F]FET PET plays a complementary role in glioma imaging, it needs to be more comprehensively understood for improv...
Pre-treatment [18F]FDG PET/CT biomarkers for the prediction of antibody–drug conjugates efficacy in metastatic breast cancer
Pre-treatment [18F]FDG PET/CT biomarkers for the prediction of antibody–drug conjugates efficacy in metastatic breast cancer
This study aimed to evaluate the association between pretreatment [18F]FDG PET/CT-derived biomarkers and outcomes in metas...
[18F]FDG PET for mapping the cerebral glucose metabolic characteristics of drug-sensitive and drug-resistant epilepsy in pediatric patients
[18F]FDG PET for mapping the cerebral glucose metabolic characteristics of drug-sensitive and drug-resistant epilepsy in pediatric patients
This study aimed to investigate [18F]fluorodeoxyglucose positron emission tomography ([18F]FDG PET) mapping for cerebral g...
Pharmacokinetic analysis and simplified uptake measures for tumour lesion [18F]F-AraG PET imaging in patients with non-small cell lung cancer
Pharmacokinetic analysis and simplified uptake measures for tumour lesion [18F]F-AraG PET imaging in patients with non-small cell lung cancer
The novel positron emission tomography (PET) imaging tracer, [18F]F-AraG, targets activated T-cells, offering a potential ...
Preclinical evaluation and pilot clinical study of [68Ga]Ga-NOTA-H006 for non-invasive PET imaging of 5T4 oncofetal antigen
Preclinical evaluation and pilot clinical study of [68Ga]Ga-NOTA-H006 for non-invasive PET imaging of 5T4 oncofetal antigen
Trophoblast glycoprotein, the so-called 5T4, is an oncofetal antigen expressed in many different cancers. However, no 5T4-...
Spiral volumetric optoacoustic tomography of reduced oxygen saturation in the spinal cord of M83 mouse model of Parkinson’s disease
Spiral volumetric optoacoustic tomography of reduced oxygen saturation in the spinal cord of M83 mouse model of Parkinson’s disease
Metabolism and bioenergetics in the central nervous system play important roles in the pathophysiology of Parkinson’...
Fluorescence detection of pituitary neuroendocrine tumour during endoscopic transsphenoidal surgery using bevacizumab-800CW: a non-randomised, non-blinded, single centre feasibility and dose finding trial [DEPARTURE trial]
Fluorescence detection of pituitary neuroendocrine tumour during endoscopic transsphenoidal surgery using bevacizumab-800CW: a non-randomised, non-blinded, single centre feasibility and dose finding trial [DEPARTURE trial]
Achieving endocrine remission by gross total resection is challenging in pituitary neuroendocrine tumours (PitNETs) with c...
Preclinical evaluation of 225Ac-labeled minigastrin analog DOTA-CCK-66 for Targeted Alpha Therapy
Preclinical evaluation of 225Ac-labeled minigastrin analog DOTA-CCK-66 for Targeted Alpha Therapy
The recently developed metabolically more stable minigastrin derivative, DOTA-CCK-66, displayed promising preclinical data...
Novel astatine (211At)-labelled prostate-specific membrane antigen ligand with a neopentyl-glycol structure: evaluation of stability, efficacy, and safety using a prostate cancer xenograft model
Novel astatine (211At)-labelled prostate-specific membrane antigen ligand with a neopentyl-glycol structure: evaluation of stability, efficacy, and safety using a prostate cancer xenograft model
Prostate-specific membrane antigen (PSMA)-targeted alpha therapy is considered a promising alternative treatment for metas...
[68Ga]Ga-FAPI versus [18F]FDG PET/CT in the evaluation of Langerhans cell histiocytosis
[68Ga]Ga-FAPI versus [18F]FDG PET/CT in the evaluation of Langerhans cell histiocytosis
Ethics approval and consent to participate All procedures p...
Intelligent ultrafast total-body PET for sedation-free pediatric [18F]FDG imaging
Intelligent ultrafast total-body PET for sedation-free pediatric [18F]FDG imaging
This study aims to develop deep learning techniques on total-body PET to bolster the feasibility of sedation-free pediatri...
The superior detection rate of total-body [68Ga]Ga-PSMA-11 PET/CT compared to short axial field-of-view [68Ga]Ga-PSMA-11 PET/CT for early recurrent prostate cancer patients with PSA < 0.2 ng/mL after radical prostatectomy
The superior detection rate of total-body [68Ga]Ga-PSMA-11 PET/CT compared to short axial field-of-view [68Ga]Ga-PSMA-11 PET/CT for early recurrent prostate cancer patients with PSA < 0.2 ng/mL after radical prostatectomy
[68Ga]Ga-PSMA PET imaging has been extensively utilized for the detection of biochemical recurrence (BCR) in prostate canc...
Targeted interleukin-2 enhances the in vivo anti-cancer activity of Pluvicto™
Targeted interleukin-2 enhances the in vivo anti-cancer activity of Pluvicto™
Pluvicto™ ([177Lu]Lu-PSMA-617), a radioligand therapeutic targeting prostate-specific membrane antigen (PSMA), has b...
Tau aggregation following subcortical hemorrhage
Tau aggregation following subcortical hemorrhage
Conflict of interest AD: Research support: Siemens Healthin...
First-in-human administration of terbium-161-labelled somatostatin receptor subtype 2 antagonist ([161Tb]Tb-DOTA-LM3) in a patient with a metastatic neuroendocrine tumour of the ileum
First-in-human administration of terbium-161-labelled somatostatin receptor subtype 2 antagonist ([161Tb]Tb-DOTA-LM3) in a patient with a metastatic neuroendocrine tumour of the ileum
Ethics approval This study was performed in line with the p...
[18F]FDG PET/CT for prognosis and toxicity prediction of diffuse large B-cell lymphoma patients with chimeric antigen receptor T-cell therapy
[18F]FDG PET/CT for prognosis and toxicity prediction of diffuse large B-cell lymphoma patients with chimeric antigen receptor T-cell therapy
Chimeric antigen receptor (CAR) T-cell therapy has been confirmed to benefit patients with relapsed and/or refractory diff...
EANM position on positron emission tomography in suspected functional pituitary neuroendocrine tumours
EANM position on positron emission tomography in suspected functional pituitary neuroendocrine tumours
Asa SL, Mete O, Perry A, Osamura RY. Overview of the 2022 WHO classification of Pituitary tumors. Endocr Pathol. 2022;33:6...
ImmunoPET/CT imaging of clear cell renal cell carcinoma with [18F]RCCB6: a first-in-human study
ImmunoPET/CT imaging of clear cell renal cell carcinoma with [18F]RCCB6: a first-in-human study
The cluster of differentiation (CD70) is a potential biomarker of clear cell renal cell carcinoma (ccRCC). This study aims...
Image-based dosimetry for [225Ac]Ac-PSMA-I&T therapy and the effect of daughter-specific pharmacokinetics
Image-based dosimetry for [225Ac]Ac-PSMA-I&T therapy and the effect of daughter-specific pharmacokinetics
Although 221Fr and 213Bi have sufficient gamma emission probabilities, quantitative SPECT after [225Ac]Ac-PSMA-I&amp;T...
Disrupted gut microecology after high-dose 131I therapy and radioprotective effects of arachidonic acid supplementation
Disrupted gut microecology after high-dose 131I therapy and radioprotective effects of arachidonic acid supplementation
Despite the potential radiotoxicity in differentiated thyroid cancer (DTC) patients with high-dose 131I therapy, the alter...
Macrophage mannose receptor CD206 targeting of fluoride-18 labeled mannosylated dextran: A validation study in mice
Macrophage mannose receptor CD206 targeting of fluoride-18 labeled mannosylated dextran: A validation study in mice
Aluminum fluoride-18-labeled 1,4,7-triazacyclononane-1,4,7-triacetic acid-conjugated mannosylated dextran derivative (Al[1...
MET-receptor targeted fluorescent imaging and spectroscopy to detect multifocal papillary thyroid cancer
MET-receptor targeted fluorescent imaging and spectroscopy to detect multifocal papillary thyroid cancer
Multifocal disease in PTC is associated with an increased recurrence rate. Multifocal disease (MD) is underdiagnosed with ...
How nuclear imaging changed parathyroid surgical strategies through time
How nuclear imaging changed parathyroid surgical strategies through time
Mohebati A, Shaha AR. Imaging techniques in parathyroid surgery for primary hyperparathyroidism. 2011. https://doi.org/10....
Nuclear imaging in the new ESC Guidelines: the age of maturity
Nuclear imaging in the new ESC Guidelines: the age of maturity
“Cardiomyopathy refers to a myocardial disorder characterized by structural and functional abnormalities in the heart musc...
The value of [18F]FET PET and somatostatin receptor imaging for differentiating pseudoprogression in residual meningioma
The value of [18F]FET PET and somatostatin receptor imaging for differentiating pseudoprogression in residual meningioma
An 84-year-old male presented with transitional meningioma WHO° 1 (Figure part A, prior to resection). After completed the...
Comparison of the diagnostic value of [68 Ga]Ga-FAPI-04 PET/MR and [18F]FDG PET/CT in patients with T stage ≤ 2a2 uterine cervical cancer: a prospective study
Comparison of the diagnostic value of [68 Ga]Ga-FAPI-04 PET/MR and [18F]FDG PET/CT in patients with T stage ≤ 2a2 uterine cervical cancer: a prospective study
To compare the diagnostic value of [68&nbsp;Ga]Ga-FAPI-04 PET/MR and [18F]FDG PET/CT in patients with T stage &#...
FDG-PET/CT for investigation of pyrexia of unknown origin: a cost of illness analysis
FDG-PET/CT for investigation of pyrexia of unknown origin: a cost of illness analysis
Our study aims to explore the current utilisation of 18F-fluorodeoxyglucose positron emission tomography/computed tomograp...
[177Lu]Lu-labeled anti-claudin-18.2 antibody demonstrated radioimmunotherapy potential in gastric cancer mouse xenograft models
[177Lu]Lu-labeled anti-claudin-18.2 antibody demonstrated radioimmunotherapy potential in gastric cancer mouse xenograft models
Gastric cancer (GC), one of the most prevalent and deadliest tumors worldwide, is often diagnosed at an advanced stage wit...
The 16th Hangzhou International Molecular Imaging Conference (HIMIC 2023): the milestone of molecular imaging journey in China
The 16th Hangzhou International Molecular Imaging Conference (HIMIC 2023): the milestone of molecular imaging journey in China
The field of molecular imaging in China has been evolving with developmental progress...
Deep learning–based whole-body characterization of prostate cancer lesions on [68Ga]Ga-PSMA-11 PET/CT in patients with post-prostatectomy recurrence
Deep learning–based whole-body characterization of prostate cancer lesions on [68Ga]Ga-PSMA-11 PET/CT in patients with post-prostatectomy recurrence
The automatic segmentation and detection of prostate cancer (PC) lesions throughout the body are extremely challenging due...
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